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The map label for this gene is mip [H]

Identifier: 103486898

GI number: 103486898

Start: 1465186

End: 1465833

Strand: Reverse

Name: mip [H]

Synonym: Sala_1412

Alternate gene names: 103486898

Gene position: 1465833-1465186 (Counterclockwise)

Preceding gene: 103486902

Following gene: 103486891

Centisome position: 43.82

GC content: 65.9

Gene sequence:

>648_bases
ATGGCGGCGCGCCCCGGCGCATTTGCCTCTGGACCGTGTGATGCCGCTCCGCCTATAGGCCTCACCGACAGTTTTGCGCC
AACGGCGCTTGCGGAAGGATCAGCGGAAATGAGCGTGACGACGGTTCCATTGCGCCCGGTGAACAAGGGCGGGCTGTGGC
TGATGTGGCTGGGCGTGATCGCGCTGATCGTCGCCGCCGCGGCTTTCGCCTGGCACATGACCCCGCGCATCGGCTTCGAG
GTCGTCAAGGAAGGCAGCGGCCCCAGCCCGACCAAGGCCGATGTCGTGCTGGTGAAATATGAAGGCAAGCTCGCCGACGG
CACTGTTTTCGACGCCAATGAACAGGCGCCGATGCAGGTCGCGCAGGTCGTGCCGGGCTTTTCCGAGGCACTCACGCGGA
TGCGCAAGGGTGGCGAATACAGGATCACCATCCCGCCGCAGCTTGGCTATGGCGACCGCGCGGTCGGGCCAATCCCCGCG
AACAGCACGCTGCATTTCACCGTCACCCTGCTCGATTTCCGCTCGGAGGCCGAGGTTCGCGCGATGCAGCAGCAGATGCA
GCAGATGCAACAGATGCAGCAGCAACAGATGATGCAGGGCGGTCCCGGTGGGCCGGCCGGTCCGCCGCCGGGTGCGCCGC
AGCCTTAA

Upstream 100 bases:

>100_bases
GTGCAAGCGTCGCGGCCGCGAGCAATCCGAATCTGCGCATGGAATCTCCCCTGAGTGATGGCGTCATCGTGACGCGCCGC
CCGGGACGGGGCAAGGGGGA

Downstream 100 bases:

>100_bases
CAGAATCGTCGCCCCCGCGAAGGCGGGGGCCGCTATCGGCATAGCGCAAGGATACCAGCGGCCCCCGCCTCCGCGGGGGC
GATGAGCCCTCAGCTTGCCG

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: Macrophage infectivity potentiator; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MAARPGAFASGPCDAAPPIGLTDSFAPTALAEGSAEMSVTTVPLRPVNKGGLWLMWLGVIALIVAAAAFAWHMTPRIGFE
VVKEGSGPSPTKADVVLVKYEGKLADGTVFDANEQAPMQVAQVVPGFSEALTRMRKGGEYRITIPPQLGYGDRAVGPIPA
NSTLHFTVTLLDFRSEAEVRAMQQQMQQMQQMQQQQMMQGGPGGPAGPPPGAPQP

Sequences:

>Translated_215_residues
MAARPGAFASGPCDAAPPIGLTDSFAPTALAEGSAEMSVTTVPLRPVNKGGLWLMWLGVIALIVAAAAFAWHMTPRIGFE
VVKEGSGPSPTKADVVLVKYEGKLADGTVFDANEQAPMQVAQVVPGFSEALTRMRKGGEYRITIPPQLGYGDRAVGPIPA
NSTLHFTVTLLDFRSEAEVRAMQQQMQQMQQMQQQQMMQGGPGGPAGPPPGAPQP
>Mature_214_residues
AARPGAFASGPCDAAPPIGLTDSFAPTALAEGSAEMSVTTVPLRPVNKGGLWLMWLGVIALIVAAAAFAWHMTPRIGFEV
VKEGSGPSPTKADVVLVKYEGKLADGTVFDANEQAPMQVAQVVPGFSEALTRMRKGGEYRITIPPQLGYGDRAVGPIPAN
STLHFTVTLLDFRSEAEVRAMQQQMQQMQQMQQQQMMQGGPGGPAGPPPGAPQP

Specific function: Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI87082390, Length=100, Percent_Identity=47, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789745, Length=100, Percent_Identity=42, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008104
- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 22639; Mature: 22508

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARPGAFASGPCDAAPPIGLTDSFAPTALAEGSAEMSVTTVPLRPVNKGGLWLMWLGVI
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHH
ALIVAAAAFAWHMTPRIGFEVVKEGSGPSPTKADVVLVKYEGKLADGTVFDANEQAPMQV
HHHHHHHHHHHHCCCHHCHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCHHHH
AQVVPGFSEALTRMRKGGEYRITIPPQLGYGDRAVGPIPANSTLHFTVTLLDFRSEAEVR
HHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHH
AMQQQMQQMQQMQQQQMMQGGPGGPAGPPPGAPQP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AARPGAFASGPCDAAPPIGLTDSFAPTALAEGSAEMSVTTVPLRPVNKGGLWLMWLGVI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHH
ALIVAAAAFAWHMTPRIGFEVVKEGSGPSPTKADVVLVKYEGKLADGTVFDANEQAPMQV
HHHHHHHHHHHHCCCHHCHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCHHHH
AQVVPGFSEALTRMRKGGEYRITIPPQLGYGDRAVGPIPANSTLHFTVTLLDFRSEAEVR
HHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHH
AMQQQMQQMQQMQQQQMMQGGPGGPAGPPPGAPQP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1840577 [H]