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The map label for this gene is glmS [H]

Identifier: 103486852

GI number: 103486852

Start: 1422511

End: 1424334

Strand: Reverse

Name: glmS [H]

Synonym: Sala_1366

Alternate gene names: 103486852

Gene position: 1424334-1422511 (Counterclockwise)

Preceding gene: 103486853

Following gene: 103486851

Centisome position: 42.58

GC content: 66.39

Gene sequence:

>1824_bases
ATGTGCGGAATTATCGGAATCATCGGCAAGGATCAGGTCGCCGAGCGCCTCGTCGACGGCCTCAGGCGCATGGAATATCG
CGGCTATGACAGCGCGGGCGTCTGCACGGTCGAGGGCGGGCAGTTGATCCGCCGCCGCGCCGAGGGCAAGCTGGCCAATC
TGGTGAAGGAACTCGCGGGCAACCCCGCGCCCGGCACCGTGGGTATTGCGCACACGCGCTGGGCGACGCACGGCGCGCCG
ACCACCAGCAACGCGCATCCGCACGCGACCGCCGAAGTCGCGCTCGTTCACAACGGCATCATCGAAAACTTCAAACCGCT
GCGCGAGGGCTTGCAGGCGCGGGGCCGCACGTTCGAAAGCGAGACCGACACGGAGGTCGTCGCGCACCTCGTCAGCGAAC
AGGTCGAGGCGGGCAAGTCGCCGACCGAGGCGGTGCAGGCGATATTGCCAGCGTTGCGCGGCGCCTTTGCGCTCGCCATC
GCCTTTCGCCAGCATCCGGACCTGCTGATCGGCGCGCGCCTTGGCTCGCCCCTCGTCGTCGGCTATGGCGAGGGGGAGAC
TTTCCTCGGTTCCGACGCGCTCGCGCTCGCGCCGCTGACGCAGAGAATCGCCTATCTCGACGAGGGCGACTGGGTCGTCA
TCACGCGCGACGGCGCGCAGATATTCGACAGCGAAAACAATCCGGTCGAACGCGAAGTGACCACGTCGGGTGTCACCGCC
GCGGCGGTCGAGAAGGGCAATTACCGTCATTTCATGCAGAAGGAGATCTTCGAGCAGCCGACCGTCGTGGCGCAGACGCT
CTCCTCCTACATCCGCCCGCTCGAACAGACGGTTGCATTGCCGCAGATGGATTTCGACCTCTCCGCAATCGACCGCATCA
CCATCGTCGCGTGCGGCACCAGCTTCTACGCCGGCATGGTCGCGAAATACTGGTTCGAGACTTTCGCGCGCGTCCCCGTC
GACATCGATGTCGCGTCGGAGTTCCGCTACCGCGACCCGGTGCTGCAACCCGGCGGGCTCGCGCTCTTCATCTCGCAGTC
GGGCGAGACAGCCGACACGCTCGCGGCGCTGCGCCATTGCAAAGCGAATGGGCAGACGATCGCGGTCGTCGTCAACGTCC
CGACGAGCAGCATGGCGCGCGAGGCCGACCTGCTGCTCCCGACCCATGCCGGACCCGAAATCGGCGTCGCCTCGACCAAG
GCCTTCACCTGCCAGCTGGCGGTGCTGGCGGCGCTCGCCGCGCACCTGGCGCTCAAAAAGGGCAAGCTCAGCGCCGCCGA
GGAGCGCGAGATCGTCAAGCATCTGGTCGAAGCGCCCGCTGCGCTCAACGCCGCGCTCGCGCATGACGAGGACATCGCCG
CGATGGCGCACCTGATCGCCCCGGCGCGCGACGTGCTTTATCTCGGCCGCGGTCCCGACTATCCGCTCGCGCTCGAAGGC
GCGCTGAAGCTCAAGGAAATCAGCTATATCCACGCCGAAGGCTATGCGTCGGGTGAAATGAAGCATGGGCCCATCGCGCT
GATCGACGAGGCGGTCCCGGTGATCGTTCTCGCGCCCAGCGGCCCGCTCTTTGAAAAGACCGTCAGCAACATGCAGGAAG
TGATGGCGCGCGGCGGCAAGGTCGTACTCATCTCTGACGCCGACGGCATCGCCGAGGCGGGCGACGGCTGCATGGCGACG
ATCGAAATGCCCAAGGTCCACCCGCTGATCGCGCCGCTGGTCTATGCGGTGCCGGTGCAGCTTCTCGCCTATCATGTCGC
GGTGGCGAAGGGCACCGACGTCGATCAGCCGCGTAATCTGGCGAAGTCGGTGACGGTGGAGTGA

Upstream 100 bases:

>100_bases
GCGCGGACGCGTTCTCATCACCCGTAATATCAAGGATTTTCCGGCGAATATGCCGGGCATCCGTGTCCCCTATACGCTCT
AAGACGAAAGCCAGACCCAC

Downstream 100 bases:

>100_bases
CGCCCGCAGCGATTGTGTCACTTCGCGCGACGTATCAGCATCAACGAAGGGCGCGTGAACCCCTTGTTTGCCTGAAGCCT
GGCCAGTGCAGAAAACCGAT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MCGIIGIIGKDQVAERLVDGLRRMEYRGYDSAGVCTVEGGQLIRRRAEGKLANLVKELAGNPAPGTVGIAHTRWATHGAP
TTSNAHPHATAEVALVHNGIIENFKPLREGLQARGRTFESETDTEVVAHLVSEQVEAGKSPTEAVQAILPALRGAFALAI
AFRQHPDLLIGARLGSPLVVGYGEGETFLGSDALALAPLTQRIAYLDEGDWVVITRDGAQIFDSENNPVEREVTTSGVTA
AAVEKGNYRHFMQKEIFEQPTVVAQTLSSYIRPLEQTVALPQMDFDLSAIDRITIVACGTSFYAGMVAKYWFETFARVPV
DIDVASEFRYRDPVLQPGGLALFISQSGETADTLAALRHCKANGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTK
AFTCQLAVLAALAAHLALKKGKLSAAEEREIVKHLVEAPAALNAALAHDEDIAAMAHLIAPARDVLYLGRGPDYPLALEG
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVMARGGKVVLISDADGIAEAGDGCMAT
IEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_607_residues
MCGIIGIIGKDQVAERLVDGLRRMEYRGYDSAGVCTVEGGQLIRRRAEGKLANLVKELAGNPAPGTVGIAHTRWATHGAP
TTSNAHPHATAEVALVHNGIIENFKPLREGLQARGRTFESETDTEVVAHLVSEQVEAGKSPTEAVQAILPALRGAFALAI
AFRQHPDLLIGARLGSPLVVGYGEGETFLGSDALALAPLTQRIAYLDEGDWVVITRDGAQIFDSENNPVEREVTTSGVTA
AAVEKGNYRHFMQKEIFEQPTVVAQTLSSYIRPLEQTVALPQMDFDLSAIDRITIVACGTSFYAGMVAKYWFETFARVPV
DIDVASEFRYRDPVLQPGGLALFISQSGETADTLAALRHCKANGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTK
AFTCQLAVLAALAAHLALKKGKLSAAEEREIVKHLVEAPAALNAALAHDEDIAAMAHLIAPARDVLYLGRGPDYPLALEG
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVMARGGKVVLISDADGIAEAGDGCMAT
IEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNLAKSVTVE
>Mature_607_residues
MCGIIGIIGKDQVAERLVDGLRRMEYRGYDSAGVCTVEGGQLIRRRAEGKLANLVKELAGNPAPGTVGIAHTRWATHGAP
TTSNAHPHATAEVALVHNGIIENFKPLREGLQARGRTFESETDTEVVAHLVSEQVEAGKSPTEAVQAILPALRGAFALAI
AFRQHPDLLIGARLGSPLVVGYGEGETFLGSDALALAPLTQRIAYLDEGDWVVITRDGAQIFDSENNPVEREVTTSGVTA
AAVEKGNYRHFMQKEIFEQPTVVAQTLSSYIRPLEQTVALPQMDFDLSAIDRITIVACGTSFYAGMVAKYWFETFARVPV
DIDVASEFRYRDPVLQPGGLALFISQSGETADTLAALRHCKANGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTK
AFTCQLAVLAALAAHLALKKGKLSAAEEREIVKHLVEAPAALNAALAHDEDIAAMAHLIAPARDVLYLGRGPDYPLALEG
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVMARGGKVVLISDADGIAEAGDGCMAT
IEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=689, Percent_Identity=35.7039187227866, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI205277386, Length=688, Percent_Identity=36.3372093023256, Blast_Score=396, Evalue=1e-110,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=53.1914893617021, Blast_Score=623, Evalue=1e-179,
Organism=Escherichia coli, GI1788651, Length=259, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082251, Length=312, Percent_Identity=25, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17532899, Length=717, Percent_Identity=34.4490934449093, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17539970, Length=713, Percent_Identity=33.6605890603086, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17532897, Length=434, Percent_Identity=38.2488479262673, Blast_Score=290, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6322745, Length=444, Percent_Identity=36.9369369369369, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323731, Length=437, Percent_Identity=30.2059496567506, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323730, Length=233, Percent_Identity=33.9055793991416, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323958, Length=167, Percent_Identity=26.9461077844311, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357745, Length=686, Percent_Identity=35.5685131195335, Blast_Score=409, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 64600; Mature: 64600

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIIGIIGKDQVAERLVDGLRRMEYRGYDSAGVCTVEGGQLIRRRAEGKLANLVKELAG
CCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHHCC
NPAPGTVGIAHTRWATHGAPTTSNAHPHATAEVALVHNGIIENFKPLREGLQARGRTFES
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCC
ETDTEVVAHLVSEQVEAGKSPTEAVQAILPALRGAFALAIAFRQHPDLLIGARLGSPLVV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEE
GYGEGETFLGSDALALAPLTQRIAYLDEGDWVVITRDGAQIFDSENNPVEREVTTSGVTA
EECCCCCEECCCCHHHHHHHHHHHEECCCCEEEEECCCHHEECCCCCCCCCEECCCCCEE
AAVEKGNYRHFMQKEIFEQPTVVAQTLSSYIRPLEQTVALPQMDFDLSAIDRITIVACGT
EECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCEEEEEEECC
SFYAGMVAKYWFETFARVPVDIDVASEFRYRDPVLQPGGLALFISQSGETADTLAALRHC
HHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
KANGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTKAFTCQLAVLAALAAHLALKK
CCCCCEEEEEEECCCHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GKLSAAEEREIVKHLVEAPAALNAALAHDEDIAAMAHLIAPARDVLYLGRGPDYPLALEG
CCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEECC
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVMARGGK
CEEEEHEEEEEECCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
VVLISDADGIAEAGDGCMATIEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNL
EEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AKSVTVE
HHHCCCC
>Mature Secondary Structure
MCGIIGIIGKDQVAERLVDGLRRMEYRGYDSAGVCTVEGGQLIRRRAEGKLANLVKELAG
CCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHHCC
NPAPGTVGIAHTRWATHGAPTTSNAHPHATAEVALVHNGIIENFKPLREGLQARGRTFES
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCC
ETDTEVVAHLVSEQVEAGKSPTEAVQAILPALRGAFALAIAFRQHPDLLIGARLGSPLVV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEE
GYGEGETFLGSDALALAPLTQRIAYLDEGDWVVITRDGAQIFDSENNPVEREVTTSGVTA
EECCCCCEECCCCHHHHHHHHHHHEECCCCEEEEECCCHHEECCCCCCCCCEECCCCCEE
AAVEKGNYRHFMQKEIFEQPTVVAQTLSSYIRPLEQTVALPQMDFDLSAIDRITIVACGT
EECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCEEEEEEECC
SFYAGMVAKYWFETFARVPVDIDVASEFRYRDPVLQPGGLALFISQSGETADTLAALRHC
HHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
KANGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTKAFTCQLAVLAALAAHLALKK
CCCCCEEEEEEECCCHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GKLSAAEEREIVKHLVEAPAALNAALAHDEDIAAMAHLIAPARDVLYLGRGPDYPLALEG
CCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEECC
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVMARGGK
CEEEEHEEEEEECCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
VVLISDADGIAEAGDGCMATIEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNL
EEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AKSVTVE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA