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The map label for this gene is nudC [H]

Identifier: 103487745

GI number: 103487745

Start: 2382600

End: 2383469

Strand: Reverse

Name: nudC [H]

Synonym: Sala_2264

Alternate gene names: 103487745

Gene position: 2383469-2382600 (Counterclockwise)

Preceding gene: 103487746

Following gene: 103487741

Centisome position: 71.25

GC content: 71.72

Gene sequence:

>870_bases
ATGCCGCTGCCGCTCGGCTTCACCGGCGCGCGGCTCGACCGCGCCGACCAGCTTCGCACCAATGAAGCCGCCTTTGCCGC
GGCGCTCGCCGATCCGCGCGCGACCTGCCTCGCGCTCGACGGGATCGACTTTGTTCCGGGCGAGGGTGGCGGATTGCGGT
GGCAGCCGCTCGACCCCGCCGACGAGCGCGCGCCGATACTGCTGGGCATCGACGAGGCGGGCGCGCCGCGCTTCGTGCGC
GAGGCGGCGGCGGGGGTGCGCGTCGATGCGCGCTCGCGCACGGTGATGCGGCTGCTGCCGCTGCTCTCCACCGAGGAAGC
GGCGCTGTATGGCGGCGCGCGCAGTCTGGTCGACTGGCACGCGCGGCATCGTTACTGCGCGGTGTGCGGATCGCCGACGG
TGCTGATTCGCGGCGGCTGGGGGCGGCGCTGCGGCAACTGCAACGCCGAACATTTCCCGCGCGTCGACCCGGTGGTGATC
ATGCTCGCCGAATATGGGGACCGCGTACTCGTCGGGCGCCAGCCGGGCTTTCCGCCGCGCTTTTTCTCGGCGCTCGCGGG
CTTCGTCGAGCCCGGCGAATCGCTGGAGGAAGCGGTCGCGCGCGAATTGTTCGAGGAGGCAGGCATCCATGTGTCCGAGG
TCACCTATGTGGCGAGCCAGCCCTGGCCCTTTCCTTCCTCGCTGATGATCGGGTGCCGCGCGGTCGCGACTGGCGCGGCG
CTGACGCTCGATACGACCGAGATCGAGGCGGCGATGTGGGTCGACCGCGCCGAGGTGCACGCCGCGCTGGCGGGCGACAT
GGGCGCGCCGTTCATGGCGCCGCCGCCGCTGGCGATTGCGCGCTATTTGCTGGAGGATTGGGTGGGGTAG

Upstream 100 bases:

>100_bases
TCGGTTATCGCGCCGCCGGCTATACGCAGATCATGCCACCCGATGCAGTGCCCTTTCAGGCGAAGTTCGGCGAGACTTTC
TTTCGCGACGTGACCGCCTG

Downstream 100 bases:

>100_bases
CGGGGAAGGTTCGACGCTTAGGCGGTTTGGGTTGGTGCGTGGTCGTTCCAATCGACCGTCGCCCCCGCGAAGGCGGGGGC
CGTCCTCGGCCTTGTCCCGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MPLPLGFTGARLDRADQLRTNEAAFAAALADPRATCLALDGIDFVPGEGGGLRWQPLDPADERAPILLGIDEAGAPRFVR
EAAAGVRVDARSRTVMRLLPLLSTEEAALYGGARSLVDWHARHRYCAVCGSPTVLIRGGWGRRCGNCNAEHFPRVDPVVI
MLAEYGDRVLVGRQPGFPPRFFSALAGFVEPGESLEEAVARELFEEAGIHVSEVTYVASQPWPFPSSLMIGCRAVATGAA
LTLDTTEIEAAMWVDRAEVHAALAGDMGAPFMAPPPLAIARYLLEDWVG

Sequences:

>Translated_289_residues
MPLPLGFTGARLDRADQLRTNEAAFAAALADPRATCLALDGIDFVPGEGGGLRWQPLDPADERAPILLGIDEAGAPRFVR
EAAAGVRVDARSRTVMRLLPLLSTEEAALYGGARSLVDWHARHRYCAVCGSPTVLIRGGWGRRCGNCNAEHFPRVDPVVI
MLAEYGDRVLVGRQPGFPPRFFSALAGFVEPGESLEEAVARELFEEAGIHVSEVTYVASQPWPFPSSLMIGCRAVATGAA
LTLDTTEIEAAMWVDRAEVHAALAGDMGAPFMAPPPLAIARYLLEDWVG
>Mature_288_residues
PLPLGFTGARLDRADQLRTNEAAFAAALADPRATCLALDGIDFVPGEGGGLRWQPLDPADERAPILLGIDEAGAPRFVRE
AAAGVRVDARSRTVMRLLPLLSTEEAALYGGARSLVDWHARHRYCAVCGSPTVLIRGGWGRRCGNCNAEHFPRVDPVVIM
LAEYGDRVLVGRQPGFPPRFFSALAGFVEPGESLEEAVARELFEEAGIHVSEVTYVASQPWPFPSSLMIGCRAVATGAAL
TLDTTEIEAAMWVDRAEVHAALAGDMGAPFMAPPPLAIARYLLEDWVG

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=197, Percent_Identity=45.6852791878173, Blast_Score=178, Evalue=5e-45,
Organism=Homo sapiens, GI50593112, Length=198, Percent_Identity=39.3939393939394, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI48994995, Length=180, Percent_Identity=35, Blast_Score=117, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71986510, Length=213, Percent_Identity=30.9859154929577, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI212645999, Length=213, Percent_Identity=30.9859154929577, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321371, Length=194, Percent_Identity=35.0515463917526, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 31016; Mature: 30885

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPLGFTGARLDRADQLRTNEAAFAAALADPRATCLALDGIDFVPGEGGGLRWQPLDPA
CCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCEEEEEECCCEECCCCCCCEECCCCCCC
DERAPILLGIDEAGAPRFVREAAAGVRVDARSRTVMRLLPLLSTEEAALYGGARSLVDWH
CCCCCEEEEECCCCCCHHHHHHHCCCEECCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHH
ARHRYCAVCGSPTVLIRGGWGRRCGNCNAEHFPRVDPVVIMLAEYGDRVLVGRQPGFPPR
HHCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCHH
FFSALAGFVEPGESLEEAVARELFEEAGIHVSEVTYVASQPWPFPSSLMIGCRAVATGAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEHEEEEECCCCCCCHHHHHHHHHHHCCCE
LTLDTTEIEAAMWVDRAEVHAALAGDMGAPFMAPPPLAIARYLLEDWVG
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLPLGFTGARLDRADQLRTNEAAFAAALADPRATCLALDGIDFVPGEGGGLRWQPLDPA
CCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCEEEEEECCCEECCCCCCCEECCCCCCC
DERAPILLGIDEAGAPRFVREAAAGVRVDARSRTVMRLLPLLSTEEAALYGGARSLVDWH
CCCCCEEEEECCCCCCHHHHHHHCCCEECCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHH
ARHRYCAVCGSPTVLIRGGWGRRCGNCNAEHFPRVDPVVIMLAEYGDRVLVGRQPGFPPR
HHCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCHH
FFSALAGFVEPGESLEEAVARELFEEAGIHVSEVTYVASQPWPFPSSLMIGCRAVATGAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEHEEEEECCCCCCCHHHHHHHHHHHCCCE
LTLDTTEIEAAMWVDRAEVHAALAGDMGAPFMAPPPLAIARYLLEDWVG
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]