Click here to switch to the map view.

The map label for this gene is ctaE [H]

Identifier: 99082172

GI number: 99082172

Start: 2452530

End: 2453345

Strand: Reverse

Name: ctaE [H]

Synonym: TM1040_2332

Alternate gene names: 99082172

Gene position: 2453345-2452530 (Counterclockwise)

Preceding gene: 99082173

Following gene: 99082171

Centisome position: 76.64

GC content: 58.46

Gene sequence:

>816_bases
ATGGCGCATGCAAAAAACCACGATTTCCACATTCTGCCGCCTTCTATTTGGCCGCTTCTGAGCTCGCTTGGCGCCTTCGT
CATGCTGTTTGGCGCGGTGCTCTGGATGCACGACTACACCGCCTGGCTGTTCTGGGCCGGTTTGGTTGCGGTGCTCTACT
CTGCCTTCTGCTGGTGGTCTGAGACCATTGCGGAAAACAAGGCAGGCGATCACACGCCGGTTGTTCTGATCGGCCTGCGC
TACGGCTTCATCCTGTTTGTGATGTCCGAAGTCATGTTCTTCTTCGCGTGGTTCTGGTCGTTCTTCAAACACGCCATGTA
CCCGATGGAAGAATACGTCGGCACCGAATATGTCGCGCCCGACATCTACCCGGTTGACGCCTTCCACCTGCCGCTCATCA
ACACGCTGGTGTTGCTGCTCTCTGGCTGTGCTGTGACCTGGGCGCACCACGCGCTTGTGCACGACAATGACCGCAAGGGT
CTGGTGAACGGCCTCGCCATCGGTATCGCACTTGGCATCTTCTTCACTGCGCTGCAGGCCTATGAATATGTGCACCTGCT
GCACGAAGGCTGGGAGTTTGGCGGCGACGAGTTCTACTCCAACTTCTTCATGGCCACCGGTTTCCACGGCTTCCACGTGA
TCCTCGGCACCATCTTCCTGATCGTGTGTCTGATTCGCGCGATGCGGGGCGATTTCACGCCGAAGTCCCACGCGGGCTTT
GAGATGGCGGCCTGGTACTGGCACTTCGTTGACGTTGTGTGGCTGTTCCTCTTCGTGGCCGTCTACATCTGGGGCACCGC
CGGTCTGGCGCACTGA

Upstream 100 bases:

>100_bases
GAGATTGATCTGCCCGAGGGCTATGCCGCTCTCGACACCGGGGATACATCCGGGGCAGAGACAGAACTGAACTAAGGCCG
CTTTGGTGAGGGACACTTAA

Downstream 100 bases:

>100_bases
TCTCAATGTAGCGGGTACATGATTGCGGTTTTCCTTTCGGCAATCAGCACGTATCTAACGGGGCGCGCGGGGATCACCTC
GCGCGCCTCTTGCCTGTTTT

Product: cytochrome c oxidase, subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAHAKNHDFHILPPSIWPLLSSLGAFVMLFGAVLWMHDYTAWLFWAGLVAVLYSAFCWWSETIAENKAGDHTPVVLIGLR
YGFILFVMSEVMFFFAWFWSFFKHAMYPMEEYVGTEYVAPDIYPVDAFHLPLINTLVLLLSGCAVTWAHHALVHDNDRKG
LVNGLAIGIALGIFFTALQAYEYVHLLHEGWEFGGDEFYSNFFMATGFHGFHVILGTIFLIVCLIRAMRGDFTPKSHAGF
EMAAWYWHFVDVVWLFLFVAVYIWGTAGLAH

Sequences:

>Translated_271_residues
MAHAKNHDFHILPPSIWPLLSSLGAFVMLFGAVLWMHDYTAWLFWAGLVAVLYSAFCWWSETIAENKAGDHTPVVLIGLR
YGFILFVMSEVMFFFAWFWSFFKHAMYPMEEYVGTEYVAPDIYPVDAFHLPLINTLVLLLSGCAVTWAHHALVHDNDRKG
LVNGLAIGIALGIFFTALQAYEYVHLLHEGWEFGGDEFYSNFFMATGFHGFHVILGTIFLIVCLIRAMRGDFTPKSHAGF
EMAAWYWHFVDVVWLFLFVAVYIWGTAGLAH
>Mature_270_residues
AHAKNHDFHILPPSIWPLLSSLGAFVMLFGAVLWMHDYTAWLFWAGLVAVLYSAFCWWSETIAENKAGDHTPVVLIGLRY
GFILFVMSEVMFFFAWFWSFFKHAMYPMEEYVGTEYVAPDIYPVDAFHLPLINTLVLLLSGCAVTWAHHALVHDNDRKGL
VNGLAIGIALGIFFTALQAYEYVHLLHEGWEFGGDEFYSNFFMATGFHGFHVILGTIFLIVCLIRAMRGDFTPKSHAGFE
MAAWYWHFVDVVWLFLFVAVYIWGTAGLAH

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=263, Percent_Identity=44.4866920152091, Blast_Score=206, Evalue=2e-53,
Organism=Escherichia coli, GI1786633, Length=188, Percent_Identity=28.7234042553192, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6226542, Length=264, Percent_Identity=34.8484848484849, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 30965; Mature: 30834

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AHAKNHDFHILPPSIWPLLSSLGAFVMLFGAVLWMHDYTAWLFWAGLVAVLYSAFCWWS
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETIAENKAGDHTPVVLIGLRYGFILFVMSEVMFFFAWFWSFFKHAMYPMEEYVGTEYVAP
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
DIYPVDAFHLPLINTLVLLLSGCAVTWAHHALVHDNDRKGLVNGLAIGIALGIFFTALQA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
YEYVHLLHEGWEFGGDEFYSNFFMATGFHGFHVILGTIFLIVCLIRAMRGDFTPKSHAGF
HHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
EMAAWYWHFVDVVWLFLFVAVYIWGTAGLAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]