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The map label for this gene is acdA [H]

Identifier: 103488554

GI number: 103488554

Start: 3229508

End: 3230626

Strand: Direct

Name: acdA [H]

Synonym: Sala_3078

Alternate gene names: 103488554

Gene position: 3229508-3230626 (Clockwise)

Preceding gene: 103488553

Following gene: 103488555

Centisome position: 96.54

GC content: 67.47

Gene sequence:

>1119_bases
ATGCCGCTCTATCACAATGACGACCAGGCGATGCTCAAGGACAGCGTCGCGCCCTTCGTCGCCGAACAGGCGCCGGTGTC
GCACCTGCGCAAGCTGCGCGACAGCGCCGACGCCACCGGCTTCTCGCGCGACCTCTGGGCGCAGTTCACCGAAATGGGCC
TGCCGGGGATGCTCGTTGCCGAGGAGCATGGCGGGCTCGGCATGGGGCATATGGAGGCGGGCATCGTGCTCGAGGAAATC
GGCCGCAACCTGACCCCCTCACCCTTCCTGTCGACCAGCGTCGGCGCGGTCGCCGCGCTGGCCAAGGCAGGCGGAACGCA
GGCCGGCCGCTGGCTCCCCGCCATCGCCAGCGGTGAAGCGATCGTCGCGCTCGCGATCGACGAAGGCGCCAAGCACCGCC
CCGACCGCATCGCCACCACCGCGACGCGCGCCGGAAACGGCTTTCGGTTGGACGGCAAAAAGAGCTTCGTCCTCCACGGC
CATGTCGCCGACATGAGCATCGTCGCGGCAAAGACCGACGGCGGCATCACCCTGTTCGCGGTGCCGAAGGACGCGAAAGG
CCTGACCGCCGATCCGCGCCGCCTCGTCGATTCGAGCCTCGCGAGCCATGTCACCCTCGACGGGGTCGAGGTCGATGCCG
ACGCGGTGATCGGCGAGGTCGATGCCGGCGGCGAGATTCTCGACGCGCTGCTCGCAGCCACCCGCACCGGGGCGGCTGCC
GAAATGGTCGGGGTGGGGCAGGGGGCGATGGACATGACCGTCGCCTATCTCAAGGAACGCAAGCAGTTCGGGCGTCTGAT
CGGCGAGTTTCAGGGCCTCCAGCACCGCGCCGCGCATCTCTATGGCGAGATGGAAGTCGCGCGCGCGGCGGTGATGAAGG
CGCAGCAATTGCTCGACGAGGGCAGCGAAGGCGCGAAGCTGATGGTCTCGGTCGCGAAAGCCAAGGCCGGGCGCGCCGCC
AACCTCGCGGTGCGCGAAGGCGTGCAGATGCACGGCGGCATCGGCATGACCGACGAATATGACATCGGGCTCTATATGAA
ACGCGACCGTGCGCTGGCGGAATATATGGGCGATGTGCATTATCACATCGACCAGGTCGCGCGGATGAACGGCTACTAA

Upstream 100 bases:

>100_bases
CGCCCCAGCGAAAGCTGGGGCCGCTATCGGGACAGAGCGGTGTTGGCCGCCAACGATCCCAGCTTTCGCTGGGATGACGA
CAAGAGAGATTGGGACAGAT

Downstream 100 bases:

>100_bases
GGTGCAATCACGCCCTCCCCTTCAGGGGAGGGCAGCGAGACTTGCCAGCTTGCTGGCTTAGTCGCAGCGGGTGGGGGCCA
GAGGCCTTGCGCTACGCCGC

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MPLYHNDDQAMLKDSVAPFVAEQAPVSHLRKLRDSADATGFSRDLWAQFTEMGLPGMLVAEEHGGLGMGHMEAGIVLEEI
GRNLTPSPFLSTSVGAVAALAKAGGTQAGRWLPAIASGEAIVALAIDEGAKHRPDRIATTATRAGNGFRLDGKKSFVLHG
HVADMSIVAAKTDGGITLFAVPKDAKGLTADPRRLVDSSLASHVTLDGVEVDADAVIGEVDAGGEILDALLAATRTGAAA
EMVGVGQGAMDMTVAYLKERKQFGRLIGEFQGLQHRAAHLYGEMEVARAAVMKAQQLLDEGSEGAKLMVSVAKAKAGRAA
NLAVREGVQMHGGIGMTDEYDIGLYMKRDRALAEYMGDVHYHIDQVARMNGY

Sequences:

>Translated_372_residues
MPLYHNDDQAMLKDSVAPFVAEQAPVSHLRKLRDSADATGFSRDLWAQFTEMGLPGMLVAEEHGGLGMGHMEAGIVLEEI
GRNLTPSPFLSTSVGAVAALAKAGGTQAGRWLPAIASGEAIVALAIDEGAKHRPDRIATTATRAGNGFRLDGKKSFVLHG
HVADMSIVAAKTDGGITLFAVPKDAKGLTADPRRLVDSSLASHVTLDGVEVDADAVIGEVDAGGEILDALLAATRTGAAA
EMVGVGQGAMDMTVAYLKERKQFGRLIGEFQGLQHRAAHLYGEMEVARAAVMKAQQLLDEGSEGAKLMVSVAKAKAGRAA
NLAVREGVQMHGGIGMTDEYDIGLYMKRDRALAEYMGDVHYHIDQVARMNGY
>Mature_371_residues
PLYHNDDQAMLKDSVAPFVAEQAPVSHLRKLRDSADATGFSRDLWAQFTEMGLPGMLVAEEHGGLGMGHMEAGIVLEEIG
RNLTPSPFLSTSVGAVAALAKAGGTQAGRWLPAIASGEAIVALAIDEGAKHRPDRIATTATRAGNGFRLDGKKSFVLHGH
VADMSIVAAKTDGGITLFAVPKDAKGLTADPRRLVDSSLASHVTLDGVEVDADAVIGEVDAGGEILDALLAATRTGAAAE
MVGVGQGAMDMTVAYLKERKQFGRLIGEFQGLQHRAAHLYGEMEVARAAVMKAQQLLDEGSEGAKLMVSVAKAKAGRAAN
LAVREGVQMHGGIGMTDEYDIGLYMKRDRALAEYMGDVHYHIDQVARMNGY

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=27.7333333333333, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI226958412, Length=367, Percent_Identity=29.700272479564, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI226958414, Length=364, Percent_Identity=29.9450549450549, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI4501857, Length=346, Percent_Identity=29.1907514450867, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4557233, Length=302, Percent_Identity=27.8145695364238, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI187960098, Length=332, Percent_Identity=26.8072289156627, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4557231, Length=332, Percent_Identity=26.8072289156627, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI76496475, Length=313, Percent_Identity=26.8370607028754, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4557235, Length=313, Percent_Identity=26.8370607028754, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI21361497, Length=344, Percent_Identity=25.2906976744186, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4503943, Length=367, Percent_Identity=24.2506811989101, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI7669494, Length=347, Percent_Identity=24.207492795389, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI7656849, Length=320, Percent_Identity=23.4375, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87081958, Length=357, Percent_Identity=23.249299719888, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786223, Length=358, Percent_Identity=24.0223463687151, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=335, Percent_Identity=31.6417910447761, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17508101, Length=350, Percent_Identity=28.5714285714286, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71990804, Length=270, Percent_Identity=31.8518518518519, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=366, Percent_Identity=27.5956284153005, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=32.4675324675325, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=24.4094488188976, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=347, Percent_Identity=24.207492795389, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=325, Percent_Identity=24, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=24.3697478991597, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=25.3263707571802, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=283, Percent_Identity=28.2685512367491, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534353, Length=343, Percent_Identity=24.7813411078717, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=333, Percent_Identity=23.4234234234234, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=29.2105263157895, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355753, Length=366, Percent_Identity=30.0546448087432, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21356377, Length=304, Percent_Identity=28.2894736842105, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646207, Length=318, Percent_Identity=27.6729559748428, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24660351, Length=321, Percent_Identity=26.1682242990654, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363737, Length=313, Percent_Identity=23.3226837060703, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920834, Length=336, Percent_Identity=23.8095238095238, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 39271; Mature: 39140

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLYHNDDQAMLKDSVAPFVAEQAPVSHLRKLRDSADATGFSRDLWAQFTEMGLPGMLVA
CCCEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEE
EEHGGLGMGHMEAGIVLEEIGRNLTPSPFLSTSVGAVAALAKAGGTQAGRWLPAIASGEA
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCE
IVALAIDEGAKHRPDRIATTATRAGNGFRLDGKKSFVLHGHVADMSIVAAKTDGGITLFA
EEEEEECCCCCCCCCHHHHHHHCCCCCEEECCCCEEEEEEEECCEEEEEEECCCCEEEEE
VPKDAKGLTADPRRLVDSSLASHVTLDGVEVDADAVIGEVDAGGEILDALLAATRTGAAA
ECCCCCCCCCCHHHHHHHHHHHHEEECCEEECHHHEEECCCCCHHHHHHHHHHHCCCCHH
EMVGVGQGAMDMTVAYLKERKQFGRLIGEFQGLQHRAAHLYGEMEVARAAVMKAQQLLDE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSEGAKLMVSVAKAKAGRAANLAVREGVQMHGGIGMTDEYDIGLYMKRDRALAEYMGDVH
CCCCCEEHHHHHHHCCCCHHHHHHHCCCHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
YHIDQVARMNGY
HHHHHHHHHCCC
>Mature Secondary Structure 
PLYHNDDQAMLKDSVAPFVAEQAPVSHLRKLRDSADATGFSRDLWAQFTEMGLPGMLVA
CCEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEE
EEHGGLGMGHMEAGIVLEEIGRNLTPSPFLSTSVGAVAALAKAGGTQAGRWLPAIASGEA
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCE
IVALAIDEGAKHRPDRIATTATRAGNGFRLDGKKSFVLHGHVADMSIVAAKTDGGITLFA
EEEEEECCCCCCCCCHHHHHHHCCCCCEEECCCCEEEEEEEECCEEEEEEECCCCEEEEE
VPKDAKGLTADPRRLVDSSLASHVTLDGVEVDADAVIGEVDAGGEILDALLAATRTGAAA
ECCCCCCCCCCHHHHHHHHHHHHEEECCEEECHHHEEECCCCCHHHHHHHHHHHCCCCHH
EMVGVGQGAMDMTVAYLKERKQFGRLIGEFQGLQHRAAHLYGEMEVARAAVMKAQQLLDE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSEGAKLMVSVAKAKAGRAANLAVREGVQMHGGIGMTDEYDIGLYMKRDRALAEYMGDVH
CCCCCEEHHHHHHHCCCCHHHHHHHCCCHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
YHIDQVARMNGY
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]