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The map label for this gene is xerC [H]

Identifier: 99082221

GI number: 99082221

Start: 2501509

End: 2502444

Strand: Direct

Name: xerC [H]

Synonym: TM1040_2381

Alternate gene names: 99082221

Gene position: 2501509-2502444 (Clockwise)

Preceding gene: 99082220

Following gene: 99082222

Centisome position: 78.15

GC content: 65.38

Gene sequence:

>936_bases
TTGAGCGCGGGCGACCCGACGCTGATCTCTCCGGCGGCGCGCGATGCGTTGCAGCGCTGGCTGGACGGTCTCGGTGCGCT
TGAAGGCGCGGCGGACAATACGCTCGCGGCCTATCGCGGCGATGTCGTGGAGTTCCTGTCGTTCATGAGCCTTCACTTTG
GCGCCCCACAGGGACTTGGCGCCCTGCGCCAGATCACCACCGCGGACATGCGCGCCTGGATGGCCTCGGCGCGGTCGTCG
GGCACGGGCGCGCGCTCTCTCGCACGCAAACTCTCCGCTGTGAAAAAATTCTACGGCTGGCTGGCCAAGCGCGAAGGGTT
CGAACCCACGGCCGTTTTGTCGACCCGCGCGCCCAAGTTCCAAAAGAAATTGCCCCGCCCGCTTGATCAGGACGCTGCGC
GAGCAATGATCGACACGGTCGAGTTGCAATCACAGAAGGACTGGGTGTCGGCGCGAGATGTCGCGGTTGTAACACTCCTC
TATGGATGTGGCCTGCGCATCTCCGAGGCACTCGGCCTTCTTGGCAAAGACGCTCCCCTGCCAGCCACACTTCGGATAAA
AGGCAAGGGCGGCAAAGAGCGGGTGGTGCCGGTCCTGCCTGCGGCGCAACAGGCGGTAGAGCGCTACTTGGCCCTCTGCC
CCCACCCCAAAGAAGCCCATCTGCCCTTGTTTCGCGGCGTCCGTGGCGGCGCGCTGCATGCCCGCATGATCCAGGGCGTA
ATGGCAGGCGCGCGTCGGCAGCTGGGTCTTCCCGCAACAGCAACCCCGCATGCCCTGCGCCACAGCTTTGCAACGCATCT
CCTTGAGGCTGGGGGCGACTTGCGCGCCATTCAAGAGCTTCTGGGTCACGCGTCCCTGTCGACCACGCAGGCCTACACCG
CGGTGGATACGGCGCATCTCATGGAAGTCTACGCCCGCGCCCACCCGAAGGCCTGA

Upstream 100 bases:

>100_bases
TTGGCGCCGAGGATCCCCATCAATTCACACCGCAACACGGCACCGACCTTTTGACATTTTTTGGTGGTGTATTCGAGCGC
TGCATGCGCCGTTGGCTGTC

Downstream 100 bases:

>100_bases
GCCCGTAGATCGCGAGGAACCGGCACGTTTCAAGCGTGCAACGGGGAAGTTCCCATCGGAAAACACCGTTAAACGGCAGC
GCTTCTGGGTTGCGGCCTGC

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSAGDPTLISPAARDALQRWLDGLGALEGAADNTLAAYRGDVVEFLSFMSLHFGAPQGLGALRQITTADMRAWMASARSS
GTGARSLARKLSAVKKFYGWLAKREGFEPTAVLSTRAPKFQKKLPRPLDQDAARAMIDTVELQSQKDWVSARDVAVVTLL
YGCGLRISEALGLLGKDAPLPATLRIKGKGGKERVVPVLPAAQQAVERYLALCPHPKEAHLPLFRGVRGGALHARMIQGV
MAGARRQLGLPATATPHALRHSFATHLLEAGGDLRAIQELLGHASLSTTQAYTAVDTAHLMEVYARAHPKA

Sequences:

>Translated_311_residues
MSAGDPTLISPAARDALQRWLDGLGALEGAADNTLAAYRGDVVEFLSFMSLHFGAPQGLGALRQITTADMRAWMASARSS
GTGARSLARKLSAVKKFYGWLAKREGFEPTAVLSTRAPKFQKKLPRPLDQDAARAMIDTVELQSQKDWVSARDVAVVTLL
YGCGLRISEALGLLGKDAPLPATLRIKGKGGKERVVPVLPAAQQAVERYLALCPHPKEAHLPLFRGVRGGALHARMIQGV
MAGARRQLGLPATATPHALRHSFATHLLEAGGDLRAIQELLGHASLSTTQAYTAVDTAHLMEVYARAHPKA
>Mature_310_residues
SAGDPTLISPAARDALQRWLDGLGALEGAADNTLAAYRGDVVEFLSFMSLHFGAPQGLGALRQITTADMRAWMASARSSG
TGARSLARKLSAVKKFYGWLAKREGFEPTAVLSTRAPKFQKKLPRPLDQDAARAMIDTVELQSQKDWVSARDVAVVTLLY
GCGLRISEALGLLGKDAPLPATLRIKGKGGKERVVPVLPAAQQAVERYLALCPHPKEAHLPLFRGVRGGALHARMIQGVM
AGARRQLGLPATATPHALRHSFATHLLEAGGDLRAIQELLGHASLSTTQAYTAVDTAHLMEVYARAHPKA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=262, Percent_Identity=38.1679389312977, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1789261, Length=316, Percent_Identity=33.8607594936709, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790768, Length=162, Percent_Identity=32.0987654320988, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33289; Mature: 33158

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGDPTLISPAARDALQRWLDGLGALEGAADNTLAAYRGDVVEFLSFMSLHFGAPQGLG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
ALRQITTADMRAWMASARSSGTGARSLARKLSAVKKFYGWLAKREGFEPTAVLSTRAPKF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHH
QKKLPRPLDQDAARAMIDTVELQSQKDWVSARDVAVVTLLYGCGLRISEALGLLGKDAPL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
PATLRIKGKGGKERVVPVLPAAQQAVERYLALCPHPKEAHLPLFRGVRGGALHARMIQGV
CEEEEEECCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHH
MAGARRQLGLPATATPHALRHSFATHLLEAGGDLRAIQELLGHASLSTTQAYTAVDTAHL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
MEVYARAHPKA
HHHHHHHCCCC
>Mature Secondary Structure 
SAGDPTLISPAARDALQRWLDGLGALEGAADNTLAAYRGDVVEFLSFMSLHFGAPQGLG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
ALRQITTADMRAWMASARSSGTGARSLARKLSAVKKFYGWLAKREGFEPTAVLSTRAPKF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHH
QKKLPRPLDQDAARAMIDTVELQSQKDWVSARDVAVVTLLYGCGLRISEALGLLGKDAPL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
PATLRIKGKGGKERVVPVLPAAQQAVERYLALCPHPKEAHLPLFRGVRGGALHARMIQGV
CEEEEEECCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHH
MAGARRQLGLPATATPHALRHSFATHLLEAGGDLRAIQELLGHASLSTTQAYTAVDTAHL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
MEVYARAHPKA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]