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The map label for this gene is pcs [H]

Identifier: 99082222

GI number: 99082222

Start: 2502569

End: 2503261

Strand: Direct

Name: pcs [H]

Synonym: TM1040_2382

Alternate gene names: 99082222

Gene position: 2502569-2503261 (Clockwise)

Preceding gene: 99082221

Following gene: 99082223

Centisome position: 78.18

GC content: 56.85

Gene sequence:

>693_bases
ATGACGATTGAACTCCGTGCCCTCTCCGTCCACTTGCTCACCGCCACCGGTGCTGTCTTTGCCATGTTGGCAATGCTAGC
GGCAGTCGATGCCGAGTGGGATCTGATGTATCTCTGGCTCGTGGTGGCCTTTGCGGTGGATGGCGTGGATGGCCCTCTTG
CGCGGCACTTCGATGTCAAACAGAACGCGCCACAGTTTGATGGCGTGCTATTGGATTTGATCATCGACTATCTGACCTAT
GTGTTCATTCCGGCCTTTGCATTGTTCAAATCGGACCTGATGTCCGGCTGGACTGGCTGGGCGGCAATCATCGTCATCAC
TTTTACCAGCGCCATGTATTTCGCAGACACGCGGATGAAGACCAAGGACAACTCCTTTTCCGGGTTTCCCGGCTGCTGGA
ACATGCTTGTGCTGGTGATTTTTGCGCTGGAGCCAAACCACTGGGTCAGCCTTGGTCTGGTGCTGGTCTTGTCGGCAACT
CAGTTCTTGCCGCTGAAGTTCATCCACCCGGTACGTACAGAGCGCTGGCGCAGTGTCTCCCTGCCCGTTGCGCTGGTCTG
GACGGCCCTGGCGGGCTGGACCGCTTGGGTGGAATTTGCGCCCGGACAGCTTGTTCACTGGGCGCTACTGGTGACATCCG
TATACTTGCTGTTTGTGGGTATTGCCCAGCAAATCATGCCCAGTCGCGACTGA

Upstream 100 bases:

>100_bases
ACGTTTCAAGCGTGCAACGGGGAAGTTCCCATCGGAAAACACCGTTAAACGGCAGCGCTTCTGGGTTGCGGCCTGCCTCG
AAATTCGTCATCACGGGCAG

Downstream 100 bases:

>100_bases
TTCTACGGTCAGGCCTCCTCAGCGCTGGAGCCCCCGACGCCTCCGGATTGCCCTCGGAGGCGTGTTGATCGTGCGTTTTT
ACTTATATTTTCCGGTCCAA

Product: CDP-diacylglycerol-choline O-phosphatidyltransferase

Products: NA

Alternate protein names: PC synthase; CDP-diglyceride-choline O-phosphatidyltransferase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTIELRALSVHLLTATGAVFAMLAMLAAVDAEWDLMYLWLVVAFAVDGVDGPLARHFDVKQNAPQFDGVLLDLIIDYLTY
VFIPAFALFKSDLMSGWTGWAAIIVITFTSAMYFADTRMKTKDNSFSGFPGCWNMLVLVIFALEPNHWVSLGLVLVLSAT
QFLPLKFIHPVRTERWRSVSLPVALVWTALAGWTAWVEFAPGQLVHWALLVTSVYLLFVGIAQQIMPSRD

Sequences:

>Translated_230_residues
MTIELRALSVHLLTATGAVFAMLAMLAAVDAEWDLMYLWLVVAFAVDGVDGPLARHFDVKQNAPQFDGVLLDLIIDYLTY
VFIPAFALFKSDLMSGWTGWAAIIVITFTSAMYFADTRMKTKDNSFSGFPGCWNMLVLVIFALEPNHWVSLGLVLVLSAT
QFLPLKFIHPVRTERWRSVSLPVALVWTALAGWTAWVEFAPGQLVHWALLVTSVYLLFVGIAQQIMPSRD
>Mature_229_residues
TIELRALSVHLLTATGAVFAMLAMLAAVDAEWDLMYLWLVVAFAVDGVDGPLARHFDVKQNAPQFDGVLLDLIIDYLTYV
FIPAFALFKSDLMSGWTGWAAIIVITFTSAMYFADTRMKTKDNSFSGFPGCWNMLVLVIFALEPNHWVSLGLVLVLSATQ
FLPLKFIHPVRTERWRSVSLPVALVWTALAGWTAWVEFAPGQLVHWALLVTSVYLLFVGIAQQIMPSRD

Specific function: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP [H]

COG id: COG1183

COG function: function code I; Phosphatidylserine synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.24 [H]

Molecular weight: Translated: 25686; Mature: 25554

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIELRALSVHLLTATGAVFAMLAMLAAVDAEWDLMYLWLVVAFAVDGVDGPLARHFDVK
CEEEEEEHEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCC
QNAPQFDGVLLDLIIDYLTYVFIPAFALFKSDLMSGWTGWAAIIVITFTSAMYFADTRMK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
TKDNSFSGFPGCWNMLVLVIFALEPNHWVSLGLVLVLSATQFLPLKFIHPVRTERWRSVS
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHCHHHHHHHCCCC
LPVALVWTALAGWTAWVEFAPGQLVHWALLVTSVYLLFVGIAQQIMPSRD
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIELRALSVHLLTATGAVFAMLAMLAAVDAEWDLMYLWLVVAFAVDGVDGPLARHFDVK
EEEEEEHEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCC
QNAPQFDGVLLDLIIDYLTYVFIPAFALFKSDLMSGWTGWAAIIVITFTSAMYFADTRMK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
TKDNSFSGFPGCWNMLVLVIFALEPNHWVSLGLVLVLSATQFLPLKFIHPVRTERWRSVS
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHCHHHHHHHCCCC
LPVALVWTALAGWTAWVEFAPGQLVHWALLVTSVYLLFVGIAQQIMPSRD
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]