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The map label for this gene is ctaC [H]

Identifier: 103486891

GI number: 103486891

Start: 1459884

End: 1460915

Strand: Reverse

Name: ctaC [H]

Synonym: Sala_1405

Alternate gene names: 103486891

Gene position: 1460915-1459884 (Counterclockwise)

Preceding gene: 103486898

Following gene: 103486890

Centisome position: 43.67

GC content: 65.12

Gene sequence:

>1032_bases
ATGAAGAGCTTGAAAACCCCTGTAATCAAGGTGTTAATCGCGGCAGCCTTGTCGCTTGGCGCGGTCGGCGCCGGTCATGC
GCAGACCGCCGCGACGGCTCCGACCGCGGCGAATCCGGCGCCGGTCGCCGCGCCCGTCGAAGCCCCCGTCGCGGTTCCGG
CGGCTGCCGATGCGGCGTCGCCCGCGGGCGACGCGACCTATGTACCGATGAAGCCGACGCCCGGCGTCGGCCAGCCGGTC
GACCGGGGAATCGACTTCCAGCCGCAGGTCAGCCCGATCGGCGAACAGGCCTATTGGTTCAACCATGTGATGCTGCTGCC
GATCATCACGATCATCTCGCTCTTCGTTCTCGGCCTGCTGCTGTGGGTTATCTTTCGCTATCGCGCCAGGGCGAACCCGG
TGCCGTCAAAGACGACACACAATACCTTCATCGAGATCGTCTGGACCGCGATCCCCGTCCTCATCCTCGCGGTGATCGCG
GTGCCGTCGATCCGTCTGCTCGCGGCGCAATATGAACCGCCCAAGAAGGACGCGCTGACGATCAAGGTCACCGGATACCA
ATGGTATTGGGGCTATGCCTATCCCGACCAGGGCATCGGCGAATATGTGTCGAAGATGCTGACCAAGGAACAGGCCGACG
CCGCGGGCGAGCCGCACCAGCTCGCCGTCGACAACCGCATGGTCGTCCCCGTCGGGCGGCAGGTGAAGCTGATCGTCACC
GGCGCCGACGTGATCCACAGCTTCGCCGTCCCCGCTTTCTGGACCAAGATGGACGCGGTTCCCGGCCGCGCCAACGAAAC
GACGTTCACCGCCAACAAGGTCGGCGTTTATTACGGCCAGTGCTCGGAGCTTTGCGGCGTCGATCATGGCTATATGCCGA
TCGCGGTCGAAGTGCTGCCGGTCGACAAGTGGGAGGCATGGGTGCGCTCGAAAGGCGGCAACCCGAATGGCCCGGTCGTC
GAGACCGCCGCCGCCACGACCGTATCCGCGCCAGCTGCGGCTCCCGCCGCCATCCCGGCTGCCAAGAATTAA

Upstream 100 bases:

>100_bases
AGATTCAGCCGGTCCGATGGCTGCGCGGGCGCATGTCCGGCGGCGGGAATGGCGGGCTGGGGAATCATAAATACAACAGG
CAACGGGCGGCACTATCCTT

Downstream 100 bases:

>100_bases
CAAGGGGTCCGACAGATGACCGATATCGCAGCGACTGCACCCGCGCACGGCCATGCCGATCACGCGCACGACCATGATCA
CGACACTCCGGGCTTTTTCG

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKSLKTPVIKVLIAAALSLGAVGAGHAQTAATAPTAANPAPVAAPVEAPVAVPAAADAASPAGDATYVPMKPTPGVGQPV
DRGIDFQPQVSPIGEQAYWFNHVMLLPIITIISLFVLGLLLWVIFRYRARANPVPSKTTHNTFIEIVWTAIPVLILAVIA
VPSIRLLAAQYEPPKKDALTIKVTGYQWYWGYAYPDQGIGEYVSKMLTKEQADAAGEPHQLAVDNRMVVPVGRQVKLIVT
GADVIHSFAVPAFWTKMDAVPGRANETTFTANKVGVYYGQCSELCGVDHGYMPIAVEVLPVDKWEAWVRSKGGNPNGPVV
ETAAATTVSAPAAAPAAIPAAKN

Sequences:

>Translated_343_residues
MKSLKTPVIKVLIAAALSLGAVGAGHAQTAATAPTAANPAPVAAPVEAPVAVPAAADAASPAGDATYVPMKPTPGVGQPV
DRGIDFQPQVSPIGEQAYWFNHVMLLPIITIISLFVLGLLLWVIFRYRARANPVPSKTTHNTFIEIVWTAIPVLILAVIA
VPSIRLLAAQYEPPKKDALTIKVTGYQWYWGYAYPDQGIGEYVSKMLTKEQADAAGEPHQLAVDNRMVVPVGRQVKLIVT
GADVIHSFAVPAFWTKMDAVPGRANETTFTANKVGVYYGQCSELCGVDHGYMPIAVEVLPVDKWEAWVRSKGGNPNGPVV
ETAAATTVSAPAAAPAAIPAAKN
>Mature_343_residues
MKSLKTPVIKVLIAAALSLGAVGAGHAQTAATAPTAANPAPVAAPVEAPVAVPAAADAASPAGDATYVPMKPTPGVGQPV
DRGIDFQPQVSPIGEQAYWFNHVMLLPIITIISLFVLGLLLWVIFRYRARANPVPSKTTHNTFIEIVWTAIPVLILAVIA
VPSIRLLAAQYEPPKKDALTIKVTGYQWYWGYAYPDQGIGEYVSKMLTKEQADAAGEPHQLAVDNRMVVPVGRQVKLIVT
GADVIHSFAVPAFWTKMDAVPGRANETTFTANKVGVYYGQCSELCGVDHGYMPIAVEVLPVDKWEAWVRSKGGNPNGPVV
ETAAATTVSAPAAAPAAIPAAKN

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=162, Percent_Identity=46.9135802469136, Blast_Score=157, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6226540, Length=210, Percent_Identity=39.0476190476191, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 36198; Mature: 36198

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLKTPVIKVLIAAALSLGAVGAGHAQTAATAPTAANPAPVAAPVEAPVAVPAAADAAS
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCC
PAGDATYVPMKPTPGVGQPVDRGIDFQPQVSPIGEQAYWFNHVMLLPIITIISLFVLGLL
CCCCCEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LWVIFRYRARANPVPSKTTHNTFIEIVWTAIPVLILAVIAVPSIRLLAAQYEPPKKDALT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEE
IKVTGYQWYWGYAYPDQGIGEYVSKMLTKEQADAAGEPHQLAVDNRMVVPVGRQVKLIVT
EEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCEEEEEEE
GADVIHSFAVPAFWTKMDAVPGRANETTFTANKVGVYYGQCSELCGVDHGYMPIAVEVLP
CHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCHHHHHCCCCCCCEEEEEEEE
VDKWEAWVRSKGGNPNGPVVETAAATTVSAPAAAPAAIPAAKN
CHHHHHHHHCCCCCCCCCEEECCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSLKTPVIKVLIAAALSLGAVGAGHAQTAATAPTAANPAPVAAPVEAPVAVPAAADAAS
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCC
PAGDATYVPMKPTPGVGQPVDRGIDFQPQVSPIGEQAYWFNHVMLLPIITIISLFVLGLL
CCCCCEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LWVIFRYRARANPVPSKTTHNTFIEIVWTAIPVLILAVIAVPSIRLLAAQYEPPKKDALT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEE
IKVTGYQWYWGYAYPDQGIGEYVSKMLTKEQADAAGEPHQLAVDNRMVVPVGRQVKLIVT
EEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCEEEEEEE
GADVIHSFAVPAFWTKMDAVPGRANETTFTANKVGVYYGQCSELCGVDHGYMPIAVEVLP
CHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCHHHHHCCCCCCCEEEEEEEE
VDKWEAWVRSKGGNPNGPVVETAAATTVSAPAAAPAAIPAAKN
CHHHHHHHHCCCCCCCCCEEECCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2820725; 7651515; 9380672 [H]