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The map label for this gene is mrp [H]

Identifier: 99081862

GI number: 99081862

Start: 2126599

End: 2127684

Strand: Reverse

Name: mrp [H]

Synonym: TM1040_2022

Alternate gene names: 99081862

Gene position: 2127684-2126599 (Counterclockwise)

Preceding gene: 99081864

Following gene: 99081861

Centisome position: 66.47

GC content: 66.67

Gene sequence:

>1086_bases
ATGCCCGTCACACAGGAAGAGATTCGCGCCGCTTTGGACCGTCTGGAGCTTCCGGGTGGGGGCACATTGGTGTCACGCGA
CATGCTGCGCGCCCTCTCCATCGAGGGCAGCACAGTGAGATTCGTGATCGAGGCGGCCTCACCGGAAGAGGCCTCCAAGA
TGGAGATGCTGCGCCGGGCGGCAGAGGCTTCGGTCAAGGCGCTGCCCGGTGTCGAGACGGTCGCGGTGGTGCTTACGGCG
CATGGTCCCGCTGCGCCGACCAAATCGGCGCAAAAACCTGCGCCGAGCCTCAAGCTGGGTGGCCATCCTAAACCGCAGGC
TGCGCCGATGAAACCCTCGGGCGTGAAACGCATCCTCGCGGTGGGATCGGGCAAGGGTGGCGTTGGCAAATCCACCGTGA
GCGCCAACCTCGCGGTGGCGCTGGCCCGGCAGGGGCGCAAGGTCGGGCTCTTGGACGCTGACATCTACGGCCCCTCGCAG
CCACGCATGATGGGGGTCTCCGGTCGCCCCGCCAGCCCCGATGGCACCACCATCGAGCCGCTCCATGCCCATGGGGTCAC
GGTGATGTCGATCGGCCTCATGGTGGAGGAGCGCAAGGCCGTGGTCTGGCGCGGCCCGATGCTTATGGGCGCACTCCAGC
AGATGCTGGGGCAGGTGAACTGGGGCGAGCTTGACGTGTTGATCGTCGACCTGCCGCCGGGCACAGGCGATGTGCAACTC
ACGCTCTGCACCAAGGCCGAGCTGTCGGGGGCCATCGTGGTCTCCACCCCGCAGGATGTGGCCCTTCTGGATGCGCGCAA
GGCGCTTGATATGTTCGACACGCTCAAAACCCCGGTGCTGGGCCTCATAGAGAACATGTCCTTCTTTACCTGCCCCGATT
GCGGCGGCACCCATCACATCTTTGGCAACGGCGGTGTTGCCGCAGAAGCCAAGGACCTGGGCCTGCCGCTCCTCGGGGCC
CTGCCGATTGATCTGGAGACCCGGCTGGCGGGCGACAGCGGCACGCCCATCGCAGCCGGAGAGGGCGTCATGGCCGAGGC
CTACGCGCGTATCGCCAAGGGGCTGGTCGAAGGCGGCATGGCGTGA

Upstream 100 bases:

>100_bases
GCCGGGGTGCCGCTCTGGGCAATTTGATGCTTGGGCCGGGAGCGTCGCGTGTCTATATCAGCTCTGGCCCCCGAATACGG
CAGAAACAGGAGTTGCCCGC

Downstream 100 bases:

>100_bases
ATGGTCAGGAGAGACGCGGATGGTGTTTTCAATGGTCTGGGCATGGTGGAGGCAGCAAGCCAAAGGTACGCCCACAATAG
GTTCTGTGAACGCCCGCAGG

Product: putative Mrp (multidrug resistance-associated proteins) family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MPVTQEEIRAALDRLELPGGGTLVSRDMLRALSIEGSTVRFVIEAASPEEASKMEMLRRAAEASVKALPGVETVAVVLTA
HGPAAPTKSAQKPAPSLKLGGHPKPQAAPMKPSGVKRILAVGSGKGGVGKSTVSANLAVALARQGRKVGLLDADIYGPSQ
PRMMGVSGRPASPDGTTIEPLHAHGVTVMSIGLMVEERKAVVWRGPMLMGALQQMLGQVNWGELDVLIVDLPPGTGDVQL
TLCTKAELSGAIVVSTPQDVALLDARKALDMFDTLKTPVLGLIENMSFFTCPDCGGTHHIFGNGGVAAEAKDLGLPLLGA
LPIDLETRLAGDSGTPIAAGEGVMAEAYARIAKGLVEGGMA

Sequences:

>Translated_361_residues
MPVTQEEIRAALDRLELPGGGTLVSRDMLRALSIEGSTVRFVIEAASPEEASKMEMLRRAAEASVKALPGVETVAVVLTA
HGPAAPTKSAQKPAPSLKLGGHPKPQAAPMKPSGVKRILAVGSGKGGVGKSTVSANLAVALARQGRKVGLLDADIYGPSQ
PRMMGVSGRPASPDGTTIEPLHAHGVTVMSIGLMVEERKAVVWRGPMLMGALQQMLGQVNWGELDVLIVDLPPGTGDVQL
TLCTKAELSGAIVVSTPQDVALLDARKALDMFDTLKTPVLGLIENMSFFTCPDCGGTHHIFGNGGVAAEAKDLGLPLLGA
LPIDLETRLAGDSGTPIAAGEGVMAEAYARIAKGLVEGGMA
>Mature_360_residues
PVTQEEIRAALDRLELPGGGTLVSRDMLRALSIEGSTVRFVIEAASPEEASKMEMLRRAAEASVKALPGVETVAVVLTAH
GPAAPTKSAQKPAPSLKLGGHPKPQAAPMKPSGVKRILAVGSGKGGVGKSTVSANLAVALARQGRKVGLLDADIYGPSQP
RMMGVSGRPASPDGTTIEPLHAHGVTVMSIGLMVEERKAVVWRGPMLMGALQQMLGQVNWGELDVLIVDLPPGTGDVQLT
LCTKAELSGAIVVSTPQDVALLDARKALDMFDTLKTPVLGLIENMSFFTCPDCGGTHHIFGNGGVAAEAKDLGLPLLGAL
PIDLETRLAGDSGTPIAAGEGVMAEAYARIAKGLVEGGMA

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=252, Percent_Identity=49.6031746031746, Blast_Score=244, Evalue=8e-65,
Organism=Homo sapiens, GI118572611, Length=218, Percent_Identity=43.5779816513761, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI6912540, Length=225, Percent_Identity=42.6666666666667, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI87082045, Length=243, Percent_Identity=50.6172839506173, Blast_Score=237, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI25143050, Length=256, Percent_Identity=41.015625, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322188, Length=221, Percent_Identity=39.8190045248869, Blast_Score=171, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321347, Length=220, Percent_Identity=40.9090909090909, Blast_Score=160, Evalue=4e-40,
Organism=Drosophila melanogaster, GI221511043, Length=242, Percent_Identity=38.4297520661157, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24667611, Length=217, Percent_Identity=44.7004608294931, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI19921440, Length=254, Percent_Identity=41.3385826771654, Blast_Score=171, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 37203; Mature: 37072

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTQEEIRAALDRLELPGGGTLVSRDMLRALSIEGSTVRFVIEAASPEEASKMEMLRRA
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHH
AEASVKALPGVETVAVVLTAHGPAAPTKSAQKPAPSLKLGGHPKPQAAPMKPSGVKRILA
HHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEE
VGSGKGGVGKSTVSANLAVALARQGRKVGLLDADIYGPSQPRMMGVSGRPASPDGTTIEP
ECCCCCCCCCCHHHHHHHEEEHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCEECC
LHAHGVTVMSIGLMVEERKAVVWRGPMLMGALQQMLGQVNWGELDVLIVDLPPGTGDVQL
HHHCCEEEEEEEEEEECCCEEEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEE
TLCTKAELSGAIVVSTPQDVALLDARKALDMFDTLKTPVLGLIENMSFFTCPDCGGTHHI
EEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEE
FGNGGVAAEAKDLGLPLLGALPIDLETRLAGDSGTPIAAGEGVMAEAYARIAKGLVEGGM
ECCCCCEECHHHCCCCEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
A
C
>Mature Secondary Structure 
PVTQEEIRAALDRLELPGGGTLVSRDMLRALSIEGSTVRFVIEAASPEEASKMEMLRRA
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHH
AEASVKALPGVETVAVVLTAHGPAAPTKSAQKPAPSLKLGGHPKPQAAPMKPSGVKRILA
HHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEE
VGSGKGGVGKSTVSANLAVALARQGRKVGLLDADIYGPSQPRMMGVSGRPASPDGTTIEP
ECCCCCCCCCCHHHHHHHEEEHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCEECC
LHAHGVTVMSIGLMVEERKAVVWRGPMLMGALQQMLGQVNWGELDVLIVDLPPGTGDVQL
HHHCCEEEEEEEEEEECCCEEEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEE
TLCTKAELSGAIVVSTPQDVALLDARKALDMFDTLKTPVLGLIENMSFFTCPDCGGTHHI
EEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEE
FGNGGVAAEAKDLGLPLLGALPIDLETRLAGDSGTPIAAGEGVMAEAYARIAKGLVEGGM
ECCCCCEECHHHCCCCEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]