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The map label for this gene is degP1 [H]

Identifier: 103487728

GI number: 103487728

Start: 2359665

End: 2361158

Strand: Reverse

Name: degP1 [H]

Synonym: Sala_2247

Alternate gene names: 103487728

Gene position: 2361158-2359665 (Counterclockwise)

Preceding gene: 103487729

Following gene: 103487723

Centisome position: 70.58

GC content: 67.2

Gene sequence:

>1494_bases
GTGCGTTACGTATATGGCATCACTTCGGCCTTGCTGGCGGGTGGCACCGCGCTGGCGCTGGTCACCCAGTCGCCCGTCGG
CGCGCAGGTCGCGCAGAACGAACAGAGCGAAATGGCACGCGTCGTCCCGCGCGCGGGCGCGCCGGACAGCTTTGCCGACC
TCGTCGAACAATTGCAGCCTGCGGTCGTCAATATCTCGACCAAGCAGGAAGTGACGCTCGGCGTACGCCTCAACCCCTTT
GCCGGCACGCGCGAGCCGATCACGCAGGAGCAGCAGGGCGGCGGATCGGGTTTCCTCATTTCGTCGGACGGCTATATCGT
CACCAACAACCACGTCATTTCGGGCGGACCGCGCGGCGAAGCCGTGAACGAGGTTACTGTCACGCTGACCAACCAGCGCG
AATATAAGGCGAAGATCGTCGGTCGCGATGTGGCGTCGGACCTTGCGCTGCTCAAGATCGACGCCACCGGCCTGCCCTTC
GTCAAATTCGCGCAAGGCAGCCCGGCGCGCGTCGGCGACTGGGTGGTCGCGATCGGCAACCCGCTCGGGCTCGGCTCGAC
AGTGACCGCGGGGATCATTTCGGCGGTGCAGCGCAACATCGGGCAGGGCGGCGCCTATGACCGCTATATCCAGACCGATA
CCGCGATCAACCGCGGCAATTCGGGCGGTCCGCTGTTCGACCTGCAGGGCAATGTCGTCGGCATCAACAATATGCTGATC
TCTCCCGTCGGCGCGAACATCGGCGTCAATTTCGCGATCCCCGCCGAAGCGGCGATCCCGGTGATCGAGGCGCTGCGCGC
GGGCGAGCGACCGCAGCGCGGCTATCTGGGCATCGGCATCGTTCCGGTGACCGAAGACATTGCGGCGGCGCTCGGCCTGC
CCAAGGACCGCGGCGAGTTCGTCCAGCGCGTCGAACCCGGCGAAGCGGGCGAAAAGGCCGGGCTGAAGCGCGGCGACGTG
GTGCTGAAAGTCAATGGCCGCGATGTCACGCCGCAGCAGACTTTGTCCTACATCGTCGCCAACACCAAGCCCGGCACGCG
CATCCCGCTCGAAATCGTGCGCGACGGGCGGACAATGACGCTGAATGCCGTCGTTGGCACGCGCCCGCCCGAAGAGCAGC
TCGCCGGGGACAATTTCGACCCCGAAGAGGAACAGACGATGCCCGAGGATCCATCGGGCGCGGCCGACGAGACGATCCAG
AACAGCCTGGGCATGGCGGTGCAGCCGTTGACCCCGGCGATCGCGCGCGCCGTCGGCATCGACCCCGACAGCAAGGGGCT
CGTCATCGCCGCGGTCGCGGGCAGCAGCGACGCGGGCCGCAAGGGGCTGCGCCGCGGCGACGCGATCCTGAGCGCCAATC
GCACGCCGGTCACCTCGGCGGAGGCGCTGGCGAAGGTCATCACCGACGCCAAAAAGGCGGGGCGCGACGCGGTGCTGCTG
GAAATCCTGCGGCGCGGCGGCCCGTCGGCCTTCATTGCGATCCGCCTCAAATAA

Upstream 100 bases:

>100_bases
CGTCTCGCGCTTGTTCATGTTCAATCGGCGTTCAGCCGCCCCGCCGCAGAGACCGGCGGCCGGGGTTTGAAGTTTACCTA
GACGAAGAGGATTTCCGATC

Downstream 100 bases:

>100_bases
ACGGCGACGGACACGGTCGACGCGATCGGGGGCGCTGCGATTGCAGCGCCCCTTTTTCTTGCGGCGGGCATCGGGCTGAC
CGGGCTCTTCGACGCCGATT

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MRYVYGITSALLAGGTALALVTQSPVGAQVAQNEQSEMARVVPRAGAPDSFADLVEQLQPAVVNISTKQEVTLGVRLNPF
AGTREPITQEQQGGGSGFLISSDGYIVTNNHVISGGPRGEAVNEVTVTLTNQREYKAKIVGRDVASDLALLKIDATGLPF
VKFAQGSPARVGDWVVAIGNPLGLGSTVTAGIISAVQRNIGQGGAYDRYIQTDTAINRGNSGGPLFDLQGNVVGINNMLI
SPVGANIGVNFAIPAEAAIPVIEALRAGERPQRGYLGIGIVPVTEDIAAALGLPKDRGEFVQRVEPGEAGEKAGLKRGDV
VLKVNGRDVTPQQTLSYIVANTKPGTRIPLEIVRDGRTMTLNAVVGTRPPEEQLAGDNFDPEEEQTMPEDPSGAADETIQ
NSLGMAVQPLTPAIARAVGIDPDSKGLVIAAVAGSSDAGRKGLRRGDAILSANRTPVTSAEALAKVITDAKKAGRDAVLL
EILRRGGPSAFIAIRLK

Sequences:

>Translated_497_residues
MRYVYGITSALLAGGTALALVTQSPVGAQVAQNEQSEMARVVPRAGAPDSFADLVEQLQPAVVNISTKQEVTLGVRLNPF
AGTREPITQEQQGGGSGFLISSDGYIVTNNHVISGGPRGEAVNEVTVTLTNQREYKAKIVGRDVASDLALLKIDATGLPF
VKFAQGSPARVGDWVVAIGNPLGLGSTVTAGIISAVQRNIGQGGAYDRYIQTDTAINRGNSGGPLFDLQGNVVGINNMLI
SPVGANIGVNFAIPAEAAIPVIEALRAGERPQRGYLGIGIVPVTEDIAAALGLPKDRGEFVQRVEPGEAGEKAGLKRGDV
VLKVNGRDVTPQQTLSYIVANTKPGTRIPLEIVRDGRTMTLNAVVGTRPPEEQLAGDNFDPEEEQTMPEDPSGAADETIQ
NSLGMAVQPLTPAIARAVGIDPDSKGLVIAAVAGSSDAGRKGLRRGDAILSANRTPVTSAEALAKVITDAKKAGRDAVLL
EILRRGGPSAFIAIRLK
>Mature_497_residues
MRYVYGITSALLAGGTALALVTQSPVGAQVAQNEQSEMARVVPRAGAPDSFADLVEQLQPAVVNISTKQEVTLGVRLNPF
AGTREPITQEQQGGGSGFLISSDGYIVTNNHVISGGPRGEAVNEVTVTLTNQREYKAKIVGRDVASDLALLKIDATGLPF
VKFAQGSPARVGDWVVAIGNPLGLGSTVTAGIISAVQRNIGQGGAYDRYIQTDTAINRGNSGGPLFDLQGNVVGINNMLI
SPVGANIGVNFAIPAEAAIPVIEALRAGERPQRGYLGIGIVPVTEDIAAALGLPKDRGEFVQRVEPGEAGEKAGLKRGDV
VLKVNGRDVTPQQTLSYIVANTKPGTRIPLEIVRDGRTMTLNAVVGTRPPEEQLAGDNFDPEEEQTMPEDPSGAADETIQ
NSLGMAVQPLTPAIARAVGIDPDSKGLVIAAVAGSSDAGRKGLRRGDAILSANRTPVTSAEALAKVITDAKKAGRDAVLL
EILRRGGPSAFIAIRLK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=309, Percent_Identity=36.2459546925566, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI22129776, Length=306, Percent_Identity=34.3137254901961, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI24308541, Length=295, Percent_Identity=31.864406779661, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI7019477, Length=330, Percent_Identity=32.7272727272727, Blast_Score=139, Evalue=8e-33,
Organism=Escherichia coli, GI1789629, Length=458, Percent_Identity=33.4061135371179, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1786356, Length=502, Percent_Identity=30.4780876494024, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1789630, Length=327, Percent_Identity=33.3333333333333, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24646839, Length=299, Percent_Identity=35.4515050167224, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 51729; Mature: 51729

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVYGITSALLAGGTALALVTQSPVGAQVAQNEQSEMARVVPRAGAPDSFADLVEQLQP
CEEEHHHHHHHHCCCEEEEEEECCCCCCHHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCC
AVVNISTKQEVTLGVRLNPFAGTREPITQEQQGGGSGFLISSDGYIVTNNHVISGGPRGE
EEEEECCCCEEEEEEEECCCCCCCCCCCHHHCCCCCEEEEECCCEEEECCEEECCCCCCC
AVNEVTVTLTNQREYKAKIVGRDVASDLALLKIDATGLPFVKFAQGSPARVGDWVVAIGN
CCCEEEEEEECCCCEEEEEECCHHHCCEEEEEEECCCCCEEEECCCCCCCCCCEEEEECC
PLGLGSTVTAGIISAVQRNIGQGGAYDRYIQTDTAINRGNSGGPLFDLQGNVVGINNMLI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHCCCCCCCCEEEECCCEEEECCEEE
SPVGANIGVNFAIPAEAAIPVIEALRAGERPQRGYLGIGIVPVTEDIAAALGLPKDRGEF
ECCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHCCCCCHHHH
VQRVEPGEAGEKAGLKRGDVVLKVNGRDVTPQQTLSYIVANTKPGTRIPLEIVRDGRTMT
HHHCCCCCCCHHCCCCCCCEEEEECCCCCCHHHHEEEEEECCCCCCCCCHHEECCCCEEE
LNAVVGTRPPEEQLAGDNFDPEEEQTMPEDPSGAADETIQNSLGMAVQPLTPAIARAVGI
EEEEECCCCCHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHCC
DPDSKGLVIAAVAGSSDAGRKGLRRGDAILSANRTPVTSAEALAKVITDAKKAGRDAVLL
CCCCCCEEEEEEECCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHH
EILRRGGPSAFIAIRLK
HHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MRYVYGITSALLAGGTALALVTQSPVGAQVAQNEQSEMARVVPRAGAPDSFADLVEQLQP
CEEEHHHHHHHHCCCEEEEEEECCCCCCHHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCC
AVVNISTKQEVTLGVRLNPFAGTREPITQEQQGGGSGFLISSDGYIVTNNHVISGGPRGE
EEEEECCCCEEEEEEEECCCCCCCCCCCHHHCCCCCEEEEECCCEEEECCEEECCCCCCC
AVNEVTVTLTNQREYKAKIVGRDVASDLALLKIDATGLPFVKFAQGSPARVGDWVVAIGN
CCCEEEEEEECCCCEEEEEECCHHHCCEEEEEEECCCCCEEEECCCCCCCCCCEEEEECC
PLGLGSTVTAGIISAVQRNIGQGGAYDRYIQTDTAINRGNSGGPLFDLQGNVVGINNMLI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHCCCCCCCCEEEECCCEEEECCEEE
SPVGANIGVNFAIPAEAAIPVIEALRAGERPQRGYLGIGIVPVTEDIAAALGLPKDRGEF
ECCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHHCCCCCHHHH
VQRVEPGEAGEKAGLKRGDVVLKVNGRDVTPQQTLSYIVANTKPGTRIPLEIVRDGRTMT
HHHCCCCCCCHHCCCCCCCEEEEECCCCCCHHHHEEEEEECCCCCCCCCHHEECCCCEEE
LNAVVGTRPPEEQLAGDNFDPEEEQTMPEDPSGAADETIQNSLGMAVQPLTPAIARAVGI
EEEEECCCCCHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHCC
DPDSKGLVIAAVAGSSDAGRKGLRRGDAILSANRTPVTSAEALAKVITDAKKAGRDAVLL
CCCCCCEEEEEEECCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHH
EILRRGGPSAFIAIRLK
HHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]