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The map label for this gene is 103487793

Identifier: 103487793

GI number: 103487793

Start: 2439711

End: 2440970

Strand: Reverse

Name: 103487793

Synonym: Sala_2312

Alternate gene names: NA

Gene position: 2440970-2439711 (Counterclockwise)

Preceding gene: 103487796

Following gene: 103487787

Centisome position: 72.97

GC content: 65.95

Gene sequence:

>1260_bases
ATGAACAAAGCCTCCTTGCTCGTCAGCCTCGCCGCGCTCGCCCTTGTTTCCAGCCCCGTCGCCGCCCAGACCTCGCCCGA
GGCGGTGGCCGCGGCCGCGCTCAAGAAGGCGCCGGTGTTCGACGGGCATAATGACGTGCCCTGGGCGCTGCGCGCGCGCG
TCGATAACGTCATCAATGATTTCGATTTCGTCGACACGACCGATACCGCGACCGGGGACCGGATCGCGATGCACACCGAC
CTCACCCGGCTGCGCCGCGGGCATGTCGGCGCGCAATTCTGGTCGGTTTACGTTCCCTCGACCACCAACGAGGCGAAAGC
GGTGCAGCAGACGATCGAGCAGATCGACGTGATGAAGCGGCTGGTCGCGCGCTATCCCGCCGACCTGATGCTCGCCGACA
ATTCCGCCGAGCTGGAAAAGGCGATGAAGGCGGGCAAGGTCGCCGGGATGCTGGGGATCGAGGGCGGGCATTCGATCGGG
TCGAGCCTGGCGGTGCTGCGCGAAATGTATGGCATGGGCGTACGCTATATGACGCTGACCCACGGCAGAAATGTGCCATG
GGCCGACAGCGCGACCGACGCACCGGAGCATGGCGGCCTCACCGATTTCGGGCGCCAGGTGGTCCAGGAAATGAACCGCA
TCGGCATGATCGTCGATCTGAGCCACGTCAGCGAGGCGACGATGAAGGATGCGCTCGCGGCGTCGAAGGCGCCGGTGATG
TTCAGCCATTCGGGCGTGCGCGCGATAAACGATCATCCGCGCAATGTCCCCGACAGCGTGCTGCCCGCGGTGAAGGCCAA
TGGCGGGATCGTGATGGTGGTGTTCCTGCCGGGCTTCCTCGACGCCGATGTCCGCGCGCATGGCCTCGACCGCACTGGCG
TGGAGGCGCGGCTGAAGGCGATGTATCCGGGCGATCCCGCGGCGGTTGCGGCGGCGCTCACGGCGTGGGACGCTGCGAAC
CCCGCCCCGAAAACGCAGATTGCCAGGGTCGCCGACCATATCGACCATCTGAAACACATGATCGGCGTCGACCATATCGG
ACTCGGCGGCGACTATGACGGTATGGATTCGGCGCCCGTGGGCATGGAGGATGTCGCGGGCTATCCGGCGCTGTTCGTCG
AGCTGGCGCGGCGCGGCTATTCGCAGGCCGAGCTGGAGAAGATTGCGAGCGGCAACATGCTGCGCGTGCTGAAGGCGGTC
GAGGCCTTTGCCGCAAGCCAGAAGGGTCAGCCGCCGGTCGAAACGCCGGTGGCGAAATAG

Upstream 100 bases:

>100_bases
GTCATGCACCGATGCTGCGCGGGGTTGACGTAAACGTCAAGGTGCCTTTCTTTCGCCCGCGCGCTTGCGCTGCGCGATCA
AGCGGTTAGGGTCGCGCGCC

Downstream 100 bases:

>100_bases
CCTATCGGTCCGTACCGTGCCGAAATGGCCACTCCACCGCGCCGCTTGCCCATAGCGCCCACCAGATGATGAGTGGCTGC
GCGGCGAGGCGGGGGCCGTG

Product: membrane dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNKASLLVSLAALALVSSPVAAQTSPEAVAAAALKKAPVFDGHNDVPWALRARVDNVINDFDFVDTTDTATGDRIAMHTD
LTRLRRGHVGAQFWSVYVPSTTNEAKAVQQTIEQIDVMKRLVARYPADLMLADNSAELEKAMKAGKVAGMLGIEGGHSIG
SSLAVLREMYGMGVRYMTLTHGRNVPWADSATDAPEHGGLTDFGRQVVQEMNRIGMIVDLSHVSEATMKDALAASKAPVM
FSHSGVRAINDHPRNVPDSVLPAVKANGGIVMVVFLPGFLDADVRAHGLDRTGVEARLKAMYPGDPAAVAAALTAWDAAN
PAPKTQIARVADHIDHLKHMIGVDHIGLGGDYDGMDSAPVGMEDVAGYPALFVELARRGYSQAELEKIASGNMLRVLKAV
EAFAASQKGQPPVETPVAK

Sequences:

>Translated_419_residues
MNKASLLVSLAALALVSSPVAAQTSPEAVAAAALKKAPVFDGHNDVPWALRARVDNVINDFDFVDTTDTATGDRIAMHTD
LTRLRRGHVGAQFWSVYVPSTTNEAKAVQQTIEQIDVMKRLVARYPADLMLADNSAELEKAMKAGKVAGMLGIEGGHSIG
SSLAVLREMYGMGVRYMTLTHGRNVPWADSATDAPEHGGLTDFGRQVVQEMNRIGMIVDLSHVSEATMKDALAASKAPVM
FSHSGVRAINDHPRNVPDSVLPAVKANGGIVMVVFLPGFLDADVRAHGLDRTGVEARLKAMYPGDPAAVAAALTAWDAAN
PAPKTQIARVADHIDHLKHMIGVDHIGLGGDYDGMDSAPVGMEDVAGYPALFVELARRGYSQAELEKIASGNMLRVLKAV
EAFAASQKGQPPVETPVAK
>Mature_419_residues
MNKASLLVSLAALALVSSPVAAQTSPEAVAAAALKKAPVFDGHNDVPWALRARVDNVINDFDFVDTTDTATGDRIAMHTD
LTRLRRGHVGAQFWSVYVPSTTNEAKAVQQTIEQIDVMKRLVARYPADLMLADNSAELEKAMKAGKVAGMLGIEGGHSIG
SSLAVLREMYGMGVRYMTLTHGRNVPWADSATDAPEHGGLTDFGRQVVQEMNRIGMIVDLSHVSEATMKDALAASKAPVM
FSHSGVRAINDHPRNVPDSVLPAVKANGGIVMVVFLPGFLDADVRAHGLDRTGVEARLKAMYPGDPAAVAAALTAWDAAN
PAPKTQIARVADHIDHLKHMIGVDHIGLGGDYDGMDSAPVGMEDVAGYPALFVELARRGYSQAELEKIASGNMLRVLKAV
EAFAASQKGQPPVETPVAK

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=393, Percent_Identity=40.2035623409669, Blast_Score=301, Evalue=7e-82,
Organism=Homo sapiens, GI4758190, Length=393, Percent_Identity=40.2035623409669, Blast_Score=301, Evalue=7e-82,
Organism=Homo sapiens, GI11641269, Length=390, Percent_Identity=41.025641025641, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI193211608, Length=390, Percent_Identity=39.2307692307692, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI193211610, Length=390, Percent_Identity=39.2307692307692, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI221475880, Length=420, Percent_Identity=42.3809523809524, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI281362638, Length=377, Percent_Identity=43.236074270557, Blast_Score=314, Evalue=7e-86,
Organism=Drosophila melanogaster, GI281362636, Length=377, Percent_Identity=43.236074270557, Blast_Score=314, Evalue=7e-86,
Organism=Drosophila melanogaster, GI161083233, Length=368, Percent_Identity=37.5, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21356391, Length=336, Percent_Identity=30.3571428571429, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 44508; Mature: 44508

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00869 RENAL_DIPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKASLLVSLAALALVSSPVAAQTSPEAVAAAALKKAPVFDGHNDVPWALRARVDNVIND
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
FDFVDTTDTATGDRIAMHTDLTRLRRGHVGAQFWSVYVPSTTNEAKAVQQTIEQIDVMKR
CCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LVARYPADLMLADNSAELEKAMKAGKVAGMLGIEGGHSIGSSLAVLREMYGMGVRYMTLT
HHHHCCCCEEEECCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCEEEEEEE
HGRNVPWADSATDAPEHGGLTDFGRQVVQEMNRIGMIVDLSHVSEATMKDALAASKAPVM
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHCCCCEE
FSHSGVRAINDHPRNVPDSVLPAVKANGGIVMVVFLPGFLDADVRAHGLDRTGVEARLKA
EECCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCHHHCCCCCCCHHHHHEE
MYPGDPAAVAAALTAWDAANPAPKTQIARVADHIDHLKHMIGVDHIGLGGDYDGMDSAPV
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GMEDVAGYPALFVELARRGYSQAELEKIASGNMLRVLKAVEAFAASQKGQPPVETPVAK
CHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKASLLVSLAALALVSSPVAAQTSPEAVAAAALKKAPVFDGHNDVPWALRARVDNVIND
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
FDFVDTTDTATGDRIAMHTDLTRLRRGHVGAQFWSVYVPSTTNEAKAVQQTIEQIDVMKR
CCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LVARYPADLMLADNSAELEKAMKAGKVAGMLGIEGGHSIGSSLAVLREMYGMGVRYMTLT
HHHHCCCCEEEECCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCEEEEEEE
HGRNVPWADSATDAPEHGGLTDFGRQVVQEMNRIGMIVDLSHVSEATMKDALAASKAPVM
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHCCCCEE
FSHSGVRAINDHPRNVPDSVLPAVKANGGIVMVVFLPGFLDADVRAHGLDRTGVEARLKA
EECCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCHHHCCCCCCCHHHHHEE
MYPGDPAAVAAALTAWDAANPAPKTQIARVADHIDHLKHMIGVDHIGLGGDYDGMDSAPV
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GMEDVAGYPALFVELARRGYSQAELEKIASGNMLRVLKAVEAFAASQKGQPPVETPVAK
CHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]