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The map label for this gene is ykvY [H]

Identifier: 99082552

GI number: 99082552

Start: 2856397

End: 2857500

Strand: Reverse

Name: ykvY [H]

Synonym: TM1040_2712

Alternate gene names: 99082552

Gene position: 2857500-2856397 (Counterclockwise)

Preceding gene: 99082553

Following gene: 99082548

Centisome position: 89.27

GC content: 63.13

Gene sequence:

>1104_bases
ATGACCGAATTTCCGCTGACCGCCGCCCGCCTTGCCGCTCTGCGCACCCGTATGGAGCTCACAGGCACCGATCTTGTTGC
GCTTGGCCCGTCGAGCCACATGGTTTGGCTGTCCGGCGTGCACCCCCATGGTGACGAGCGCCCGGTGATGCTCTTGGTGA
GCCAGTCCTACGCGGGCTTTCTGATGCCCGCCCTCAATGCCGCGGCTGCCCGCAAGGACACGGACCTGCCGTTCCATCCT
TGGCGCGATGATGAAGGCCCGGATGCGGCCCTCGCCGAACTGCTGAAGGCCTGCGGCGCGACGCGCCCGAACCTCTCCGT
CGTGCTTGATGAAACCATGCGTACCGATTTCTCCCTGCGCTTGCTGGACGCGCTCGAAGCACCGCGCCGTCGCTTTGCGG
ATGACACCGTGAGTCTCCTGCGCGCATCGAAGGACGACAGCGAATATCACGCGATCAAGGCCGCGCATCTGACCAACGAC
AAAGCCGTCAAAGCCGCGTTTGCCGCGCTCAAGGAAGGCGTGACGGAACGCGAGATCGTAGAGCTGATCAAATCCGAATA
TACTGCCGCCGGCGCGACGCTGGAGTTTTGTTCAGTCTGTTTTGGGGCCTCCGGCGCCTTTCCGCATCACACCCCGGGTG
ACACGCCGTTGGCCCGGAATTCTGCGGTGCTGATTGACACCGGCTGCCGTCTCGATGGCTACCCCTCGGATATGACCCGC
TCGGGCTACTTCGGCACCCCCGAAGAAGAATATGAAGAGGTGTTTCAGACCGTCGAGAAAGCGGTTCAGGCCGCACTCGC
GGTGGCCAAGCCCGGCGTTGTGGCCAGCGAGATCGACAAGGCGGCGCGCGACGTGATCGCGGCGGCAGGCTACGGCGATC
GCTTTTTGCATCGCACCGGTCATGGTCTTGGCATCGACATCCATGAGCCGCCCTATATCGCTGCGAACTCCGATGTGGTC
CTGCGCGAAGGCAATGTGTTCTCGATCGAGCCGGGCATCTACCTTGAGGGCAAATTCGGCGTCCGCCTCGAGGAGATCGT
GATCCTGCGCGAAGACGGCGCGGAGATCTTCTCCGAGATGCCGCGCGACATGGTGCGCGTCTAA

Upstream 100 bases:

>100_bases
GTCTGGTTGAAAAACAGTAATCTCCCCGACTGTGGGTCGCTGCATCCGTGGCGGCCCGCTTTTTCTCTCTTCCTCTCCCC
ACTCTTTTCCGGAGGCCTCG

Downstream 100 bases:

>100_bases
ACGCCCTCTCCGGGCCCTCTCCGGGGGACGCATCAGAAGGGCGGCGTGGCTCAGGGCTGCGCCGCCTTTTTGCCAAGCTG
CCCCGGCACTTCGAGATCAT

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTEFPLTAARLAALRTRMELTGTDLVALGPSSHMVWLSGVHPHGDERPVMLLVSQSYAGFLMPALNAAAARKDTDLPFHP
WRDDEGPDAALAELLKACGATRPNLSVVLDETMRTDFSLRLLDALEAPRRRFADDTVSLLRASKDDSEYHAIKAAHLTND
KAVKAAFAALKEGVTEREIVELIKSEYTAAGATLEFCSVCFGASGAFPHHTPGDTPLARNSAVLIDTGCRLDGYPSDMTR
SGYFGTPEEEYEEVFQTVEKAVQAALAVAKPGVVASEIDKAARDVIAAAGYGDRFLHRTGHGLGIDIHEPPYIAANSDVV
LREGNVFSIEPGIYLEGKFGVRLEEIVILREDGAEIFSEMPRDMVRV

Sequences:

>Translated_367_residues
MTEFPLTAARLAALRTRMELTGTDLVALGPSSHMVWLSGVHPHGDERPVMLLVSQSYAGFLMPALNAAAARKDTDLPFHP
WRDDEGPDAALAELLKACGATRPNLSVVLDETMRTDFSLRLLDALEAPRRRFADDTVSLLRASKDDSEYHAIKAAHLTND
KAVKAAFAALKEGVTEREIVELIKSEYTAAGATLEFCSVCFGASGAFPHHTPGDTPLARNSAVLIDTGCRLDGYPSDMTR
SGYFGTPEEEYEEVFQTVEKAVQAALAVAKPGVVASEIDKAARDVIAAAGYGDRFLHRTGHGLGIDIHEPPYIAANSDVV
LREGNVFSIEPGIYLEGKFGVRLEEIVILREDGAEIFSEMPRDMVRV
>Mature_366_residues
TEFPLTAARLAALRTRMELTGTDLVALGPSSHMVWLSGVHPHGDERPVMLLVSQSYAGFLMPALNAAAARKDTDLPFHPW
RDDEGPDAALAELLKACGATRPNLSVVLDETMRTDFSLRLLDALEAPRRRFADDTVSLLRASKDDSEYHAIKAAHLTNDK
AVKAAFAALKEGVTEREIVELIKSEYTAAGATLEFCSVCFGASGAFPHHTPGDTPLARNSAVLIDTGCRLDGYPSDMTRS
GYFGTPEEEYEEVFQTVEKAVQAALAVAKPGVVASEIDKAARDVIAAAGYGDRFLHRTGHGLGIDIHEPPYIAANSDVVL
REGNVFSIEPGIYLEGKFGVRLEEIVILREDGAEIFSEMPRDMVRV

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=232, Percent_Identity=28.448275862069, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI93141226, Length=244, Percent_Identity=27.8688524590164, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI264681565, Length=229, Percent_Identity=27.0742358078603, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788728, Length=243, Percent_Identity=34.9794238683128, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1789275, Length=253, Percent_Identity=23.3201581027668, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786364, Length=168, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17509539, Length=230, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322999, Length=239, Percent_Identity=25.1046025104602, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161078230, Length=237, Percent_Identity=26.1603375527426, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357287, Length=237, Percent_Identity=26.1603375527426, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39824; Mature: 39693

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00491 PROLINE_PEPTIDASE ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFPLTAARLAALRTRMELTGTDLVALGPSSHMVWLSGVHPHGDERPVMLLVSQSYAGF
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCCHH
LMPALNAAAARKDTDLPFHPWRDDEGPDAALAELLKACGATRPNLSVVLDETMRTDFSLR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHCCCHHHH
LLDALEAPRRRFADDTVSLLRASKDDSEYHAIKAAHLTNDKAVKAAFAALKEGVTEREIV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCCCHHHHHHHHHHHHCCCHHHHH
ELIKSEYTAAGATLEFCSVCFGASGAFPHHTPGDTPLARNSAVLIDTGCRLDGYPSDMTR
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
SGYFGTPEEEYEEVFQTVEKAVQAALAVAKPGVVASEIDKAARDVIAAAGYGDRFLHRTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCC
HGLGIDIHEPPYIAANSDVVLREGNVFSIEPGIYLEGKFGVRLEEIVILREDGAEIFSEM
CCCEEECCCCCEEECCCCEEEECCCEEEECCCEEEECCCCCEEEEEEEECCCCHHHHHHC
PRDMVRV
CHHHHCC
>Mature Secondary Structure 
TEFPLTAARLAALRTRMELTGTDLVALGPSSHMVWLSGVHPHGDERPVMLLVSQSYAGF
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCCHH
LMPALNAAAARKDTDLPFHPWRDDEGPDAALAELLKACGATRPNLSVVLDETMRTDFSLR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHCCCHHHH
LLDALEAPRRRFADDTVSLLRASKDDSEYHAIKAAHLTNDKAVKAAFAALKEGVTEREIV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCCCHHHHHHHHHHHHCCCHHHHH
ELIKSEYTAAGATLEFCSVCFGASGAFPHHTPGDTPLARNSAVLIDTGCRLDGYPSDMTR
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCC
SGYFGTPEEEYEEVFQTVEKAVQAALAVAKPGVVASEIDKAARDVIAAAGYGDRFLHRTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCC
HGLGIDIHEPPYIAANSDVVLREGNVFSIEPGIYLEGKFGVRLEEIVILREDGAEIFSEM
CCCEEECCCCCEEECCCCEEEECCCEEEECCCEEEECCCCCEEEEEEEECCCCHHHHHHC
PRDMVRV
CHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]