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The map label for this gene is ptmB [H]

Identifier: 103487066

GI number: 103487066

Start: 1654644

End: 1655327

Strand: Reverse

Name: ptmB [H]

Synonym: Sala_1581

Alternate gene names: 103487066

Gene position: 1655327-1654644 (Counterclockwise)

Preceding gene: 103487067

Following gene: 103487065

Centisome position: 49.48

GC content: 62.87

Gene sequence:

>684_bases
ATGTCGGTTCTGGCGATCATTCCGGCCCGTGGCGGGTCAAAGGGCGTGCCCGGAAAGAATCTGCGGTTGCTGGCTGGCAA
GCCCTTGATCTCGTGGAGCATCGAGCAGGCGCTCGCCGCACATGGCGTTACCGACGTCGTCGTGTCCACGGACGCGGAGG
ACATCGCGGCTGTCGCCCGGTCCTTTGGCGCCCAGGTGCCGTTCCTGCGTCCGGCCGAACTGGCGACGGACACAGCTCCA
ACCGAGCCGGTGATGCTCCATACGCTTGAGCGGATGGAGGCGATGAAGGGCCGGTATGAGGCGATCCTGCTGCTTCAGCC
AACCTCCCCGCTTCGCTTGCCGGGGACGATCGACGGCGCGCTGCACGCCTTCGCGGCGGAGGGGGCCGACAGCCTGCTCG
GGGTTGTCGAAAGTCACGCCTTCTTCTGGCAGGCGGACCCCGTCCGTGCATCCTATGACTACACAAACCGCCCGCGGCGC
CAGGATATTGCGGAAGCCGATCGTCATTATCGCGAAACGGGCTCCATCTATCTGACCAGGCGGGACATTTTTATGGAAAA
ATGCAACCGCCTGGCAGGTCGCATCGCCTTGTACCGGATGCAGGAATGCGAAGGCTGGGAAATCGACACCGAAATCGACT
TCGAGATCGTCGAAGCGCTGATGAAGCAGGAACTCTCCACGTGA

Upstream 100 bases:

>100_bases
TCATTCTGGGGATTGGAGCCGAACTCGACTCTGCAGCCGCGCTGATCGACTCAGTAACGCTGTCTCGCACCCCGGCTCGC
GTTGCGGGCCCAGGGTCCTG

Downstream 100 bases:

>100_bases
TCATTGAACGGAATATTGCACCGCTGATCGTCTTTGCCGAGGAAGACATTGTTTCGGCGCTTCGCAAGATCAGCGTCAAT
CAGCGCGGCTTTGTCCTGTG

Product: acylneuraminate cytidylyltransferase

Products: diphosphate; CMP-N-acylneuraminate

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSVLAIIPARGGSKGVPGKNLRLLAGKPLISWSIEQALAAHGVTDVVVSTDAEDIAAVARSFGAQVPFLRPAELATDTAP
TEPVMLHTLERMEAMKGRYEAILLLQPTSPLRLPGTIDGALHAFAAEGADSLLGVVESHAFFWQADPVRASYDYTNRPRR
QDIAEADRHYRETGSIYLTRRDIFMEKCNRLAGRIALYRMQECEGWEIDTEIDFEIVEALMKQELST

Sequences:

>Translated_227_residues
MSVLAIIPARGGSKGVPGKNLRLLAGKPLISWSIEQALAAHGVTDVVVSTDAEDIAAVARSFGAQVPFLRPAELATDTAP
TEPVMLHTLERMEAMKGRYEAILLLQPTSPLRLPGTIDGALHAFAAEGADSLLGVVESHAFFWQADPVRASYDYTNRPRR
QDIAEADRHYRETGSIYLTRRDIFMEKCNRLAGRIALYRMQECEGWEIDTEIDFEIVEALMKQELST
>Mature_226_residues
SVLAIIPARGGSKGVPGKNLRLLAGKPLISWSIEQALAAHGVTDVVVSTDAEDIAAVARSFGAQVPFLRPAELATDTAPT
EPVMLHTLERMEAMKGRYEAILLLQPTSPLRLPGTIDGALHAFAAEGADSLLGVVESHAFFWQADPVRASYDYTNRPRRQ
DIAEADRHYRETGSIYLTRRDIFMEKCNRLAGRIALYRMQECEGWEIDTEIDFEIVEALMKQELST

Specific function: Required for biosynthesis of LAH modification in the post-translational modification of Campylobacter coli flagellin [H]

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=221, Percent_Identity=35.2941176470588, Blast_Score=110, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: 2.7.7.43

Molecular weight: Translated: 25083; Mature: 24952

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLAIIPARGGSKGVPGKNLRLLAGKPLISWSIEQALAAHGVTDVVVSTDAEDIAAVAR
CCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
SFGAQVPFLRPAELATDTAPTEPVMLHTLERMEAMKGRYEAILLLQPTSPLRLPGTIDGA
HHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHH
LHAFAAEGADSLLGVVESHAFFWQADPVRASYDYTNRPRRQDIAEADRHYRETGSIYLTR
HHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEH
RDIFMEKCNRLAGRIALYRMQECEGWEIDTEIDFEIVEALMKQELST
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLAIIPARGGSKGVPGKNLRLLAGKPLISWSIEQALAAHGVTDVVVSTDAEDIAAVAR
CEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
SFGAQVPFLRPAELATDTAPTEPVMLHTLERMEAMKGRYEAILLLQPTSPLRLPGTIDGA
HHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHH
LHAFAAEGADSLLGVVESHAFFWQADPVRASYDYTNRPRRQDIAEADRHYRETGSIYLTR
HHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEH
RDIFMEKCNRLAGRIALYRMQECEGWEIDTEIDFEIVEALMKQELST
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; N-acylneuraminate

Specific reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8825781 [H]