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The map label for this gene is ugd [H]

Identifier: 103487048

GI number: 103487048

Start: 1632372

End: 1633565

Strand: Reverse

Name: ugd [H]

Synonym: Sala_1563

Alternate gene names: 103487048

Gene position: 1633565-1632372 (Counterclockwise)

Preceding gene: 103487049

Following gene: 103487047

Centisome position: 48.83

GC content: 61.06

Gene sequence:

>1194_bases
TTGACGTCAGCAAAGGATTCGCCCGTGAAGATCGCCGTCGTCGGCACGGGTTATGTCGGCATTTCGAACGCGGTTCTGCT
GGCGCAGCATAATGCGGTCGTCGCGCTCGACATCGACACGCGCAAGGTCGAGCTCGTCAACGCGCGGCAATCGCCGATCG
TCGATCCCGAGATCGAGGATTATCTGGCCAACAAGCAACTGAACCTGGTTGCGACCACCGACAAGCAGGCGGCCTATGCC
GACGCGAACTTCGTCATCGTTGCAACGCCGACCGACTATGATCCCGACACCAATTATTTCAACACGAACAGCGTCGAAAG
CGTCATCGCCGACGCGCTGAAGCTGGCGCCCGGCGCGCTGGTCGTCGTCAAATCGACCGTCCCGGTGGGCTTCACCGAAC
GGATGCGCGCCGAACATGGCAGCAACGACATCGTCTTTTCCCCGGAGTTCCTGCGCGAAGGGCGCGCGCTCCACGACAAT
CTCCATCCGTCGCGGATCATCGTCGGCAACACGCACCCGCGCGCCGCCGATTTCGCGCGGCTGTTGCTCGAAGGGTCGCT
GAAGCCCGATACGGCCGTTCTCCAGACGGGGAACACCGAGGCCGAGGCGATCAAGCTGTTTGCGAACACCTATCTTGCGA
TGCGCGTCGCCTTTTTCAACGAGCTGGACACTTATGCCGCCTTGCACGGCGTCGATTCGCGGCAGGTGATCGAGGGGGTG
TGCCTCGATCCCCGGATCGGCAGTTTCTACAACAATCCTTCCTTCGGTTATGGCGGTTATTGCCTGCCCAAGGACACGAA
GCAGATGCTCGCCAATTACAAGGATGTGCCACAGAACCTCATCCAGGCGATCGTCTCCTCGAACACCACGCGCAAGGATT
TCGTCGCGTCGGAGGTCATCAAACGGAACCCGCGCGTCGTCGGCATCCATCGCCTCGCGATGAAGGCGGGGTCGGACAAT
TTCCGCGCCAGCAGCATCCTCGGCGTGATGAAGCGCGTGAAGGCCAAGGGGATCGAGGTGATCGTCTATGAACCGCTTGT
CGCGGAGGACCGGCTGTTCAACTCGCGCGTGATCCGCGATCTCGATGCGTTCAAGGCCGAAGCCGACGTGATTATCGCGA
ACCGTATCACCGACGACCTCGCCGATGTCGTCGACAAGGTTTACAGCCGCGACCTGTTCGGCGCCGACAGCTGA

Upstream 100 bases:

>100_bases
CCGATGCGGCGCCCTATACGACCTTTTGCGGCACATGAAGCATTGAGCCGCCGCCGGGCCGTTGCTACGGACGGCGCCGC
ATCGGCCAAAGGATAAATCA

Downstream 100 bases:

>100_bases
TCTGTCCCGCCCGCCGTCGCCCGCCGTATGACGGGGAACTGTCCCAACGCCGGAGCGTTGGCACCCGGCGAAGGGGAGAA
ACGGGTTGCACAGCCAAAGC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTSAKDSPVKIAVVGTGYVGISNAVLLAQHNAVVALDIDTRKVELVNARQSPIVDPEIEDYLANKQLNLVATTDKQAAYA
DANFVIVATPTDYDPDTNYFNTNSVESVIADALKLAPGALVVVKSTVPVGFTERMRAEHGSNDIVFSPEFLREGRALHDN
LHPSRIIVGNTHPRAADFARLLLEGSLKPDTAVLQTGNTEAEAIKLFANTYLAMRVAFFNELDTYAALHGVDSRQVIEGV
CLDPRIGSFYNNPSFGYGGYCLPKDTKQMLANYKDVPQNLIQAIVSSNTTRKDFVASEVIKRNPRVVGIHRLAMKAGSDN
FRASSILGVMKRVKAKGIEVIVYEPLVAEDRLFNSRVIRDLDAFKAEADVIIANRITDDLADVVDKVYSRDLFGADS

Sequences:

>Translated_397_residues
MTSAKDSPVKIAVVGTGYVGISNAVLLAQHNAVVALDIDTRKVELVNARQSPIVDPEIEDYLANKQLNLVATTDKQAAYA
DANFVIVATPTDYDPDTNYFNTNSVESVIADALKLAPGALVVVKSTVPVGFTERMRAEHGSNDIVFSPEFLREGRALHDN
LHPSRIIVGNTHPRAADFARLLLEGSLKPDTAVLQTGNTEAEAIKLFANTYLAMRVAFFNELDTYAALHGVDSRQVIEGV
CLDPRIGSFYNNPSFGYGGYCLPKDTKQMLANYKDVPQNLIQAIVSSNTTRKDFVASEVIKRNPRVVGIHRLAMKAGSDN
FRASSILGVMKRVKAKGIEVIVYEPLVAEDRLFNSRVIRDLDAFKAEADVIIANRITDDLADVVDKVYSRDLFGADS
>Mature_396_residues
TSAKDSPVKIAVVGTGYVGISNAVLLAQHNAVVALDIDTRKVELVNARQSPIVDPEIEDYLANKQLNLVATTDKQAAYAD
ANFVIVATPTDYDPDTNYFNTNSVESVIADALKLAPGALVVVKSTVPVGFTERMRAEHGSNDIVFSPEFLREGRALHDNL
HPSRIIVGNTHPRAADFARLLLEGSLKPDTAVLQTGNTEAEAIKLFANTYLAMRVAFFNELDTYAALHGVDSRQVIEGVC
LDPRIGSFYNNPSFGYGGYCLPKDTKQMLANYKDVPQNLIQAIVSSNTTRKDFVASEVIKRNPRVVGIHRLAMKAGSDNF
RASSILGVMKRVKAKGIEVIVYEPLVAEDRLFNSRVIRDLDAFKAEADVIIANRITDDLADVVDKVYSRDLFGADS

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=377, Percent_Identity=25.7294429708223, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI296040438, Length=253, Percent_Identity=26.8774703557312, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI296040443, Length=360, Percent_Identity=23.3333333333333, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=64.4329896907217, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI48994968, Length=401, Percent_Identity=26.4339152119701, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17560350, Length=382, Percent_Identity=28.7958115183246, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136908, Length=383, Percent_Identity=26.1096605744125, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43389; Mature: 43258

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAKDSPVKIAVVGTGYVGISNAVLLAQHNAVVALDIDTRKVELVNARQSPIVDPEIED
CCCCCCCCEEEEEEECCCCCCCCEEEEEECCEEEEEECCCCEEEEECCCCCCCCCCCHHH
YLANKQLNLVATTDKQAAYADANFVIVATPTDYDPDTNYFNTNSVESVIADALKLAPGAL
HHCCCCEEEEEECCCCCEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
VVVKSTVPVGFTERMRAEHGSNDIVFSPEFLREGRALHDNLHPSRIIVGNTHPRAADFAR
EEEECCCCCCHHHHHHHHCCCCCEEECHHHHHCCCHHHCCCCCCEEEEECCCCCHHHHHH
LLLEGSLKPDTAVLQTGNTEAEAIKLFANTYLAMRVAFFNELDTYAALHGVDSRQVIEGV
HHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCE
CLDPRIGSFYNNPSFGYGGYCLPKDTKQMLANYKDVPQNLIQAIVSSNTTRKDFVASEVI
ECCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KRNPRVVGIHRLAMKAGSDNFRASSILGVMKRVKAKGIEVIVYEPLVAEDRLFNSRVIRD
HCCCCEEEEEHEEHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHH
LDAFKAEADVIIANRITDDLADVVDKVYSRDLFGADS
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSAKDSPVKIAVVGTGYVGISNAVLLAQHNAVVALDIDTRKVELVNARQSPIVDPEIED
CCCCCCCEEEEEEECCCCCCCCEEEEEECCEEEEEECCCCEEEEECCCCCCCCCCCHHH
YLANKQLNLVATTDKQAAYADANFVIVATPTDYDPDTNYFNTNSVESVIADALKLAPGAL
HHCCCCEEEEEECCCCCEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
VVVKSTVPVGFTERMRAEHGSNDIVFSPEFLREGRALHDNLHPSRIIVGNTHPRAADFAR
EEEECCCCCCHHHHHHHHCCCCCEEECHHHHHCCCHHHCCCCCCEEEEECCCCCHHHHHH
LLLEGSLKPDTAVLQTGNTEAEAIKLFANTYLAMRVAFFNELDTYAALHGVDSRQVIEGV
HHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCE
CLDPRIGSFYNNPSFGYGGYCLPKDTKQMLANYKDVPQNLIQAIVSSNTTRKDFVASEVI
ECCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KRNPRVVGIHRLAMKAGSDNFRASSILGVMKRVKAKGIEVIVYEPLVAEDRLFNSRVIRD
HCCCCEEEEEHEEHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHH
LDAFKAEADVIIANRITDDLADVVDKVYSRDLFGADS
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7682279 [H]