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The map label for this gene is lip2 [H]

Identifier: 103487723

GI number: 103487723

Start: 2354583

End: 2355584

Strand: Reverse

Name: lip2 [H]

Synonym: Sala_2242

Alternate gene names: 103487723

Gene position: 2355584-2354583 (Counterclockwise)

Preceding gene: 103487728

Following gene: 103487722

Centisome position: 70.42

GC content: 70.36

Gene sequence:

>1002_bases
ATGTTACGCGCTTGTGACGCGCCGCGCGGCGCTGTAGGGCGCGGCGGGATGGCGGCGCGGCTTTGCAAGGGACGGCGATT
GATCAAGATCCTCTTCGTGCTGCTGCTGCTCGTGCTGCTGTTCGGCGGCGGCGCCAGGATGATCGCCGCGGGCGGCGCGA
AATCGCTCAACCTGGCCGACCGGCTGCTGGGGCAGGGCGATGGCGCGCGGCTGCTGATCGCCGACCAGCCCTATGGCCGC
GGGCCGCGCCAGTCGCTCGACATCTGGGTGCCGGGCAGCCTGCGCGAAGGCGACCGGCTGCCCGTCGTGGTCTTTTTCTA
TGGCGGCGGCTGGAACAGCGGCGAGCGCGGCCATTATGGTTTCGCGGGACGCGCGCTCGCGCGGCAGGGCTTTGTCGTCG
TGATCCCCGATTACCGGCTGGTGCCGAAGGCGCATTGGCCCGATTTTCTGGAAGACAGCGCCGCGGCGGTCGCGTGGACG
CATGAGCATATCGCGAAGCTCGGCGGCGATCCCGACCGGATCGCGCTGATGGGGCATTCGGCGGGCGCCTATAATGCCGC
GATGCTCGCGCTCGACCCGCAATGGTTGCGCGCCGCGAAAAGCGATCCGTCGATCGTCCGCGGCGTCGCGGGCCTTGCCG
GGCCTTATGACTTCCTGCCGCTCGAAAAGGGCGGCCGCGCCGACAAGGCGATGGGCAAGGTTCGGCCGATCGAGCGGACG
CAGCCGATCCATTTCGCGCGCGGCGACGCGCCGCCGCTTTGGCTTGCGAGCGGCGACGAGGATGATGTGGTGCGCCCGCG
CAACAGCCAGAACCTCGCCGCCGCGATCGAGCGCGCGGGCGGGTCGGCGACGCTGCGCATCTATCCCGGCGTCGGCCACA
CCGGGATCGTCATGGCGCTCGCCGCGCCCTTTCGCAACCGCGGGCCGGTGCTCGACGAAGCGAGCGATTTCCTTCGCGGT
GTCACCGCGCGCCGCATCGCGCCGGTGGACGCAGAGCGATGA

Upstream 100 bases:

>100_bases
GCTGCCGCTGTGGCTGTTGCAGACAAGGGCGGGGCGGGAAAAGGGGCAGGTCATCGCCTTCTTCTACGCGCGAGCGGACA
AAAGGTCGCGCGCCGCGCCA

Downstream 100 bases:

>100_bases
CCGGCCCGATAGCGGCGATCGTCCTCGCGGGCAGCCGTCCCGGCGCCGACCCGCTGCTGGCGGGCAGCGGGGTGCCCACC
AAGGCGCTGCTCCCCGTCGC

Product: Alpha/beta hydrolase fold-3

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MLRACDAPRGAVGRGGMAARLCKGRRLIKILFVLLLLVLLFGGGARMIAAGGAKSLNLADRLLGQGDGARLLIADQPYGR
GPRQSLDIWVPGSLREGDRLPVVVFFYGGGWNSGERGHYGFAGRALARQGFVVVIPDYRLVPKAHWPDFLEDSAAAVAWT
HEHIAKLGGDPDRIALMGHSAGAYNAAMLALDPQWLRAAKSDPSIVRGVAGLAGPYDFLPLEKGGRADKAMGKVRPIERT
QPIHFARGDAPPLWLASGDEDDVVRPRNSQNLAAAIERAGGSATLRIYPGVGHTGIVMALAAPFRNRGPVLDEASDFLRG
VTARRIAPVDAER

Sequences:

>Translated_333_residues
MLRACDAPRGAVGRGGMAARLCKGRRLIKILFVLLLLVLLFGGGARMIAAGGAKSLNLADRLLGQGDGARLLIADQPYGR
GPRQSLDIWVPGSLREGDRLPVVVFFYGGGWNSGERGHYGFAGRALARQGFVVVIPDYRLVPKAHWPDFLEDSAAAVAWT
HEHIAKLGGDPDRIALMGHSAGAYNAAMLALDPQWLRAAKSDPSIVRGVAGLAGPYDFLPLEKGGRADKAMGKVRPIERT
QPIHFARGDAPPLWLASGDEDDVVRPRNSQNLAAAIERAGGSATLRIYPGVGHTGIVMALAAPFRNRGPVLDEASDFLRG
VTARRIAPVDAER
>Mature_333_residues
MLRACDAPRGAVGRGGMAARLCKGRRLIKILFVLLLLVLLFGGGARMIAAGGAKSLNLADRLLGQGDGARLLIADQPYGR
GPRQSLDIWVPGSLREGDRLPVVVFFYGGGWNSGERGHYGFAGRALARQGFVVVIPDYRLVPKAHWPDFLEDSAAAVAWT
HEHIAKLGGDPDRIALMGHSAGAYNAAMLALDPQWLRAAKSDPSIVRGVAGLAGPYDFLPLEKGGRADKAMGKVRPIERT
QPIHFARGDAPPLWLASGDEDDVVRPRNSQNLAAAIERAGGSATLRIYPGVGHTGIVMALAAPFRNRGPVLDEASDFLRG
VTARRIAPVDAER

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI192807282, Length=145, Percent_Identity=33.7931034482759, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI224465228, Length=145, Percent_Identity=33.7931034482759, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310117651, Length=161, Percent_Identity=32.9192546583851, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI310117649, Length=161, Percent_Identity=32.9192546583851, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI148536848, Length=161, Percent_Identity=32.9192546583851, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 35524; Mature: 35524

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRACDAPRGAVGRGGMAARLCKGRRLIKILFVLLLLVLLFGGGARMIAAGGAKSLNLAD
CCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
RLLGQGDGARLLIADQPYGRGPRQSLDIWVPGSLREGDRLPVVVFFYGGGWNSGERGHYG
HHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCC
FAGRALARQGFVVVIPDYRLVPKAHWPDFLEDSAAAVAWTHEHIAKLGGDPDRIALMGHS
CHHHHHHHCCCEEEECCCEECCCCCCCHHHHCCCCEEEECHHHHHHHCCCCCEEEEEECC
AGAYNAAMLALDPQWLRAAKSDPSIVRGVAGLAGPYDFLPLEKGGRADKAMGKVRPIERT
CCCCCEEEEEECHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCC
QPIHFARGDAPPLWLASGDEDDVVRPRNSQNLAAAIERAGGSATLRIYPGVGHTGIVMAL
CCEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
AAPFRNRGPVLDEASDFLRGVTARRIAPVDAER
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLRACDAPRGAVGRGGMAARLCKGRRLIKILFVLLLLVLLFGGGARMIAAGGAKSLNLAD
CCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
RLLGQGDGARLLIADQPYGRGPRQSLDIWVPGSLREGDRLPVVVFFYGGGWNSGERGHYG
HHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCC
FAGRALARQGFVVVIPDYRLVPKAHWPDFLEDSAAAVAWTHEHIAKLGGDPDRIALMGHS
CHHHHHHHCCCEEEECCCEECCCCCCCHHHHCCCCEEEECHHHHHHHCCCCCEEEEEECC
AGAYNAAMLALDPQWLRAAKSDPSIVRGVAGLAGPYDFLPLEKGGRADKAMGKVRPIERT
CCCCCEEEEEECHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCC
QPIHFARGDAPPLWLASGDEDDVVRPRNSQNLAAAIERAGGSATLRIYPGVGHTGIVMAL
CCEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
AAPFRNRGPVLDEASDFLRGVTARRIAPVDAER
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]