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The map label for this gene is ctaG

Identifier: 99082173

GI number: 99082173

Start: 2453371

End: 2453958

Strand: Reverse

Name: ctaG

Synonym: TM1040_2333

Alternate gene names: 99082173

Gene position: 2453958-2453371 (Counterclockwise)

Preceding gene: 99082174

Following gene: 99082172

Centisome position: 76.66

GC content: 56.97

Gene sequence:

>588_bases
ATGGCGTTGAACGGACCTCAAAAAACAGTGGTGCAGCTGGTTGGCGTGGTTGTTCTGATGGGTGGCCTCGCCTGGGCGTC
GGTGCCGTTCTATGACTGGTTCTGCCGGGTCACGGGCTTTGGCGGCGTTACGCAGGTCGCCGAGACCGGCTCCGATCAGG
TGCTCGACCAAACCATCAAGGTTCGTTTTGACGCCTCCAAGGACCGCGGCATGCCGTGGGAGTTCAAACCCGTCGAGCGC
ATCATGGAGCTGAAGATTGGCGAGACCGGTCTTGCTTTCTATGAGGCTTACAACCCGACAGACCGTCCGGTTGCAGGCCA
GGCGTCTTACAACGTCGCGCCGTTCTCGGCGGGCTATTACTTTGATAAAATTCAGTGTTTCTGCTTTAACGAGCAGGTGC
TGCAACCGGGGGAGCGGGTGATGATGCCCGTGACCTTCTTCGTGGACCCCGAGATTATCGAGGACCCGGAGGCAAAATAT
GTGCATACGATCACCTTGTCGTATACATTTCATGAGATTGATCTGCCCGAGGGCTATGCCGCTCTCGACACCGGGGATAC
ATCCGGGGCAGAGACAGAACTGAACTAA

Upstream 100 bases:

>100_bases
TTGCTAGGGGGATTCGTCGTGCTGGTTCTGGCGCTGACGATGGTCAAAGTGACCTCCACCGGCTTCAGCTTCCCCGAAAC
CCAGGGCACGGAGTAATCTG

Downstream 100 bases:

>100_bases
GGCCGCTTTGGTGAGGGACACTTAAATGGCGCATGCAAAAAACCACGATTTCCACATTCTGCCGCCTTCTATTTGGCCGC
TTCTGAGCTCGCTTGGCGCC

Product: cytochrome C oxidase assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MALNGPQKTVVQLVGVVVLMGGLAWASVPFYDWFCRVTGFGGVTQVAETGSDQVLDQTIKVRFDASKDRGMPWEFKPVER
IMELKIGETGLAFYEAYNPTDRPVAGQASYNVAPFSAGYYFDKIQCFCFNEQVLQPGERVMMPVTFFVDPEIIEDPEAKY
VHTITLSYTFHEIDLPEGYAALDTGDTSGAETELN

Sequences:

>Translated_195_residues
MALNGPQKTVVQLVGVVVLMGGLAWASVPFYDWFCRVTGFGGVTQVAETGSDQVLDQTIKVRFDASKDRGMPWEFKPVER
IMELKIGETGLAFYEAYNPTDRPVAGQASYNVAPFSAGYYFDKIQCFCFNEQVLQPGERVMMPVTFFVDPEIIEDPEAKY
VHTITLSYTFHEIDLPEGYAALDTGDTSGAETELN
>Mature_194_residues
ALNGPQKTVVQLVGVVVLMGGLAWASVPFYDWFCRVTGFGGVTQVAETGSDQVLDQTIKVRFDASKDRGMPWEFKPVERI
MELKIGETGLAFYEAYNPTDRPVAGQASYNVAPFSAGYYFDKIQCFCFNEQVLQPGERVMMPVTFFVDPEIIEDPEAKYV
HTITLSYTFHEIDLPEGYAALDTGDTSGAETELN

Specific function: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I

COG id: COG3175

COG function: function code O; Cytochrome oxidase assembly factor

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX11/CtaG family

Homologues:

Organism=Homo sapiens, GI4758034, Length=172, Percent_Identity=47.6744186046512, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI242247057, Length=132, Percent_Identity=40.9090909090909, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI242247061, Length=125, Percent_Identity=42.4, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71990692, Length=176, Percent_Identity=44.8863636363636, Blast_Score=169, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6325125, Length=187, Percent_Identity=40.6417112299465, Blast_Score=143, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24581944, Length=160, Percent_Identity=49.375, Blast_Score=162, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXZ_SILST (Q1GE51)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_614327.1
- ProteinModelPortal:   Q1GE51
- SMR:   Q1GE51
- STRING:   Q1GE51
- GeneID:   4078323
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_2333
- NMPDR:   fig|292414.1.peg.694
- eggNOG:   COG3175
- HOGENOM:   HBG525908
- OMA:   PVERIME
- PhylomeDB:   Q1GE51
- ProtClustDB:   PRK05089
- BioCyc:   SSP292414:TM1040_2333-MONOMER
- HAMAP:   MF_00155
- InterPro:   IPR007533
- Gene3D:   G3DSA:2.60.370.10
- PANTHER:   PTHR21320
- PIRSF:   PIRSF005413

Pfam domain/function: PF04442 CtaG_Cox11; SSF110111 CtaG_Cox11

EC number: NA

Molecular weight: Translated: 21678; Mature: 21547

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x111d5adc)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNGPQKTVVQLVGVVVLMGGLAWASVPFYDWFCRVTGFGGVTQVAETGSDQVLDQTIK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCHHHHHHCCCHHHHCCEEE
VRFDASKDRGMPWEFKPVERIMELKIGETGLAFYEAYNPTDRPVAGQASYNVAPFSAGYY
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCE
FDKIQCFCFNEQVLQPGERVMMPVTFFVDPEIIEDPEAKYVHTITLSYTFHEIDLPEGYA
EEEEEEEEECHHHHCCCCEEEEEEEEEECCHHHCCCCCCEEEEEEEEEEEEEEECCCCCE
ALDTGDTSGAETELN
EEECCCCCCCCCCCH
>Mature Secondary Structure 
ALNGPQKTVVQLVGVVVLMGGLAWASVPFYDWFCRVTGFGGVTQVAETGSDQVLDQTIK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCHHHHHHCCCHHHHCCEEE
VRFDASKDRGMPWEFKPVERIMELKIGETGLAFYEAYNPTDRPVAGQASYNVAPFSAGYY
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCE
FDKIQCFCFNEQVLQPGERVMMPVTFFVDPEIIEDPEAKYVHTITLSYTFHEIDLPEGYA
EEEEEEEEECHHHHCCCCEEEEEEEEEECCHHHCCCCCCEEEEEEEEEEEEEEECCCCCE
ALDTGDTSGAETELN
EEECCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA