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The map label for this gene is tldD [H]

Identifier: 103487800

GI number: 103487800

Start: 2447265

End: 2448707

Strand: Direct

Name: tldD [H]

Synonym: Sala_2319

Alternate gene names: 103487800

Gene position: 2447265-2448707 (Clockwise)

Preceding gene: 103487799

Following gene: 103487801

Centisome position: 73.16

GC content: 68.05

Gene sequence:

>1443_bases
ATGACAAGCCCCACCGATCCCCGCCGCTTCCTCTATCGCGCCGACGCGCTCGACCCCGATCTGGCGCAAAAGCTCGCGTG
CGAGGCCTTGGCAAAGGCCGACGACGGCGAACTTTACCTGCAATATCGCGCGACCGAGAGCTTCGGCTTCGACGACGGGC
GGCTGAAAACCGCCGACTATTCGACCGATGCGGGTTTCGGCCTGCGCGCCGTGTCGGGCGAGATGACGGGCTTTGCACAC
GCGAGCGACATCAGCGCCGACGCGATCCGCCGCGCGGCCGAGACGCTCGCGCTGCTCGATCCGGCGAAACAGGCGCACGC
CGCACCGCCGCCGCGCACCAACCGCCATCTTTATGACGAGGCGAACCCGCTCGACCTGGTCCCCTTCGCAAAGAAGGTCG
CGCTGTGCCAGCAAGTCGACGCCGCCGCGCGCGCACGCGATCCGCGCGTCGTGCAGGTTTCGGTTGCGCTCGCGGGCAGT
TGGTCGGTCGTCGAGATCGTCCGCGCCGACGGCTTCCTCGCGACCGACATCCGCCCGCTCGTCCGCCTCAACGTCTCGAT
CGTGGTCGAGGAGAATGGGCGGCGCGAGAGCGGCTATTTCGGCCTCGGCGGCCGTTACATGTACGATCATCTGTTCGAGG
AAGCGCAGTGGAACCGCGCGATCGACGAGGCGCTGAGCCAGGCGCTCGTCAACCTCCGCGCCGTCGATGCCCCCGCGGGC
GAGTTTACCGTGCTGCTCGGTCCCGGCTGGCCGGGCGTGCTGCTGCACGAAGCCGTCGGCCACGGCCTCGAGGGCGACTT
CAACCGCAAGGGCACCAGCGCCTTTTCGGGCCGCATCGGCGAGCGCGTCGCCGCGCCCGGTGTCACCGTGGTCGACGACG
GCGCGATGGAAAGTCCCGTCGGCGGTGGCCGCCGCGGCTCGCTCAGCATCGACGACGAAGGCACCCCGACGGGCGAAACC
GTGCTGATCGAGGACGGCATCCTGAAGGGCTATATGCAGGACCGGCTCAACGCGCGACTGATGGGCGTCGAACCCACGGG
CAACGGCCGCCGCGAGAGCTTCGCACACGCGCCGATGCCGCGGATGACCAACACCTTCATGCGCGGCGGCCGTGACGATC
CCGCCGAGCTTCTCTCGCGTGTCAAGAACGGCATTTTCGCGAAGAGCTTCGGCGGCGGACAGGTCGACATCGTATCGGGA
AAATTCGTGTTCAGCTGCACCGAGGCGTACAAGATCGAGAATGGCAAGCTGGGCGATTCGATCAAGGGCGCAACCTTGAT
CGGCGACGGGCCGAGCGTGCTGACCAAGGTCACCGGCATCGGCAACGACATGGCGATCGACGAAGGCATCGGCGTATGCG
GCAAGGCGGGGCAGAGCGTCCCCGCAGGCGTCGGCCAGCCGACCTTGCTGGTGAGCGGCCTGACCGTGGGCGGGACGGCC
TAG

Upstream 100 bases:

>100_bases
TTGCGACCGCCGCTTCGTGCTGATCGGCGGCGTCGCGGATAAGGCATAGCCCGGACGAACGGCCTTTGCGTCGGCGGCCC
CGCGTCCCTATATCGGTTCG

Downstream 100 bases:

>100_bases
CGCGCCCCGTCATTGCGAGGAGCGAAGCGACGAAGCAATCTCCAGCTACCAGCCTTGCGTGACGGCGATGGCTGGAGATC
GCGTCGCTTCGCTCGCAATG

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTSPTDPRRFLYRADALDPDLAQKLACEALAKADDGELYLQYRATESFGFDDGRLKTADYSTDAGFGLRAVSGEMTGFAH
ASDISADAIRRAAETLALLDPAKQAHAAPPPRTNRHLYDEANPLDLVPFAKKVALCQQVDAAARARDPRVVQVSVALAGS
WSVVEIVRADGFLATDIRPLVRLNVSIVVEENGRRESGYFGLGGRYMYDHLFEEAQWNRAIDEALSQALVNLRAVDAPAG
EFTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVAAPGVTVVDDGAMESPVGGGRRGSLSIDDEGTPTGET
VLIEDGILKGYMQDRLNARLMGVEPTGNGRRESFAHAPMPRMTNTFMRGGRDDPAELLSRVKNGIFAKSFGGGQVDIVSG
KFVFSCTEAYKIENGKLGDSIKGATLIGDGPSVLTKVTGIGNDMAIDEGIGVCGKAGQSVPAGVGQPTLLVSGLTVGGTA

Sequences:

>Translated_480_residues
MTSPTDPRRFLYRADALDPDLAQKLACEALAKADDGELYLQYRATESFGFDDGRLKTADYSTDAGFGLRAVSGEMTGFAH
ASDISADAIRRAAETLALLDPAKQAHAAPPPRTNRHLYDEANPLDLVPFAKKVALCQQVDAAARARDPRVVQVSVALAGS
WSVVEIVRADGFLATDIRPLVRLNVSIVVEENGRRESGYFGLGGRYMYDHLFEEAQWNRAIDEALSQALVNLRAVDAPAG
EFTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVAAPGVTVVDDGAMESPVGGGRRGSLSIDDEGTPTGET
VLIEDGILKGYMQDRLNARLMGVEPTGNGRRESFAHAPMPRMTNTFMRGGRDDPAELLSRVKNGIFAKSFGGGQVDIVSG
KFVFSCTEAYKIENGKLGDSIKGATLIGDGPSVLTKVTGIGNDMAIDEGIGVCGKAGQSVPAGVGQPTLLVSGLTVGGTA
>Mature_479_residues
TSPTDPRRFLYRADALDPDLAQKLACEALAKADDGELYLQYRATESFGFDDGRLKTADYSTDAGFGLRAVSGEMTGFAHA
SDISADAIRRAAETLALLDPAKQAHAAPPPRTNRHLYDEANPLDLVPFAKKVALCQQVDAAARARDPRVVQVSVALAGSW
SVVEIVRADGFLATDIRPLVRLNVSIVVEENGRRESGYFGLGGRYMYDHLFEEAQWNRAIDEALSQALVNLRAVDAPAGE
FTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVAAPGVTVVDDGAMESPVGGGRRGSLSIDDEGTPTGETV
LIEDGILKGYMQDRLNARLMGVEPTGNGRRESFAHAPMPRMTNTFMRGGRDDPAELLSRVKNGIFAKSFGGGQVDIVSGK
FVFSCTEAYKIENGKLGDSIKGATLIGDGPSVLTKVTGIGNDMAIDEGIGVCGKAGQSVPAGVGQPTLLVSGLTVGGTA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=467, Percent_Identity=52.4625267665953, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50750; Mature: 50619

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTDPRRFLYRADALDPDLAQKLACEALAKADDGELYLQYRATESFGFDDGRLKTADY
CCCCCCCHHHEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEECCC
STDAGFGLRAVSGEMTGFAHASDISADAIRRAAETLALLDPAKQAHAAPPPRTNRHLYDE
CCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCC
ANPLDLVPFAKKVALCQQVDAAARARDPRVVQVSVALAGSWSVVEIVRADGFLATDIRPL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCEEECCCCEE
VRLNVSIVVEENGRRESGYFGLGGRYMYDHLFEEAQWNRAIDEALSQALVNLRAVDAPAG
EEEEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
EFTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVAAPGVTVVDDGAMESPV
CEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHHHCCCCCEEEECCCCCCCC
GGGRRGSLSIDDEGTPTGETVLIEDGILKGYMQDRLNARLMGVEPTGNGRRESFAHAPMP
CCCCCCCEEECCCCCCCCCEEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
RMTNTFMRGGRDDPAELLSRVKNGIFAKSFGGGQVDIVSGKFVFSCTEAYKIENGKLGDS
HHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCCEEEEEECCEEEEEEHHEEECCCCCCCC
IKGATLIGDGPSVLTKVTGIGNDMAIDEGIGVCGKAGQSVPAGVGQPTLLVSGLTVGGTA
CCCCEEECCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
TSPTDPRRFLYRADALDPDLAQKLACEALAKADDGELYLQYRATESFGFDDGRLKTADY
CCCCCCHHHEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEECCC
STDAGFGLRAVSGEMTGFAHASDISADAIRRAAETLALLDPAKQAHAAPPPRTNRHLYDE
CCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCC
ANPLDLVPFAKKVALCQQVDAAARARDPRVVQVSVALAGSWSVVEIVRADGFLATDIRPL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCEEECCCCEE
VRLNVSIVVEENGRRESGYFGLGGRYMYDHLFEEAQWNRAIDEALSQALVNLRAVDAPAG
EEEEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
EFTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVAAPGVTVVDDGAMESPV
CEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHHHCCCCCEEEECCCCCCCC
GGGRRGSLSIDDEGTPTGETVLIEDGILKGYMQDRLNARLMGVEPTGNGRRESFAHAPMP
CCCCCCCEEECCCCCCCCCEEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCC
RMTNTFMRGGRDDPAELLSRVKNGIFAKSFGGGQVDIVSGKFVFSCTEAYKIENGKLGDS
HHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCCEEEEEECCEEEEEEHHEEECCCCCCCC
IKGATLIGDGPSVLTKVTGIGNDMAIDEGIGVCGKAGQSVPAGVGQPTLLVSGLTVGGTA
CCCCEEECCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]