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The map label for this gene is aceE [H]

Identifier: 99082576

GI number: 99082576

Start: 2879545

End: 2881929

Strand: Reverse

Name: aceE [H]

Synonym: TM1040_2736

Alternate gene names: 99082576

Gene position: 2881929-2879545 (Counterclockwise)

Preceding gene: 99082577

Following gene: 99082572

Centisome position: 90.03

GC content: 63.44

Gene sequence:

>2385_bases
ATGTCCCAGAACATTGAACATCTGAGAACGGTGGAGCAGCGACTGTTGTGGCTGTCCCATTGGATGATCCACAACGCCAA
CCATTTGCGCGCCAAGGAGGACGGCATCAAGATCGGTGGCCATCAGGCGTCTTCTGCGTCGATGGTGTCGATCATGACCG
CGCTCTACTTCTCGGCGCTTCGCCCCGAGGACCGGGTGGCGGTCAAGCCGCATGCCTCGCCCATCTTTCACGCCATGCAA
TACCTCATGGGCCACCAGACTCGCGAGAAGATGGAGAACTTCCGCGGCTACGGCGGTGTGCAAAGCTACCCGAGCCGCAC
CAAGGATATTGACGATGTGGACTTCTCCACCGGCTCTGTGGGCCTTGGCGTGGGGATCACCGCGCTTGCGTCGATGGTGC
AGGATTTCATCACCGCAAAGGACTGGGGCGGCGATGTCACTCCGGGCCGGATGGTGGCGCTTGTGGGCGATGCCGAGCTT
GATGAGGGCAATATCTATGAGGTCTTGCAGGAGGGCTGGAAGAACGACCTGCGCAATACCTGGTGGATCATCGACTACAA
CCGCCAGAGCCTTGATGGCATCGTGCGCGAGGGGCTGTTTGGCCGGATCGAGAAAATCTTCGAGGCGTTCGGCTGGGATG
TGGTCCGGGTGAAATATGGCGCCCTCCAACGGGCCGCCTTTGAGGAACCCGGCGGCGAGGCCCTGCGTGACTGGATCGAC
GCCTGCCCGAACGTGGAATACTCCGCGCTGACCTATATGGGCGGGGCCAACTGGCGCAAACGCCTGATGGAGGATCTGGG
CGACCAGGGCGCGGTCTCGGCACTGATCGACAAGCGCAGCGACGCGGAACTGGCGGCGCTGATGGAGAACCTCGGCGGCA
ATTGCGTGGAAACGATGGCCGATACATTCGCCGCCATCGACCACGACCGTCCGACCTGCTTTCTGGCCTACACAATCAAG
GGCTGGGGCACGCCGATTGCGGGCCACAAGGACAACCACGGCGGCCTCATGACCAAGGCGCAGATGGCCGAGTGGCAGAC
CCATATGGGTGTGGCCGAGGGCGAGGAGTGGGAGCTGATGGCGACCGTTTCTGACACGAAGGGCTTTCAGGCCTATCTCG
ATCAGGTGCCGTTTTTTGCCAAGGGCGCGCGGCGCCACTCGGACGCGCGGCTTTCGGTGCCGGCGGTTGCGGTGGACACA
AGCCGCGAGATTTCAACGCAGATGGCCTTTGGCAAGATCCTTGACGATCTGGCGCGCGGCGACAGCGATCTTGCGGCGCG
GATCATGACCACCTCTCCGGATGTGACCGGCACCACGGGGCTTGGTCCATGGGTCAATCGCCGCAAGCTCTTTGCGCGAG
AGGCCCAAAAGGACGCCTTTATCGAACATCGCATTCCCTCGACGGCCAAGTGGAATTTTGACCCCAAGGGCCAGCATCTC
GAACTGGGTATCGCGGAGATGAACCTGTTCCTGCTGCTGGGCGCGGCGGGCCTGTCGCACAGTCTCTGGGGCAAGCGGGT
GATCCCGATTGGCACGGTTTATGATCCCTTTGTGCACCGGGGCTTGGATGCGCTCAACTACGCGTGCTATCAGGATGCGC
GCTTCATGATCGTCGGCACGCCCTCGGGGGTGACGCTGGCGCCGGAGGGCGGCGCGCATCAATCCGTGGGCACGCCCCTT
ACGGGCATGGCGCAGGATGGGCTTGCGAGTTTTGAACCGGCCTTTGCCGATGAGCTCGCGGTCATTATGGAATGGGCTTT
TGACTACATGCAGCGCGATGGCGAAGGCGACCCGGACGAGCGCACCTGGCTGCGCGATGAAACCGGCGGATCGGTCTATC
TGCGCCTGACCACCAAACCGCTCGAACAGCCGGGGCAACGGGTTGATGATGCCTTCCGTCAGGGGGCCATTGATGGGGCC
TATTGGCTGCGCAAGCCGGGGCCGAACTGTTCAGTTGTGATCGCCTATCAAGGTGCGGTCGCGGATGAGGCGATTGCGGC
GGCAGGTCTGGTCGGTGAGCATCGCCGCGACGTTGCCGTTCTGGCGGTGACCTCGGCGGATCGTCTCAATGCAGGCTGGA
CCGCCGCGCAGCGGGAACGGGCGCGGGGCAACCCGCAGGCGGTGTCGCATGTGGAGCGTCTCTTGGGGGAACTGCCTGCC
CATTGCACCCTGATCACCGCGATTGATGGTCATCCGGCGACGCTCTCGTGGCTGGGCTCGGTTGCAGGGCATCGGGTTGT
GTCGCATGGGGTCGAGCATTTCGGCCAGACCGGCACCATCGGGGATCTTTACCGTCACTTCGGTCTCGATCGGCACAGCC
TCGCGCGTTCCGTGGGCGAGCTCACCACGGGCGCGCGCCGCATCCCCGGCGGGCAGGCGGGCTAG

Upstream 100 bases:

>100_bases
GCTTGTCCGTGGGGCTTGAAGAGGTTTCGGACATTCTCGATGATCTTCAGCAAGCTCTGTCGCCTCAGATGCGTCAGGCT
GCCGAGTGAAAGGCGGGTCC

Downstream 100 bases:

>100_bases
GACCCTAGCGCAATACGGCGCTGCTCCACTCCTCCAGGAAGGCTGCCTTCTTGAGCGCGTCGAGATAGACCAGCAGCCCG
GGCCCCATGCGAATGCGACG

Product: transketolase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 793

Protein sequence:

>794_residues
MSQNIEHLRTVEQRLLWLSHWMIHNANHLRAKEDGIKIGGHQASSASMVSIMTALYFSALRPEDRVAVKPHASPIFHAMQ
YLMGHQTREKMENFRGYGGVQSYPSRTKDIDDVDFSTGSVGLGVGITALASMVQDFITAKDWGGDVTPGRMVALVGDAEL
DEGNIYEVLQEGWKNDLRNTWWIIDYNRQSLDGIVREGLFGRIEKIFEAFGWDVVRVKYGALQRAAFEEPGGEALRDWID
ACPNVEYSALTYMGGANWRKRLMEDLGDQGAVSALIDKRSDAELAALMENLGGNCVETMADTFAAIDHDRPTCFLAYTIK
GWGTPIAGHKDNHGGLMTKAQMAEWQTHMGVAEGEEWELMATVSDTKGFQAYLDQVPFFAKGARRHSDARLSVPAVAVDT
SREISTQMAFGKILDDLARGDSDLAARIMTTSPDVTGTTGLGPWVNRRKLFAREAQKDAFIEHRIPSTAKWNFDPKGQHL
ELGIAEMNLFLLLGAAGLSHSLWGKRVIPIGTVYDPFVHRGLDALNYACYQDARFMIVGTPSGVTLAPEGGAHQSVGTPL
TGMAQDGLASFEPAFADELAVIMEWAFDYMQRDGEGDPDERTWLRDETGGSVYLRLTTKPLEQPGQRVDDAFRQGAIDGA
YWLRKPGPNCSVVIAYQGAVADEAIAAAGLVGEHRRDVAVLAVTSADRLNAGWTAAQRERARGNPQAVSHVERLLGELPA
HCTLITAIDGHPATLSWLGSVAGHRVVSHGVEHFGQTGTIGDLYRHFGLDRHSLARSVGELTTGARRIPGGQAG

Sequences:

>Translated_794_residues
MSQNIEHLRTVEQRLLWLSHWMIHNANHLRAKEDGIKIGGHQASSASMVSIMTALYFSALRPEDRVAVKPHASPIFHAMQ
YLMGHQTREKMENFRGYGGVQSYPSRTKDIDDVDFSTGSVGLGVGITALASMVQDFITAKDWGGDVTPGRMVALVGDAEL
DEGNIYEVLQEGWKNDLRNTWWIIDYNRQSLDGIVREGLFGRIEKIFEAFGWDVVRVKYGALQRAAFEEPGGEALRDWID
ACPNVEYSALTYMGGANWRKRLMEDLGDQGAVSALIDKRSDAELAALMENLGGNCVETMADTFAAIDHDRPTCFLAYTIK
GWGTPIAGHKDNHGGLMTKAQMAEWQTHMGVAEGEEWELMATVSDTKGFQAYLDQVPFFAKGARRHSDARLSVPAVAVDT
SREISTQMAFGKILDDLARGDSDLAARIMTTSPDVTGTTGLGPWVNRRKLFAREAQKDAFIEHRIPSTAKWNFDPKGQHL
ELGIAEMNLFLLLGAAGLSHSLWGKRVIPIGTVYDPFVHRGLDALNYACYQDARFMIVGTPSGVTLAPEGGAHQSVGTPL
TGMAQDGLASFEPAFADELAVIMEWAFDYMQRDGEGDPDERTWLRDETGGSVYLRLTTKPLEQPGQRVDDAFRQGAIDGA
YWLRKPGPNCSVVIAYQGAVADEAIAAAGLVGEHRRDVAVLAVTSADRLNAGWTAAQRERARGNPQAVSHVERLLGELPA
HCTLITAIDGHPATLSWLGSVAGHRVVSHGVEHFGQTGTIGDLYRHFGLDRHSLARSVGELTTGARRIPGGQAG
>Mature_793_residues
SQNIEHLRTVEQRLLWLSHWMIHNANHLRAKEDGIKIGGHQASSASMVSIMTALYFSALRPEDRVAVKPHASPIFHAMQY
LMGHQTREKMENFRGYGGVQSYPSRTKDIDDVDFSTGSVGLGVGITALASMVQDFITAKDWGGDVTPGRMVALVGDAELD
EGNIYEVLQEGWKNDLRNTWWIIDYNRQSLDGIVREGLFGRIEKIFEAFGWDVVRVKYGALQRAAFEEPGGEALRDWIDA
CPNVEYSALTYMGGANWRKRLMEDLGDQGAVSALIDKRSDAELAALMENLGGNCVETMADTFAAIDHDRPTCFLAYTIKG
WGTPIAGHKDNHGGLMTKAQMAEWQTHMGVAEGEEWELMATVSDTKGFQAYLDQVPFFAKGARRHSDARLSVPAVAVDTS
REISTQMAFGKILDDLARGDSDLAARIMTTSPDVTGTTGLGPWVNRRKLFAREAQKDAFIEHRIPSTAKWNFDPKGQHLE
LGIAEMNLFLLLGAAGLSHSLWGKRVIPIGTVYDPFVHRGLDALNYACYQDARFMIVGTPSGVTLAPEGGAHQSVGTPLT
GMAQDGLASFEPAFADELAVIMEWAFDYMQRDGEGDPDERTWLRDETGGSVYLRLTTKPLEQPGQRVDDAFRQGAIDGAY
WLRKPGPNCSVVIAYQGAVADEAIAAAGLVGEHRRDVAVLAVTSADRLNAGWTAAQRERARGNPQAVSHVERLLGELPAH
CTLITAIDGHPATLSWLGSVAGHRVVSHGVEHFGQTGTIGDLYRHFGLDRHSLARSVGELTTGARRIPGGQAG

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=631, Percent_Identity=25.6735340729002, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 86896; Mature: 86765

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNIEHLRTVEQRLLWLSHWMIHNANHLRAKEDGIKIGGHQASSASMVSIMTALYFSAL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCHHHHHHHHHHHHHHHC
RPEDRVAVKPHASPIFHAMQYLMGHQTREKMENFRGYGGVQSYPSRTKDIDDVDFSTGSV
CCCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GLGVGITALASMVQDFITAKDWGGDVTPGRMVALVGDAELDEGNIYEVLQEGWKNDLRNT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCE
WWIIDYNRQSLDGIVREGLFGRIEKIFEAFGWDVVRVKYGALQRAAFEEPGGEALRDWID
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCHHHHHHHHH
ACPNVEYSALTYMGGANWRKRLMEDLGDQGAVSALIDKRSDAELAALMENLGGNCVETMA
HCCCCCCHHEEECCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHH
DTFAAIDHDRPTCFLAYTIKGWGTPIAGHKDNHGGLMTKAQMAEWQTHMGVAEGEEWELM
HHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCEEEE
ATVSDTKGFQAYLDQVPFFAKGARRHSDARLSVPAVAVDTSREISTQMAFGKILDDLARG
EEECCCCHHHHHHHCCCHHHHHCCCCCCCEEECCEEEECCCHHHHHHHHHHHHHHHHHCC
DSDLAARIMTTSPDVTGTTGLGPWVNRRKLFAREAQKDAFIEHRIPSTAKWNFDPKGQHL
CCHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
ELGIAEMNLFLLLGAAGLSHSLWGKRVIPIGTVYDPFVHRGLDALNYACYQDARFMIVGT
EEEHHHHEEHHHEECCCCCHHHCCCEEEECCCHHHHHHHHCHHHHHHHHHCCCEEEEEEC
PSGVTLAPEGGAHQSVGTPLTGMAQDGLASFEPAFADELAVIMEWAFDYMQRDGEGDPDE
CCCCEECCCCCCCCCCCCCCCCCHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
RTWLRDETGGSVYLRLTTKPLEQPGQRVDDAFRQGAIDGAYWLRKPGPNCSVVIAYQGAV
HCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHEECCCCCCCEEEEEECCCH
ADEAIAAAGLVGEHRRDVAVLAVTSADRLNAGWTAAQRERARGNPQAVSHVERLLGELPA
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCC
HCTLITAIDGHPATLSWLGSVAGHRVVSHGVEHFGQTGTIGDLYRHFGLDRHSLARSVGE
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHH
LTTGARRIPGGQAG
HHCCCCCCCCCCCC
>Mature Secondary Structure 
SQNIEHLRTVEQRLLWLSHWMIHNANHLRAKEDGIKIGGHQASSASMVSIMTALYFSAL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCHHHHHHHHHHHHHHHC
RPEDRVAVKPHASPIFHAMQYLMGHQTREKMENFRGYGGVQSYPSRTKDIDDVDFSTGSV
CCCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
GLGVGITALASMVQDFITAKDWGGDVTPGRMVALVGDAELDEGNIYEVLQEGWKNDLRNT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCE
WWIIDYNRQSLDGIVREGLFGRIEKIFEAFGWDVVRVKYGALQRAAFEEPGGEALRDWID
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCHHHHHHHHH
ACPNVEYSALTYMGGANWRKRLMEDLGDQGAVSALIDKRSDAELAALMENLGGNCVETMA
HCCCCCCHHEEECCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHH
DTFAAIDHDRPTCFLAYTIKGWGTPIAGHKDNHGGLMTKAQMAEWQTHMGVAEGEEWELM
HHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCEEEE
ATVSDTKGFQAYLDQVPFFAKGARRHSDARLSVPAVAVDTSREISTQMAFGKILDDLARG
EEECCCCHHHHHHHCCCHHHHHCCCCCCCEEECCEEEECCCHHHHHHHHHHHHHHHHHCC
DSDLAARIMTTSPDVTGTTGLGPWVNRRKLFAREAQKDAFIEHRIPSTAKWNFDPKGQHL
CCHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
ELGIAEMNLFLLLGAAGLSHSLWGKRVIPIGTVYDPFVHRGLDALNYACYQDARFMIVGT
EEEHHHHEEHHHEECCCCCHHHCCCEEEECCCHHHHHHHHCHHHHHHHHHCCCEEEEEEC
PSGVTLAPEGGAHQSVGTPLTGMAQDGLASFEPAFADELAVIMEWAFDYMQRDGEGDPDE
CCCCEECCCCCCCCCCCCCCCCCHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
RTWLRDETGGSVYLRLTTKPLEQPGQRVDDAFRQGAIDGAYWLRKPGPNCSVVIAYQGAV
HCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHEECCCCCCCEEEEEECCCH
ADEAIAAAGLVGEHRRDVAVLAVTSADRLNAGWTAAQRERARGNPQAVSHVERLLGELPA
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCC
HCTLITAIDGHPATLSWLGSVAGHRVVSHGVEHFGQTGTIGDLYRHFGLDRHSLARSVGE
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHH
LTTGARRIPGGQAG
HHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA