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The map label for this gene is nuoL [H]

Identifier: 103486784

GI number: 103486784

Start: 1357865

End: 1359910

Strand: Reverse

Name: nuoL [H]

Synonym: Sala_1298

Alternate gene names: 103486784

Gene position: 1359910-1357865 (Counterclockwise)

Preceding gene: 103486785

Following gene: 103486783

Centisome position: 40.65

GC content: 63.54

Gene sequence:

>2046_bases
GTGATTCAGGCGATCGTTTTCCTGCCGCTGCTCGCGGCGCTTGTTGCAGGGCTTGGCCAGCGCGCCATCGGCCCCTTCGC
ATCGAAGCTGGTCACGACCGGCGCGCTGTTCACCAGCTGCGCGCTCAGCTGGCCGATCTTCCTGTCCTTCGTGGCGGGGA
CCGGCGAGGCCGAAGTCGTCACCGTGCTGCATTGGGTGTCGTCGGGCGCACTCCAGTTCGACTGGGCGCTGCGCGTCGAC
ACGCTGACCGCGGTGATGCTCGTCGTCATCACGACGGTGTCGGCGCTCGTCCACCTCTATAGCTGGGGCTATATGGAGGA
AGACCCGGACCAGCCGCGCTTCTTCGCTTACCTGTCGCTCTTCACCTTTGCGATGCTGATGCTGGTGACCGCAGACAATC
TGGTCCAGATGTTCTTCGGCTGGGAAGGCGTCGGCCTTGCCTCCTATCTGCTCATCGGCTTCTGGTACAAGAAACCGAGC
GCCAATGCCGCGGCGATCAAGGCGTTCGTCGTCAACCGCGTCGGCGATTTGGGCTTCATGCTCGGCATCTTCGGCACCTT
CCTGGTGTTTGGCACCGTCTCGATCCCCGAGATCCTTGCGGCCGCGCCGGGCATGGCGGGTTCGACGATCGGCTTTTTCG
GCTATCGCGTCGATACGATGACCTTGCTCTGCCTGCTGCTGTTCATCGGCGCGATGGGCAAGTCGGCGCAGCTCGGGCTC
CACACCTGGCTGCCCGACGCGATGGAGGGTCCGACGCCGGTGTCGGCGCTGATCCACGCCGCGACGATGGTCACGGCGGG
CGTCTTCATGGTGTGCCGCCTTTCGCCGATGTTCGAGACCGCGCCGATCGCGCTGGGCGTCGTCACCTTCGTCGGCGCCG
CGACCTGCCTGTTCGCCGCGACTGTCGGCACGACGCAATGGGACATCAAGCGCGTCATCGCCTATTCGACATGCTCGCAA
CTCGGCTACATGTTCTTCGCCGCGGGCGTCGGCGCCTATGGCGCGGCGATGTTCCACCTGTTCACGCACGCCTTCTTCAA
GGCTCTGCTGTTCCTCGGCGCGGGGTCGGTGATCCATGCGATGCACCACGAACAGGATATGCGTTATTACGGCGGCCTTC
GGAAACATATCCCGCTCACCTATTGGGCGATGATGATGGGCACGCTGGCGATCACCGGCGTCGGCATCGCCGGGGTCGCG
GGCTTCGCGGGCTTCCATTCGAAGGACGGCATCCTCGAGGCGGCCTTTGCTGCCGGCGGCGGCGGCGTGGTCGCTTTCTG
GGTCGGTATTTTCGCCGCACTGCTGACGAGCTTCTATTCGTGGCGCCTCGTTTTCCTGACCTTCTATGGCAAGCCGCGGT
GGGAAGCGAGCGAGCATATTCAGCATGCGGTGCATGGCGAACATGAAGAGCCCTCGGATGAACATTCGAGCGGCAATCAT
GCGCCTCATCACCACGATCCCCACGGCGACGGCACCGCGGGCTACCATCCGCACGAAAGCCCGCTGTCGATGCTGATCCC
GCTCGGCGTGCTGTCGCTCGGCGCGGTGTTCGCAGGCTTCGTCTTCGCGCACCCCTTCATCTATCCCGAAGAAGGCAAGA
CTTTCTGGGCGGACAGCATCGCGTTCGACGAGCATCTGATGCACCTCGCGCACGAAGTGCCGACCTGGGTGAAGTGGGCG
CCGTTCGCGGTGATGGCGATCGGGCTGTTCCTCGCGTGGAACAGCTATGTCCGCAACACCAGCCTGCCGGCGCGCTTTGC
GGCGCAATTCCGGCTGCTCTACCAGTTCCTGTACAATAAATGGTATTTCGACGAGCTCTACAACATCCTCTTCGTAAAGC
CCGCCTTTGCGATCGGCCGCTTCTTCTGGAAGCGCGGGGATGAAGGCACCATCGACCGCTTCGGTCCCGATGGTGCCGCG
GCGCTCGTCGCCGGGGGGACGCGGCTCGCGGTCCGGCTGCAATCGGGTTATGTTTATGGATATGCGTTTGTGATGCTGCT
CGGTCTTGTCGGCCTCGCCAGCTGGGCCATGGTGAATTTCCTGTGA

Upstream 100 bases:

>100_bases
GCGGGCGAAGCGGCGATCGGTCTGGCCATCCTTGTTATCTATTTCCGCGGCCGCGGCACCATTGCCGTCGACGATGCCAA
CCGGATGAAGGGGTAAGCCG

Downstream 100 bases:

>100_bases
GCGGCTTTCCGATCCTTTCGCTGATGCTGGCGGTCCCGCTGATCGCCGCCATCCTCTGCCTCTATGCGGGCGACCGTAAC
GCACGTGTTATCGCGCTCGC

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MIQAIVFLPLLAALVAGLGQRAIGPFASKLVTTGALFTSCALSWPIFLSFVAGTGEAEVVTVLHWVSSGALQFDWALRVD
TLTAVMLVVITTVSALVHLYSWGYMEEDPDQPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPS
ANAAAIKAFVVNRVGDLGFMLGIFGTFLVFGTVSIPEILAAAPGMAGSTIGFFGYRVDTMTLLCLLLFIGAMGKSAQLGL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVCRLSPMFETAPIALGVVTFVGAATCLFAATVGTTQWDIKRVIAYSTCSQ
LGYMFFAAGVGAYGAAMFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRYYGGLRKHIPLTYWAMMMGTLAITGVGIAGVA
GFAGFHSKDGILEAAFAAGGGGVVAFWVGIFAALLTSFYSWRLVFLTFYGKPRWEASEHIQHAVHGEHEEPSDEHSSGNH
APHHHDPHGDGTAGYHPHESPLSMLIPLGVLSLGAVFAGFVFAHPFIYPEEGKTFWADSIAFDEHLMHLAHEVPTWVKWA
PFAVMAIGLFLAWNSYVRNTSLPARFAAQFRLLYQFLYNKWYFDELYNILFVKPAFAIGRFFWKRGDEGTIDRFGPDGAA
ALVAGGTRLAVRLQSGYVYGYAFVMLLGLVGLASWAMVNFL

Sequences:

>Translated_681_residues
MIQAIVFLPLLAALVAGLGQRAIGPFASKLVTTGALFTSCALSWPIFLSFVAGTGEAEVVTVLHWVSSGALQFDWALRVD
TLTAVMLVVITTVSALVHLYSWGYMEEDPDQPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPS
ANAAAIKAFVVNRVGDLGFMLGIFGTFLVFGTVSIPEILAAAPGMAGSTIGFFGYRVDTMTLLCLLLFIGAMGKSAQLGL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVCRLSPMFETAPIALGVVTFVGAATCLFAATVGTTQWDIKRVIAYSTCSQ
LGYMFFAAGVGAYGAAMFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRYYGGLRKHIPLTYWAMMMGTLAITGVGIAGVA
GFAGFHSKDGILEAAFAAGGGGVVAFWVGIFAALLTSFYSWRLVFLTFYGKPRWEASEHIQHAVHGEHEEPSDEHSSGNH
APHHHDPHGDGTAGYHPHESPLSMLIPLGVLSLGAVFAGFVFAHPFIYPEEGKTFWADSIAFDEHLMHLAHEVPTWVKWA
PFAVMAIGLFLAWNSYVRNTSLPARFAAQFRLLYQFLYNKWYFDELYNILFVKPAFAIGRFFWKRGDEGTIDRFGPDGAA
ALVAGGTRLAVRLQSGYVYGYAFVMLLGLVGLASWAMVNFL
>Mature_681_residues
MIQAIVFLPLLAALVAGLGQRAIGPFASKLVTTGALFTSCALSWPIFLSFVAGTGEAEVVTVLHWVSSGALQFDWALRVD
TLTAVMLVVITTVSALVHLYSWGYMEEDPDQPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPS
ANAAAIKAFVVNRVGDLGFMLGIFGTFLVFGTVSIPEILAAAPGMAGSTIGFFGYRVDTMTLLCLLLFIGAMGKSAQLGL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVCRLSPMFETAPIALGVVTFVGAATCLFAATVGTTQWDIKRVIAYSTCSQ
LGYMFFAAGVGAYGAAMFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRYYGGLRKHIPLTYWAMMMGTLAITGVGIAGVA
GFAGFHSKDGILEAAFAAGGGGVVAFWVGIFAALLTSFYSWRLVFLTFYGKPRWEASEHIQHAVHGEHEEPSDEHSSGNH
APHHHDPHGDGTAGYHPHESPLSMLIPLGVLSLGAVFAGFVFAHPFIYPEEGKTFWADSIAFDEHLMHLAHEVPTWVKWA
PFAVMAIGLFLAWNSYVRNTSLPARFAAQFRLLYQFLYNKWYFDELYNILFVKPAFAIGRFFWKRGDEGTIDRFGPDGAA
ALVAGGTRLAVRLQSGYVYGYAFVMLLGLVGLASWAMVNFL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=411, Percent_Identity=40.1459854014599, Blast_Score=300, Evalue=2e-81,
Organism=Escherichia coli, GI1788614, Length=622, Percent_Identity=38.5852090032154, Blast_Score=344, Evalue=8e-96,
Organism=Escherichia coli, GI1788829, Length=444, Percent_Identity=31.7567567567568, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1788827, Length=348, Percent_Identity=30.1724137931034, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788831, Length=344, Percent_Identity=29.6511627906977, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788613, Length=405, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI145693160, Length=378, Percent_Identity=24.8677248677249, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI2367154, Length=243, Percent_Identity=26.7489711934156, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 74087; Mature: 74087

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAIVFLPLLAALVAGLGQRAIGPFASKLVTTGALFTSCALSWPIFLSFVAGTGEAEVV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
TVLHWVSSGALQFDWALRVDTLTAVMLVVITTVSALVHLYSWGYMEEDPDQPRFFAYLSL
HHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYKKPSANAAAIKAFVVNRVGDLGFM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LGIFGTFLVFGTVSIPEILAAAPGMAGSTIGFFGYRVDTMTLLCLLLFIGAMGKSAQLGL
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVCRLSPMFETAPIALGVVTFVGAATCLFAA
HHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TVGTTQWDIKRVIAYSTCSQLGYMFFAAGVGAYGAAMFHLFTHAFFKALLFLGAGSVIHA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
MHHEQDMRYYGGLRKHIPLTYWAMMMGTLAITGVGIAGVAGFAGFHSKDGILEAAFAAGG
HHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHCCC
GGVVAFWVGIFAALLTSFYSWRLVFLTFYGKPRWEASEHIQHAVHGEHEEPSDEHSSGNH
CHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
APHHHDPHGDGTAGYHPHESPLSMLIPLGVLSLGAVFAGFVFAHPFIYPEEGKTFWADSI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEHHHH
AFDEHLMHLAHEVPTWVKWAPFAVMAIGLFLAWNSYVRNTSLPARFAAQFRLLYQFLYNK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
WYFDELYNILFVKPAFAIGRFFWKRGDEGTIDRFGPDGAAALVAGGTRLAVRLQSGYVYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCHHH
YAFVMLLGLVGLASWAMVNFL
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]