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The map label for this gene is mhpD [H]

Identifier: 99082611

GI number: 99082611

Start: 2922245

End: 2923147

Strand: Reverse

Name: mhpD [H]

Synonym: TM1040_2771

Alternate gene names: 99082611

Gene position: 2923147-2922245 (Counterclockwise)

Preceding gene: 99082612

Following gene: 99082606

Centisome position: 91.32

GC content: 60.58

Gene sequence:

>903_bases
ATGCGCTGGCTTGAGGAGAAAAGAGGCATTTCGTTGAGAACATCGGGTCTGGTTGGAATCCTGACGATGAGCGTAGCTCT
GACCCTTGGAACAGATATTGCCCGGGCTGAATGCGCAAGCGAAGAAGAAGTTGCGCAGTTCGTGTCCGCCTATGTTGACC
GCCAGCCCGCGACCGCGCTTGGCGCAGGGGGGAGCATGGTGGATGCGCTCTGCACACAAGCGCGGGTCGCAGAAGCGCTC
TCGGAACACTTCGGCCCGGTGATTGGGTATAAGGCGGGATTGACCAGCGCGGCGGCACAGGCGCGTTTCGAGGCCAGCGA
ACCGGTTCGTGGTGTGCTTTATCGTGACATGATGCTGGAGAGTGGCGCGACGATCGAGATGCCTTGGGGCACGGTGCCCA
TGGTGGAAGCGGATCTGGTTCTTGAGATCGGAGACTCGGCGGTGAACTGGGCCACCACCCCCGAGGAAGTGATGCAGAAT
ATCAAAAGCATCCGGCCCTTTATCGAGTTGCCGGATCTGGCTTTGGCACCGGGTGAGCCGATGACGGTCGAGACGATCAC
CGCAATGGGAGTTGGTGCGCGCAAAGGCGTCTTGGGTGCAGAGGTGCCCGTCACGGATCCCACCGCGCTCACAGCGGCGT
TGGCGGAAATGACCGTGACTCTGCGCGACGGCACAGGTGATACGGTTGTCTCTGCTTCGGGTACCGCTGTTTTGGGCCAT
CCTGCAGAGACGATCCTTTGGCTGCACGAGGTGGGCGTGACCTTCAAGGCCGGTGATTTGGTCTCTGTCGGCTCTTTTGG
TCCCTTGGTGCCTCCGGCAGATCTTAGAGGAGGCGCGTCGGTGATCTATATGGGGCTGCCGGGGGATCCGGAGGTCTCCA
TTCGTTTTGCGCCGACATCCTGA

Upstream 100 bases:

>100_bases
TCGACCTTCCGAGCCCCGGGCCGGGCCATGCAACGCTTGTGGTGATCGATGCAGACGGGCAATCTGCACGGGTGACCGTT
GAAATCGAGGAGACCGGCTA

Downstream 100 bases:

>100_bases
CTGGGCCGAATGAACCCGTGAGACTGTTACACCTCGAGGGTTTTCACACCGGTCTTTGCCCGATGCGCCGCGCGAAGGGC
GCGGCGCCTAATCCAACGGG

Product: hydratase/decarboxylase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MRWLEEKRGISLRTSGLVGILTMSVALTLGTDIARAECASEEEVAQFVSAYVDRQPATALGAGGSMVDALCTQARVAEAL
SEHFGPVIGYKAGLTSAAAQARFEASEPVRGVLYRDMMLESGATIEMPWGTVPMVEADLVLEIGDSAVNWATTPEEVMQN
IKSIRPFIELPDLALAPGEPMTVETITAMGVGARKGVLGAEVPVTDPTALTAALAEMTVTLRDGTGDTVVSASGTAVLGH
PAETILWLHEVGVTFKAGDLVSVGSFGPLVPPADLRGGASVIYMGLPGDPEVSIRFAPTS

Sequences:

>Translated_300_residues
MRWLEEKRGISLRTSGLVGILTMSVALTLGTDIARAECASEEEVAQFVSAYVDRQPATALGAGGSMVDALCTQARVAEAL
SEHFGPVIGYKAGLTSAAAQARFEASEPVRGVLYRDMMLESGATIEMPWGTVPMVEADLVLEIGDSAVNWATTPEEVMQN
IKSIRPFIELPDLALAPGEPMTVETITAMGVGARKGVLGAEVPVTDPTALTAALAEMTVTLRDGTGDTVVSASGTAVLGH
PAETILWLHEVGVTFKAGDLVSVGSFGPLVPPADLRGGASVIYMGLPGDPEVSIRFAPTS
>Mature_300_residues
MRWLEEKRGISLRTSGLVGILTMSVALTLGTDIARAECASEEEVAQFVSAYVDRQPATALGAGGSMVDALCTQARVAEAL
SEHFGPVIGYKAGLTSAAAQARFEASEPVRGVLYRDMMLESGATIEMPWGTVPMVEADLVLEIGDSAVNWATTPEEVMQN
IKSIRPFIELPDLALAPGEPMTVETITAMGVGARKGVLGAEVPVTDPTALTAALAEMTVTLRDGTGDTVVSASGTAVLGH
PAETILWLHEVGVTFKAGDLVSVGSFGPLVPPADLRGGASVIYMGLPGDPEVSIRFAPTS

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 31210; Mature: 31210

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLEEKRGISLRTSGLVGILTMSVALTLGTDIARAECASEEEVAQFVSAYVDRQPATAL
CCCCHHHCCCEEECCCHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHCCCCCHHH
GAGGSMVDALCTQARVAEALSEHFGPVIGYKAGLTSAAAQARFEASEPVRGVLYRDMMLE
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHH
SGATIEMPWGTVPMVEADLVLEIGDSAVNWATTPEEVMQNIKSIRPFIELPDLALAPGEP
CCCEEEECCCCCCEEECEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHCCCCCEECCCCC
MTVETITAMGVGARKGVLGAEVPVTDPTALTAALAEMTVTLRDGTGDTVVSASGTAVLGH
CEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCEEEECCCCEEECC
PAETILWLHEVGVTFKAGDLVSVGSFGPLVPPADLRGGASVIYMGLPGDPEVSIRFAPTS
CHHHHHHHHHCCCEEECCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCC
>Mature Secondary Structure
MRWLEEKRGISLRTSGLVGILTMSVALTLGTDIARAECASEEEVAQFVSAYVDRQPATAL
CCCCHHHCCCEEECCCHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHCCCCCHHH
GAGGSMVDALCTQARVAEALSEHFGPVIGYKAGLTSAAAQARFEASEPVRGVLYRDMMLE
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHH
SGATIEMPWGTVPMVEADLVLEIGDSAVNWATTPEEVMQNIKSIRPFIELPDLALAPGEP
CCCEEEECCCCCCEEECEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHCCCCCEECCCCC
MTVETITAMGVGARKGVLGAEVPVTDPTALTAALAEMTVTLRDGTGDTVVSASGTAVLGH
CEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCEEEECCCCEEECC
PAETILWLHEVGVTFKAGDLVSVGSFGPLVPPADLRGGASVIYMGLPGDPEVSIRFAPTS
CHHHHHHHHHCCCEEECCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10537203 [H]