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The map label for this gene is etfA [H]

Identifier: 103485675

GI number: 103485675

Start: 182622

End: 183551

Strand: Direct

Name: etfA [H]

Synonym: Sala_0179

Alternate gene names: 103485675

Gene position: 182622-183551 (Clockwise)

Preceding gene: 103485674

Following gene: 103485676

Centisome position: 5.46

GC content: 64.62

Gene sequence:

>930_bases
ATGAAAACTCTGGTTTGGGTCGAACATGACGGCAAGGCCGTCAAGGATGCCACGCTCGCGGTGGTCACCGCCGCGTCGAA
GCTCGGCGAAGTCCATCTGCTCGTCGCCGGTTCGGGCGTCGATGCCGTTGCCAAGGAAGCCGCGCAGATCGCGGGCGTGG
GCAAGGTGCATGTCGCCGACAACGCCGCCTTCGATCACAATCTGCCCGAAAATGTCGCGCCGCTGATTGCCGAACTGATG
TCCTCGCACGACGCCTTCCTGGCGCCCGCGACGACGACCGGCAAGAATATCGCGCCGCGCGTCGCCGCGCTGCTCGACGT
GATGCAGATTTCGGAAATCCTGTCGGTCGAAGGCCCCAAGACCTTCACGCGCCCGATCTACGCCGGCAACGCGATCGCGA
CCGTCGAATCGTCGGATGCCAAGCTGGTCCTGACCGTTCGCGGCACCGCCTTCGAAAAGGCCGCGACCAGCGGCGGCGCG
GGCACGATCGAAGCCGTCGCGGCGGGCAGCGACGCCGGCATCTCGAGCTTCGTCGGCGCCGAAATCGCGAAGTCGGAGCG
CCCCGAACTCACCTCCGCGAAGATCATCGTCTCGGGCGGCCGGGCGCTGGGTTCGAGCGAGAAATATCAGGAAGTCATCG
TCCCGCTCGCCGACAAGCTGAACGCCGCGCTCGGTGCGTCGCGCGCCGCGGTCGATGCGGGCTATGTCCCCAACGATTAT
CAGGTCGGCCAGACCGGCAAGATCGTTGCGCCGGAGGTCTATTTTGCCATTGGCATCTCGGGCGCGATCCAGCATCTTGC
CGGCATGAAGGACTCGAAGACGATCGTCGCAATCAACAAGGATGAGGACGCGCCGATCTTTCAGGTCGCCGACCTCGGCC
TCGTCGCTGATTTGTTCAGTGCGGTGCCCGAGCTTACGGCCAAGATCTGA

Upstream 100 bases:

>100_bases
TAGTGTCGAGCGAAGTCGAGACACCCATCGGGACAGCGCAAGGTCGAGGGGCATCTCGACTTCGCTCGATGCGAACGGCA
AGGGATAAAGGATCAAGGTT

Downstream 100 bases:

>100_bases
CCCGCCGCACCATGGCCGGCCATCATCCTGGCGTGCCGGGCCTCGGCGATGCACCGTTCAACGCCGGTGGTCGCCGGTCG
GCACGGCCGGGGGCCGGCCG

Product: electron transfer flavoprotein, alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKTLVWVEHDGKAVKDATLAVVTAASKLGEVHLLVAGSGVDAVAKEAAQIAGVGKVHVADNAAFDHNLPENVAPLIAELM
SSHDAFLAPATTTGKNIAPRVAALLDVMQISEILSVEGPKTFTRPIYAGNAIATVESSDAKLVLTVRGTAFEKAATSGGA
GTIEAVAAGSDAGISSFVGAEIAKSERPELTSAKIIVSGGRALGSSEKYQEVIVPLADKLNAALGASRAAVDAGYVPNDY
QVGQTGKIVAPEVYFAIGISGAIQHLAGMKDSKTIVAINKDEDAPIFQVADLGLVADLFSAVPELTAKI

Sequences:

>Translated_309_residues
MKTLVWVEHDGKAVKDATLAVVTAASKLGEVHLLVAGSGVDAVAKEAAQIAGVGKVHVADNAAFDHNLPENVAPLIAELM
SSHDAFLAPATTTGKNIAPRVAALLDVMQISEILSVEGPKTFTRPIYAGNAIATVESSDAKLVLTVRGTAFEKAATSGGA
GTIEAVAAGSDAGISSFVGAEIAKSERPELTSAKIIVSGGRALGSSEKYQEVIVPLADKLNAALGASRAAVDAGYVPNDY
QVGQTGKIVAPEVYFAIGISGAIQHLAGMKDSKTIVAINKDEDAPIFQVADLGLVADLFSAVPELTAKI
>Mature_309_residues
MKTLVWVEHDGKAVKDATLAVVTAASKLGEVHLLVAGSGVDAVAKEAAQIAGVGKVHVADNAAFDHNLPENVAPLIAELM
SSHDAFLAPATTTGKNIAPRVAALLDVMQISEILSVEGPKTFTRPIYAGNAIATVESSDAKLVLTVRGTAFEKAATSGGA
GTIEAVAAGSDAGISSFVGAEIAKSERPELTSAKIIVSGGRALGSSEKYQEVIVPLADKLNAALGASRAAVDAGYVPNDY
QVGQTGKIVAPEVYFAIGISGAIQHLAGMKDSKTIVAINKDEDAPIFQVADLGLVADLFSAVPELTAKI

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=307, Percent_Identity=55.0488599348534, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI189181759, Length=267, Percent_Identity=56.5543071161049, Blast_Score=294, Evalue=8e-80,
Organism=Escherichia coli, GI1786226, Length=280, Percent_Identity=32.8571428571429, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787990, Length=270, Percent_Identity=30.7407407407407, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082157, Length=230, Percent_Identity=31.7391304347826, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=56.2700964630225, Blast_Score=314, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6325261, Length=320, Percent_Identity=42.8125, Blast_Score=252, Evalue=5e-68,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=57.2347266881029, Blast_Score=322, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=57.2347266881029, Blast_Score=322, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31534; Mature: 31534

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLVWVEHDGKAVKDATLAVVTAASKLGEVHLLVAGSGVDAVAKEAAQIAGVGKVHVAD
CCEEEEEECCCCCHHHHHHHEEHHHHHCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEC
NAAFDHNLPENVAPLIAELMSSHDAFLAPATTTGKNIAPRVAALLDVMQISEILSVEGPK
CCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TFTRPIYAGNAIATVESSDAKLVLTVRGTAFEKAATSGGAGTIEAVAAGSDAGISSFVGA
HHCCCEECCCEEEEEECCCCEEEEEEECCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHH
EIAKSERPELTSAKIIVSGGRALGSSEKYQEVIVPLADKLNAALGASRAAVDAGYVPNDY
HHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPEVYFAIGISGAIQHLAGMKDSKTIVAINKDEDAPIFQVADLGLVADLFS
EECCCCCEECCCEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHH
AVPELTAKI
HHHHHHCCC
>Mature Secondary Structure
MKTLVWVEHDGKAVKDATLAVVTAASKLGEVHLLVAGSGVDAVAKEAAQIAGVGKVHVAD
CCEEEEEECCCCCHHHHHHHEEHHHHHCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEC
NAAFDHNLPENVAPLIAELMSSHDAFLAPATTTGKNIAPRVAALLDVMQISEILSVEGPK
CCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TFTRPIYAGNAIATVESSDAKLVLTVRGTAFEKAATSGGAGTIEAVAAGSDAGISSFVGA
HHCCCEECCCEEEEEECCCCEEEEEEECCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHH
EIAKSERPELTSAKIIVSGGRALGSSEKYQEVIVPLADKLNAALGASRAAVDAGYVPNDY
HHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKIVAPEVYFAIGISGAIQHLAGMKDSKTIVAINKDEDAPIFQVADLGLVADLFS
EECCCCCEECCCEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHH
AVPELTAKI
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]