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The map label for this gene is nupX [H]

Identifier: 107023143

GI number: 107023143

Start: 1765861

End: 1767135

Strand: Reverse

Name: nupX [H]

Synonym: Bcen_1592

Alternate gene names: 107023143

Gene position: 1767135-1765861 (Counterclockwise)

Preceding gene: 107023144

Following gene: 107023142

Centisome position: 53.64

GC content: 66.98

Gene sequence:

>1275_bases
GTGGATATTCTGCGCAGTCTCCTCGGCATGCTGTTTCTGTTGCTGGTCGCGTATCTGCTGTCGAACAACCGTCGTGCGGT
CAGCGCGCGGACCATGATCGCCGCGCTGCTCACGCAGTTCGCGATCGGTGCGCTCGTGCTGTTCGTGCCGTCGGGCCGCG
CGGCGCTGGCCGGGGCCGCGAACGGCGTCAATCGCGTGCTCGACATGGGCAATCACGGCATCGCGTTCGTGTTCGGCGGG
CTGGTCGACGCGCGCATGTTCCAGTTGTTCGGCGACGGCGGGTTCGTGTTCGGCCTGCGCGTGCTGCCGATGATCATCTT
CGTCACCGCGCTGATCTCGGTGCTGTACTACATCGGCGTGATGAAGTGGATCGTCGCGATCCTCGGCGCGGGGTTGGCGA
AGGTGCTCGGCGTGAGTCGCATCGAGGCATGCTCGGCCGTCGCGACGATCTTCCTCGGGCAGAGCGAGATGCCCGCGCTC
GTGAAGCCGTTCGTGCGCAACATGACGAGCGCCGAGATCTTCACGGTGATGGCGAGCGGGATGGCGTCGGTCGCGGGCTC
GGTGCTGGTCGGCTATGCCGGCCTCGGCGTGAAGATGGAGTACCTGCTCGCCGCGTCGTTCATGGCGGTGCCGGGCGGGC
TGCTGTTCGGCAAGCTGCTGTTTCCGACCGTCGAGCCGAGCCGCGTGGTGGTCGATGGCCTCGATTTCGACGACAAGCGC
GCCGCCAACGTGATCGAGGCGGCCGCCTCCGGTGCATCGGTCGGCCTGCGCATCGCGATCAACGTCGGCGCGATGCTGAT
CGCGTTCGTCGGGCTCATCGCGCTGATGAACCTGATCGTCGGCGGCGCGGCCGCGTTCGCGGGCTTTCCGCAGGTAACGC
TGGTCGGTATCATCGGCCATCTGTTCGCGCCGCTCGCATGGATCATCGGCGTGCCGTGGCACGATGCGACGCTGGCCGGC
AACTTCATCGGCGAGAAACTGATCTTCAACGAATTCGTCGCGTACGGCGACCTGTCGCCGTACCTGAAGGGTGGCGCGCA
CGCGGCGGCGGCCGGCCTGCAGGTGCTCGACCCGAAGACGCTCGCGATCGTATCGTTCGCGCTGTGCGGCTTCGCGAACT
TCTCGTCGATCGCGATTCTCGCGGGCGGCTTCAGCGCGGTCGCGCCCGAACGCCGTTCGGACGTCGCGCGGCTCGGCTTG
CGCGCGCTGACGGCCGCGACGCTGTCGAACCTGATGAGCGCGGCGATTGCCGGCCTGTTTTTCTCGCTGCATTGA

Upstream 100 bases:

>100_bases
GGCGCGCATATCGAGCGAGTAACATCCACCAACCCGATCGCACGGGTCGCGGGCACGGGCCGCCCGCCGGACAGTTCAAA
TAGTGAGAAAGGAGCACAAG

Downstream 100 bases:

>100_bases
ACCGTACAGTCGACTCCGATCGAAGCGAGGCAACGATGTTTCTACCGCAGGAATTCATTCGCAGGAAGCGTGACGGGCAG
CCGCTCGATCGCGACGACAT

Product: Na+ dependent nucleoside transporter-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MDILRSLLGMLFLLLVAYLLSNNRRAVSARTMIAALLTQFAIGALVLFVPSGRAALAGAANGVNRVLDMGNHGIAFVFGG
LVDARMFQLFGDGGFVFGLRVLPMIIFVTALISVLYYIGVMKWIVAILGAGLAKVLGVSRIEACSAVATIFLGQSEMPAL
VKPFVRNMTSAEIFTVMASGMASVAGSVLVGYAGLGVKMEYLLAASFMAVPGGLLFGKLLFPTVEPSRVVVDGLDFDDKR
AANVIEAAASGASVGLRIAINVGAMLIAFVGLIALMNLIVGGAAAFAGFPQVTLVGIIGHLFAPLAWIIGVPWHDATLAG
NFIGEKLIFNEFVAYGDLSPYLKGGAHAAAAGLQVLDPKTLAIVSFALCGFANFSSIAILAGGFSAVAPERRSDVARLGL
RALTAATLSNLMSAAIAGLFFSLH

Sequences:

>Translated_424_residues
MDILRSLLGMLFLLLVAYLLSNNRRAVSARTMIAALLTQFAIGALVLFVPSGRAALAGAANGVNRVLDMGNHGIAFVFGG
LVDARMFQLFGDGGFVFGLRVLPMIIFVTALISVLYYIGVMKWIVAILGAGLAKVLGVSRIEACSAVATIFLGQSEMPAL
VKPFVRNMTSAEIFTVMASGMASVAGSVLVGYAGLGVKMEYLLAASFMAVPGGLLFGKLLFPTVEPSRVVVDGLDFDDKR
AANVIEAAASGASVGLRIAINVGAMLIAFVGLIALMNLIVGGAAAFAGFPQVTLVGIIGHLFAPLAWIIGVPWHDATLAG
NFIGEKLIFNEFVAYGDLSPYLKGGAHAAAAGLQVLDPKTLAIVSFALCGFANFSSIAILAGGFSAVAPERRSDVARLGL
RALTAATLSNLMSAAIAGLFFSLH
>Mature_424_residues
MDILRSLLGMLFLLLVAYLLSNNRRAVSARTMIAALLTQFAIGALVLFVPSGRAALAGAANGVNRVLDMGNHGIAFVFGG
LVDARMFQLFGDGGFVFGLRVLPMIIFVTALISVLYYIGVMKWIVAILGAGLAKVLGVSRIEACSAVATIFLGQSEMPAL
VKPFVRNMTSAEIFTVMASGMASVAGSVLVGYAGLGVKMEYLLAASFMAVPGGLLFGKLLFPTVEPSRVVVDGLDFDDKR
AANVIEAAASGASVGLRIAINVGAMLIAFVGLIALMNLIVGGAAAFAGFPQVTLVGIIGHLFAPLAWIIGVPWHDATLAG
NFIGEKLIFNEFVAYGDLSPYLKGGAHAAAAGLQVLDPKTLAIVSFALCGFANFSSIAILAGGFSAVAPERRSDVARLGL
RALTAATLSNLMSAAIAGLFFSLH

Specific function: Nucleoside transporter [H]

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=425, Percent_Identity=33.4117647058824, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI11545853, Length=365, Percent_Identity=34.7945205479452, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI227116277, Length=418, Percent_Identity=33.4928229665072, Blast_Score=229, Evalue=3e-60,
Organism=Escherichia coli, GI1788485, Length=423, Percent_Identity=54.6099290780142, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1788488, Length=423, Percent_Identity=54.6099290780142, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1788737, Length=421, Percent_Identity=29.9287410926366, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71991794, Length=421, Percent_Identity=30.166270783848, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17560276, Length=405, Percent_Identity=28.3950617283951, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI25146537, Length=216, Percent_Identity=28.2407407407407, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45552519, Length=417, Percent_Identity=35.7314148681055, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI45552517, Length=417, Percent_Identity=35.7314148681055, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI19921868, Length=417, Percent_Identity=35.7314148681055, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI281360430, Length=413, Percent_Identity=31.9612590799031, Blast_Score=215, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43948; Mature: 43948

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILRSLLGMLFLLLVAYLLSNNRRAVSARTMIAALLTQFAIGALVLFVPSGRAALAGAA
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHH
NGVNRVLDMGNHGIAFVFGGLVDARMFQLFGDGGFVFGLRVLPMIIFVTALISVLYYIGV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MKWIVAILGAGLAKVLGVSRIEACSAVATIFLGQSEMPALVKPFVRNMTSAEIFTVMASG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
MASVAGSVLVGYAGLGVKMEYLLAASFMAVPGGLLFGKLLFPTVEPSRVVVDGLDFDDKR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCHH
AANVIEAAASGASVGLRIAINVGAMLIAFVGLIALMNLIVGGAAAFAGFPQVTLVGIIGH
HHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LFAPLAWIIGVPWHDATLAGNFIGEKLIFNEFVAYGDLSPYLKGGAHAAAAGLQVLDPKT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCCCHHCCCHH
LAIVSFALCGFANFSSIAILAGGFSAVAPERRSDVARLGLRALTAATLSNLMSAAIAGLF
HHHHHHHHHCCCCCCCHHHEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLH
HHCC
>Mature Secondary Structure
MDILRSLLGMLFLLLVAYLLSNNRRAVSARTMIAALLTQFAIGALVLFVPSGRAALAGAA
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHH
NGVNRVLDMGNHGIAFVFGGLVDARMFQLFGDGGFVFGLRVLPMIIFVTALISVLYYIGV
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MKWIVAILGAGLAKVLGVSRIEACSAVATIFLGQSEMPALVKPFVRNMTSAEIFTVMASG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
MASVAGSVLVGYAGLGVKMEYLLAASFMAVPGGLLFGKLLFPTVEPSRVVVDGLDFDDKR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCHH
AANVIEAAASGASVGLRIAINVGAMLIAFVGLIALMNLIVGGAAAFAGFPQVTLVGIIGH
HHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LFAPLAWIIGVPWHDATLAGNFIGEKLIFNEFVAYGDLSPYLKGGAHAAAAGLQVLDPKT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHCCCHHCCCHH
LAIVSFALCGFANFSSIAILAGGFSAVAPERRSDVARLGLRALTAATLSNLMSAAIAGLF
HHHHHHHHHCCCCCCCHHHEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLH
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]