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The map label for this gene is thiL [H]

Identifier: 103487507

GI number: 103487507

Start: 2136430

End: 2137383

Strand: Reverse

Name: thiL [H]

Synonym: Sala_2024

Alternate gene names: 103487507

Gene position: 2137383-2136430 (Counterclockwise)

Preceding gene: 103487508

Following gene: 103487506

Centisome position: 63.89

GC content: 70.02

Gene sequence:

>954_bases
ATGGCTATCCCCTACGCTTCCGCGATGACCGAAGCCGATTTCATCGCCCGCCTGCGCGCCATCGCGACCGATCCCGCCGC
GCGCGGGCTCGCCGACGATGCTGCGGTGTGGGAAGGGCTGGTGCTCACCCACGACATGATCGTCGAGGGCGTTCATTTCC
TGCCCGACGACCGGCCGCAGGATGTTGCGTGGAAACTTGTTGCGGTGAACCTGTCCGACCTGGCGGCGAAGGGGGCGGCG
CCGGTCGGCGTGCTCGTCGGGTACAGCCTTGGCGACGCGGCGTGGGACGCGGGCTTTGTCGAGGGGCTCGATGGAGCGCT
GCGCCGCTTCGGGGTCGCCCTGCTCGGCGGCGACACGGTGCGCGCGCCCACGGGAACACCGCGCAGCTTCGGCCTCACCG
CCATCGGTCGGGCGCCCGAAGGCGGCGCGCCGACGCGCGGCGGCGCGCGGCCGGGCGACCAGATCTGGGTGACGGGGACG
ATCGGCAATGCCGGTCTGGGCCTCGCGATGCGGCTGGGGCAGGTCGAGCCGAACGAGACCTGCCTTGCCGCCTATTGCCG
GCCGCAGCCGCAGCTGACCTTTGGGCAGGCAGTGGCGCCGCATGTTCATGCGATGATGGACCTATCCGACGGACTGTTGA
TCGACGCACAGCGCATGGCGGCGGCGAGCGGGTGCGAACTGGGCATCATGATGGATGCGATCCCCCTGTCGGCGGCGCTG
CTGGCGGTGCGGCCCGATGTGCTCGACACGCGGCTCGCCGCAGCGACCGCGGGTGACGATTATCAGCTCTTGTTCGCGGC
CGTCCCCGCCGCGGCCGATGCGATCCGCGAAATTGCGGCCGGGCTGAATGTTGCCGTGACCGCAATCGGCCATGCGGGGG
TGGGCGAGGGGATCGTGCTGACACACCATGCAAAGCGTGTTGCGGTGCCCGATCGACCCGGATTCATGCACTGA

Upstream 100 bases:

>100_bases
GAGGGGCGGCAACGTCGGCGCCAAAGCCCCTCCGTCAGCGCTTCGCGCTGCCACCTCCCCATCGCTGCGCGACAGGGAGG
ATCGGTATCTTTTATATGGT

Downstream 100 bases:

>100_bases
CGACCGGAGCCCGTCCGAATCGTCATCCCGCCTTTCGCCGCGATGACGTTCTGAGGCGAGGTTACGCAAATGGGCCGAAT
AACCGGGCTTGCCCTTGGCT

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MAIPYASAMTEADFIARLRAIATDPAARGLADDAAVWEGLVLTHDMIVEGVHFLPDDRPQDVAWKLVAVNLSDLAAKGAA
PVGVLVGYSLGDAAWDAGFVEGLDGALRRFGVALLGGDTVRAPTGTPRSFGLTAIGRAPEGGAPTRGGARPGDQIWVTGT
IGNAGLGLAMRLGQVEPNETCLAAYCRPQPQLTFGQAVAPHVHAMMDLSDGLLIDAQRMAAASGCELGIMMDAIPLSAAL
LAVRPDVLDTRLAAATAGDDYQLLFAAVPAAADAIREIAAGLNVAVTAIGHAGVGEGIVLTHHAKRVAVPDRPGFMH

Sequences:

>Translated_317_residues
MAIPYASAMTEADFIARLRAIATDPAARGLADDAAVWEGLVLTHDMIVEGVHFLPDDRPQDVAWKLVAVNLSDLAAKGAA
PVGVLVGYSLGDAAWDAGFVEGLDGALRRFGVALLGGDTVRAPTGTPRSFGLTAIGRAPEGGAPTRGGARPGDQIWVTGT
IGNAGLGLAMRLGQVEPNETCLAAYCRPQPQLTFGQAVAPHVHAMMDLSDGLLIDAQRMAAASGCELGIMMDAIPLSAAL
LAVRPDVLDTRLAAATAGDDYQLLFAAVPAAADAIREIAAGLNVAVTAIGHAGVGEGIVLTHHAKRVAVPDRPGFMH
>Mature_316_residues
AIPYASAMTEADFIARLRAIATDPAARGLADDAAVWEGLVLTHDMIVEGVHFLPDDRPQDVAWKLVAVNLSDLAAKGAAP
VGVLVGYSLGDAAWDAGFVEGLDGALRRFGVALLGGDTVRAPTGTPRSFGLTAIGRAPEGGAPTRGGARPGDQIWVTGTI
GNAGLGLAMRLGQVEPNETCLAAYCRPQPQLTFGQAVAPHVHAMMDLSDGLLIDAQRMAAASGCELGIMMDAIPLSAALL
AVRPDVLDTRLAAATAGDDYQLLFAAVPAAADAIREIAAGLNVAVTAIGHAGVGEGIVLTHHAKRVAVPDRPGFMH

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=321, Percent_Identity=35.202492211838, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 32543; Mature: 32411

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPYASAMTEADFIARLRAIATDPAARGLADDAAVWEGLVLTHDMIVEGVHFLPDDRPQ
CCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DVAWKLVAVNLSDLAAKGAAPVGVLVGYSLGDAAWDAGFVEGLDGALRRFGVALLGGDTV
CEEEEEEEEEHHHHHHCCCCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHCEEEECCCEE
RAPTGTPRSFGLTAIGRAPEGGAPTRGGARPGDQIWVTGTIGNAGLGLAMRLGQVEPNET
ECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHEECCCCCCCC
CLAAYCRPQPQLTFGQAVAPHVHAMMDLSDGLLIDAQRMAAASGCELGIMMDAIPLSAAL
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCEEEEEEHHHHHHHH
LAVRPDVLDTRLAAATAGDDYQLLFAAVPAAADAIREIAAGLNVAVTAIGHAGVGEGIVL
HHCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEE
THHAKRVAVPDRPGFMH
EECCCEEECCCCCCCCC
>Mature Secondary Structure 
AIPYASAMTEADFIARLRAIATDPAARGLADDAAVWEGLVLTHDMIVEGVHFLPDDRPQ
CCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DVAWKLVAVNLSDLAAKGAAPVGVLVGYSLGDAAWDAGFVEGLDGALRRFGVALLGGDTV
CEEEEEEEEEHHHHHHCCCCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHCEEEECCCEE
RAPTGTPRSFGLTAIGRAPEGGAPTRGGARPGDQIWVTGTIGNAGLGLAMRLGQVEPNET
ECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHEECCCCCCCC
CLAAYCRPQPQLTFGQAVAPHVHAMMDLSDGLLIDAQRMAAASGCELGIMMDAIPLSAAL
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCEEEEEEHHHHHHHH
LAVRPDVLDTRLAAATAGDDYQLLFAAVPAAADAIREIAAGLNVAVTAIGHAGVGEGIVL
HHCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEE
THHAKRVAVPDRPGFMH
EECCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]