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The map label for this gene is ygjG [C]

Identifier: 99082531

GI number: 99082531

Start: 2832091

End: 2833464

Strand: Reverse

Name: ygjG [C]

Synonym: TM1040_2691

Alternate gene names: 99082531

Gene position: 2833464-2832091 (Counterclockwise)

Preceding gene: 99082532

Following gene: 99082530

Centisome position: 88.52

GC content: 61.28

Gene sequence:

>1374_bases
ATGCTGAAGAACGATCAACTGGACCAATGGGACCGCGACAACTTCTTTCACCCCTCGACCCATCTGGCGCAGCACGCGCG
CGGCGAGAGTGCAAACCGGGTGATCAAGACTGCCTCCGGCGTCTTTATCGAGGATCGTGACGGCACCAAGCTCTTGGATG
CGTTTGCCGGGCTCTACTGCGTCAACGTCGGCTATGGTCGTCAGGAGATTGCCGAGGCCATCGCCGATCAGGCGCGTGAG
CTGGCCTATTACCATTCCTATGTCGGACATGGCACCGAGGCCTCGATCACGCTGGCCAAGATGATCCTGGATCGCGCGCC
CAAGAACATGTCGAAGGTCTACTTCGGCCTTGGCGGTTCGGACGCCAATGAAACCAATGTCAAACTGATCTGGTATTACA
ACAACATCCTTGGCCGCCCCGAAAAGAAGAAAATCATCTCGCGCTGGCGTGGCTATCACGGCTCCGGGCTGGTCACCGGC
TCGCTGACGGGGCTTGAGCTCTTTCACAAGAAATTCGACCTGCCCGTCGAACAGGTGATCCACACCGAGGCGCCCTATTA
CTTCCGTCGCGAGGATCTGAACCAGACCGAAGAGCAGTTCGTCGCGCATTGCGTGGCCGAGCTGGAAGCGTTGATCGAGC
GTGAAGGTGCCGACACCATCGCCGCCTTCATCGGTGAGCCGATCCTTGGCACCGGGGGCATCGTGCCACCGCCCGCAGGC
TATTGGGAGGCGATCCAGACAGTTCTGAATAAGCACGACATCCTTCTGGTGGCGGATGAAGTGGTCACCGGCTTTGGCCG
TCTCGGCACCATGTTCGGTTCTGACCACTACGGTCTGGAGCCCGACATCATCACCATCGCCAAGGGTCTGACCTCGGCCT
ATGCGCCGCTTTCCGGGTCGATCGTCAGTGACAAGGTCTGGAAGGTGCTTGAGCAGGGCACCGACGAGAACGGTCCCATC
GGCCACGGCTGGACCTATTCCGCCCACCCGATCGGGGCGGCGGCGGGTGTCGCCAACCTCAAGCTCCTCGACGAGCTGAA
CCTCGTGAGCAACGCAGGCGAGGTCGGTGCCTACCTCAACGCCACCATGGCCGAGGCTCTGAGCCAGCACGCCAACGTCG
GCGATGTACGCGGCGAAGGCCTGCTCTGCGCGGTGGAATTTGTGAAGGATCGCGACAGTCGCACCTTCTTTGACGCCGCC
GACAAGATCGGGCCTCAGATCTCTGCGAAACTCCTCGAGCAGGACAAGATCATTGCCCGTGCCATGCCCCAGGGCGACAT
CCTGGGCTTTGCCCCGCCGTTCTGCCTCACCCGTGCCGAGGCCGATCAGGTGGTCGAAGGCACCCTGCGCGCTGTTAAGG
CTGTGCTGGGCTGA

Upstream 100 bases:

>100_bases
CACCGAGGTCAAATACGTCTGCCGCGACTGGGCGTAACCCTTGAATGATACGAGATTTGCCGCCCTCGCGGGTGGAACAC
GGAAATAGGAAGGACCGAAA

Downstream 100 bases:

>100_bases
TCAATCAACCCCGGAATTTTTTCAATCGCTCGCGGGTCTCTCGCGGGCGGTTTTTTTGTTTTCAGAGTCTGATCAACAGT
TTGTTGGGCTCATCCTGTCG

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MLKNDQLDQWDRDNFFHPSTHLAQHARGESANRVIKTASGVFIEDRDGTKLLDAFAGLYCVNVGYGRQEIAEAIADQARE
LAYYHSYVGHGTEASITLAKMILDRAPKNMSKVYFGLGGSDANETNVKLIWYYNNILGRPEKKKIISRWRGYHGSGLVTG
SLTGLELFHKKFDLPVEQVIHTEAPYYFRREDLNQTEEQFVAHCVAELEALIEREGADTIAAFIGEPILGTGGIVPPPAG
YWEAIQTVLNKHDILLVADEVVTGFGRLGTMFGSDHYGLEPDIITIAKGLTSAYAPLSGSIVSDKVWKVLEQGTDENGPI
GHGWTYSAHPIGAAAGVANLKLLDELNLVSNAGEVGAYLNATMAEALSQHANVGDVRGEGLLCAVEFVKDRDSRTFFDAA
DKIGPQISAKLLEQDKIIARAMPQGDILGFAPPFCLTRAEADQVVEGTLRAVKAVLG

Sequences:

>Translated_457_residues
MLKNDQLDQWDRDNFFHPSTHLAQHARGESANRVIKTASGVFIEDRDGTKLLDAFAGLYCVNVGYGRQEIAEAIADQARE
LAYYHSYVGHGTEASITLAKMILDRAPKNMSKVYFGLGGSDANETNVKLIWYYNNILGRPEKKKIISRWRGYHGSGLVTG
SLTGLELFHKKFDLPVEQVIHTEAPYYFRREDLNQTEEQFVAHCVAELEALIEREGADTIAAFIGEPILGTGGIVPPPAG
YWEAIQTVLNKHDILLVADEVVTGFGRLGTMFGSDHYGLEPDIITIAKGLTSAYAPLSGSIVSDKVWKVLEQGTDENGPI
GHGWTYSAHPIGAAAGVANLKLLDELNLVSNAGEVGAYLNATMAEALSQHANVGDVRGEGLLCAVEFVKDRDSRTFFDAA
DKIGPQISAKLLEQDKIIARAMPQGDILGFAPPFCLTRAEADQVVEGTLRAVKAVLG
>Mature_457_residues
MLKNDQLDQWDRDNFFHPSTHLAQHARGESANRVIKTASGVFIEDRDGTKLLDAFAGLYCVNVGYGRQEIAEAIADQARE
LAYYHSYVGHGTEASITLAKMILDRAPKNMSKVYFGLGGSDANETNVKLIWYYNNILGRPEKKKIISRWRGYHGSGLVTG
SLTGLELFHKKFDLPVEQVIHTEAPYYFRREDLNQTEEQFVAHCVAELEALIEREGADTIAAFIGEPILGTGGIVPPPAG
YWEAIQTVLNKHDILLVADEVVTGFGRLGTMFGSDHYGLEPDIITIAKGLTSAYAPLSGSIVSDKVWKVLEQGTDENGPI
GHGWTYSAHPIGAAAGVANLKLLDELNLVSNAGEVGAYLNATMAEALSQHANVGDVRGEGLLCAVEFVKDRDSRTFFDAA
DKIGPQISAKLLEQDKIIARAMPQGDILGFAPPFCLTRAEADQVVEGTLRAVKAVLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=27.1662763466042, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.4881516587678, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI226442705, Length=423, Percent_Identity=27.8959810874704, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226442709, Length=361, Percent_Identity=28.2548476454294, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI24119277, Length=423, Percent_Identity=26.241134751773, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI4557809, Length=427, Percent_Identity=27.1662763466042, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI284507298, Length=236, Percent_Identity=30.9322033898305, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI188536080, Length=388, Percent_Identity=24.2268041237113, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI38679950, Length=388, Percent_Identity=24.2268041237113, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI38679946, Length=388, Percent_Identity=24.2268041237113, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI145693181, Length=413, Percent_Identity=26.8765133171913, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787560, Length=438, Percent_Identity=28.7671232876712, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788044, Length=400, Percent_Identity=26.75, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789016, Length=407, Percent_Identity=26.044226044226, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789759, Length=421, Percent_Identity=25.41567695962, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786991, Length=447, Percent_Identity=24.8322147651007, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786349, Length=310, Percent_Identity=25.1612903225806, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=28.2110091743119, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25144271, Length=420, Percent_Identity=25.7142857142857, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71992977, Length=439, Percent_Identity=25.5125284738041, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144274, Length=234, Percent_Identity=29.9145299145299, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=394, Percent_Identity=24.6192893401015, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323470, Length=437, Percent_Identity=27.0022883295195, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=354, Percent_Identity=25.1412429378531, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324386, Length=369, Percent_Identity=27.10027100271, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=373, Percent_Identity=25.7372654155496, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28574759, Length=445, Percent_Identity=28.5393258426966, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI161085790, Length=442, Percent_Identity=28.2805429864253, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=23.448275862069, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357415, Length=416, Percent_Identity=25.7211538461538, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281366494, Length=283, Percent_Identity=26.8551236749117, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24667139, Length=283, Percent_Identity=26.8551236749117, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24667143, Length=283, Percent_Identity=26.8551236749117, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 49758; Mature: 49758

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNDQLDQWDRDNFFHPSTHLAQHARGESANRVIKTASGVFIEDRDGTKLLDAFAGLYC
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHEE
VNVGYGRQEIAEAIADQARELAYYHSYVGHGTEASITLAKMILDRAPKNMSKVYFGLGGS
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHEEEECCCC
DANETNVKLIWYYNNILGRPEKKKIISRWRGYHGSGLVTGSLTGLELFHKKFDLPVEQVI
CCCCCCEEEEEEECCHHCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCHHHHH
HTEAPYYFRREDLNQTEEQFVAHCVAELEALIEREGADTIAAFIGEPILGTGGIVPPPAG
HCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCH
YWEAIQTVLNKHDILLVADEVVTGFGRLGTMFGSDHYGLEPDIITIAKGLTSAYAPLSGS
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
IVSDKVWKVLEQGTDENGPIGHGWTYSAHPIGAAAGVANLKLLDELNLVSNAGEVGAYLN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ATMAEALSQHANVGDVRGEGLLCAVEFVKDRDSRTFFDAADKIGPQISAKLLEQDKIIAR
HHHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHH
AMPQGDILGFAPPFCLTRAEADQVVEGTLRAVKAVLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLKNDQLDQWDRDNFFHPSTHLAQHARGESANRVIKTASGVFIEDRDGTKLLDAFAGLYC
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHEE
VNVGYGRQEIAEAIADQARELAYYHSYVGHGTEASITLAKMILDRAPKNMSKVYFGLGGS
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHEEEECCCC
DANETNVKLIWYYNNILGRPEKKKIISRWRGYHGSGLVTGSLTGLELFHKKFDLPVEQVI
CCCCCCEEEEEEECCHHCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCHHHHH
HTEAPYYFRREDLNQTEEQFVAHCVAELEALIEREGADTIAAFIGEPILGTGGIVPPPAG
HCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCH
YWEAIQTVLNKHDILLVADEVVTGFGRLGTMFGSDHYGLEPDIITIAKGLTSAYAPLSGS
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
IVSDKVWKVLEQGTDENGPIGHGWTYSAHPIGAAAGVANLKLLDELNLVSNAGEVGAYLN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ATMAEALSQHANVGDVRGEGLLCAVEFVKDRDSRTFFDAADKIGPQISAKLLEQDKIIAR
HHHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHH
AMPQGDILGFAPPFCLTRAEADQVVEGTLRAVKAVLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]