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The map label for this gene is caiD [C]

Identifier: 103486366

GI number: 103486366

Start: 882964

End: 883716

Strand: Reverse

Name: caiD [C]

Synonym: Sala_0876

Alternate gene names: 103486366

Gene position: 883716-882964 (Counterclockwise)

Preceding gene: 103486367

Following gene: 103486365

Centisome position: 26.42

GC content: 64.67

Gene sequence:

>753_bases
ATGAGCAAACCGCTCGTCATCCGGGAGGACTCCGGCGGCATCTGTACGCTGACGCTCAACCGCCCCGACAAGCGCAATGC
CATCAACCGTGACCTGTTCCGTGCCTTTCGTGCCCACATCCGCGACCTCGAAAGCGATCGCGATACGGGGCTGGTGGTCA
TCACCGGCGCGGGCGGGCATTTCTGTGCCGGTCACGACCTGAAACAGGCGCCGCACGCCGATGCACTCGGTTGGCTTCGC
CAGGAAATGCTGATTCTGGAACGCCTGACCAAGCTGCGCCAGCCGGTCATCGCAAAGGTTTCCGGGAGCTGCTATACCGG
CGGCCTCGAACTTGCGCTGGCCGCCGATTTCATCGTCTGCGGCGACAGCGCCCGTTTCGCCGACACCCACGGCAAATGGG
GCCTTGTCCCCGGCTGGGGCCTGTCCCAGCGCCTGCCCCGCCGGATCGGTCAGGCCAGGGCACTGGAGATGATGTTCACC
AGTCGTCCCTATAGCGGCGCCGAGGCAGCGGCGATGGGCCTTGCCAATCATTGCGTCGCCGACGCCGATCTGGACGCGAA
AGTGACCGAACTCGCCGCGCTGATCCTGGACAACAGCCGCCACAGCAATGCCGAGAACAAGCGGTTGGTCTATGACACCG
ACGGCATGGCGCTGGACACCGGCCTTTCCCATGAATTGATGCGTAATGCGGGGTTCGACCCGGCCATGCGGCAAAAGGGC
GAAGCGATCGGCAGCGCGCGAAAGGGCGGCTGA

Upstream 100 bases:

>100_bases
TGATGCCCGAGTTTGTGCCGATCCGCGAACAATTTGGACGGCGTGCCGTCGATAGCGGCAGCGCCCGCGCCGCCATTGCC
AAAACCAGAGGGGACCGGCC

Downstream 100 bases:

>100_bases
TGGACATCGGCTTTTCCCCCGATGAAGCCCGATTCCGCGACGAATGCCGCGAATGGCTGAACGCCAATGTGCCGACCGAA
AAGCGCCCCATCGACGCCGC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSKPLVIREDSGGICTLTLNRPDKRNAINRDLFRAFRAHIRDLESDRDTGLVVITGAGGHFCAGHDLKQAPHADALGWLR
QEMLILERLTKLRQPVIAKVSGSCYTGGLELALAADFIVCGDSARFADTHGKWGLVPGWGLSQRLPRRIGQARALEMMFT
SRPYSGAEAAAMGLANHCVADADLDAKVTELAALILDNSRHSNAENKRLVYDTDGMALDTGLSHELMRNAGFDPAMRQKG
EAIGSARKGG

Sequences:

>Translated_250_residues
MSKPLVIREDSGGICTLTLNRPDKRNAINRDLFRAFRAHIRDLESDRDTGLVVITGAGGHFCAGHDLKQAPHADALGWLR
QEMLILERLTKLRQPVIAKVSGSCYTGGLELALAADFIVCGDSARFADTHGKWGLVPGWGLSQRLPRRIGQARALEMMFT
SRPYSGAEAAAMGLANHCVADADLDAKVTELAALILDNSRHSNAENKRLVYDTDGMALDTGLSHELMRNAGFDPAMRQKG
EAIGSARKGG
>Mature_249_residues
SKPLVIREDSGGICTLTLNRPDKRNAINRDLFRAFRAHIRDLESDRDTGLVVITGAGGHFCAGHDLKQAPHADALGWLRQ
EMLILERLTKLRQPVIAKVSGSCYTGGLELALAADFIVCGDSARFADTHGKWGLVPGWGLSQRLPRRIGQARALEMMFTS
RPYSGAEAAAMGLANHCVADADLDAKVTELAALILDNSRHSNAENKRLVYDTDGMALDTGLSHELMRNAGFDPAMRQKGE
AIGSARKGG

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=210, Percent_Identity=31.9047619047619, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI70995211, Length=186, Percent_Identity=33.8709677419355, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI31542718, Length=231, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4502327, Length=177, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI20127408, Length=176, Percent_Identity=30.6818181818182, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI37594469, Length=196, Percent_Identity=29.0816326530612, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI37594471, Length=196, Percent_Identity=29.0816326530612, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI157694516, Length=184, Percent_Identity=25, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI213417737, Length=184, Percent_Identity=25, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI68989263, Length=205, Percent_Identity=26.3414634146341, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI221142681, Length=220, Percent_Identity=35.4545454545455, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787659, Length=227, Percent_Identity=31.7180616740088, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788597, Length=242, Percent_Identity=31.8181818181818, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788682, Length=189, Percent_Identity=33.8624338624339, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787660, Length=228, Percent_Identity=29.8245614035088, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082183, Length=236, Percent_Identity=25, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790281, Length=173, Percent_Identity=27.1676300578035, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=191, Percent_Identity=38.2198952879581, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25145438, Length=213, Percent_Identity=29.1079812206573, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=217, Percent_Identity=28.110599078341, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=192, Percent_Identity=30.7291666666667, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=193, Percent_Identity=25.9067357512953, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=181, Percent_Identity=28.7292817679558, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508953, Length=181, Percent_Identity=28.7292817679558, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=188, Percent_Identity=28.7234042553192, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25141363, Length=171, Percent_Identity=26.9005847953216, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=219, Percent_Identity=25.5707762557078, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=228, Percent_Identity=23.2456140350877, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=179, Percent_Identity=25.1396648044693, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=184, Percent_Identity=25.5434782608696, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24653139, Length=172, Percent_Identity=36.046511627907, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI20129971, Length=232, Percent_Identity=30.6034482758621, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24653477, Length=232, Percent_Identity=30.6034482758621, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357171, Length=231, Percent_Identity=27.7056277056277, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24650670, Length=194, Percent_Identity=32.4742268041237, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654903, Length=212, Percent_Identity=25.9433962264151, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19920382, Length=198, Percent_Identity=29.2929292929293, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19922422, Length=223, Percent_Identity=25.5605381165919, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28571730, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28571729, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27062; Mature: 26931

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPLVIREDSGGICTLTLNRPDKRNAINRDLFRAFRAHIRDLESDRDTGLVVITGAGGH
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
FCAGHDLKQAPHADALGWLRQEMLILERLTKLRQPVIAKVSGSCYTGGLELALAADFIVC
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEECCCCEEEEEEEEEE
GDSARFADTHGKWGLVPGWGLSQRLPRRIGQARALEMMFTSRPYSGAEAAAMGLANHCVA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
DADLDAKVTELAALILDNSRHSNAENKRLVYDTDGMALDTGLSHELMRNAGFDPAMRQKG
CCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEECCCCHHHHHHHCCCCHHHHHHH
EAIGSARKGG
HHHCCCCCCC
>Mature Secondary Structure 
SKPLVIREDSGGICTLTLNRPDKRNAINRDLFRAFRAHIRDLESDRDTGLVVITGAGGH
CCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
FCAGHDLKQAPHADALGWLRQEMLILERLTKLRQPVIAKVSGSCYTGGLELALAADFIVC
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEECCCCEEEEEEEEEE
GDSARFADTHGKWGLVPGWGLSQRLPRRIGQARALEMMFTSRPYSGAEAAAMGLANHCVA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
DADLDAKVTELAALILDNSRHSNAENKRLVYDTDGMALDTGLSHELMRNAGFDPAMRQKG
CCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEECCCCHHHHHHHCCCCHHHHHHH
EAIGSARKGG
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA