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The map label for this gene is lrp [C]

Identifier: 99082548

GI number: 99082548

Start: 2852734

End: 2853201

Strand: Reverse

Name: lrp [C]

Synonym: TM1040_2708

Alternate gene names: 99082548

Gene position: 2853201-2852734 (Counterclockwise)

Preceding gene: 99082552

Following gene: 99082543

Centisome position: 89.14

GC content: 61.11

Gene sequence:

>468_bases
ATGGACAGATTCGATGCCCTGATACTCGAGGCGATTCAAACCGACGCCCGCATCACCGCCGAGGCGCTCTCGAAACAGGT
GGGACTCTCGCCGGACGCCTGCCGCAAACGTCTCGCTCGTCTGCGCGCTTCTGATGTGGTGGAGAGCGAGATCACCGTGC
TTGCGCCCGAGCAGGTGGGGCGTGGCTTGTTGCTGATCGTGGAGGTCACACTGCAAAACGAGCGGATGGAGGATCTGGAC
CGCTTCAAGGCGCAGATGCGGGCGGCGCCCGAAGTCATGCAATGCTACTATGTGACCGGGAATGCAGACTTTGTGCTGAT
CATCTCGGCGCGCGATATGGCCGACTATGATGACTTCACCCGCCGCCAGTTCTTTGCCGACGAAAACGTGCTGCGGTTTC
GCACCAGCGCGGTGATGGATCGGGTGAAGACGGGGTTTTCCATGCCCGTGCTCGACCGGGCAGACTAG

Upstream 100 bases:

>100_bases
GGGCCGAATTTCGGCCCGTCTGTGCCTGGATGCGTCCAAAAACCGCCCCTGTGCCTGCTGATGGGTGTTGCATGGGCCGA
AATTCCGCCATGCTTGGGTG

Downstream 100 bases:

>100_bases
GCAGATCGGGCCGTGCTGGGCTGATCTGAGTTTCGAAAGCCCGCGCGCGGACAGTTTGTCAGCGCACGGGTCCTGTGGGT
GTGCAGCCTATTCGGCGGCT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MDRFDALILEAIQTDARITAEALSKQVGLSPDACRKRLARLRASDVVESEITVLAPEQVGRGLLLIVEVTLQNERMEDLD
RFKAQMRAAPEVMQCYYVTGNADFVLIISARDMADYDDFTRRQFFADENVLRFRTSAVMDRVKTGFSMPVLDRAD

Sequences:

>Translated_155_residues
MDRFDALILEAIQTDARITAEALSKQVGLSPDACRKRLARLRASDVVESEITVLAPEQVGRGLLLIVEVTLQNERMEDLD
RFKAQMRAAPEVMQCYYVTGNADFVLIISARDMADYDDFTRRQFFADENVLRFRTSAVMDRVKTGFSMPVLDRAD
>Mature_155_residues
MDRFDALILEAIQTDARITAEALSKQVGLSPDACRKRLARLRASDVVESEITVLAPEQVGRGLLLIVEVTLQNERMEDLD
RFKAQMRAAPEVMQCYYVTGNADFVLIISARDMADYDDFTRRQFFADENVLRFRTSAVMDRVKTGFSMPVLDRAD

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=32.1678321678322, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=28, Blast_Score=80, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17598; Mature: 17598

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFDALILEAIQTDARITAEALSKQVGLSPDACRKRLARLRASDVVESEITVLAPEQVG
CCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECHHHHC
RGLLLIVEVTLQNERMEDLDRFKAQMRAAPEVMQCYYVTGNADFVLIISARDMADYDDFT
CCEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHEEEEEECCCCEEEEEECCCCCCCHHHH
RRQFFADENVLRFRTSAVMDRVKTGFSMPVLDRAD
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDRFDALILEAIQTDARITAEALSKQVGLSPDACRKRLARLRASDVVESEITVLAPEQVG
CCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECHHHHC
RGLLLIVEVTLQNERMEDLDRFKAQMRAAPEVMQCYYVTGNADFVLIISARDMADYDDFT
CCEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHEEEEEECCCCEEEEEECCCCCCCHHHH
RRQFFADENVLRFRTSAVMDRVKTGFSMPVLDRAD
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]