Click here to switch to the map view.

The map label for this gene is erpA [H]

Identifier: 103487662

GI number: 103487662

Start: 2291622

End: 2291990

Strand: Reverse

Name: erpA [H]

Synonym: Sala_2181

Alternate gene names: 103487662

Gene position: 2291990-2291622 (Counterclockwise)

Preceding gene: 103487663

Following gene: 103487661

Centisome position: 68.52

GC content: 65.31

Gene sequence:

>369_bases
TTGGGCGCGCATCCCTATCTTGCCGCCATGGCCACGCAGATTTCCGACATCATCCTGTCGCCCGCCGCCGCGGCGCGCGT
CCGCTGGATCGCCGATCGCAAGGGTCAGGCCGAGGCGGCGCTGCGCCTGTCGGTCGACGGCGGCGGCTGTTCGGGTTTCA
CCTATCGTTTCGACCTTGCCGACAGCATCGACGCCGACGACATCGTCACCGAAACCGACGGGGTGAAGCTGGTCGTCGAT
CCGGTCAGCATCGACCTGGTGCGTGGCTGCACCGTCGATTTCGTCGATTCGCTCGGTGGATCGTCGTTCAAGGTCGAAAA
TCCCAACGCGGCATCGGGCTGCGGCTGCGGATCGAGCTTCGCGATCTGA

Upstream 100 bases:

>100_bases
AAAATGTCGCGATGGGCGGTCCTGAATAGGAATAAAACGAGCCTTTCCGGGTCGGAGAGGAGGGGGCGTTCCGCGGCTGA
TGCCGGGACGCCCTTTTCTT

Downstream 100 bases:

>100_bases
GCAATCCACTCCTTGTCCTTCTTCGCCGCGCTCGCAATGACGAAATTGCGGACGTCAAAGGAATGATCGCCAAACAAGTT
CCGGGTGACGAAGGGGCTGT

Product: HesB/YadR/YfhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MGAHPYLAAMATQISDIILSPAAAARVRWIADRKGQAEAALRLSVDGGGCSGFTYRFDLADSIDADDIVTETDGVKLVVD
PVSIDLVRGCTVDFVDSLGGSSFKVENPNAASGCGCGSSFAI

Sequences:

>Translated_122_residues
MGAHPYLAAMATQISDIILSPAAAARVRWIADRKGQAEAALRLSVDGGGCSGFTYRFDLADSIDADDIVTETDGVKLVVD
PVSIDLVRGCTVDFVDSLGGSSFKVENPNAASGCGCGSSFAI
>Mature_121_residues
GAHPYLAAMATQISDIILSPAAAARVRWIADRKGQAEAALRLSVDGGGCSGFTYRFDLADSIDADDIVTETDGVKLVVDP
VSIDLVRGCTVDFVDSLGGSSFKVENPNAASGCGCGSSFAI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=54.2168674698795, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786351, Length=104, Percent_Identity=45.1923076923077, Blast_Score=96, Evalue=6e-22,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=42.4528301886792, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=37.7358490566038, Blast_Score=77, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71998452, Length=122, Percent_Identity=41.8032786885246, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=33.0188679245283, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=33.0188679245283, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=37.3831775700935, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325324, Length=129, Percent_Identity=29.4573643410853, Blast_Score=60, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=34.9056603773585, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12558; Mature: 12427

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAHPYLAAMATQISDIILSPAAAARVRWIADRKGQAEAALRLSVDGGGCSGFTYRFDLA
CCCCHHHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCCEEEEEEECCCCCCCEEEEEECC
DSIDADDIVTETDGVKLVVDPVSIDLVRGCTVDFVDSLGGSSFKVENPNAASGCGCGSSF
CCCCCCCEEECCCCCEEEECCCEEEEECCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCC
AI
CC
>Mature Secondary Structure 
GAHPYLAAMATQISDIILSPAAAARVRWIADRKGQAEAALRLSVDGGGCSGFTYRFDLA
CCCHHHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCCEEEEEEECCCCCCCEEEEEECC
DSIDADDIVTETDGVKLVVDPVSIDLVRGCTVDFVDSLGGSSFKVENPNAASGCGCGSSF
CCCCCCCEEECCCCCEEEECCCEEEEECCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCC
AI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]