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The map label for this gene is gutQ [C]

Identifier: 103487065

GI number: 103487065

Start: 1652398

End: 1654647

Strand: Reverse

Name: gutQ [C]

Synonym: Sala_1580

Alternate gene names: 103487065

Gene position: 1654647-1652398 (Counterclockwise)

Preceding gene: 103487066

Following gene: 103487064

Centisome position: 49.46

GC content: 59.33

Gene sequence:

>2250_bases
GTGATCATTGAACGGAATATTGCACCGCTGATCGTCTTTGCCGAGGAAGACATTGTTTCGGCGCTTCGCAAGATCAGCGT
CAATCAGCGCGGCTTTGTCCTGTGTGTTTCGGCGTCGGGAAAGCTTGAAGCCGTGCTGACTGACGGCGATGTGCGCCGTT
GGCTGGTCGACGGCGGCCAGTTCGATTTCGGCGTCAGCGCGGCAATGGTCGCGAACAAGCAGTTTGTCGCTGCAAAGGAT
GGAGCCAGCGAGGACGAGCTGAACGATCTTTTTTCGGATCGGGTGACATTCGTTCCCATCGTCGACGGGCAACGTCATCT
GCGCGCCGTCGCCTTCAGGGGGCAGCCGGTGGTGCGGATCGGCGACCGGGTGATAGGCCCGGAGAGTCCGGCCTACATTA
TTGCCGAGATCGGCAATAATCACAACGGCAGCATCGAACTCGCCAAGCGGCTGGTCGAGCTTGCCGTCGAGGCAGGCGCC
GACTGCGCAAAGTTCCAGATGCGCGACATGTCGAGCCTGTATCGCAATGAGGGCGATTCCGATGACGCCAGCGCGGACCT
CGGGGCGCAATATACGCTGGATCTCCTCTCGCGCTTTCAGCTGCCCGTCGATGAAATGTTCCAGGTGTTCGATTATTGCC
ATGAACTGGGTATCCAGCCGTTATGCACGCCCTGGGATGAAGCCAGTCTGGCCCGGCTGGAAGCCTATGACATGCCGGCA
TACAAGCTGGCTTCGGCCGATCTGACCAATCACCCGTTGTTGAGCGCGATGGCGCGAACGGGAAAGACGCTGATCTGTTC
GACCGGCATGTCGACCCAAGGCGAGATCGAAAACGCGATTGCCGTCCTGAAGCGCCACACGGCGCCCTATGTTCTGCTGC
ATTGCAATTCGACCTATCCGGCGCCGTTCAAGGATATTAATCTGGCCTATATCCGCAGGTTGGAGAAACTTTCGGGCGGG
GTTGTCGGATATTCGGGGCACGAGCGGGGATATTTCATTCCCGTGGCGGCCGTCGCGATGGGGGCAAAGGTTATAGAGAA
GCACTTTACCGTCGATCGGGGGATGGAAGGAAATGATCATCGGGTCAGCCTGCTGCCCGACGAGTTCTCGGCGATGGTGC
GCGCCATCCGCGAAGTCGAGGAGGCCATGGGTTATGGTGGCGCGCGCGGCATCACCCAGGGTGAAATGATGAATCGCGAA
GTCCTGGCAAAGAGTCTGGTTGCCGCGCGGCCGATCCGGGCGGGGCAGCAGATTGCCGACGAGGACATCCAGATCCGCAG
TCCGGGCCAGGGGCTGCAACCCTATTTTCGTGCCGAGCTGGTCGGACGGATCGCAAAGCGGGATATGATAGAGGGAGATT
TTTTCTTCCAGAGCGACCTCGCGGACGCGGTCGCCAGCGCGCGTGATTACCGGTTCGACCGCCCTTTCGGCGTGCCTGTG
CGCTACCATGACCTGCAGAAGATGATCGGCGCCACCAATCTCGATCTTGTCGAGTTCCATCTGAGCTACAAGGACATGGA
GCTGGATCCGGTCCGGATGCTGGACGGCGCAACGTTCGATATTGCGCTCGTTGTGCATAGTCCCGAACTGTTTGCCGGCG
ACCATATCATGGATCTGTGTTCGGAGGATGATGTCTATCGCCAGCGTTCGATCGACGAATTGCAGCGCGTGATTGACATC
ACACGGACGCTGAAACCCCATTTCACGAAATCGGCTCGTCCGCCGATCATCATCAACGCGGGCGGATTTTCCGCGGACGG
TCCGATTACCGCGGAACGGCGACCTGCGATGTATGACCGCATCGCCGATGCCCTGTCGCGGCTCGACAAGGAAGGGGTGG
AGATAATTCCGCAGACGATGCCGCCCTATCCGTGGCATTTCGGTGGGCAGCGCTACCATAACCTCTTCCTGTCCGCAGAG
GACATCGTGCGTTTCTGTTCGGAACATGGATACCGGATTTGCCTCGACGTGTCGCATTCGGCGCTGGCGGCGACGCATCT
GAAGACCAGTTTTCAGGAACTTCTGCGACAGGTTGGGCCGTACACATGCCATATGCATATCGTTGATGCAGCGGGGGTCG
ACGGCGAAGGCCTGCAGATCGGCGATGGCACGGTCGATTTCGCCATGGTCGCCGATGTCCTGCGCGAAACGGCGCCCGAT
GCCAGCTTCATTCCTGAGATATGGCAAGGGCACAAGGATGACGGCGCAGGTTTCTGGCAGGCGCTCGACCGTCTCGAACA
ATGGTTCTGA

Upstream 100 bases:

>100_bases
GCATCGCCTTGTACCGGATGCAGGAATGCGAAGGCTGGGAAATCGACACCGAAATCGACTTCGAGATCGTCGAAGCGCTG
ATGAAGCAGGAACTCTCCAC

Downstream 100 bases:

>100_bases
CCGATGCCGGGCCGCCGCGATGCCTTGTCATCGGGACAGGGTCGATCGGTCGGCGGCATGTGGCAAATCTGAAGAAACTG
GCCCCCGGTGCGCAACTGGC

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MIIERNIAPLIVFAEEDIVSALRKISVNQRGFVLCVSASGKLEAVLTDGDVRRWLVDGGQFDFGVSAAMVANKQFVAAKD
GASEDELNDLFSDRVTFVPIVDGQRHLRAVAFRGQPVVRIGDRVIGPESPAYIIAEIGNNHNGSIELAKRLVELAVEAGA
DCAKFQMRDMSSLYRNEGDSDDASADLGAQYTLDLLSRFQLPVDEMFQVFDYCHELGIQPLCTPWDEASLARLEAYDMPA
YKLASADLTNHPLLSAMARTGKTLICSTGMSTQGEIENAIAVLKRHTAPYVLLHCNSTYPAPFKDINLAYIRRLEKLSGG
VVGYSGHERGYFIPVAAVAMGAKVIEKHFTVDRGMEGNDHRVSLLPDEFSAMVRAIREVEEAMGYGGARGITQGEMMNRE
VLAKSLVAARPIRAGQQIADEDIQIRSPGQGLQPYFRAELVGRIAKRDMIEGDFFFQSDLADAVASARDYRFDRPFGVPV
RYHDLQKMIGATNLDLVEFHLSYKDMELDPVRMLDGATFDIALVVHSPELFAGDHIMDLCSEDDVYRQRSIDELQRVIDI
TRTLKPHFTKSARPPIIINAGGFSADGPITAERRPAMYDRIADALSRLDKEGVEIIPQTMPPYPWHFGGQRYHNLFLSAE
DIVRFCSEHGYRICLDVSHSALAATHLKTSFQELLRQVGPYTCHMHIVDAAGVDGEGLQIGDGTVDFAMVADVLRETAPD
ASFIPEIWQGHKDDGAGFWQALDRLEQWF

Sequences:

>Translated_749_residues
MIIERNIAPLIVFAEEDIVSALRKISVNQRGFVLCVSASGKLEAVLTDGDVRRWLVDGGQFDFGVSAAMVANKQFVAAKD
GASEDELNDLFSDRVTFVPIVDGQRHLRAVAFRGQPVVRIGDRVIGPESPAYIIAEIGNNHNGSIELAKRLVELAVEAGA
DCAKFQMRDMSSLYRNEGDSDDASADLGAQYTLDLLSRFQLPVDEMFQVFDYCHELGIQPLCTPWDEASLARLEAYDMPA
YKLASADLTNHPLLSAMARTGKTLICSTGMSTQGEIENAIAVLKRHTAPYVLLHCNSTYPAPFKDINLAYIRRLEKLSGG
VVGYSGHERGYFIPVAAVAMGAKVIEKHFTVDRGMEGNDHRVSLLPDEFSAMVRAIREVEEAMGYGGARGITQGEMMNRE
VLAKSLVAARPIRAGQQIADEDIQIRSPGQGLQPYFRAELVGRIAKRDMIEGDFFFQSDLADAVASARDYRFDRPFGVPV
RYHDLQKMIGATNLDLVEFHLSYKDMELDPVRMLDGATFDIALVVHSPELFAGDHIMDLCSEDDVYRQRSIDELQRVIDI
TRTLKPHFTKSARPPIIINAGGFSADGPITAERRPAMYDRIADALSRLDKEGVEIIPQTMPPYPWHFGGQRYHNLFLSAE
DIVRFCSEHGYRICLDVSHSALAATHLKTSFQELLRQVGPYTCHMHIVDAAGVDGEGLQIGDGTVDFAMVADVLRETAPD
ASFIPEIWQGHKDDGAGFWQALDRLEQWF
>Mature_749_residues
MIIERNIAPLIVFAEEDIVSALRKISVNQRGFVLCVSASGKLEAVLTDGDVRRWLVDGGQFDFGVSAAMVANKQFVAAKD
GASEDELNDLFSDRVTFVPIVDGQRHLRAVAFRGQPVVRIGDRVIGPESPAYIIAEIGNNHNGSIELAKRLVELAVEAGA
DCAKFQMRDMSSLYRNEGDSDDASADLGAQYTLDLLSRFQLPVDEMFQVFDYCHELGIQPLCTPWDEASLARLEAYDMPA
YKLASADLTNHPLLSAMARTGKTLICSTGMSTQGEIENAIAVLKRHTAPYVLLHCNSTYPAPFKDINLAYIRRLEKLSGG
VVGYSGHERGYFIPVAAVAMGAKVIEKHFTVDRGMEGNDHRVSLLPDEFSAMVRAIREVEEAMGYGGARGITQGEMMNRE
VLAKSLVAARPIRAGQQIADEDIQIRSPGQGLQPYFRAELVGRIAKRDMIEGDFFFQSDLADAVASARDYRFDRPFGVPV
RYHDLQKMIGATNLDLVEFHLSYKDMELDPVRMLDGATFDIALVVHSPELFAGDHIMDLCSEDDVYRQRSIDELQRVIDI
TRTLKPHFTKSARPPIIINAGGFSADGPITAERRPAMYDRIADALSRLDKEGVEIIPQTMPPYPWHFGGQRYHNLFLSAE
DIVRFCSEHGYRICLDVSHSALAATHLKTSFQELLRQVGPYTCHMHIVDAAGVDGEGLQIGDGTVDFAMVADVLRETAPD
ASFIPEIWQGHKDDGAGFWQALDRLEQWF

Specific function: Not Known. [C]

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=324, Percent_Identity=33.641975308642, Blast_Score=186, Evalue=8e-47,
Organism=Drosophila melanogaster, GI21357081, Length=339, Percent_Identity=34.2182890855457, Blast_Score=181, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 83051; Mature: 83051

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIERNIAPLIVFAEEDIVSALRKISVNQRGFVLCVSASGKLEAVLTDGDVRRWLVDGGQ
CEECCCCCCEEEEECHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCEEEEECCCC
FDFGVSAAMVANKQFVAAKDGASEDELNDLFSDRVTFVPIVDGQRHLRAVAFRGQPVVRI
CCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCCHHHEEEEECCCCEEEE
GDRVIGPESPAYIIAEIGNNHNGSIELAKRLVELAVEAGADCAKFQMRDMSSLYRNEGDS
CCEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
DDASADLGAQYTLDLLSRFQLPVDEMFQVFDYCHELGIQPLCTPWDEASLARLEAYDMPA
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCC
YKLASADLTNHPLLSAMARTGKTLICSTGMSTQGEIENAIAVLKRHTAPYVLLHCNSTYP
HHCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
APFKDINLAYIRRLEKLSGGVVGYSGHERGYFIPVAAVAMGAKVIEKHFTVDRGMEGNDH
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCC
RVSLLPDEFSAMVRAIREVEEAMGYGGARGITQGEMMNREVLAKSLVAARPIRAGQQIAD
EEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCC
EDIQIRSPGQGLQPYFRAELVGRIAKRDMIEGDFFFQSDLADAVASARDYRFDRPFGVPV
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCC
RYHDLQKMIGATNLDLVEFHLSYKDMELDPVRMLDGATFDIALVVHSPELFAGDHIMDLC
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHCCCCEEEEEEEECCCHHCCCHHHHHH
SEDDVYRQRSIDELQRVIDITRTLKPHFTKSARPPIIINAGGFSADGPITAERRPAMYDR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHH
IADALSRLDKEGVEIIPQTMPPYPWHFGGQRYHNLFLSAEDIVRFCSEHGYRICLDVSHS
HHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHEECHHHHHHHHHHCCCEEEEECCCH
ALAATHLKTSFQELLRQVGPYTCHMHIVDAAGVDGEGLQIGDGTVDFAMVADVLRETAPD
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHCCCC
ASFIPEIWQGHKDDGAGFWQALDRLEQWF
CCCCHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIIERNIAPLIVFAEEDIVSALRKISVNQRGFVLCVSASGKLEAVLTDGDVRRWLVDGGQ
CEECCCCCCEEEEECHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCEEEEECCCC
FDFGVSAAMVANKQFVAAKDGASEDELNDLFSDRVTFVPIVDGQRHLRAVAFRGQPVVRI
CCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCCHHHEEEEECCCCEEEE
GDRVIGPESPAYIIAEIGNNHNGSIELAKRLVELAVEAGADCAKFQMRDMSSLYRNEGDS
CCEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
DDASADLGAQYTLDLLSRFQLPVDEMFQVFDYCHELGIQPLCTPWDEASLARLEAYDMPA
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCC
YKLASADLTNHPLLSAMARTGKTLICSTGMSTQGEIENAIAVLKRHTAPYVLLHCNSTYP
HHCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCC
APFKDINLAYIRRLEKLSGGVVGYSGHERGYFIPVAAVAMGAKVIEKHFTVDRGMEGNDH
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCC
RVSLLPDEFSAMVRAIREVEEAMGYGGARGITQGEMMNREVLAKSLVAARPIRAGQQIAD
EEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCC
EDIQIRSPGQGLQPYFRAELVGRIAKRDMIEGDFFFQSDLADAVASARDYRFDRPFGVPV
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCC
RYHDLQKMIGATNLDLVEFHLSYKDMELDPVRMLDGATFDIALVVHSPELFAGDHIMDLC
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHCCCCEEEEEEEECCCHHCCCHHHHHH
SEDDVYRQRSIDELQRVIDITRTLKPHFTKSARPPIIINAGGFSADGPITAERRPAMYDR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHH
IADALSRLDKEGVEIIPQTMPPYPWHFGGQRYHNLFLSAEDIVRFCSEHGYRICLDVSHS
HHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHEECHHHHHHHHHHCCCEEEEECCCH
ALAATHLKTSFQELLRQVGPYTCHMHIVDAAGVDGEGLQIGDGTVDFAMVADVLRETAPD
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHCCCC
ASFIPEIWQGHKDDGAGFWQALDRLEQWF
CCCCHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]