Click here to switch to the map view.

The map label for this gene is hslV [H]

Identifier: 99082689

GI number: 99082689

Start: 3019981

End: 3020538

Strand: Direct

Name: hslV [H]

Synonym: TM1040_2849

Alternate gene names: 99082689

Gene position: 3019981-3020538 (Clockwise)

Preceding gene: 99082687

Following gene: 99082690

Centisome position: 94.35

GC content: 62.01

Gene sequence:

>558_bases
ATGGCAGAGGATCAATTCCCCGGCTGGCATGGCACAACCATCATCGGGGTGCGCAAAGGGGACGAGGTAGTCGTCGCAGG
GGACGGTCAAGTCTCGCTCGGTCAGACCGTGATCAAGGGCAGTGCCCGCAAGGTGCGCCGCCTGTCGCCCGGCGGATATG
ACGTGGTGGCAGGCTTTGCCGGATCGACGGCGGATGCCTTCACCCTCCTTGAGCGGCTCGAAGCCAAACTGGAGGCAACG
CCAGGACAGCTTCAGCGCGCGAGTGTCGAGCTCGCCAAGGACTGGCGCACCGACAAATACCTGCAAAAACTAGAGGCAAT
GCTGATCGTCACCGATGGCAAGGATCTCTATGTCATCACCGGCGCTGGCGATGTGTTGGAACCAGAACATGATGTGGCCG
CCATCGGGTCTGGCGGCAACTTTGCCCTGGCAGCGGCGCGCGGCATGATGGACAGCGACCGCGACGCAGAAACAGTGGCC
CGTGACGCAATGGCGATCGCCTCTGACATCTGCGTCTACACCAACGGCAACCTCACGGTGGAGCGCATCGGCAAATGA

Upstream 100 bases:

>100_bases
AACTTTGCCTCGCGTCCTCCCCGAGGGATCATCCCCGACCCTGCCCTTGTGCCGCGTGGGGGATACTTCCATATAGGTCA
GCAAAGAAACGGAGGCTTTT

Downstream 100 bases:

>100_bases
TATCGCGCGATGACCTCAGGGCCGCGGTCGGGTCTGGCCTTCTGACCGAAGCACAGGCCGCGTCCTTGTCGGCCCTCGCG
GACAGCCGCCGCGGCGCGCG

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAEDQFPGWHGTTIIGVRKGDEVVVAGDGQVSLGQTVIKGSARKVRRLSPGGYDVVAGFAGSTADAFTLLERLEAKLEAT
PGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGKDLYVITGAGDVLEPEHDVAAIGSGGNFALAAARGMMDSDRDAETVA
RDAMAIASDICVYTNGNLTVERIGK

Sequences:

>Translated_185_residues
MAEDQFPGWHGTTIIGVRKGDEVVVAGDGQVSLGQTVIKGSARKVRRLSPGGYDVVAGFAGSTADAFTLLERLEAKLEAT
PGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGKDLYVITGAGDVLEPEHDVAAIGSGGNFALAAARGMMDSDRDAETVA
RDAMAIASDICVYTNGNLTVERIGK
>Mature_184_residues
AEDQFPGWHGTTIIGVRKGDEVVVAGDGQVSLGQTVIKGSARKVRRLSPGGYDVVAGFAGSTADAFTLLERLEAKLEATP
GQLQRASVELAKDWRTDKYLQKLEAMLIVTDGKDLYVITGAGDVLEPEHDVAAIGSGGNFALAAARGMMDSDRDAETVAR
DAMAIASDICVYTNGNLTVERIGK

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=173, Percent_Identity=54.9132947976879, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19570; Mature: 19439

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEDQFPGWHGTTIIGVRKGDEVVVAGDGQVSLGQTVIKGSARKVRRLSPGGYDVVAGFA
CCCCCCCCCCCCEEEEEECCCEEEEECCCCEECCHHHHHCCHHHHHHCCCCCEEEEEECC
GSTADAFTLLERLEAKLEATPGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGKDLYVIT
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHEEEEEEECCCEEEEEE
GAGDVLEPEHDVAAIGSGGNFALAAARGMMDSDRDAETVARDAMAIASDICVYTNGNLTV
CCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEEEECCCEEE
ERIGK
EECCC
>Mature Secondary Structure 
AEDQFPGWHGTTIIGVRKGDEVVVAGDGQVSLGQTVIKGSARKVRRLSPGGYDVVAGFA
CCCCCCCCCCCEEEEEECCCEEEEECCCCEECCHHHHHCCHHHHHHCCCCCEEEEEECC
GSTADAFTLLERLEAKLEATPGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGKDLYVIT
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHEEEEEEECCCEEEEEE
GAGDVLEPEHDVAAIGSGGNFALAAARGMMDSDRDAETVARDAMAIASDICVYTNGNLTV
CCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEEEECCCEEE
ERIGK
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA