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The map label for this gene is frpC [H]

Identifier: 99082530

GI number: 99082530

Start: 2829620

End: 2831923

Strand: Reverse

Name: frpC [H]

Synonym: TM1040_2690

Alternate gene names: 99082530

Gene position: 2831923-2829620 (Counterclockwise)

Preceding gene: 99082531

Following gene: 99082528

Centisome position: 88.47

GC content: 61.33

Gene sequence:

>2304_bases
ATGCTGCATTCGGCACGGAAGAGGCAACATCGCCCCGGCTGCAGCGTGCTTGCCGTCAAAGCGCTGCCTGTTTCCATAGG
CAAATGGTATGAGTGCAAACACGAGATGACGACTTATGTAGTACACGGGACGAATTACAACGATCCCTCATTTTGGGCCT
CCATCTCTGAAGGCAGCCCCGGCCATACGCTTGATTTCACCGGGTTGCCGCCAAATTATGAAATCAACATCAACGCCGAG
GCCAAAACGATCTCGATCTGGGACGGGACGTCTTGGTATAGTGTCGGCGAAAGCGGCAACACGGGCACCAACGCCACTCT
GGGTAGCCCCACCCTTGTCGATGATTTCACTGTCATTCTGGCGAACAATTCAGACGACTACATCGAAGGCTCTGACAACA
ATGACAGCCTCACGGGCGGTACCGGGAACGATACCCTGTCCGGGGACCAAGGTGATGACACCCTCAGAGGGGGTGACGGG
GATGACTATCTAACCGGTGGTGAAGGCAACGACAATATCGACGGTGGCACCGGCAATGACACCATCCGTGGCGACAATGC
GTGGACGAATACCTCGTCAGGAGCCTCAGGCGCGAGCACAACCCCCACGACGTTGACCGTCACCAACTCGGCGGATGGCC
CGATCGAGCTGTGGTGGATCGACGAGACCGGCACAGCCCAATATTACGCCACCCTTCAGCCCGGGGACACCCGGAACCAG
AGCACCTTTGAGGAGCATAACTGGATTCTGCGCCACCCGGATGGCTGGTATCTGGAGTATATCGAGGGGGCTCCGAACCA
GACTGTCAATTTTGGCTCGGCCGGTTTGAATGATACGGTCTACGCGGGCGCTGGAAATGATCTCATCGATGGGATGTACG
GCGATGACCTTCTCTACGGGGAGGGGAACAATGACACGATCTATGGCGATTACGGCTCCGATACGATTTATGGCGGGGCA
GGTGACGATCTTCTGTACGGGGGGGATGGCGACGATACCCTGGCTGGCGGTACCGGATCCGACACGATGTATGGAGGGGC
CGGAAATGACTCCATGGTGGGGTTCGATGACGCCGATACCTTCATTCTCGAGGATGGTTTTGGCAATGACACCATCGTGG
GCGGCGAAGGCGGCACCGATGACGATTTTGTCGATCTCTCCAACCTGACCAGCGGGGTCACCGTCACCTATACCGGCGAT
GAGGCCGGGACCATCACGGATGGCAGCAACACGGCGGAGTTCTCGGAGATCGAGCGGATTCGACTCACGGATCAGGCGGA
TGTGCTGGATGCAAGCGCCTCTTTGGTGGGGGTCGATGTGGACGCCGGGGCCGGTGCGGACACGCTGACCGGCAGCGCGG
GGGATGACAGTCTGACGGGGGGCACGGGGGACGACCGCTTTGTCATGACCACCTCCGGCGGCACCGACACCGTAGGTGAT
TTTGATCTCGGTGACGCCGACCTAGATGGGTTCTACAACGACCAGATCGATGTCAGCGGCCTGTCCGGGGGCTCCGGGGC
GGGCGGACTGGTGACACGCGCGGATGTGGTGGTGACGGATGATGGTTCCGGCAACGCCCTTTTGACCTTTCCCAATGGCG
AACAGCTGGTCCTGCAAGGGGTCGCACCGGCGCAGATCAGCTCGTATCAGCAGCTCTATGCTGCAGGTATTCCCTGCTTC
ACTCCCGGCATCCGCATCGCAACTGCGCGTGGGGCCGTTCCTGTGGAGCATATCCGCAAGGGTGACCTGCTGCAGACGGC
GGACAATGGGTTTCAACCCGTGATCTGGACCGGGCGGCGGGATCTCAGCGCTGCAGAGCTGCGCGCCCGGCCACATTTGA
CCCCGCTCAGGCTGCGCCCCGGCGGGCCGCTTGCCAACGATCGCCCATTGCTGGTTTCACCGCAGCATCGTTTTATGCTC
GGACGCGCGCGGCTGGGCGATATGGACCATCTGCACGAGGCTTTTGTGCGCACGCGGCTGCTGCAGAGCCTCGCGCCAGA
GGATGTGACCCCCTGCAGGCCCGCAGCCGGGGTCAGCTACATTCACCTGATGACCGAGGCGCATCAGGTGATTTTTGCCG
AAGGTGTTGCCACCGAAACCTTCTGGCCCGGCCCAGAGGCGCTGCGTGGCTTGTCCGAGGGCGACCGGCGCGAGCTGTTT
GATCTCTTTCCCGAGCTGTTCCTTGCCGGCGGCCTCTGCGGCGGCACGGGGCGGCACTTTGTTGCCCGGGCCTATTGCCC
ACTGGCGCGTGTTGATCTCAAACGTCGCGACCTGCGGGCGCTGGGCGCGCGCTCCGCGGCCTGA

Upstream 100 bases:

>100_bases
TCTGATCAACAGTTTGTTGGGCTCATCCTGTCGCGCGCATCAATTCAGATCTGCTTGAAGGGCTCTTAACTATTTTACCC
TAATCTTGGATGTAGCGCGG

Downstream 100 bases:

>100_bases
GGTTTGGTTCTGCGCCCTACTCCGCGGCAAGACGGCGCAGGAAAGCGCAGGTAACATCAATCGCTGCCGCCATGTCCTCG
GCAGAGGTATATTCCTCCGG

Product: hemolysin-type calcium-binding region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 767; Mature: 767

Protein sequence:

>767_residues
MLHSARKRQHRPGCSVLAVKALPVSIGKWYECKHEMTTYVVHGTNYNDPSFWASISEGSPGHTLDFTGLPPNYEININAE
AKTISIWDGTSWYSVGESGNTGTNATLGSPTLVDDFTVILANNSDDYIEGSDNNDSLTGGTGNDTLSGDQGDDTLRGGDG
DDYLTGGEGNDNIDGGTGNDTIRGDNAWTNTSSGASGASTTPTTLTVTNSADGPIELWWIDETGTAQYYATLQPGDTRNQ
STFEEHNWILRHPDGWYLEYIEGAPNQTVNFGSAGLNDTVYAGAGNDLIDGMYGDDLLYGEGNNDTIYGDYGSDTIYGGA
GDDLLYGGDGDDTLAGGTGSDTMYGGAGNDSMVGFDDADTFILEDGFGNDTIVGGEGGTDDDFVDLSNLTSGVTVTYTGD
EAGTITDGSNTAEFSEIERIRLTDQADVLDASASLVGVDVDAGAGADTLTGSAGDDSLTGGTGDDRFVMTTSGGTDTVGD
FDLGDADLDGFYNDQIDVSGLSGGSGAGGLVTRADVVVTDDGSGNALLTFPNGEQLVLQGVAPAQISSYQQLYAAGIPCF
TPGIRIATARGAVPVEHIRKGDLLQTADNGFQPVIWTGRRDLSAAELRARPHLTPLRLRPGGPLANDRPLLVSPQHRFML
GRARLGDMDHLHEAFVRTRLLQSLAPEDVTPCRPAAGVSYIHLMTEAHQVIFAEGVATETFWPGPEALRGLSEGDRRELF
DLFPELFLAGGLCGGTGRHFVARAYCPLARVDLKRRDLRALGARSAA

Sequences:

>Translated_767_residues
MLHSARKRQHRPGCSVLAVKALPVSIGKWYECKHEMTTYVVHGTNYNDPSFWASISEGSPGHTLDFTGLPPNYEININAE
AKTISIWDGTSWYSVGESGNTGTNATLGSPTLVDDFTVILANNSDDYIEGSDNNDSLTGGTGNDTLSGDQGDDTLRGGDG
DDYLTGGEGNDNIDGGTGNDTIRGDNAWTNTSSGASGASTTPTTLTVTNSADGPIELWWIDETGTAQYYATLQPGDTRNQ
STFEEHNWILRHPDGWYLEYIEGAPNQTVNFGSAGLNDTVYAGAGNDLIDGMYGDDLLYGEGNNDTIYGDYGSDTIYGGA
GDDLLYGGDGDDTLAGGTGSDTMYGGAGNDSMVGFDDADTFILEDGFGNDTIVGGEGGTDDDFVDLSNLTSGVTVTYTGD
EAGTITDGSNTAEFSEIERIRLTDQADVLDASASLVGVDVDAGAGADTLTGSAGDDSLTGGTGDDRFVMTTSGGTDTVGD
FDLGDADLDGFYNDQIDVSGLSGGSGAGGLVTRADVVVTDDGSGNALLTFPNGEQLVLQGVAPAQISSYQQLYAAGIPCF
TPGIRIATARGAVPVEHIRKGDLLQTADNGFQPVIWTGRRDLSAAELRARPHLTPLRLRPGGPLANDRPLLVSPQHRFML
GRARLGDMDHLHEAFVRTRLLQSLAPEDVTPCRPAAGVSYIHLMTEAHQVIFAEGVATETFWPGPEALRGLSEGDRRELF
DLFPELFLAGGLCGGTGRHFVARAYCPLARVDLKRRDLRALGARSAA
>Mature_767_residues
MLHSARKRQHRPGCSVLAVKALPVSIGKWYECKHEMTTYVVHGTNYNDPSFWASISEGSPGHTLDFTGLPPNYEININAE
AKTISIWDGTSWYSVGESGNTGTNATLGSPTLVDDFTVILANNSDDYIEGSDNNDSLTGGTGNDTLSGDQGDDTLRGGDG
DDYLTGGEGNDNIDGGTGNDTIRGDNAWTNTSSGASGASTTPTTLTVTNSADGPIELWWIDETGTAQYYATLQPGDTRNQ
STFEEHNWILRHPDGWYLEYIEGAPNQTVNFGSAGLNDTVYAGAGNDLIDGMYGDDLLYGEGNNDTIYGDYGSDTIYGGA
GDDLLYGGDGDDTLAGGTGSDTMYGGAGNDSMVGFDDADTFILEDGFGNDTIVGGEGGTDDDFVDLSNLTSGVTVTYTGD
EAGTITDGSNTAEFSEIERIRLTDQADVLDASASLVGVDVDAGAGADTLTGSAGDDSLTGGTGDDRFVMTTSGGTDTVGD
FDLGDADLDGFYNDQIDVSGLSGGSGAGGLVTRADVVVTDDGSGNALLTFPNGEQLVLQGVAPAQISSYQQLYAAGIPCF
TPGIRIATARGAVPVEHIRKGDLLQTADNGFQPVIWTGRRDLSAAELRARPHLTPLRLRPGGPLANDRPLLVSPQHRFML
GRARLGDMDHLHEAFVRTRLLQSLAPEDVTPCRPAAGVSYIHLMTEAHQVIFAEGVATETFWPGPEALRGLSEGDRRELF
DLFPELFLAGGLCGGTGRHFVARAYCPLARVDLKRRDLRALGARSAA

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 80755; Mature: 80755

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHSARKRQHRPGCSVLAVKALPVSIGKWYECKHEMTTYVVHGTNYNDPSFWASISEGSP
CCCCHHHHHCCCCCCEEEEEEEEECCCCCEECCCCEEEEEEECCCCCCHHHEEEECCCCC
GHTLDFTGLPPNYEININAEAKTISIWDGTSWYSVGESGNTGTNATLGSPTLVDDFTVIL
CCEEEECCCCCCEEEEEECCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCEECCEEEEE
ANNSDDYIEGSDNNDSLTGGTGNDTLSGDQGDDTLRGGDGDDYLTGGEGNDNIDGGTGND
ECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
TIRGDNAWTNTSSGASGASTTPTTLTVTNSADGPIELWWIDETGTAQYYATLQPGDTRNQ
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEECCCCCCCC
STFEEHNWILRHPDGWYLEYIEGAPNQTVNFGSAGLNDTVYAGAGNDLIDGMYGDDLLYG
CCHHHCCCEEECCCCCEEEEECCCCCCEEECCCCCCCCEEEECCCCHHHCCCCCCEEEEE
EGNNDTIYGDYGSDTIYGGAGDDLLYGGDGDDTLAGGTGSDTMYGGAGNDSMVGFDDADT
CCCCCEEEECCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCEECCCCCCCEEECCCCCE
FILEDGFGNDTIVGGEGGTDDDFVDLSNLTSGVTVTYTGDEAGTITDGSNTAEFSEIERI
EEEECCCCCCEEECCCCCCCCCEEEHHHCCCCEEEEEECCCCCEEECCCCCCHHHHHHEE
RLTDQADVLDASASLVGVDVDAGAGADTLTGSAGDDSLTGGTGDDRFVMTTSGGTDTVGD
EECCCCHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
FDLGDADLDGFYNDQIDVSGLSGGSGAGGLVTRADVVVTDDGSGNALLTFPNGEQLVLQG
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEEECCCCCEEEECCCCCEEEEEC
VAPAQISSYQQLYAAGIPCFTPGIRIATARGAVPVEHIRKGDLLQTADNGFQPVIWTGRR
CCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHCCCCEEECCCCCCCEEEEECCC
DLSAAELRARPHLTPLRLRPGGPLANDRPLLVSPQHRFMLGRARLGDMDHLHEAFVRTRL
CCCHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCHHEEEECCCCCCHHHHHHHHHHHHH
LQSLAPEDVTPCRPAAGVSYIHLMTEAHQVIFAEGVATETFWPGPEALRGLSEGDRRELF
HHHHCCCCCCCCCCCCCCEEEEEEHHCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHH
DLFPELFLAGGLCGGTGRHFVARAYCPLARVDLKRRDLRALGARSAA
HHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLHSARKRQHRPGCSVLAVKALPVSIGKWYECKHEMTTYVVHGTNYNDPSFWASISEGSP
CCCCHHHHHCCCCCCEEEEEEEEECCCCCEECCCCEEEEEEECCCCCCHHHEEEECCCCC
GHTLDFTGLPPNYEININAEAKTISIWDGTSWYSVGESGNTGTNATLGSPTLVDDFTVIL
CCEEEECCCCCCEEEEEECCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCEECCEEEEE
ANNSDDYIEGSDNNDSLTGGTGNDTLSGDQGDDTLRGGDGDDYLTGGEGNDNIDGGTGND
ECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
TIRGDNAWTNTSSGASGASTTPTTLTVTNSADGPIELWWIDETGTAQYYATLQPGDTRNQ
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEECCCCCCCC
STFEEHNWILRHPDGWYLEYIEGAPNQTVNFGSAGLNDTVYAGAGNDLIDGMYGDDLLYG
CCHHHCCCEEECCCCCEEEEECCCCCCEEECCCCCCCCEEEECCCCHHHCCCCCCEEEEE
EGNNDTIYGDYGSDTIYGGAGDDLLYGGDGDDTLAGGTGSDTMYGGAGNDSMVGFDDADT
CCCCCEEEECCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCEECCCCCCCEEECCCCCE
FILEDGFGNDTIVGGEGGTDDDFVDLSNLTSGVTVTYTGDEAGTITDGSNTAEFSEIERI
EEEECCCCCCEEECCCCCCCCCEEEHHHCCCCEEEEEECCCCCEEECCCCCCHHHHHHEE
RLTDQADVLDASASLVGVDVDAGAGADTLTGSAGDDSLTGGTGDDRFVMTTSGGTDTVGD
EECCCCHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
FDLGDADLDGFYNDQIDVSGLSGGSGAGGLVTRADVVVTDDGSGNALLTFPNGEQLVLQG
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEEECCCCCEEEECCCCCEEEEEC
VAPAQISSYQQLYAAGIPCFTPGIRIATARGAVPVEHIRKGDLLQTADNGFQPVIWTGRR
CCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHCCCCEEECCCCCCCEEEEECCC
DLSAAELRARPHLTPLRLRPGGPLANDRPLLVSPQHRFMLGRARLGDMDHLHEAFVRTRL
CCCHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCHHEEEECCCCCCHHHHHHHHHHHHH
LQSLAPEDVTPCRPAAGVSYIHLMTEAHQVIFAEGVATETFWPGPEALRGLSEGDRRELF
HHHHCCCCCCCCCCCCCCEEEEEEHHCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHH
DLFPELFLAGGLCGGTGRHFVARAYCPLARVDLKRRDLRALGARSAA
HHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]