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The map label for this gene is argD [H]

Identifier: 107022982

GI number: 107022982

Start: 1582938

End: 1584284

Strand: Reverse

Name: argD [H]

Synonym: Bcen_1430

Alternate gene names: 107022982

Gene position: 1584284-1582938 (Counterclockwise)

Preceding gene: 107022984

Following gene: 107022981

Centisome position: 48.09

GC content: 67.85

Gene sequence:

>1347_bases
ATGGATCTCAGTATTCACGGCGAGTCGAATCCCGCGCTCGCGTCGTCGTTTCGAAAGGTGCTCGTGCCCTGGGCGGTCCA
GGGCGGGCTCAATCCGCCGGTCATCACGCATGCGCAGGGATGCTACTTCTACGATGCGAACGGCAAGCGCTACCTGGACC
TCACCAGCGGCTATGTCGCGGTGTCGTTGGGACATGGCCATCCGAAGGTGGTCGAGGCGATCCAGGCGCAGGCCGCGCGC
ATGTGCTGGGTCGCGTCCAGCTACTTCAACGACGTGCGCGCCGAATACGCGGAACTCCTGAACAGCGTTTCGCCGTGGCC
GGACGGGCTGCGCGTGCATTTCACCTGCGGCGGTGCCGAGGCGAACGACGACGCGGTGAAGATCGCGCGGCTGGTGACAC
GCCGGCCCAAGGTGCTGACCGCCTATCGGTCGTATCACGGCAGCACGCTCGGCGCGAGCGCGATGACGGGCGTGGACCGC
TGGCGCGATCCGTTCCCGGCGCTGCCGGGCATGGTGAAGTTCTTTGCGCCGTATCCGTATCGCAGCCCGTTCCATACGTC
GGAGCCGGCCGAGGAAACCCGGCGCGCCCTCGATCACCTGGCGCGTGTCCTTTCGCATGAAGGCGCCCAAAACGTCGCCG
CGATCCTGATGGAGCCGATGACCGGCTCCAGCGGGGTCGTCGTCTACCCGCCGGGCTATCTCGCGGGCGTTCGGGATCTG
TGCGACCGGCACGGCATCCTGCTGATCTTCGACGAGGTCATGACGGGCTTCGGGCGCACGGGGGCATTGTTCTGCGCCGA
GCGGGTCGGCGTGTTGCCGGACCTGATTTCGTTCGCCAAGGGGGCCAGCTCTTCGTATACGCCCCTTGGCGGCGTCCTGG
TGCGCGAAGGTGTGGCCCGCCACTTCGATACGGAACTCTTCGACGTAGGCCACACGCATGCGGGCCACGTACTGGCGGTC
GCCGGCGGGCTCGCCGCGCTGAAGGTCTATCTGGAAGAGGGCTTGTTCGAGCGGGCGCGCGAGATCGAAGGCTGGCTGCG
CGACGGTCTCGGCGAGCTGGCGGAGCGTCATCCGTCGATCGGCGACGTGCGGGGCATGGGCGCCCAGTTCGGCATCGAGC
TGGTGCGCGACCGGGAAACGCGCGAGCCGCTCGTCGAGTGGCACCACCCGGCGGGATCGGCGCCGATGCGCGCGTTCTAT
GGCGAACTGCTGAAGCGCGGCGTTCACGCGTACGGGCGCTACAACGTGGTGATCGTGACGCCGCCGCTCGTCATCTCGCG
CACGGAGCTGGACGAGGGACTGGATGCGCTCGACGCGGCGCTGACGGTGCTGGAGGCCGCGCGATGA

Upstream 100 bases:

>100_bases
TGGAAACGTTTGATTTGTTGCGCGGGAAAGGCGTGCTTAATCTACAAGCCTCCTGTCACGAGGCTCAGAAATAGTGAGCC
ATGCCATTTCCGGAGTCAAC

Downstream 100 bases:

>100_bases
ACTATGAGGACATTCTGTATCGCGAAGCGGGCGGCGTGGCGACGATCACGATCAACCGTCCGTCGGTGTACAACGCGTTC
CGCGCCAGGACGGTCGACGA

Product: hypothetical protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MDLSIHGESNPALASSFRKVLVPWAVQGGLNPPVITHAQGCYFYDANGKRYLDLTSGYVAVSLGHGHPKVVEAIQAQAAR
MCWVASSYFNDVRAEYAELLNSVSPWPDGLRVHFTCGGAEANDDAVKIARLVTRRPKVLTAYRSYHGSTLGASAMTGVDR
WRDPFPALPGMVKFFAPYPYRSPFHTSEPAEETRRALDHLARVLSHEGAQNVAAILMEPMTGSSGVVVYPPGYLAGVRDL
CDRHGILLIFDEVMTGFGRTGALFCAERVGVLPDLISFAKGASSSYTPLGGVLVREGVARHFDTELFDVGHTHAGHVLAV
AGGLAALKVYLEEGLFERAREIEGWLRDGLGELAERHPSIGDVRGMGAQFGIELVRDRETREPLVEWHHPAGSAPMRAFY
GELLKRGVHAYGRYNVVIVTPPLVISRTELDEGLDALDAALTVLEAAR

Sequences:

>Translated_448_residues
MDLSIHGESNPALASSFRKVLVPWAVQGGLNPPVITHAQGCYFYDANGKRYLDLTSGYVAVSLGHGHPKVVEAIQAQAAR
MCWVASSYFNDVRAEYAELLNSVSPWPDGLRVHFTCGGAEANDDAVKIARLVTRRPKVLTAYRSYHGSTLGASAMTGVDR
WRDPFPALPGMVKFFAPYPYRSPFHTSEPAEETRRALDHLARVLSHEGAQNVAAILMEPMTGSSGVVVYPPGYLAGVRDL
CDRHGILLIFDEVMTGFGRTGALFCAERVGVLPDLISFAKGASSSYTPLGGVLVREGVARHFDTELFDVGHTHAGHVLAV
AGGLAALKVYLEEGLFERAREIEGWLRDGLGELAERHPSIGDVRGMGAQFGIELVRDRETREPLVEWHHPAGSAPMRAFY
GELLKRGVHAYGRYNVVIVTPPLVISRTELDEGLDALDAALTVLEAAR
>Mature_448_residues
MDLSIHGESNPALASSFRKVLVPWAVQGGLNPPVITHAQGCYFYDANGKRYLDLTSGYVAVSLGHGHPKVVEAIQAQAAR
MCWVASSYFNDVRAEYAELLNSVSPWPDGLRVHFTCGGAEANDDAVKIARLVTRRPKVLTAYRSYHGSTLGASAMTGVDR
WRDPFPALPGMVKFFAPYPYRSPFHTSEPAEETRRALDHLARVLSHEGAQNVAAILMEPMTGSSGVVVYPPGYLAGVRDL
CDRHGILLIFDEVMTGFGRTGALFCAERVGVLPDLISFAKGASSSYTPLGGVLVREGVARHFDTELFDVGHTHAGHVLAV
AGGLAALKVYLEEGLFERAREIEGWLRDGLGELAERHPSIGDVRGMGAQFGIELVRDRETREPLVEWHHPAGSAPMRAFY
GELLKRGVHAYGRYNVVIVTPPLVISRTELDEGLDALDAALTVLEAAR

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=465, Percent_Identity=29.6774193548387, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI4557809, Length=421, Percent_Identity=30.6413301662708, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI24119277, Length=425, Percent_Identity=31.0588235294118, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI37574042, Length=430, Percent_Identity=29.7674418604651, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI226442705, Length=430, Percent_Identity=29.0697674418605, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=29.1457286432161, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI284507298, Length=335, Percent_Identity=31.044776119403, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI1789016, Length=431, Percent_Identity=34.1067285382831, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787560, Length=409, Percent_Identity=34.4743276283619, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI145693181, Length=410, Percent_Identity=30.4878048780488, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1788044, Length=439, Percent_Identity=28.7015945330296, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789759, Length=444, Percent_Identity=26.5765765765766, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1786991, Length=425, Percent_Identity=29.1764705882353, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786349, Length=361, Percent_Identity=29.6398891966759, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32564660, Length=430, Percent_Identity=32.3255813953488, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI25144271, Length=420, Percent_Identity=27.8571428571429, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=434, Percent_Identity=30.6451612903226, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25144274, Length=306, Percent_Identity=27.4509803921569, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=485, Percent_Identity=24.1237113402062, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=29.375, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=426, Percent_Identity=30.5164319248826, Blast_Score=155, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6324432, Length=427, Percent_Identity=25.7611241217799, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324386, Length=426, Percent_Identity=24.1784037558685, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28574759, Length=457, Percent_Identity=33.2603938730853, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI161085790, Length=456, Percent_Identity=33.1140350877193, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI21357415, Length=415, Percent_Identity=29.1566265060241, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356575, Length=434, Percent_Identity=30.6451612903226, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281366494, Length=378, Percent_Identity=23.5449735449735, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667139, Length=378, Percent_Identity=23.5449735449735, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667143, Length=378, Percent_Identity=23.5449735449735, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 48711; Mature: 48711

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSIHGESNPALASSFRKVLVPWAVQGGLNPPVITHAQGCYFYDANGKRYLDLTSGYVA
CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEECCCCCEEEEEECCEEE
VSLGHGHPKVVEAIQAQAARMCWVASSYFNDVRAEYAELLNSVSPWPDGLRVHFTCGGAE
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ANDDAVKIARLVTRRPKVLTAYRSYHGSTLGASAMTGVDRWRDPFPALPGMVKFFAPYPY
CCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
RSPFHTSEPAEETRRALDHLARVLSHEGAQNVAAILMEPMTGSSGVVVYPPGYLAGVRDL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHH
CDRHGILLIFDEVMTGFGRTGALFCAERVGVLPDLISFAKGASSSYTPLGGVLVREGVAR
HHCCCEEEEEHHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
HFDTELFDVGHTHAGHVLAVAGGLAALKVYLEEGLFERAREIEGWLRDGLGELAERHPSI
HHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDVRGMGAQFGIELVRDRETREPLVEWHHPAGSAPMRAFYGELLKRGVHAYGRYNVVIVT
CHHHCCCHHHHHHHHHCCCHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
PPLVISRTELDEGLDALDAALTVLEAAR
CCEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLSIHGESNPALASSFRKVLVPWAVQGGLNPPVITHAQGCYFYDANGKRYLDLTSGYVA
CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEECCCCCEEEEEECCEEE
VSLGHGHPKVVEAIQAQAARMCWVASSYFNDVRAEYAELLNSVSPWPDGLRVHFTCGGAE
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ANDDAVKIARLVTRRPKVLTAYRSYHGSTLGASAMTGVDRWRDPFPALPGMVKFFAPYPY
CCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
RSPFHTSEPAEETRRALDHLARVLSHEGAQNVAAILMEPMTGSSGVVVYPPGYLAGVRDL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHH
CDRHGILLIFDEVMTGFGRTGALFCAERVGVLPDLISFAKGASSSYTPLGGVLVREGVAR
HHCCCEEEEEHHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
HFDTELFDVGHTHAGHVLAVAGGLAALKVYLEEGLFERAREIEGWLRDGLGELAERHPSI
HHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDVRGMGAQFGIELVRDRETREPLVEWHHPAGSAPMRAFYGELLKRGVHAYGRYNVVIVT
CHHHCCCHHHHHHHHHCCCHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
PPLVISRTELDEGLDALDAALTVLEAAR
CCEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]