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The map label for this gene is cfa [H]

Identifier: 103487030

GI number: 103487030

Start: 1611507

End: 1612787

Strand: Reverse

Name: cfa [H]

Synonym: Sala_1545

Alternate gene names: 103487030

Gene position: 1612787-1611507 (Counterclockwise)

Preceding gene: 103487031

Following gene: 103487029

Centisome position: 48.21

GC content: 66.67

Gene sequence:

>1281_bases
ATGAACACGCATGTCAGCCCCCGCCGCGGCAAGGAACTGCTCCGCGCCGACCGTGCCTATCGCGCGGGCGGGGTGATGGC
GCGGTTGATTGCGCTGGCGCCGACGGCGCTGTTCCACCGCCTGCTCGACCGCATCGACGCGGGGCTGCTCGCCGGGACGA
TCGAGGGGCATTTGCCCGACGGGAGCGTCCGGCTGCTCGGCGGGCGCGGCAGGGGGCCGACGGCGATCGTCCATCTGCAC
AGCTGGGCGGCGCTGGCGCGGCTTGCGCTGTCGGGGTCGGTCGGCTGGTACCGCGCGTGGGAAAAGGGCGAATGGACGTC
GCCCGATCCGGTGCCGCTGTTCGACCTGTTCATGCGCAATGGCGAGGCGCTGGGTAATGCAGGGCGCGCGCACGGCCCGT
CGCGCTGGCTGAACCGCGTTATTCACGCGCTTCACCGCAACGACCGGCGCGGGGCGCGGCGCAACATCCACGCGCATTAT
GATTTGGGCAATGATTTCTATCGGTTATGGCTCGATCATGCGATGAACTATTCGAGCGCACTATTCGCCGATCCGGCCCA
GTCGCTGGAGGAAGCGCAGGCGGCAAAGCTCGACGCGATCCTCGACCGGCTCGACCTCAGGTCGGGAAGCCGGCTGCTCG
AAATCGGCTGCGGTTGGGGCGCACTCGCCGAACGCGCGGTCGAGCGGCACGATGTGATCTATACCGGCATCACCCTGTCG
CCCTCGCAAGCCGAAATCGCCGACGCGCGGCTGGCGGCGGTCGATCTGTCGGGGCGTTCGCGGATCGAGCTTTGCGACTA
TCGCGACGTACAGGGGCCGTACGACGCGATCGCCAGCGTCGAAATGGTCGAAGCGGTGGGGCAGGCCTATTGGCCCGCCT
ATCTCGATGCGATCGCGCGCTTGTTGCGGCCCGGCGGCAAGGCGGCGATCCAGTATATCCTGATCAACGACGCGCTGTTC
GAGCGCTATGCGGCGAGCAGCGATTTCATTCAGGCCTATATCTTCCCCGGCGGCTGCCTGCTGTCCGAAAGTCGCTTCCG
CGCGCTCGCGGAGGAACGAGGGCTGATCTGGCGCGACGCTCATCATTTTGGCGGCGACTATGCAGAAACGCTGCGCCAAT
GGCGCGAGCGTTTCGACGCCGCGGTGGCCGACGATCGGCTGCCGCCCGGTTTCGACGCACGGTTCGTCGGGCTTTGGCGC
TATTATCTGCAATATTGCGAGGGAGGCTTTCGCGGCGGCGGGATCGACGTCGCGCAGGTCACACTTGAAAAACCGGCTTG
A

Upstream 100 bases:

>100_bases
TACCGCCAGCGAACCCCTATAGATCGCCCGCGCGTGTGACGTCATGGCCGCATCGTTTCAGACGATTGTCAGCCGTCCGC
CTTTGAGGCAGGAAGGGGCT

Downstream 100 bases:

>100_bases
GAACAGGGGAGGAAACAAGATGCGACGATTCCTGGCGGCGGTGCTGTTCGGCGCCGCGGCGGCGTGCAGTGTGCCCGCGA
CGACGCAAACCACCGATCAA

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MNTHVSPRRGKELLRADRAYRAGGVMARLIALAPTALFHRLLDRIDAGLLAGTIEGHLPDGSVRLLGGRGRGPTAIVHLH
SWAALARLALSGSVGWYRAWEKGEWTSPDPVPLFDLFMRNGEALGNAGRAHGPSRWLNRVIHALHRNDRRGARRNIHAHY
DLGNDFYRLWLDHAMNYSSALFADPAQSLEEAQAAKLDAILDRLDLRSGSRLLEIGCGWGALAERAVERHDVIYTGITLS
PSQAEIADARLAAVDLSGRSRIELCDYRDVQGPYDAIASVEMVEAVGQAYWPAYLDAIARLLRPGGKAAIQYILINDALF
ERYAASSDFIQAYIFPGGCLLSESRFRALAEERGLIWRDAHHFGGDYAETLRQWRERFDAAVADDRLPPGFDARFVGLWR
YYLQYCEGGFRGGGIDVAQVTLEKPA

Sequences:

>Translated_426_residues
MNTHVSPRRGKELLRADRAYRAGGVMARLIALAPTALFHRLLDRIDAGLLAGTIEGHLPDGSVRLLGGRGRGPTAIVHLH
SWAALARLALSGSVGWYRAWEKGEWTSPDPVPLFDLFMRNGEALGNAGRAHGPSRWLNRVIHALHRNDRRGARRNIHAHY
DLGNDFYRLWLDHAMNYSSALFADPAQSLEEAQAAKLDAILDRLDLRSGSRLLEIGCGWGALAERAVERHDVIYTGITLS
PSQAEIADARLAAVDLSGRSRIELCDYRDVQGPYDAIASVEMVEAVGQAYWPAYLDAIARLLRPGGKAAIQYILINDALF
ERYAASSDFIQAYIFPGGCLLSESRFRALAEERGLIWRDAHHFGGDYAETLRQWRERFDAAVADDRLPPGFDARFVGLWR
YYLQYCEGGFRGGGIDVAQVTLEKPA
>Mature_426_residues
MNTHVSPRRGKELLRADRAYRAGGVMARLIALAPTALFHRLLDRIDAGLLAGTIEGHLPDGSVRLLGGRGRGPTAIVHLH
SWAALARLALSGSVGWYRAWEKGEWTSPDPVPLFDLFMRNGEALGNAGRAHGPSRWLNRVIHALHRNDRRGARRNIHAHY
DLGNDFYRLWLDHAMNYSSALFADPAQSLEEAQAAKLDAILDRLDLRSGSRLLEIGCGWGALAERAVERHDVIYTGITLS
PSQAEIADARLAAVDLSGRSRIELCDYRDVQGPYDAIASVEMVEAVGQAYWPAYLDAIARLLRPGGKAAIQYILINDALF
ERYAASSDFIQAYIFPGGCLLSESRFRALAEERGLIWRDAHHFGGDYAETLRQWRERFDAAVADDRLPPGFDARFVGLWR
YYLQYCEGGFRGGGIDVAQVTLEKPA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=267, Percent_Identity=38.9513108614232, Blast_Score=169, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI133904226, Length=376, Percent_Identity=35.3723404255319, Blast_Score=210, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47299; Mature: 47299

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHVSPRRGKELLRADRAYRAGGVMARLIALAPTALFHRLLDRIDAGLLAGTIEGHLPD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
GSVRLLGGRGRGPTAIVHLHSWAALARLALSGSVGWYRAWEKGEWTSPDPVPLFDLFMRN
CCEEEEECCCCCCEEEEEEHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCHHHHHHHHC
GEALGNAGRAHGPSRWLNRVIHALHRNDRRGARRNIHAHYDLGNDFYRLWLDHAMNYSSA
CHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEECCCHHHHHHHHHHHCCCCHH
LFADPAQSLEEAQAAKLDAILDRLDLRSGSRLLEIGCGWGALAERAVERHDVIYTGITLS
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCEEEEEEEEC
PSQAEIADARLAAVDLSGRSRIELCDYRDVQGPYDAIASVEMVEAVGQAYWPAYLDAIAR
CCHHHHHHHHEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRPGGKAAIQYILINDALFERYAASSDFIQAYIFPGGCLLSESRFRALAEERGLIWRDA
HHCCCCHHEEEEEEECHHHHHHHCCCCCCEEEEEECCCCEECHHHHHHHHHHCCCEEECH
HHFGGDYAETLRQWRERFDAAVADDRLPPGFDARFVGLWRYYLQYCEGGFRGGGIDVAQV
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEE
TLEKPA
EECCCC
>Mature Secondary Structure
MNTHVSPRRGKELLRADRAYRAGGVMARLIALAPTALFHRLLDRIDAGLLAGTIEGHLPD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
GSVRLLGGRGRGPTAIVHLHSWAALARLALSGSVGWYRAWEKGEWTSPDPVPLFDLFMRN
CCEEEEECCCCCCEEEEEEHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCHHHHHHHHC
GEALGNAGRAHGPSRWLNRVIHALHRNDRRGARRNIHAHYDLGNDFYRLWLDHAMNYSSA
CHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEECCCHHHHHHHHHHHCCCCHH
LFADPAQSLEEAQAAKLDAILDRLDLRSGSRLLEIGCGWGALAERAVERHDVIYTGITLS
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCEEEEEEEEC
PSQAEIADARLAAVDLSGRSRIELCDYRDVQGPYDAIASVEMVEAVGQAYWPAYLDAIAR
CCHHHHHHHHEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRPGGKAAIQYILINDALFERYAASSDFIQAYIFPGGCLLSESRFRALAEERGLIWRDA
HHCCCCHHEEEEEEECHHHHHHHCCCCCCEEEEEECCCCEECHHHHHHHHHHCCCEEECH
HHFGGDYAETLRQWRERFDAAVADDRLPPGFDARFVGLWRYYLQYCEGGFRGGGIDVAQV
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEE
TLEKPA
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]