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The map label for this gene is gap [H]

Identifier: 103486805

GI number: 103486805

Start: 1376952

End: 1377959

Strand: Reverse

Name: gap [H]

Synonym: Sala_1319

Alternate gene names: 103486805

Gene position: 1377959-1376952 (Counterclockwise)

Preceding gene: 103486806

Following gene: 103486804

Centisome position: 41.19

GC content: 64.68

Gene sequence:

>1008_bases
ATGGCAGTGAAAGTCGCAATCAACGGTTTCGGACGCATCGGCCGCCTCGTGGCGCGCGCCATTCTCGAACGTCCCGACTG
CGGGCTCGAACTGGTTGCGATCAACGACCTTGCCGATGCCAAGGCGAACGCCCTGCTGTTCAAGCGCGACAGCGTCCATG
GCCCGTTCCCTGGCGAGGTTTCGGCCGACGGCGACCAGATGATCGTGGGCGGCAAGGCGATCCGCGTAACGAAGGAACGC
GATCCCGCGAATCTGCCGCACGGCGAACTGGGTATCGACATCGCGCTCGAATGCACGGGCTTTTTTACCGACCGCGAGAG
CGCGTCGAAGCATCTGGCCGCCGGCGCCAAGCGCGTCCTCATCTCGGCCCCCGCGAAGGGCGCCGACCTGACCGTCGTTT
ACGGGGTCAATCACGACAAGCTGACCGCCGAACATGTCGTCGTGTCGAACGCGAGCTGCACGACCAACTGCCTCGCGCCG
GTCGCCAAGGTGCTCAACGACACGCTGGGCATCGAGCGCGGGCTGATGACCACGGTTCACGCCTATACCAATGACCAGAA
GATTCTCGACCAGATCCACAGCGACATGCGCCGCGCGCGCGCCGCGGGTATGTCGATCATCCCGACAACGACGGGCGCCG
CGCGCGCGGTCGGCGAAGTGCTGCCCGAACTCAAGGGCAAGCTCGACGGATCGGCGATCCGCGTGCCGACGCCGAACGTC
AGCCTCGTCGACCTGACCTTCACGCCGAAGCGCGACACGAGCGTCGCGGAAGTGAACCAGATCCTGAAGGATGCGTCGGA
GGGCGCGCTCAAGGGCGTGCTGGCCTTCTCTGACGAGCCGCTGGTGTCGATCGATTATAATCATTGCCCGGCAAGCTCGA
CGGTCGACAGCCTCGAAACCGCGGTGCTCGAGGGCAAGCTGGTGCGCGTGGTCAGCTGGTACGACAATGAATGGGGCTTC
TCGAACCGCATGGTCGACACCGCGGGCGTGATCGCGAAGCTGCTGTAA

Upstream 100 bases:

>100_bases
CAGGCATTTCGGCCTTACCGCCGATGCCATCACCCCCCAGATCCTGGCCCGGCTGAGCCATTAAGGACCGGCCGACCATT
CGCAGAAAGGACAATTCGAC

Downstream 100 bases:

>100_bases
GCATATCCGTGTGCCCCCGCGAAGGCGGGGGCCGATCACCGACGCTATCAGATGGCGGGATGGTGGCGGGTGACGAAAGC
GCAGGAGATGGGCCCCCGCC

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVKVAINGFGRIGRLVARAILERPDCGLELVAINDLADAKANALLFKRDSVHGPFPGEVSADGDQMIVGGKAIRVTKER
DPANLPHGELGIDIALECTGFFTDRESASKHLAAGAKRVLISAPAKGADLTVVYGVNHDKLTAEHVVVSNASCTTNCLAP
VAKVLNDTLGIERGLMTTVHAYTNDQKILDQIHSDMRRARAAGMSIIPTTTGAARAVGEVLPELKGKLDGSAIRVPTPNV
SLVDLTFTPKRDTSVAEVNQILKDASEGALKGVLAFSDEPLVSIDYNHCPASSTVDSLETAVLEGKLVRVVSWYDNEWGF
SNRMVDTAGVIAKLL

Sequences:

>Translated_335_residues
MAVKVAINGFGRIGRLVARAILERPDCGLELVAINDLADAKANALLFKRDSVHGPFPGEVSADGDQMIVGGKAIRVTKER
DPANLPHGELGIDIALECTGFFTDRESASKHLAAGAKRVLISAPAKGADLTVVYGVNHDKLTAEHVVVSNASCTTNCLAP
VAKVLNDTLGIERGLMTTVHAYTNDQKILDQIHSDMRRARAAGMSIIPTTTGAARAVGEVLPELKGKLDGSAIRVPTPNV
SLVDLTFTPKRDTSVAEVNQILKDASEGALKGVLAFSDEPLVSIDYNHCPASSTVDSLETAVLEGKLVRVVSWYDNEWGF
SNRMVDTAGVIAKLL
>Mature_334_residues
AVKVAINGFGRIGRLVARAILERPDCGLELVAINDLADAKANALLFKRDSVHGPFPGEVSADGDQMIVGGKAIRVTKERD
PANLPHGELGIDIALECTGFFTDRESASKHLAAGAKRVLISAPAKGADLTVVYGVNHDKLTAEHVVVSNASCTTNCLAPV
AKVLNDTLGIERGLMTTVHAYTNDQKILDQIHSDMRRARAAGMSIIPTTTGAARAVGEVLPELKGKLDGSAIRVPTPNVS
LVDLTFTPKRDTSVAEVNQILKDASEGALKGVLAFSDEPLVSIDYNHCPASSTVDSLETAVLEGKLVRVVSWYDNEWGFS
NRMVDTAGVIAKLL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=326, Percent_Identity=48.159509202454, Blast_Score=301, Evalue=8e-82,
Organism=Homo sapiens, GI7657116, Length=325, Percent_Identity=44.3076923076923, Blast_Score=267, Evalue=8e-72,
Organism=Escherichia coli, GI1789295, Length=336, Percent_Identity=48.8095238095238, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=51.1976047904192, Blast_Score=328, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI17534677, Length=336, Percent_Identity=50.5952380952381, Blast_Score=307, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI17534679, Length=336, Percent_Identity=50.297619047619, Blast_Score=307, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=48.8095238095238, Blast_Score=295, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=48.8095238095238, Blast_Score=294, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=52.2522522522522, Blast_Score=330, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=51.9519519519519, Blast_Score=328, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=49.8498498498498, Blast_Score=319, Evalue=4e-88,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=49.5384615384615, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=49.5384615384615, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=49.5384615384615, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=49.5384615384615, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI19922412, Length=324, Percent_Identity=45.3703703703704, Blast_Score=278, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35556; Mature: 35425

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVAINGFGRIGRLVARAILERPDCGLELVAINDLADAKANALLFKRDSVHGPFPGEV
CEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCC
SADGDQMIVGGKAIRVTKERDPANLPHGELGIDIALECTGFFTDRESASKHLAAGAKRVL
CCCCCEEEECCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHCCCCEEE
ISAPAKGADLTVVYGVNHDKLTAEHVVVSNASCTTNCLAPVAKVLNDTLGIERGLMTTVH
EECCCCCCCEEEEEECCCCCEEECEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHEEEE
AYTNDQKILDQIHSDMRRARAAGMSIIPTTTGAARAVGEVLPELKGKLDGSAIRVPTPNV
ECCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEECCCCC
SLVDLTFTPKRDTSVAEVNQILKDASEGALKGVLAFSDEPLVSIDYNHCPASSTVDSLET
EEEEEEECCCCCCCHHHHHHHHHHCCCHHHEEEEEECCCCEEEEECCCCCCCCHHHHHHH
AVLEGKLVRVVSWYDNEWGFSNRMVDTAGVIAKLL
HHHCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AVKVAINGFGRIGRLVARAILERPDCGLELVAINDLADAKANALLFKRDSVHGPFPGEV
EEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCC
SADGDQMIVGGKAIRVTKERDPANLPHGELGIDIALECTGFFTDRESASKHLAAGAKRVL
CCCCCEEEECCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHCCCCEEE
ISAPAKGADLTVVYGVNHDKLTAEHVVVSNASCTTNCLAPVAKVLNDTLGIERGLMTTVH
EECCCCCCCEEEEEECCCCCEEECEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHEEEE
AYTNDQKILDQIHSDMRRARAAGMSIIPTTTGAARAVGEVLPELKGKLDGSAIRVPTPNV
ECCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEECCCCC
SLVDLTFTPKRDTSVAEVNQILKDASEGALKGVLAFSDEPLVSIDYNHCPASSTVDSLET
EEEEEEECCCCCCCHHHHHHHHHHCCCHHHEEEEEECCCCEEEEECCCCCCCCHHHHHHH
AVLEGKLVRVVSWYDNEWGFSNRMVDTAGVIAKLL
HHHCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3680173 [H]