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The map label for this gene is qor [H]

Identifier: 99081751

GI number: 99081751

Start: 2012602

End: 2013576

Strand: Direct

Name: qor [H]

Synonym: TM1040_1910

Alternate gene names: 99081751

Gene position: 2012602-2013576 (Clockwise)

Preceding gene: 99081746

Following gene: 99081753

Centisome position: 62.88

GC content: 62.15

Gene sequence:

>975_bases
ATGCTATCCTTTCGTATAGTAAAACATGGAACAAATGGGACTCTTTGCGACACGCCTTTCGCGCCCCCCGGACCAGGTCA
AATCGAAATTGAAATACATGCCTGCGCTTTGAACTTTGCCGATTTGCTGATGATCAAGGGGAATTACCAGGATACGCCGT
CCCTTCCGTTTACCCCGGGGCTGGAATGCGCAGGACGGATCACCGCTGTTGGCCCGCAAATTTCGAATTTCCGAATTGGC
GACCGTGTTGCGGTTTTTGGCGGACAAGGCGGATTGGCCGAAATCGGCGTTTTTGATGCCGCTCGTGCGGTGCCGATCCC
GGACACTGTCAGTTACGAGGATGCAGCGGCCGCGTTGATTGCGCATGGCACCAGCCTTCTGGCGCTGGAGCATCTGGCCC
GGCTCCAGCCCGGCGAGCGCCTGCTTGTCACCGGAGCCGCCGGTGGCGTGGGCCTGACCGCAGTCGAAATCGGCAAGCTC
ATGGGCGCAGAGGTGATCGCGCAGGCGCGTGGGGCAGAAAAGCTCGCGGTGGCCAAGGCAGCCGGAGCGGATCACCTGAT
TGACGCCTCAGACGACCTGCGCCAGCGCGTCAAGGATCTGGGCGGTGCGGATGTGGTCTATGATGCGGTGGGAGGCGACA
CGTGGGAGGCTGCCTTTCGCGCCACCAATCCGGGGGGGCGTTTGTTGCCGATCGGCTTTGCCGGTGGAGCGGTGCCGCAA
ATCCCCGCCAACCACCTGCTCGTCAAAAACCTCACTGTGTTCGGCTTTTATATCGGTGGCTTGATCAAACTGCGCCCTGA
GCTGGGGCAGCAGACGTTCGAGACCCTGATGCGCTGGCTGGCGGAGGGGCGGATCACGCCTCACATCAGCCACCGCCTCC
CCCTGAGCGAGACGGACGCCGGGCTCGAGCTGATCCGCAGCCGCGCCGCCACCGGCAAGGTGATCATACAACCCCAAGCT
GGACGGGTGCGCTGA

Upstream 100 bases:

>100_bases
TTTGCAGCCACTCACCATAAATGGTGAGGCATGAAATCGGTATTGAACCACCCGTACATGATTCGAATCATACAGGCCAC
AGACTGAGAGAATAACCATA

Downstream 100 bases:

>100_bases
CCATTTCTGTGCCCACGGCGCGCAACCCCGGCTGAGACAGCCCGGCAAAACCCTGACGGATCAGGCTTGCGAGGTGGTCG
ACATATTGCGCCCTTGACCG

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLSFRIVKHGTNGTLCDTPFAPPGPGQIEIEIHACALNFADLLMIKGNYQDTPSLPFTPGLECAGRITAVGPQISNFRIG
DRVAVFGGQGGLAEIGVFDAARAVPIPDTVSYEDAAAALIAHGTSLLALEHLARLQPGERLLVTGAAGGVGLTAVEIGKL
MGAEVIAQARGAEKLAVAKAAGADHLIDASDDLRQRVKDLGGADVVYDAVGGDTWEAAFRATNPGGRLLPIGFAGGAVPQ
IPANHLLVKNLTVFGFYIGGLIKLRPELGQQTFETLMRWLAEGRITPHISHRLPLSETDAGLELIRSRAATGKVIIQPQA
GRVR

Sequences:

>Translated_324_residues
MLSFRIVKHGTNGTLCDTPFAPPGPGQIEIEIHACALNFADLLMIKGNYQDTPSLPFTPGLECAGRITAVGPQISNFRIG
DRVAVFGGQGGLAEIGVFDAARAVPIPDTVSYEDAAAALIAHGTSLLALEHLARLQPGERLLVTGAAGGVGLTAVEIGKL
MGAEVIAQARGAEKLAVAKAAGADHLIDASDDLRQRVKDLGGADVVYDAVGGDTWEAAFRATNPGGRLLPIGFAGGAVPQ
IPANHLLVKNLTVFGFYIGGLIKLRPELGQQTFETLMRWLAEGRITPHISHRLPLSETDAGLELIRSRAATGKVIIQPQA
GRVR
>Mature_324_residues
MLSFRIVKHGTNGTLCDTPFAPPGPGQIEIEIHACALNFADLLMIKGNYQDTPSLPFTPGLECAGRITAVGPQISNFRIG
DRVAVFGGQGGLAEIGVFDAARAVPIPDTVSYEDAAAALIAHGTSLLALEHLARLQPGERLLVTGAAGGVGLTAVEIGKL
MGAEVIAQARGAEKLAVAKAAGADHLIDASDDLRQRVKDLGGADVVYDAVGGDTWEAAFRATNPGGRLLPIGFAGGAVPQ
IPANHLLVKNLTVFGFYIGGLIKLRPELGQQTFETLMRWLAEGRITPHISHRLPLSETDAGLELIRSRAATGKVIIQPQA
GRVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=30.8681672025724, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI24308257, Length=315, Percent_Identity=27.9365079365079, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI194239674, Length=307, Percent_Identity=28.6644951140065, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI13236495, Length=307, Percent_Identity=28.6644951140065, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI28557745, Length=259, Percent_Identity=30.8880308880309, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=26.5671641791045, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=26.5671641791045, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI194239676, Length=296, Percent_Identity=28.7162162162162, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI67078404, Length=286, Percent_Identity=24.4755244755245, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI67078406, Length=280, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI47519420, Length=219, Percent_Identity=26.9406392694064, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=321, Percent_Identity=32.398753894081, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789651, Length=303, Percent_Identity=25.7425742574257, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=291, Percent_Identity=27.1477663230241, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17507255, Length=298, Percent_Identity=26.8456375838926, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17556000, Length=277, Percent_Identity=24.9097472924188, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=311, Percent_Identity=28.9389067524116, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323961, Length=298, Percent_Identity=24.8322147651007, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=303, Percent_Identity=23.7623762376238, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=285, Percent_Identity=23.5087719298246, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323729, Length=286, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550423, Length=330, Percent_Identity=22.1212121212121, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33936; Mature: 33936

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFRIVKHGTNGTLCDTPFAPPGPGQIEIEIHACALNFADLLMIKGNYQDTPSLPFTPG
CCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEEECCCCCCCCCCCCCC
LECAGRITAVGPQISNFRIGDRVAVFGGQGGLAEIGVFDAARAVPIPDTVSYEDAAAALI
CCCCCEEEEECCCCCCEEECCEEEEEECCCCEEEEEHHCCCCCCCCCCCCCHHHHHHHHH
AHGTSLLALEHLARLQPGERLLVTGAAGGVGLTAVEIGKLMGAEVIAQARGAEKLAVAKA
HCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
AGADHLIDASDDLRQRVKDLGGADVVYDAVGGDTWEAAFRATNPGGRLLPIGFAGGAVPQ
CCCCCEECCCHHHHHHHHHCCCCCEEEECCCCCCCHHEEEECCCCCEEEEEECCCCCCCC
IPANHLLVKNLTVFGFYIGGLIKLRPELGQQTFETLMRWLAEGRITPHISHRLPLSETDA
CCCCCEEEHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
GLELIRSRAATGKVIIQPQAGRVR
HHHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure
MLSFRIVKHGTNGTLCDTPFAPPGPGQIEIEIHACALNFADLLMIKGNYQDTPSLPFTPG
CCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEEECCCCCCCCCCCCCC
LECAGRITAVGPQISNFRIGDRVAVFGGQGGLAEIGVFDAARAVPIPDTVSYEDAAAALI
CCCCCEEEEECCCCCCEEECCEEEEEECCCCEEEEEHHCCCCCCCCCCCCCHHHHHHHHH
AHGTSLLALEHLARLQPGERLLVTGAAGGVGLTAVEIGKLMGAEVIAQARGAEKLAVAKA
HCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
AGADHLIDASDDLRQRVKDLGGADVVYDAVGGDTWEAAFRATNPGGRLLPIGFAGGAVPQ
CCCCCEECCCHHHHHHHHHCCCCCEEEECCCCCCCHHEEEECCCCCEEEEEECCCCCCCC
IPANHLLVKNLTVFGFYIGGLIKLRPELGQQTFETLMRWLAEGRITPHISHRLPLSETDA
CCCCCEEEHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
GLELIRSRAATGKVIIQPQAGRVR
HHHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]