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The map label for this gene is pdhB [H]

Identifier: 103488439

GI number: 103488439

Start: 3104785

End: 3106986

Strand: Reverse

Name: pdhB [H]

Synonym: Sala_2962

Alternate gene names: 103488439

Gene position: 3106986-3104785 (Counterclockwise)

Preceding gene: 103488448

Following gene: 103488438

Centisome position: 92.88

GC content: 66.62

Gene sequence:

>2202_bases
GTGGACGCGGCTGAGGCGGTACATGAAAAATTCCTTGGCGCGCTGGCCGAAGGGCGATTGCCCGGCCGCGCCGACGCGCC
CGACCCCGGCGCGATCGGCCTGTCGCGCAGCGAGGCCACCGATATTTTCCTGTCGCAACTCACCAGCCGCCAGATGGACC
GGCTGTCGCGCCACCTGCAGGCGCGCGGCGAAGGATTCTATACGATCGGCTCGTCGGGGCACGAAGGCAATGCCGCGGTC
GCCGCGGCGCTGCGCGCCACCGACATGGCGTTTCTCCACTATCGTTCGAACGCCTTTCAGCTTCACCGCGCGCGGCAGGT
GCCGGGACAGACGCCGACGTGGGACATGCTCTTGAGCTTTGCGGCGTCGAGCGAAGACCCGATTTCGGGCGGCCGGCACA
AGGTCATCGGGTCGAAGCCGCTCGCTATCCCGCCACAGACCTCGACGATCGCCTCGCACCTGCCCAAGGCGGTGGGCGCC
GCCTTTTCGATCGGCATCGCGCGCCGCCTTGGCATGACCGGACTGCCGCTTCCCGACGACGCGGTCGTGCTCGCGAGCTT
CGGCGATGCGTCGGCGAACCATTCGACCGCACAGGGGGCGTTCAACACCGCGGGTTGGGCAGCCTACCAAGGGTCTCCCA
TGCCGCTGGTCTTTCTGTGCGAGGACAATGGCATCGGCATTTCGACGCGCACGCCGGCGGGATGGATCGAGGCGCAGTTC
CGCCATCGCGCCGGGCTGCACTATATCCAGTGCGACGGCACGGACCTGGCCGCGGCGTACAAGGGCGCGAAGGAGGCGGC
CGATTATGCACGCCGCACGCGGCGGCCCGTTTTCCTGCACATGGCCACGGTGCGGCTGTACGGTCATGCCGGATCGGACG
TGCAGGGCGCCTATCTTCCCAAGGCGCTGATCGAAGCCGACGAGGCGCGCGATCCGCTGCTGAAGGGCGCCGCGCTGATG
ATCGAACAGGGGTGGATGAGCGCGGCGGACGTCGCCGATGCCTATCAGGAGATCGGCGCGACGCTGGCACGGCAGGCCGA
GGCGGCGATCCGGCGGCCCAAGATCACCACCGCGGCGGCGGTGATGGCGAGCCTGATCCCGCCGAAACGTGCGATCGCGC
GCGCCAACAGCCCGTCAGACGACGAGCGCAAGGCGATGTTCGGCAACGACTGGGGCCAGATGGACAAGCCGATGCACATG
GCGCGGCTTTTGAGCTGGGCGCTCGCCGACCTGATGCTCGCACATCGAGAGATCGTCGTCGCGGGCGAGGATGTCGGACC
GAAGGGCGGCGTCTATAATGTCACCGCCAAGCTGCACCAGCGCTTCGGATCGGCGCGCGTCATCAACACGCTGCTCGACG
AACAGGCGATCCTGGGGCTCGCGATCGGCATGGCGCACAACGGCTTTGTCCCGATGCCCGAAATCCAGTTCCTCGCCTAT
GTCCACAATGCCGAGGACCAGATTCGCGGCGAGGCGGCGACCCTGAGCTTCTTCTCGAACGGACAGTACACCAACCCGAT
GGTGATCCGCATCGCGGGGCTGGGCTATCAAAAGGGCTTTGGCGGCCATTTCCACAACGACAACAGCCTCGCCGTGTTCC
GCGACATTCCGGGCATCATCCTGGCGGTGCCGTCGAACGGGCGCGACGCGGTGCAAATGTTGCGCGAATGCGTGCGGCTG
GCGCGCGAGGAGCAGCGCGTCGTCGTGTTCGTCGAACCGATCGCGCTCTATATGACGCGCGACCTGCATGAAGAGGGCGA
TGGGCTGTGGACCAGCATCTATGAGGCGCCCGGCGAAGGCACGCCGATCCGGTTCGGCGATGTCGGCGTCCATGGCGACG
GCACCGACCTCGCGATCGTAACCTACGGCAACGGATATTATCTCTCGCGGCAGGCCGAAAAACTGCTCGCCGAAGATGGC
GTCAAGGCGCGCGTGATCGACCTGCGCTGGCTGGGACCCGTCGATACCGACAAGCTGGTCGCCGCGGTCGGCGGTGCGAA
GCGCATCCTGATCGTCGACGAATGCCGCATCACCGGTTCGCAGAGCGAGGCGCTGATGGCATTGTTCGTTGAACAGACGC
CGGACAAAAAAATCGCGCGCATCGCCGCCGACGACAGCTTCATCCCGCTGGGCAGGGCGGCAACGCTGACCCTGCCGAGC
CGCGAGGGCATCATTGCCGCGGCAAGGGAGCTCCTGGCATGA

Upstream 100 bases:

>100_bases
GCAAGAGATGCTTGCGCGCCGGACCGCCCCGTTCTAGCGCGCGGCAAAATCGGCCGGGTCGTTGCAATGGCAACCAGCGG
CCGGGCGACAGGAGAGACAG

Downstream 100 bases:

>100_bases
GCGCCCGCAAAACCGCGATCGTCGTCGCGCCCGGCCGCGGCACTTATGGCAAGGGCGAGCTGGGCAGCATCGCGCGGCTG
CATGGCGCGCGATTTGCCGA

Product: transketolase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 733

Protein sequence:

>733_residues
MDAAEAVHEKFLGALAEGRLPGRADAPDPGAIGLSRSEATDIFLSQLTSRQMDRLSRHLQARGEGFYTIGSSGHEGNAAV
AAALRATDMAFLHYRSNAFQLHRARQVPGQTPTWDMLLSFAASSEDPISGGRHKVIGSKPLAIPPQTSTIASHLPKAVGA
AFSIGIARRLGMTGLPLPDDAVVLASFGDASANHSTAQGAFNTAGWAAYQGSPMPLVFLCEDNGIGISTRTPAGWIEAQF
RHRAGLHYIQCDGTDLAAAYKGAKEAADYARRTRRPVFLHMATVRLYGHAGSDVQGAYLPKALIEADEARDPLLKGAALM
IEQGWMSAADVADAYQEIGATLARQAEAAIRRPKITTAAAVMASLIPPKRAIARANSPSDDERKAMFGNDWGQMDKPMHM
ARLLSWALADLMLAHREIVVAGEDVGPKGGVYNVTAKLHQRFGSARVINTLLDEQAILGLAIGMAHNGFVPMPEIQFLAY
VHNAEDQIRGEAATLSFFSNGQYTNPMVIRIAGLGYQKGFGGHFHNDNSLAVFRDIPGIILAVPSNGRDAVQMLRECVRL
AREEQRVVVFVEPIALYMTRDLHEEGDGLWTSIYEAPGEGTPIRFGDVGVHGDGTDLAIVTYGNGYYLSRQAEKLLAEDG
VKARVIDLRWLGPVDTDKLVAAVGGAKRILIVDECRITGSQSEALMALFVEQTPDKKIARIAADDSFIPLGRAATLTLPS
REGIIAAARELLA

Sequences:

>Translated_733_residues
MDAAEAVHEKFLGALAEGRLPGRADAPDPGAIGLSRSEATDIFLSQLTSRQMDRLSRHLQARGEGFYTIGSSGHEGNAAV
AAALRATDMAFLHYRSNAFQLHRARQVPGQTPTWDMLLSFAASSEDPISGGRHKVIGSKPLAIPPQTSTIASHLPKAVGA
AFSIGIARRLGMTGLPLPDDAVVLASFGDASANHSTAQGAFNTAGWAAYQGSPMPLVFLCEDNGIGISTRTPAGWIEAQF
RHRAGLHYIQCDGTDLAAAYKGAKEAADYARRTRRPVFLHMATVRLYGHAGSDVQGAYLPKALIEADEARDPLLKGAALM
IEQGWMSAADVADAYQEIGATLARQAEAAIRRPKITTAAAVMASLIPPKRAIARANSPSDDERKAMFGNDWGQMDKPMHM
ARLLSWALADLMLAHREIVVAGEDVGPKGGVYNVTAKLHQRFGSARVINTLLDEQAILGLAIGMAHNGFVPMPEIQFLAY
VHNAEDQIRGEAATLSFFSNGQYTNPMVIRIAGLGYQKGFGGHFHNDNSLAVFRDIPGIILAVPSNGRDAVQMLRECVRL
AREEQRVVVFVEPIALYMTRDLHEEGDGLWTSIYEAPGEGTPIRFGDVGVHGDGTDLAIVTYGNGYYLSRQAEKLLAEDG
VKARVIDLRWLGPVDTDKLVAAVGGAKRILIVDECRITGSQSEALMALFVEQTPDKKIARIAADDSFIPLGRAATLTLPS
REGIIAAARELLA
>Mature_733_residues
MDAAEAVHEKFLGALAEGRLPGRADAPDPGAIGLSRSEATDIFLSQLTSRQMDRLSRHLQARGEGFYTIGSSGHEGNAAV
AAALRATDMAFLHYRSNAFQLHRARQVPGQTPTWDMLLSFAASSEDPISGGRHKVIGSKPLAIPPQTSTIASHLPKAVGA
AFSIGIARRLGMTGLPLPDDAVVLASFGDASANHSTAQGAFNTAGWAAYQGSPMPLVFLCEDNGIGISTRTPAGWIEAQF
RHRAGLHYIQCDGTDLAAAYKGAKEAADYARRTRRPVFLHMATVRLYGHAGSDVQGAYLPKALIEADEARDPLLKGAALM
IEQGWMSAADVADAYQEIGATLARQAEAAIRRPKITTAAAVMASLIPPKRAIARANSPSDDERKAMFGNDWGQMDKPMHM
ARLLSWALADLMLAHREIVVAGEDVGPKGGVYNVTAKLHQRFGSARVINTLLDEQAILGLAIGMAHNGFVPMPEIQFLAY
VHNAEDQIRGEAATLSFFSNGQYTNPMVIRIAGLGYQKGFGGHFHNDNSLAVFRDIPGIILAVPSNGRDAVQMLRECVRL
AREEQRVVVFVEPIALYMTRDLHEEGDGLWTSIYEAPGEGTPIRFGDVGVHGDGTDLAIVTYGNGYYLSRQAEKLLAEDG
VKARVIDLRWLGPVDTDKLVAAVGGAKRILIVDECRITGSQSEALMALFVEQTPDKKIARIAADDSFIPLGRAATLTLPS
REGIIAAARELLA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=345, Percent_Identity=29.2753623188406, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI34101272, Length=345, Percent_Identity=29.2753623188406, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI156564403, Length=262, Percent_Identity=24.4274809160305, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI11386135, Length=328, Percent_Identity=24.6951219512195, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI258645172, Length=332, Percent_Identity=24.6987951807229, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI291084858, Length=262, Percent_Identity=22.9007633587786, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI4885543, Length=176, Percent_Identity=28.9772727272727, Blast_Score=73, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86563357, Length=310, Percent_Identity=27.741935483871, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI86563355, Length=310, Percent_Identity=27.741935483871, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538422, Length=341, Percent_Identity=25.8064516129032, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17506935, Length=284, Percent_Identity=29.9295774647887, Blast_Score=91, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319698, Length=346, Percent_Identity=27.1676300578035, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI160714832, Length=319, Percent_Identity=27.2727272727273, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI160714828, Length=319, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355903, Length=338, Percent_Identity=24.8520710059172, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21358145, Length=344, Percent_Identity=26.7441860465116, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24650940, Length=344, Percent_Identity=26.7441860465116, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 78707; Mature: 78707

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAEAVHEKFLGALAEGRLPGRADAPDPGAIGLSRSEATDIFLSQLTSRQMDRLSRHLQ
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARGEGFYTIGSSGHEGNAAVAAALRATDMAFLHYRSNAFQLHRARQVPGQTPTWDMLLSF
HCCCEEEEECCCCCCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
AASSEDPISGGRHKVIGSKPLAIPPQTSTIASHLPKAVGAAFSIGIARRLGMTGLPLPDD
HCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AVVLASFGDASANHSTAQGAFNTAGWAAYQGSPMPLVFLCEDNGIGISTRTPAGWIEAQF
CEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCEEEECCCCCHHHHHHH
RHRAGLHYIQCDGTDLAAAYKGAKEAADYARRTRRPVFLHMATVRLYGHAGSDVQGAYLP
HHHCCCEEEEECCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCC
KALIEADEARDPLLKGAALMIEQGWMSAADVADAYQEIGATLARQAEAAIRRPKITTAAA
HHHHCCHHHCCHHHHCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VMASLIPPKRAIARANSPSDDERKAMFGNDWGQMDKPMHMARLLSWALADLMLAHREIVV
HHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
AGEDVGPKGGVYNVTAKLHQRFGSARVINTLLDEQAILGLAIGMAHNGFVPMPEIQFLAY
ECCCCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEE
VHNAEDQIRGEAATLSFFSNGQYTNPMVIRIAGLGYQKGFGGHFHNDNSLAVFRDIPGII
EECCHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEE
LAVPSNGRDAVQMLRECVRLAREEQRVVVFVEPIALYMTRDLHEEGDGLWTSIYEAPGEG
EEECCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCEEEHHEECCCCC
TPIRFGDVGVHGDGTDLAIVTYGNGYYLSRQAEKLLAEDGVKARVIDLRWLGPVDTDKLV
CCEEECCEEECCCCCCEEEEEECCCEEECHHHHHHHHHCCCEEEEEEEEECCCCCHHHHH
AAVGGAKRILIVDECRITGSQSEALMALFVEQTPDKKIARIAADDSFIPLGRAATLTLPS
HHCCCCEEEEEEEECEECCCCCCEEEEEEECCCCCHHHHEEECCCCCCCCCCEEEEECCC
REGIIAAARELLA
CCCHHHHHHHHCC
>Mature Secondary Structure
MDAAEAVHEKFLGALAEGRLPGRADAPDPGAIGLSRSEATDIFLSQLTSRQMDRLSRHLQ
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARGEGFYTIGSSGHEGNAAVAAALRATDMAFLHYRSNAFQLHRARQVPGQTPTWDMLLSF
HCCCEEEEECCCCCCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
AASSEDPISGGRHKVIGSKPLAIPPQTSTIASHLPKAVGAAFSIGIARRLGMTGLPLPDD
HCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AVVLASFGDASANHSTAQGAFNTAGWAAYQGSPMPLVFLCEDNGIGISTRTPAGWIEAQF
CEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCEEEECCCCCHHHHHHH
RHRAGLHYIQCDGTDLAAAYKGAKEAADYARRTRRPVFLHMATVRLYGHAGSDVQGAYLP
HHHCCCEEEEECCCCHHHHHCCHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCC
KALIEADEARDPLLKGAALMIEQGWMSAADVADAYQEIGATLARQAEAAIRRPKITTAAA
HHHHCCHHHCCHHHHCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VMASLIPPKRAIARANSPSDDERKAMFGNDWGQMDKPMHMARLLSWALADLMLAHREIVV
HHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
AGEDVGPKGGVYNVTAKLHQRFGSARVINTLLDEQAILGLAIGMAHNGFVPMPEIQFLAY
ECCCCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEE
VHNAEDQIRGEAATLSFFSNGQYTNPMVIRIAGLGYQKGFGGHFHNDNSLAVFRDIPGII
EECCHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEE
LAVPSNGRDAVQMLRECVRLAREEQRVVVFVEPIALYMTRDLHEEGDGLWTSIYEAPGEG
EEECCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCEEEHHEECCCCC
TPIRFGDVGVHGDGTDLAIVTYGNGYYLSRQAEKLLAEDGVKARVIDLRWLGPVDTDKLV
CCEEECCEEECCCCCCEEEEEECCCEEECHHHHHHHHHCCCEEEEEEEEECCCCCHHHHH
AAVGGAKRILIVDECRITGSQSEALMALFVEQTPDKKIARIAADDSFIPLGRAATLTLPS
HHCCCCEEEEEEEECEECCCCCCEEEEEEECCCCCHHHHEEECCCCCCCCCCEEEEECCC
REGIIAAARELLA
CCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA