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The map label for this gene is cheA [H]

Identifier: 103487225

GI number: 103487225

Start: 1831709

End: 1834132

Strand: Reverse

Name: cheA [H]

Synonym: Sala_1740

Alternate gene names: 103487225

Gene position: 1834132-1831709 (Counterclockwise)

Preceding gene: 103487226

Following gene: 103487224

Centisome position: 54.83

GC content: 69.18

Gene sequence:

>2424_bases
TTGCTGGGGCGCACCGATACGGCGATGGACGATCTACTGAACGAGTTTCTGGCCGAGACGGCCGAAATCCTGTCCGATGC
GGGCGGGGCGATCGTGGCGTGGGAGGCCGACCCTGCCGACCGCGCGCAGCTCGACGCCATTTTCCGCCTCGTCCACACGA
TCAAGGGCAGCTCGGGCTTTCTGGCGCTACCGCGCGTCACCGCGCTGGCGCACGCCGCCGAGGATGCGCTCGACCAGGTG
CGCCGCGGCCACCGCGCCGCCGACGCCGCGCTCGTGTCGGGCGTGCTGGCGGTTATCGACCGGCTCAACGCGCTATGTGT
AACGCTCGGGCAGGACGGCACCGAACCGGTCGGTGACGACCGCGACGTCATCGGCGCGCTGTCGCCGCGGGAGGAGCAAG
CGTCCGCGCCCGCGCCCGTCCAGGTTGCGGGCGTTCCCATGCGCCGTGAGGAGGATGTCGGTGCCGACCCCAACGGGTGG
CGGTCGATCCGCGTGCCGTTGCCCTTGCTCGACAGCGTGATGACCGGCGTCACCGACATCGTGCTGGCGCGCAACGAATT
TGCGCGAATGCTGCGCGAATCGGGCGCCGACAGCGCGACGATCGCGGCGTTCGATCGCCTGTCCGATTCGATCGCGGCGA
TGCGCCAGTCGGTCAGCCAGATGCGGATGCAGCGCATCGACAAATTGTTCGCGCCGCTGCCGCGCATCGTCCGCGACCTG
GCGCAGGAACTGGGCAAGAAGATCGCGTTCCAGACGAGCGGCGGCGAAGTCGAACTCGACCGCGAAATGATGGAGAATAT
CCGCGATCCGCTGATCCACATCGTGCGCAACGCGATCGACCATGGTATCGAGACGCTTGACGATCGCGTCGCCGCCGGAA
AGGATATCACCGCGACGATTTCGGTCGCGGCGCGCCAGTCGGGCAACCAGATCGAGATCGAGGTGCGCGACGACGGCCGC
GGGCTGTCGCCCGAGGCACTGGTCGCCAAGGCGGTCGCGTCGCGCCTGCTGACCGCAGCCGACGCCCGCGCGCTGTCGCC
CAGGGAAAAGCTCGAACTCATCTTCCGCCCCGGATTTTCGACCGCCGCAAAGGTTACCGAGGTTTCGGGCCGCGGGGTGG
GCATGGACATCGTCAAGGCGAATGTCGAGAAGATCGGGGGAGTCGTCGACATACGCAATGACGAAGGCCGCGGGCTGGCC
ATCCTGTTGCGCGTGCCGATGACGCTGACGATCATATCGGGGCTGATGGTGCGCGCGGCGGGGCAGTATTTCGCGATCCC
GCGCGGCGCGGTGCGCGAAGTCCTGCTCGAAAGCGGCGATACGGTCCGCATCGACCGCGTCGGCGGCGGCGAGCTGGCGA
CCGTGCGCGGCGAGCAATTTCCGCTGCTGCGCCTCGAAAACCTCCTCGGCTGCGCGCGTGCCGCGGATGACGGGGAAGAC
GACCGCGCGCTGGTGATCGTGCGGCCGGGGCAGGGACAGAGCTATGCGCTGAGCGTCGCGGCGATCCACGACCATGAGGA
GCTGGTGATCAAGCCGGCGGCGCCGATGATCATGGCGACGGGACTTTATGCGGGCACGACGCTGCCCGACAACGGTCGCC
CGGTCCTCCTCCTCGACGTCCAGGGGCTGCTTGCGGTCGCCGGGGTCGATGCGAGCGAAGCCGGGCGCAGCAAGGACGGG
CTGGCCGACGCCGAAGCCGAGGCGGCCGCGACGCGCGATGCGACGCAGCTGTTGCTGTTCCGCGACATGGACGAGCGGGT
GCGCGGCATCCGCCTGTCGGTGATCGAGCGCGTCGAGGACGTCCCGCTCCCGGCACTTTTCGAAAGCGCCGGTCGCGTGC
AGGCAAAGATCGGCGAAGAGATTTTCCCGGTCCACGCCGCCCGGCCGCCGGTCGGGACGGGCCATATCAAGCTCCTCCGC
CTCCACGACGGCCGTTCGGTGCTCTGCTACCCGATCGCCGAGGTCATCGACATCGTCCGCCTGCCCGATGCGATCCAGCC
GTCGGGCGTGCCGGGGCTGATCGCGGGCGTCGTGCTGATCGGCGGCGCGCCGGTCGAACTGATCGACCCCTTCTGGCTGA
TGGAGCAACAGGCCGCCCGATCGCTCCCGCTGCCGCGGCGCGAACCGCTGTGTCACCTTGCCGACGACCATGACGGCTGG
GGCGTCAATTTCCTGGCGCCGATCCTGCGCGGCGCCGGATATCGCGTCACGCTGGCGGCCGAGACCGCCGACGAAACCCC
CGACCTGCTGCTCTGCCTGTCCGACGACGGCGAGTTGTGCGGCCATGCCGCGGGCGATGTGCCCATGATCCGCCTGCGAT
CCTCGATCGAGGCGGCGGCGCCCGACGACCAGAGCGTCTATCGTTACGACCGCGAAGCGCTGCTTGCCGCGATGCGCCGC
CGCGTCGGAGGAGCGCGGCCATGA

Upstream 100 bases:

>100_bases
CTGGCGCGCGAAACGCCGACCTCGCTGCTCGTCGGCGCGGTGCTGCGCGCGCGCGGGTAAAGCCACTTTTAACCATTGCC
CGCCATGGTGGCGTCTCAAG

Downstream 100 bases:

>100_bases
TGGACAAACTCTATCTGATCGCGCGCATCGCCGACACGCGCGTCGCGCTGCGCAGCCGCGCGATCCATTCGGTGGTGACT
GTCGGCACGCCGGTCGAGGT

Product: CheA signal transduction histidine kinases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 807; Mature: 807

Protein sequence:

>807_residues
MLGRTDTAMDDLLNEFLAETAEILSDAGGAIVAWEADPADRAQLDAIFRLVHTIKGSSGFLALPRVTALAHAAEDALDQV
RRGHRAADAALVSGVLAVIDRLNALCVTLGQDGTEPVGDDRDVIGALSPREEQASAPAPVQVAGVPMRREEDVGADPNGW
RSIRVPLPLLDSVMTGVTDIVLARNEFARMLRESGADSATIAAFDRLSDSIAAMRQSVSQMRMQRIDKLFAPLPRIVRDL
AQELGKKIAFQTSGGEVELDREMMENIRDPLIHIVRNAIDHGIETLDDRVAAGKDITATISVAARQSGNQIEIEVRDDGR
GLSPEALVAKAVASRLLTAADARALSPREKLELIFRPGFSTAAKVTEVSGRGVGMDIVKANVEKIGGVVDIRNDEGRGLA
ILLRVPMTLTIISGLMVRAAGQYFAIPRGAVREVLLESGDTVRIDRVGGGELATVRGEQFPLLRLENLLGCARAADDGED
DRALVIVRPGQGQSYALSVAAIHDHEELVIKPAAPMIMATGLYAGTTLPDNGRPVLLLDVQGLLAVAGVDASEAGRSKDG
LADAEAEAAATRDATQLLLFRDMDERVRGIRLSVIERVEDVPLPALFESAGRVQAKIGEEIFPVHAARPPVGTGHIKLLR
LHDGRSVLCYPIAEVIDIVRLPDAIQPSGVPGLIAGVVLIGGAPVELIDPFWLMEQQAARSLPLPRREPLCHLADDHDGW
GVNFLAPILRGAGYRVTLAAETADETPDLLLCLSDDGELCGHAAGDVPMIRLRSSIEAAAPDDQSVYRYDREALLAAMRR
RVGGARP

Sequences:

>Translated_807_residues
MLGRTDTAMDDLLNEFLAETAEILSDAGGAIVAWEADPADRAQLDAIFRLVHTIKGSSGFLALPRVTALAHAAEDALDQV
RRGHRAADAALVSGVLAVIDRLNALCVTLGQDGTEPVGDDRDVIGALSPREEQASAPAPVQVAGVPMRREEDVGADPNGW
RSIRVPLPLLDSVMTGVTDIVLARNEFARMLRESGADSATIAAFDRLSDSIAAMRQSVSQMRMQRIDKLFAPLPRIVRDL
AQELGKKIAFQTSGGEVELDREMMENIRDPLIHIVRNAIDHGIETLDDRVAAGKDITATISVAARQSGNQIEIEVRDDGR
GLSPEALVAKAVASRLLTAADARALSPREKLELIFRPGFSTAAKVTEVSGRGVGMDIVKANVEKIGGVVDIRNDEGRGLA
ILLRVPMTLTIISGLMVRAAGQYFAIPRGAVREVLLESGDTVRIDRVGGGELATVRGEQFPLLRLENLLGCARAADDGED
DRALVIVRPGQGQSYALSVAAIHDHEELVIKPAAPMIMATGLYAGTTLPDNGRPVLLLDVQGLLAVAGVDASEAGRSKDG
LADAEAEAAATRDATQLLLFRDMDERVRGIRLSVIERVEDVPLPALFESAGRVQAKIGEEIFPVHAARPPVGTGHIKLLR
LHDGRSVLCYPIAEVIDIVRLPDAIQPSGVPGLIAGVVLIGGAPVELIDPFWLMEQQAARSLPLPRREPLCHLADDHDGW
GVNFLAPILRGAGYRVTLAAETADETPDLLLCLSDDGELCGHAAGDVPMIRLRSSIEAAAPDDQSVYRYDREALLAAMRR
RVGGARP
>Mature_807_residues
MLGRTDTAMDDLLNEFLAETAEILSDAGGAIVAWEADPADRAQLDAIFRLVHTIKGSSGFLALPRVTALAHAAEDALDQV
RRGHRAADAALVSGVLAVIDRLNALCVTLGQDGTEPVGDDRDVIGALSPREEQASAPAPVQVAGVPMRREEDVGADPNGW
RSIRVPLPLLDSVMTGVTDIVLARNEFARMLRESGADSATIAAFDRLSDSIAAMRQSVSQMRMQRIDKLFAPLPRIVRDL
AQELGKKIAFQTSGGEVELDREMMENIRDPLIHIVRNAIDHGIETLDDRVAAGKDITATISVAARQSGNQIEIEVRDDGR
GLSPEALVAKAVASRLLTAADARALSPREKLELIFRPGFSTAAKVTEVSGRGVGMDIVKANVEKIGGVVDIRNDEGRGLA
ILLRVPMTLTIISGLMVRAAGQYFAIPRGAVREVLLESGDTVRIDRVGGGELATVRGEQFPLLRLENLLGCARAADDGED
DRALVIVRPGQGQSYALSVAAIHDHEELVIKPAAPMIMATGLYAGTTLPDNGRPVLLLDVQGLLAVAGVDASEAGRSKDG
LADAEAEAAATRDATQLLLFRDMDERVRGIRLSVIERVEDVPLPALFESAGRVQAKIGEEIFPVHAARPPVGTGHIKLLR
LHDGRSVLCYPIAEVIDIVRLPDAIQPSGVPGLIAGVVLIGGAPVELIDPFWLMEQQAARSLPLPRREPLCHLADDHDGW
GVNFLAPILRGAGYRVTLAAETADETPDLLLCLSDDGELCGHAAGDVPMIRLRSSIEAAAPDDQSVYRYDREALLAAMRR
RVGGARP

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=405, Percent_Identity=37.2839506172839, Blast_Score=225, Evalue=9e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86246; Mature: 86246

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGRTDTAMDDLLNEFLAETAEILSDAGGAIVAWEADPADRAQLDAIFRLVHTIKGSSGF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
LALPRVTALAHAAEDALDQVRRGHRAADAALVSGVLAVIDRLNALCVTLGQDGTEPVGDD
EEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
RDVIGALSPREEQASAPAPVQVAGVPMRREEDVGADPNGWRSIRVPLPLLDSVMTGVTDI
CHHHCCCCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHH
VLARNEFARMLRESGADSATIAAFDRLSDSIAAMRQSVSQMRMQRIDKLFAPLPRIVRDL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQELGKKIAFQTSGGEVELDREMMENIRDPLIHIVRNAIDHGIETLDDRVAAGKDITATI
HHHHHHHEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
SVAARQSGNQIEIEVRDDGRGLSPEALVAKAVASRLLTAADARALSPREKLELIFRPGFS
EEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCC
TAAKVTEVSGRGVGMDIVKANVEKIGGVVDIRNDEGRGLAILLRVPMTLTIISGLMVRAA
CHHHHEECCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHC
GQYFAIPRGAVREVLLESGDTVRIDRVGGGELATVRGEQFPLLRLENLLGCARAADDGED
CCEEECCHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCC
DRALVIVRPGQGQSYALSVAAIHDHEELVIKPAAPMIMATGLYAGTTLPDNGRPVLLLDV
CCEEEEEECCCCCCEEEEEEEEECCCEEEEECCCCHHEECCCCCCCCCCCCCCEEEEEEC
QGLLAVAGVDASEAGRSKDGLADAEAEAAATRDATQLLLFRDMDERVRGIRLSVIERVED
CCHHHEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC
VPLPALFESAGRVQAKIGEEIFPVHAARPPVGTGHIKLLRLHDGRSVLCYPIAEVIDIVR
CCCHHHHHHCCCHHHHHCCHHEECCCCCCCCCCCCEEEEEEECCCEEEEHHHHHHHHHHH
LPDAIQPSGVPGLIAGVVLIGGAPVELIDPFWLMEQQAARSLPLPRREPLCHLADDHDGW
CCCCCCCCCCCHHHHHHHHCCCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCEECCCCCCC
GVNFLAPILRGAGYRVTLAAETADETPDLLLCLSDDGELCGHAAGDVPMIRLRSSIEAAA
CHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCC
PDDQSVYRYDREALLAAMRRRVGGARP
CCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLGRTDTAMDDLLNEFLAETAEILSDAGGAIVAWEADPADRAQLDAIFRLVHTIKGSSGF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
LALPRVTALAHAAEDALDQVRRGHRAADAALVSGVLAVIDRLNALCVTLGQDGTEPVGDD
EEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
RDVIGALSPREEQASAPAPVQVAGVPMRREEDVGADPNGWRSIRVPLPLLDSVMTGVTDI
CHHHCCCCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHH
VLARNEFARMLRESGADSATIAAFDRLSDSIAAMRQSVSQMRMQRIDKLFAPLPRIVRDL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQELGKKIAFQTSGGEVELDREMMENIRDPLIHIVRNAIDHGIETLDDRVAAGKDITATI
HHHHHHHEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
SVAARQSGNQIEIEVRDDGRGLSPEALVAKAVASRLLTAADARALSPREKLELIFRPGFS
EEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCC
TAAKVTEVSGRGVGMDIVKANVEKIGGVVDIRNDEGRGLAILLRVPMTLTIISGLMVRAA
CHHHHEECCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHC
GQYFAIPRGAVREVLLESGDTVRIDRVGGGELATVRGEQFPLLRLENLLGCARAADDGED
CCEEECCHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCC
DRALVIVRPGQGQSYALSVAAIHDHEELVIKPAAPMIMATGLYAGTTLPDNGRPVLLLDV
CCEEEEEECCCCCCEEEEEEEEECCCEEEEECCCCHHEECCCCCCCCCCCCCCEEEEEEC
QGLLAVAGVDASEAGRSKDGLADAEAEAAATRDATQLLLFRDMDERVRGIRLSVIERVED
CCHHHEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC
VPLPALFESAGRVQAKIGEEIFPVHAARPPVGTGHIKLLRLHDGRSVLCYPIAEVIDIVR
CCCHHHHHHCCCHHHHHCCHHEECCCCCCCCCCCCEEEEEEECCCEEEEHHHHHHHHHHH
LPDAIQPSGVPGLIAGVVLIGGAPVELIDPFWLMEQQAARSLPLPRREPLCHLADDHDGW
CCCCCCCCCCCHHHHHHHHCCCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCEECCCCCCC
GVNFLAPILRGAGYRVTLAAETADETPDLLLCLSDDGELCGHAAGDVPMIRLRSSIEAAA
CHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCC
PDDQSVYRYDREALLAAMRRRVGGARP
CCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]