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The map label for this gene is xerD [H]

Identifier: 108563083

GI number: 108563083

Start: 688821

End: 689891

Strand: Direct

Name: xerD [H]

Synonym: HPAG1_0658

Alternate gene names: 108563083

Gene position: 688821-689891 (Clockwise)

Preceding gene: 108563082

Following gene: 108563093

Centisome position: 43.15

GC content: 38.47

Gene sequence:

>1071_bases
ATGAAGCACCCCCTAGAAGAATTAAAAGACCCTGTAGAAAATCTTTTGCTGTGGATTGGGCGCTTTTTGCGCTACAAATG
CACGAGCCTGTCTAATTCCCAAGTGAAAGATCAAAACAAGGTTTTTGAATGCTTGAACGAATTCAATCATGCGTTCATCA
ATTCAAGCCAATTAGAAAAAGTTTGCAAAAAAGCCCGTAATGTTGGATTACTAGGTATCAACACCTACGCACTGCCCCTA
CTCAAATTTCACGAATACGCTCAAAAGCTTTCTTTAAAATCGCTCAAAAGCATTGATGAAGTCATGCTGGCTGAATTTTT
GAGTGTTTATACCGGGGGTTTGAGTTTAGCCACTAAGAAAAATTACAGAATCGCTCTACTCGGGCTTTTTAGCTACATAG
ACAAGCAAAATCAAGATGAAAATGAAAAATCTTATATCTATAATATCACGCTTAAAAATATCAGCGGAGTCAATCAAAGC
GCGGGCAACAAGCTCCCTACTCATTTAAACAATGAAGAATTAGAAAAATTTTTAGAGGGCATTGATAAAATAGAAATGTC
CGCTAAAGTGCGCGCCAGAAACCGCCTGCTCATTAAAATCATCGTTTTTACAGGCATGCGTTCCAATGAAGCCTTACAGC
TTAAAATAAAGGATTTTACTTTAGAAAATGGTTGTTATACGATTTTGATTAAAGGTAAGGGCGATAAATACAGGGCGGTG
ATGCTCAAAGCTTTTCATATTGAGAGCCTTTTAAAAGAATGGCTCACAGAAAGGGAATTATATCCTGTTAAAAACGATTT
ATTGTTTTGCAACCAAAAAGGCAGTGCTTTAACGCAAGCTTATTTGTATAAGCAAGTGGAGCGCATCATCAATTTTGCAG
GACTCAGGCGGGAGAAAAATGGGGCGCACATGTTAAGGCATTCTTTTGCGACCTTGCTTTATCAAAAACGCCATGATTTG
ATTTTAGTTCAAGAAGCTCTAGGGCATGCGAGCTTGAATACCAGTAGGATTTACACGCATTTTGACAAGCAGCGTTTAGA
AGAAGCGGCGAGCATTTGGGAAGAAAATTAA

Upstream 100 bases:

>100_bases
AGCGAAATTCATAGTGTTTGTAGCGAAAATTCTTTAATATGTCATCTTAATCAAGGTTCTTATATCATTGATTTGCACTT
AATAGATGACTAAACCCTAA

Downstream 100 bases:

>100_bases
AAACACCCCCTACCCCCTTAAAAAAAAGGATTTTTACCATAAAACAACCAAAACCCCATTTTTTAAGAAATCAAAGAGTT
TTTAGCCTGCTCATTTAAAA

Product: integrase-recombinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKHPLEELKDPVENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNEFNHAFINSSQLEKVCKKARNVGLLGINTYALPL
LKFHEYAQKLSLKSLKSIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQS
AGNKLPTHLNNEELEKFLEGIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
MLKAFHIESLLKEWLTERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDL
ILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN

Sequences:

>Translated_356_residues
MKHPLEELKDPVENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNEFNHAFINSSQLEKVCKKARNVGLLGINTYALPL
LKFHEYAQKLSLKSLKSIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQS
AGNKLPTHLNNEELEKFLEGIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
MLKAFHIESLLKEWLTERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDL
ILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN
>Mature_356_residues
MKHPLEELKDPVENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNEFNHAFINSSQLEKVCKKARNVGLLGINTYALPL
LKFHEYAQKLSLKSLKSIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQS
AGNKLPTHLNNEELEKFLEGIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
MLKAFHIESLLKEWLTERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDL
ILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=269, Percent_Identity=28.996282527881, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790244, Length=273, Percent_Identity=27.8388278388278, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790767, Length=196, Percent_Identity=29.0816326530612, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 41157; Mature: 41157

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHPLEELKDPVENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNEFNHAFINSSQLEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
VCKKARNVGLLGINTYALPLLKFHEYAQKLSLKSLKSIDEVMLAEFLSVYTGGLSLATKK
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
NYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQSAGNKLPTHLNNEELEKFLEG
CCEEHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
IDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
HHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEEEEEEECCCEEEEEEECCCCCCHHH
MLKAFHIESLLKEWLTERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKN
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN
HHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHPLEELKDPVENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNEFNHAFINSSQLEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
VCKKARNVGLLGINTYALPLLKFHEYAQKLSLKSLKSIDEVMLAEFLSVYTGGLSLATKK
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
NYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQSAGNKLPTHLNNEELEKFLEG
CCEEHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
IDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
HHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEEEEEEECCCEEEEEEECCCCCCHHH
MLKAFHIESLLKEWLTERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKN
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN
HHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]