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The map label for this gene is dctB [H]

Identifier: 103486942

GI number: 103486942

Start: 1510112

End: 1511968

Strand: Direct

Name: dctB [H]

Synonym: Sala_1457

Alternate gene names: 103486942

Gene position: 1510112-1511968 (Clockwise)

Preceding gene: 103486936

Following gene: 103486943

Centisome position: 45.14

GC content: 69.09

Gene sequence:

>1857_bases
GTGCGAAACACCGCATACCAAATCATCAAAGTGTGCAACAATCCGCACATGATCGATTCGCGCGATTCGTCCGTCATCGC
TCCCGTGACCGGTCGCCGCCGGTTGCTGATCGCGGTCGCGGCGGGGCTGGCGATCCTGTTGCTCGCCGGATTTGGTCTTG
CCCATTGGGCCGCCGGGCGCGCCGGGGCGCAAACGGCCGTCGAGGCGCAACAGAATGCCCGCGCGCACGCGAGCCTGCTC
GAAAGCGAGTTGCAGAAGTTCCGCCTCCTGCCCCGCGTGCTTACCGAATTTCCCGATGTGCGCGCGGCGCTCGCGGACAA
GAGCGATGCGGCATCGCGTCGCCTTGACCGCGAGCTCGAACAGCTTGCGACGCGCACCGATGCCGCGGTGATTTACGTTC
TCGATGCCGATGGCACGACCATCGCGGCGAGCAACTGGCAGTCGCCGACCAGCTTCGTCGGCGAGAATTATCGTTTCCGT
CCCTATTTTCGGGACGCGATGCAGCGCGGCGACGCCGAACTGTTCGCGCTGGGGACGGTGAGCGGACGCCCCGGCCTTTA
CCTCGCACGGCGCGTCAACGCGGGCGGCGACGCGGACGGGCGGGCGCTCGGCGTGATCGTGCTCAAGGTCGAGTTCGACA
AGCTCGAAACGCGCTGGGCCGACTCCGCCGCGACCACGCTCGTCACCGACGCGGCGGGCATCGTCGTGATGAGCAGCGCG
CCGCGCTGGCGCTTCCGGTCTTTCGGTGCCTTGTCGGCGCGTGATCGTCAGCGGCTGCGCGCGACGCGCAGCTATGGCGA
CGCGCCGCTGGATCCGTTGCCGCTGCGCCGCACGGGAGACGTTCTCCGCATCGGCGACCAGTCCTATTTTCAGGTGGCGG
AGCGGGTGTCGCTGCCCGGCAGCACGCTTCGCCTGCTCCAGCCCGCCGAACCCGCACGCGCGAGCGCCAATGCGACCGCG
CGCGTGATATTCCTCATCCTCCTCATCCTGGTCGGCGCGGCGATCGTCAGCTTGCTCCGCCTCGTCGAGCGGCAGGCGCT
GCGACAGGCGGCGCATGAGGCGCTCGAACGCGAGGTTGCCGCGCGCACGCGCGATCTGCGCGCCGCGAACGACGAATTGC
GGCAGGCATCCGAGCGGCAGGCCGAAACCGACCGTCGCTATCGCGCCGCGCGCGAGGAGCTGGCGCAGGCCAGCCGCCTC
GGCTCGATCGGGCAGATCACCGCCGGGGTCGCGCACGAGATCAACCAGCCGGTCGCAGCGATCCGCAGCTTTGCCGAAAA
TGCCCTCGCCTATCTGGGTCGGTCAGAGGGCGACAAGGCGCGCGCCAATCTGGACCATATCGTCGCGCTGACCGCGCGCG
TCGGCGCGATCACCGGCGAGTTGCGCAATTTTGCGCGCCGCGCGACCGCGCCGCTGGGGCCGGTGGCGTTGCAGTCAGCG
ATCGACGGCACGCTGCTGCTGATCGGCGACCGGCTGCGCGCGCAGGGCATCGCGCTCGATGTCGAGTTGGCGAACCCGGC
CGCGACCGTCCACGCCGACCGCGTCCGGCTGGAGCAAATCCTGGTCAACCTCCTGCAAAATGCCGCCGATGCAGTGCGCG
GCCTCGAAGGCGCCCGCATCAGCCTGACCGCGCACGGCGGCGATCCGGTGGCGATCGATATTTGCGACAATGGGCCGGGC
GTGCCCGCCGACCTGAAGCCACAATTGTTCACGCCCTTCGTCACCGGGCGCCCCGATGGGCTGGGGCTGGGACTCGCGAT
CGCGAGCGACATCGCCAAAGCGTTCGGCGGTACGCTCTCGATCATCCCCTCACCGCTCGGTGGTGCGGGGTTCCGCGTGA
CGCTGAGGCCGGCATGA

Upstream 100 bases:

>100_bases
GGAGTTGGCGGATCGGGGGTCAAACGGGCGATGGAATCTATCTACGATTTTGTATTTCTTACTTTAATTATTTTGCCGCG
TCGACGCGGAGAGACAAATT

Downstream 100 bases:

>100_bases
GTTTCTTCACCGCCGAGCAGACGATCCTTTTCGTCGACGACGATGCCGCACTGCGCGAAGCGAATGCGCAGACGCTCGAC
CTTGCGGGCCTTGCGGTCGA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MRNTAYQIIKVCNNPHMIDSRDSSVIAPVTGRRRLLIAVAAGLAILLLAGFGLAHWAAGRAGAQTAVEAQQNARAHASLL
ESELQKFRLLPRVLTEFPDVRAALADKSDAASRRLDRELEQLATRTDAAVIYVLDADGTTIAASNWQSPTSFVGENYRFR
PYFRDAMQRGDAELFALGTVSGRPGLYLARRVNAGGDADGRALGVIVLKVEFDKLETRWADSAATTLVTDAAGIVVMSSA
PRWRFRSFGALSARDRQRLRATRSYGDAPLDPLPLRRTGDVLRIGDQSYFQVAERVSLPGSTLRLLQPAEPARASANATA
RVIFLILLILVGAAIVSLLRLVERQALRQAAHEALEREVAARTRDLRAANDELRQASERQAETDRRYRAAREELAQASRL
GSIGQITAGVAHEINQPVAAIRSFAENALAYLGRSEGDKARANLDHIVALTARVGAITGELRNFARRATAPLGPVALQSA
IDGTLLLIGDRLRAQGIALDVELANPAATVHADRVRLEQILVNLLQNAADAVRGLEGARISLTAHGGDPVAIDICDNGPG
VPADLKPQLFTPFVTGRPDGLGLGLAIASDIAKAFGGTLSIIPSPLGGAGFRVTLRPA

Sequences:

>Translated_618_residues
MRNTAYQIIKVCNNPHMIDSRDSSVIAPVTGRRRLLIAVAAGLAILLLAGFGLAHWAAGRAGAQTAVEAQQNARAHASLL
ESELQKFRLLPRVLTEFPDVRAALADKSDAASRRLDRELEQLATRTDAAVIYVLDADGTTIAASNWQSPTSFVGENYRFR
PYFRDAMQRGDAELFALGTVSGRPGLYLARRVNAGGDADGRALGVIVLKVEFDKLETRWADSAATTLVTDAAGIVVMSSA
PRWRFRSFGALSARDRQRLRATRSYGDAPLDPLPLRRTGDVLRIGDQSYFQVAERVSLPGSTLRLLQPAEPARASANATA
RVIFLILLILVGAAIVSLLRLVERQALRQAAHEALEREVAARTRDLRAANDELRQASERQAETDRRYRAAREELAQASRL
GSIGQITAGVAHEINQPVAAIRSFAENALAYLGRSEGDKARANLDHIVALTARVGAITGELRNFARRATAPLGPVALQSA
IDGTLLLIGDRLRAQGIALDVELANPAATVHADRVRLEQILVNLLQNAADAVRGLEGARISLTAHGGDPVAIDICDNGPG
VPADLKPQLFTPFVTGRPDGLGLGLAIASDIAKAFGGTLSIIPSPLGGAGFRVTLRPA
>Mature_618_residues
MRNTAYQIIKVCNNPHMIDSRDSSVIAPVTGRRRLLIAVAAGLAILLLAGFGLAHWAAGRAGAQTAVEAQQNARAHASLL
ESELQKFRLLPRVLTEFPDVRAALADKSDAASRRLDRELEQLATRTDAAVIYVLDADGTTIAASNWQSPTSFVGENYRFR
PYFRDAMQRGDAELFALGTVSGRPGLYLARRVNAGGDADGRALGVIVLKVEFDKLETRWADSAATTLVTDAAGIVVMSSA
PRWRFRSFGALSARDRQRLRATRSYGDAPLDPLPLRRTGDVLRIGDQSYFQVAERVSLPGSTLRLLQPAEPARASANATA
RVIFLILLILVGAAIVSLLRLVERQALRQAAHEALEREVAARTRDLRAANDELRQASERQAETDRRYRAAREELAQASRL
GSIGQITAGVAHEINQPVAAIRSFAENALAYLGRSEGDKARANLDHIVALTARVGAITGELRNFARRATAPLGPVALQSA
IDGTLLLIGDRLRAQGIALDVELANPAATVHADRVRLEQILVNLLQNAADAVRGLEGARISLTAHGGDPVAIDICDNGPG
VPADLKPQLFTPFVTGRPDGLGLGLAIASDIAKAFGGTLSIIPSPLGGAGFRVTLRPA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=31.9327731092437, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=31.2236286919831, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=314, Percent_Identity=28.0254777070064, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=28.8537549407115, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1789149, Length=280, Percent_Identity=25, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=279, Percent_Identity=30.1075268817204, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66161; Mature: 66161

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNTAYQIIKVCNNPHMIDSRDSSVIAPVTGRRRLLIAVAAGLAILLLAGFGLAHWAAGR
CCCHHHHHHHHHCCCCEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCC
AGAQTAVEAQQNARAHASLLESELQKFRLLPRVLTEFPDVRAALADKSDAASRRLDRELE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHH
QLATRTDAAVIYVLDADGTTIAASNWQSPTSFVGENYRFRPYFRDAMQRGDAELFALGTV
HHHHCCCCEEEEEECCCCCEEEECCCCCCHHHHCCCCEECHHHHHHHHCCCCEEEEEEEC
SGRPGLYLARRVNAGGDADGRALGVIVLKVEFDKLETRWADSAATTLVTDAAGIVVMSSA
CCCCCEEEEEEECCCCCCCCCEEEEEEEEEEHHHHHHHHCCHHHHHHHCCCCCEEEEECC
PRWRFRSFGALSARDRQRLRATRSYGDAPLDPLPLRRTGDVLRIGDQSYFQVAERVSLPG
CCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCC
STLRLLQPAEPARASANATARVIFLILLILVGAAIVSLLRLVERQALRQAAHEALEREVA
CHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARTRDLRAANDELRQASERQAETDRRYRAAREELAQASRLGSIGQITAGVAHEINQPVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHH
IRSFAENALAYLGRSEGDKARANLDHIVALTARVGAITGELRNFARRATAPLGPVALQSA
HHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IDGTLLLIGDRLRAQGIALDVELANPAATVHADRVRLEQILVNLLQNAADAVRGLEGARI
CCCEEEEEECCHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SLTAHGGDPVAIDICDNGPGVPADLKPQLFTPFVTGRPDGLGLGLAIASDIAKAFGGTLS
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCEEE
IIPSPLGGAGFRVTLRPA
ECCCCCCCCCEEEEEECC
>Mature Secondary Structure
MRNTAYQIIKVCNNPHMIDSRDSSVIAPVTGRRRLLIAVAAGLAILLLAGFGLAHWAAGR
CCCHHHHHHHHHCCCCEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCC
AGAQTAVEAQQNARAHASLLESELQKFRLLPRVLTEFPDVRAALADKSDAASRRLDRELE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHH
QLATRTDAAVIYVLDADGTTIAASNWQSPTSFVGENYRFRPYFRDAMQRGDAELFALGTV
HHHHCCCCEEEEEECCCCCEEEECCCCCCHHHHCCCCEECHHHHHHHHCCCCEEEEEEEC
SGRPGLYLARRVNAGGDADGRALGVIVLKVEFDKLETRWADSAATTLVTDAAGIVVMSSA
CCCCCEEEEEEECCCCCCCCCEEEEEEEEEEHHHHHHHHCCHHHHHHHCCCCCEEEEECC
PRWRFRSFGALSARDRQRLRATRSYGDAPLDPLPLRRTGDVLRIGDQSYFQVAERVSLPG
CCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCC
STLRLLQPAEPARASANATARVIFLILLILVGAAIVSLLRLVERQALRQAAHEALEREVA
CHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARTRDLRAANDELRQASERQAETDRRYRAAREELAQASRLGSIGQITAGVAHEINQPVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHH
IRSFAENALAYLGRSEGDKARANLDHIVALTARVGAITGELRNFARRATAPLGPVALQSA
HHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IDGTLLLIGDRLRAQGIALDVELANPAATVHADRVRLEQILVNLLQNAADAVRGLEGARI
CCCEEEEEECCHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SLTAHGGDPVAIDICDNGPGVPADLKPQLFTPFVTGRPDGLGLGLAIASDIAKAFGGTLS
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCEEE
IIPSPLGGAGFRVTLRPA
ECCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]