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The map label for this gene is ctaD [H]

Identifier: 103486890

GI number: 103486890

Start: 1458198

End: 1459868

Strand: Reverse

Name: ctaD [H]

Synonym: Sala_1404

Alternate gene names: 103486890

Gene position: 1459868-1458198 (Counterclockwise)

Preceding gene: 103486891

Following gene: 103486889

Centisome position: 43.64

GC content: 62.54

Gene sequence:

>1671_bases
ATGACCGATATCGCAGCGACTGCACCCGCGCACGGCCATGCCGATCACGCGCACGACCATGATCACGACACTCCGGGCTT
TTTCGTCCGCTGGTTCATGTCGACGAACCACAAGGACATCGGCACGCTCTACCTGATCTTCGCGATCGTCGCGGGGATCG
TGGGCGGCGTGCTGTCGGGCATGATGCGCCTCGAACTCGCCGAACCGGGCGTGCAATATCTGGGCGGCTGGGCCGAAATG
CTCGGCGGCGCGGGCGACGAGGTTGCGGGCAAGCATTTCTGGAACGTGATGATCACCGCGCACGGGCTGATCATGGTCTT
CTTCATGGTCATGCCCGCGATGATCGGCGGCTTCGGCAACTGGTTCGTGCCGCTGATGATCGGCGCGCCCGACATGGCCT
TCCCGCGCATGAACAATGTCTCCTTCTGGCTGACCTTCGTGGCGTTCGTCATGCTCGTCGGATCGATGTTCGTGCCCGGC
GGCAGCGGCCTTGGCGCCGGCACCGGCTGGACGGTCTATGCGCCGCTGTCGACCAGTGGTTCGGCCGGGCCCGCGGTCGA
CATGGCGATCTTCTCGCTTCACCTTGCGGGCGCGGCGTCGATCCTCGGCGCGATCAACTTCATCACGACCATCTTCAACA
TGCGCGCGCCGGGCATGACGCTGCACAAGATGCCGCTGTTCGTATGGTCGGTGCTCGTCACCGCCTTCCTGCTGCTGCTC
GCGCTTCCGGTGCTTGCCGCGGCGATCACGATGCTGCTCACCGACCGCAATTTCGGCACCACCTTCTATGATGCGGCGGG
CGGCGGCGATCCCGTGCTTTACCAGCATCTCTTCTGGTTCTTCGGCCACCCCGAAGTCTATATCATGATCCTGCCGGGCT
TCGGCATCGTCAGCCAGGTCATCTCGACCTTCAGCCGCAAGCCGGTGTTCGGCTATCTCGGCATGGCCTATGCCATGGTG
GCGATCGGTGTCGTCGGCTTCATCGTGTGGGCGCACCACATGTTCACCGTCGGCATGAGCGTGAACCTGAAGATGTATTT
CACCGCGGCGACGATGGTGATCGCGGTCCCGACCGGCATCAAGATATTCAGTTGGATCGCGACGATGTGGGGCGGGTCGA
TGAGCTTCAAGACCCCGATGGTCTGGTCGCTGGGCTTCATCTTCATGTTCACCGTCGGCGGCGTGACCGGCGTGGTTCTC
GCCAATGGCGGCGTCGATACCGCGCTTCACGACACCTATTATGTCGTCGCGCACTTCCACTATGTGCTTTCGCTCGGCGC
GGTCTTCTCGCTCTTCGCCGGTTTCTATTACTGGTTCCCGAAGATGTCGGGCCGGATGTACAACGAGGCGCTGGGCCAGC
TGCACTTCTGGATCTTCTTCATCGGCGTGAACGTGCTCTTCTTCCCCCAGCACTTCCTGGGTCAGCAGGGAATGCCGCGC
CGTTACCCCGACTATCCCGACGCCTATGCCTTCTGGCACCTCATCTCGTCCTGGGGCTATGTCATCATGGGCGTGGGCGT
GCTGATCTTCTTCGCGAACATTCTCTGGTCGCTGGTCGCGGGGAAGAAGGCGGCGGACAATCCGTGGGGCGAAGGCGCAA
CGACGCTCGAATGGACGCTGTCGAGCCCGCCGCCGTTCCACCAGTTCAACGAACTGCCGCGTATCGCCTGA

Upstream 100 bases:

>100_bases
TGGCCCGGTCGTCGAGACCGCCGCCGCCACGACCGTATCCGCGCCAGCTGCGGCTCCCGCCGCCATCCCGGCTGCCAAGA
ATTAACAAGGGGTCCGACAG

Downstream 100 bases:

>100_bases
CAGGCCGCGCCCTCTGCTGACTTCCGGCAGGGGGCGCAGCCCTGATGGCCGGAGTGATTATGGCGCAAAGCCTGACCCAT
GATGCGATGACGCTCCCCGC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MTDIAATAPAHGHADHAHDHDHDTPGFFVRWFMSTNHKDIGTLYLIFAIVAGIVGGVLSGMMRLELAEPGVQYLGGWAEM
LGGAGDEVAGKHFWNVMITAHGLIMVFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNVSFWLTFVAFVMLVGSMFVPG
GSGLGAGTGWTVYAPLSTSGSAGPAVDMAIFSLHLAGAASILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLL
ALPVLAAAITMLLTDRNFGTTFYDAAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIVSQVISTFSRKPVFGYLGMAYAMV
AIGVVGFIVWAHHMFTVGMSVNLKMYFTAATMVIAVPTGIKIFSWIATMWGGSMSFKTPMVWSLGFIFMFTVGGVTGVVL
ANGGVDTALHDTYYVVAHFHYVLSLGAVFSLFAGFYYWFPKMSGRMYNEALGQLHFWIFFIGVNVLFFPQHFLGQQGMPR
RYPDYPDAYAFWHLISSWGYVIMGVGVLIFFANILWSLVAGKKAADNPWGEGATTLEWTLSSPPPFHQFNELPRIA

Sequences:

>Translated_556_residues
MTDIAATAPAHGHADHAHDHDHDTPGFFVRWFMSTNHKDIGTLYLIFAIVAGIVGGVLSGMMRLELAEPGVQYLGGWAEM
LGGAGDEVAGKHFWNVMITAHGLIMVFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNVSFWLTFVAFVMLVGSMFVPG
GSGLGAGTGWTVYAPLSTSGSAGPAVDMAIFSLHLAGAASILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLL
ALPVLAAAITMLLTDRNFGTTFYDAAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIVSQVISTFSRKPVFGYLGMAYAMV
AIGVVGFIVWAHHMFTVGMSVNLKMYFTAATMVIAVPTGIKIFSWIATMWGGSMSFKTPMVWSLGFIFMFTVGGVTGVVL
ANGGVDTALHDTYYVVAHFHYVLSLGAVFSLFAGFYYWFPKMSGRMYNEALGQLHFWIFFIGVNVLFFPQHFLGQQGMPR
RYPDYPDAYAFWHLISSWGYVIMGVGVLIFFANILWSLVAGKKAADNPWGEGATTLEWTLSSPPPFHQFNELPRIA
>Mature_555_residues
TDIAATAPAHGHADHAHDHDHDTPGFFVRWFMSTNHKDIGTLYLIFAIVAGIVGGVLSGMMRLELAEPGVQYLGGWAEML
GGAGDEVAGKHFWNVMITAHGLIMVFFMVMPAMIGGFGNWFVPLMIGAPDMAFPRMNNVSFWLTFVAFVMLVGSMFVPGG
SGLGAGTGWTVYAPLSTSGSAGPAVDMAIFSLHLAGAASILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLLA
LPVLAAAITMLLTDRNFGTTFYDAAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIVSQVISTFSRKPVFGYLGMAYAMVA
IGVVGFIVWAHHMFTVGMSVNLKMYFTAATMVIAVPTGIKIFSWIATMWGGSMSFKTPMVWSLGFIFMFTVGGVTGVVLA
NGGVDTALHDTYYVVAHFHYVLSLGAVFSLFAGFYYWFPKMSGRMYNEALGQLHFWIFFIGVNVLFFPQHFLGQQGMPRR
YPDYPDAYAFWHLISSWGYVIMGVGVLIFFANILWSLVAGKKAADNPWGEGATTLEWTLSSPPPFHQFNELPRIA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=524, Percent_Identity=58.969465648855, Blast_Score=581, Evalue=1e-166,
Organism=Escherichia coli, GI1786634, Length=532, Percent_Identity=42.4812030075188, Blast_Score=391, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6226519, Length=542, Percent_Identity=54.9815498154982, Blast_Score=591, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6226524, Length=338, Percent_Identity=58.5798816568047, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6226523, Length=263, Percent_Identity=53.9923954372624, Blast_Score=260, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6226522, Length=91, Percent_Identity=41.7582417582418, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60798; Mature: 60667

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIAATAPAHGHADHAHDHDHDTPGFFVRWFMSTNHKDIGTLYLIFAIVAGIVGGVLSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
MMRLELAEPGVQYLGGWAEMLGGAGDEVAGKHFWNVMITAHGLIMVFFMVMPAMIGGFGN
HHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WFVPLMIGAPDMAFPRMNNVSFWLTFVAFVMLVGSMFVPGGSGLGAGTGWTVYAPLSTSG
CEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCC
SAGPAVDMAIFSLHLAGAASILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALPVLAAAITMLLTDRNFGTTFYDAAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIVSQV
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
ISTFSRKPVFGYLGMAYAMVAIGVVGFIVWAHHMFTVGMSVNLKMYFTAATMVIAVPTGI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEECCCH
KIFSWIATMWGGSMSFKTPMVWSLGFIFMFTVGGVTGVVLANGGVDTALHDTYYVVAHFH
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
YVLSLGAVFSLFAGFYYWFPKMSGRMYNEALGQLHFWIFFIGVNVLFFPQHFLGQQGMPR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
RYPDYPDAYAFWHLISSWGYVIMGVGVLIFFANILWSLVAGKKAADNPWGEGATTLEWTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
SSPPPFHQFNELPRIA
CCCCCCHHHHCCCCCC
>Mature Secondary Structure 
TDIAATAPAHGHADHAHDHDHDTPGFFVRWFMSTNHKDIGTLYLIFAIVAGIVGGVLSG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
MMRLELAEPGVQYLGGWAEMLGGAGDEVAGKHFWNVMITAHGLIMVFFMVMPAMIGGFGN
HHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WFVPLMIGAPDMAFPRMNNVSFWLTFVAFVMLVGSMFVPGGSGLGAGTGWTVYAPLSTSG
CEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCC
SAGPAVDMAIFSLHLAGAASILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALPVLAAAITMLLTDRNFGTTFYDAAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIVSQV
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
ISTFSRKPVFGYLGMAYAMVAIGVVGFIVWAHHMFTVGMSVNLKMYFTAATMVIAVPTGI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEECCCH
KIFSWIATMWGGSMSFKTPMVWSLGFIFMFTVGGVTGVVLANGGVDTALHDTYYVVAHFH
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
YVLSLGAVFSLFAGFYYWFPKMSGRMYNEALGQLHFWIFFIGVNVLFFPQHFLGQQGMPR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
RYPDYPDAYAFWHLISSWGYVIMGVGVLIFFANILWSLVAGKKAADNPWGEGATTLEWTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
SSPPPFHQFNELPRIA
CCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]