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The map label for this gene is hppA [H]

Identifier: 103487506

GI number: 103487506

Start: 2134080

End: 2136194

Strand: Reverse

Name: hppA [H]

Synonym: Sala_2023

Alternate gene names: 103487506

Gene position: 2136194-2134080 (Counterclockwise)

Preceding gene: 103487507

Following gene: 103487505

Centisome position: 63.86

GC content: 64.92

Gene sequence:

>2115_bases
ATGAATCCGGTTTTGATCGCGATAGCGTGCGGCCTGTTGGCCGTACTCTATGGATTCATTACCTCGCGGCAGGTGCTCAG
CGCCTCCGCCGGTAATGAGAAGATGCAGGAAATCGCTGGCGCCATCCAGGAAGGCGCCAAGGCGTATCTGGGCCGCCAGT
ATCGCACCATCGCCGTCGTCGGCGTTGTTGTCGCCGTGCTTGTCGGGGTCTTCCTCGGCCCGATTTCGGCGACGGGTTTC
GTCATCGGCGCCGTGCTGTCGGGTGTGGCCGGCTATATCGGCATGAACATTTCGGTCCGCGCGAACGTGCGCACCGCGGC
GGCAGCGCAGACGGGGCTGCAGGCGGGCCTGACCATGGCGTTTCGCGCCGGCGCGATCACCGGAATGCTGGTGGCGGGTC
TCGCGCTGCTCGCGATCTCGGTCTTCTTCTGGTATCTCACGGGCCCAGGCGGCTTTTCCGTCGGCGGCGATGACCGCACC
GTGGTCGATGCGCTCGTCGCGCTGGCGTTCGGCGCGTCGCTCATCTCGATCTTCGCGCGTCTTGGCGGCGGCATCTTCAC
CAAGGCCGCCGACGTCGGCGCCGACCTCGTCGGCAAGGTGGAGGCCGGGATCCCCGAGGACGATCCGCGCAACCCCGCGG
TGATCGCCGACAATGTCGGCGACAATGTCGGCGACTGCGCCGGCATGGCCGCGGACCTTTTCGAAACCTATGTCGTCACC
GTCGGCGCCACGATGGTGCTGATCGCACTGCTGCTGAAGGGCGCGGGCGACATGCTGCTCCCGCTGATGACGCTGCCGCT
GCTGATGGGCGGCGTGTGCATCATCACCTCGATCATCGGCACCTATTTCGTGCGTCTCGGCAGCGGGACCAATGTGATGG
GCGCGATGTACAAGGGCTTCCTCGTCACCGCGATCCTGTCGATCCCGGCGATCTGGTTCGCGACCCAATATGCGCTCGGC
GACATGAATGCGGAGATTGCGGGCACCGGCTTCAACGGCCGCGCGCTCTTCTATTGTTCGCTGCTTGGCCTGGTCATCAC
CGGGCTGATCATCTGGATCACCGAATATTATACCGGCACCAATTACCGCCCGGTGCGCAGCATCGCCAAGGCGTCGGAAA
CGGGCCACGGCACCAATGTGATTCAGGGCCTTGCCGTCAGCCTGGAATCGACCGCGCTGCCGACGCTCGTCATCTGCGTC
GGCATCATTGTCGCCTATCAGGTCGCGGGTATCATCGGCATCGCCTTTGGCGCCACCGCGATGCTCGCGCTCGCGGGCAT
GGTCGTCGCGCTCGACGCCTATGGTCCCGTCACCGACAATGCCGGCGGCATTGCCGAGATGGCGGGGCTCGATGACAGCG
TGCGCGAGAAGACCGACCTGCTCGATGCCGTGGGCAACACGACCAAGGCGGTGACCAAAGGCTATGCCATCGGTTCGGCG
GGTCTGGCGGCGCTGGTGCTGTTCGGCACCTACACCGCCGACATTACCGAATATTCGGCGGAACTCGGCCTCGATGCGCC
GCTGACCTTCTCGCTGTCGTCGCCCTATGTCATCGTCGGGCTGCTGCTCGGTGCGCTCCTGCCCTATCTCTTCGGGGCGA
TGGGCATGACCGCGGTGGGCCGCGCGGCGGGTGACGTGGTCAAGGATGTTCGCGACCAGTTCGCGAACAACAAGGGCATC
ATGGATGGCACCAGTCGCCCCGATTATGCCCGCACGGTCGACCTGGTGACCAAGGCGGCGATCAAGGAAATGATCGTTCC
GTCGCTGCTGCCGGTGCTTGCGCCGATCGTCGTCTATTTCGTCATCCTGTGGGTCGCGGGTCCGGCCGCTGCGCTCGAAG
CGCTCGGCGCGCTGCTGCTCGGCGTGATCGTCGGGGGGCTGTTCGTTGCCATATCGATGACCTCGGGCGGTGGCGCGTGG
GACAATGCCAAGAAATATATCGAGGACGGCAACCACGGCGGCAAGGGCAGCGAAGCCCACAAGGCGGCCGTCACCGGCGA
TACCGTTGGCGATCCGTACAAGGATACCGCGGGCCCGGCAGTGAACCCGATGATCAAGATCACCAATATCGTGGCGATCC
TGCTCCTCGCGGCGCTGGCACACGGCGCGGCATAA

Upstream 100 bases:

>100_bases
GCGGTCGCATCAGGGGAGAGAGCGAACCGGCAACAATAGTCGGACGTGCTCGACTGCTATCTTCTGCGTCGCCCTTCTCA
TGGGGAAGGAAGCAACACGC

Downstream 100 bases:

>100_bases
GTCGCACCGCGCCTGTCGGGCAATGAAAGGCCCCGCCGGAGCGATCCGGCGGGGCCTTTTGTGTATGGCGCGGGTTTGCA
GATTGCTTGTGCGCCGACGC

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MNPVLIAIACGLLAVLYGFITSRQVLSASAGNEKMQEIAGAIQEGAKAYLGRQYRTIAVVGVVVAVLVGVFLGPISATGF
VIGAVLSGVAGYIGMNISVRANVRTAAAAQTGLQAGLTMAFRAGAITGMLVAGLALLAISVFFWYLTGPGGFSVGGDDRT
VVDALVALAFGASLISIFARLGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYVVT
VGATMVLIALLLKGAGDMLLPLMTLPLLMGGVCIITSIIGTYFVRLGSGTNVMGAMYKGFLVTAILSIPAIWFATQYALG
DMNAEIAGTGFNGRALFYCSLLGLVITGLIIWITEYYTGTNYRPVRSIAKASETGHGTNVIQGLAVSLESTALPTLVICV
GIIVAYQVAGIIGIAFGATAMLALAGMVVALDAYGPVTDNAGGIAEMAGLDDSVREKTDLLDAVGNTTKAVTKGYAIGSA
GLAALVLFGTYTADITEYSAELGLDAPLTFSLSSPYVIVGLLLGALLPYLFGAMGMTAVGRAAGDVVKDVRDQFANNKGI
MDGTSRPDYARTVDLVTKAAIKEMIVPSLLPVLAPIVVYFVILWVAGPAAALEALGALLLGVIVGGLFVAISMTSGGGAW
DNAKKYIEDGNHGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPMIKITNIVAILLLAALAHGAA

Sequences:

>Translated_704_residues
MNPVLIAIACGLLAVLYGFITSRQVLSASAGNEKMQEIAGAIQEGAKAYLGRQYRTIAVVGVVVAVLVGVFLGPISATGF
VIGAVLSGVAGYIGMNISVRANVRTAAAAQTGLQAGLTMAFRAGAITGMLVAGLALLAISVFFWYLTGPGGFSVGGDDRT
VVDALVALAFGASLISIFARLGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYVVT
VGATMVLIALLLKGAGDMLLPLMTLPLLMGGVCIITSIIGTYFVRLGSGTNVMGAMYKGFLVTAILSIPAIWFATQYALG
DMNAEIAGTGFNGRALFYCSLLGLVITGLIIWITEYYTGTNYRPVRSIAKASETGHGTNVIQGLAVSLESTALPTLVICV
GIIVAYQVAGIIGIAFGATAMLALAGMVVALDAYGPVTDNAGGIAEMAGLDDSVREKTDLLDAVGNTTKAVTKGYAIGSA
GLAALVLFGTYTADITEYSAELGLDAPLTFSLSSPYVIVGLLLGALLPYLFGAMGMTAVGRAAGDVVKDVRDQFANNKGI
MDGTSRPDYARTVDLVTKAAIKEMIVPSLLPVLAPIVVYFVILWVAGPAAALEALGALLLGVIVGGLFVAISMTSGGGAW
DNAKKYIEDGNHGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPMIKITNIVAILLLAALAHGAA
>Mature_704_residues
MNPVLIAIACGLLAVLYGFITSRQVLSASAGNEKMQEIAGAIQEGAKAYLGRQYRTIAVVGVVVAVLVGVFLGPISATGF
VIGAVLSGVAGYIGMNISVRANVRTAAAAQTGLQAGLTMAFRAGAITGMLVAGLALLAISVFFWYLTGPGGFSVGGDDRT
VVDALVALAFGASLISIFARLGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYVVT
VGATMVLIALLLKGAGDMLLPLMTLPLLMGGVCIITSIIGTYFVRLGSGTNVMGAMYKGFLVTAILSIPAIWFATQYALG
DMNAEIAGTGFNGRALFYCSLLGLVITGLIIWITEYYTGTNYRPVRSIAKASETGHGTNVIQGLAVSLESTALPTLVICV
GIIVAYQVAGIIGIAFGATAMLALAGMVVALDAYGPVTDNAGGIAEMAGLDDSVREKTDLLDAVGNTTKAVTKGYAIGSA
GLAALVLFGTYTADITEYSAELGLDAPLTFSLSSPYVIVGLLLGALLPYLFGAMGMTAVGRAAGDVVKDVRDQFANNKGI
MDGTSRPDYARTVDLVTKAAIKEMIVPSLLPVLAPIVVYFVILWVAGPAAALEALGALLLGVIVGGLFVAISMTSGGGAW
DNAKKYIEDGNHGGKGSEAHKAAVTGDTVGDPYKDTAGPAVNPMIKITNIVAILLLAALAHGAA

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 71686; Mature: 71686

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVLIAIACGLLAVLYGFITSRQVLSASAGNEKMQEIAGAIQEGAKAYLGRQYRTIAVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GVVVAVLVGVFLGPISATGFVIGAVLSGVAGYIGMNISVRANVRTAAAAQTGLQAGLTMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHH
FRAGAITGMLVAGLALLAISVFFWYLTGPGGFSVGGDDRTVVDALVALAFGASLISIFAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYVVT
HCCCHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
VGATMVLIALLLKGAGDMLLPLMTLPLLMGGVCIITSIIGTYFVRLGSGTNVMGAMYKGF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LVTAILSIPAIWFATQYALGDMNAEIAGTGFNGRALFYCSLLGLVITGLIIWITEYYTGT
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
NYRPVRSIAKASETGHGTNVIQGLAVSLESTALPTLVICVGIIVAYQVAGIIGIAFGATA
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLALAGMVVALDAYGPVTDNAGGIAEMAGLDDSVREKTDLLDAVGNTTKAVTKGYAIGSA
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCHH
GLAALVLFGTYTADITEYSAELGLDAPLTFSLSSPYVIVGLLLGALLPYLFGAMGMTAVG
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RAAGDVVKDVRDQFANNKGIMDGTSRPDYARTVDLVTKAAIKEMIVPSLLPVLAPIVVYF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILWVAGPAAALEALGALLLGVIVGGLFVAISMTSGGGAWDNAKKYIEDGNHGGKGSEAH
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCCCCCC
KAAVTGDTVGDPYKDTAGPAVNPMIKITNIVAILLLAALAHGAA
HHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPVLIAIACGLLAVLYGFITSRQVLSASAGNEKMQEIAGAIQEGAKAYLGRQYRTIAVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GVVVAVLVGVFLGPISATGFVIGAVLSGVAGYIGMNISVRANVRTAAAAQTGLQAGLTMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHH
FRAGAITGMLVAGLALLAISVFFWYLTGPGGFSVGGDDRTVVDALVALAFGASLISIFAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYVVT
HCCCHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
VGATMVLIALLLKGAGDMLLPLMTLPLLMGGVCIITSIIGTYFVRLGSGTNVMGAMYKGF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LVTAILSIPAIWFATQYALGDMNAEIAGTGFNGRALFYCSLLGLVITGLIIWITEYYTGT
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
NYRPVRSIAKASETGHGTNVIQGLAVSLESTALPTLVICVGIIVAYQVAGIIGIAFGATA
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLALAGMVVALDAYGPVTDNAGGIAEMAGLDDSVREKTDLLDAVGNTTKAVTKGYAIGSA
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCHH
GLAALVLFGTYTADITEYSAELGLDAPLTFSLSSPYVIVGLLLGALLPYLFGAMGMTAVG
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RAAGDVVKDVRDQFANNKGIMDGTSRPDYARTVDLVTKAAIKEMIVPSLLPVLAPIVVYF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILWVAGPAAALEALGALLLGVIVGGLFVAISMTSGGGAWDNAKKYIEDGNHGGKGSEAH
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCCCCCC
KAAVTGDTVGDPYKDTAGPAVNPMIKITNIVAILLLAALAHGAA
HHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9630689; 11956221 [H]