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The map label for this gene is cutL [H]

Identifier: 99081606

GI number: 99081606

Start: 1855343

End: 1857721

Strand: Reverse

Name: cutL [H]

Synonym: TM1040_1765

Alternate gene names: 99081606

Gene position: 1857721-1855343 (Counterclockwise)

Preceding gene: 99081607

Following gene: 99081605

Centisome position: 58.04

GC content: 60.87

Gene sequence:

>2379_bases
ATGCCTAAGGATATTGAAGCCAAGGAAAGCGGCATAGGGGCCGCCACCAAACGGCGCGAAGACGTAAGGTTCCTGACGGG
AACCGGGAATTATGCTGACGACATCAATGTAAACGGTCAGGCCTATGTGCATTTCCTGCGCTCGGATGTGGCGCATGGGC
GGATCACCTCGCTTGAGACTGCCGCAGCGGCGGCGATGCCGGGCGTGCTGCGGGTGTTCACCGGGGCAGATTTCGAAGGC
GTCGGAGGACTGCCCTGCGGCTGGCAGGTGACGGATCGCTTTGGTGAGGTGATGCAGGAACCTGCCCACCCGGTGCTGGC
GCAGGGCAAGGTGCGCCATGTGGGTGATCCGATCGCCGCGGTGGTGGCCGAGAGCGCCGAATTGGCTCGCGATGCCGCCG
AGGCGATCGAACTGGAGATCGAAGAGCTTCCGGCAGTGATCGACATGAAGGCCGCTCTTGCTGAGGAGGCCCCGAAGGTA
CATGACGATCTGACGTCAAACCTCTGTTATGATTGGGGCTTTGTCGAAGAGAACAAGGATGCGGTGGCCAAGGCCTTTGA
TGAGGCCGCCCATGTAACCACGCTCGAGTTGGTCAACAATCGTTTGGTCGCCAACCCGATGGAGCCGCGCGTGGCGGTGG
GCGATTTCAACCGCGCTACCGGCGAAAGCACGCTTTATACTACAAGCCAGAACCCGCATGTGATCCGGCTCCTGATGGGC
GCCTTTGTGCTCGGCATTCCGGAGCATAAATTGCGCGTGGTGGCCCCGGATGTGGGGGGCGGTTTTGGCTCCAAGATCTT
CCACTACGCCGAAGAAGCGTTTTGCACCTTTGCCGCCAAGGCGCTCAACCGCGCGGTGAAATGGACCTCCTCGCGGTCCG
AGGCCTTCATGTCTGATGCCCATGGCCGCGATCATGTGACCAAGATCGAACTGGCGCTGGACGCAGACAACAACTTCACC
GCTCTGCGCACCGAAACTTACGCCAATATGGGGGCGTATCTCTCGACCTTCGCGCCCTCGGTGCCGACCTGGCTGCATGG
CACGCTGATGGCGGGCAACTACAAGACGCCGCTCATTTATGTGAACGTCAAGGCGGTCTTTACCAATACGGTGCCAGTCG
ATGCCTATCGCGGCGCTGGGCGTCCCGAGGCGACCTTCCAGTTGGAGCGCGTCATCGACAAGGCCGCGCGCGAGCTGGAT
GTCGACCCGGTCGCGCTCCGGCGGCAGAACTTTGTCACCGAGTTCCCCTATGCCACGCCTGTGGCGGTGGAATATGACAC
CGGCGACTATGTGGCGACGATGGATAAGCTTGAAGAGATTGCGGATATCGCAGGCTTTGCCGCGCGCCGCGCCGAGAGCG
AGAAAAGCGGCAAACTGCGTGGTCTGGGTGTCAACTGCTATATCGAAGCCTGTGGTATCGCGCCCTCGAACCTCGTGGGT
CAACTTGGTGCGCGCGCAGGGCTCTATGAGAGTGCGACGGTACGCGTCAATGCAACTGGCGGTATCGTGGTGATGACCGG
CAGTCACAGCCATGGGCAAGGGCATGAGACGTCCTTTCCGCAGGTGATCGCCGAGATGATCGGCATCCCCGAGGATATGG
TGGAGATCGAGCACGGCGACACCAACAACGCGCCGATGGGCATGGGCACCTATGGCTCGCGTTCCTTGGCGGTGGGCGGC
TCTGCCATGGTGCGCGCGACCGAAAAGATCATCAGCAAGGCCAAGAAGATCGCGGCGCATCTGATGGAGGCTTCGGACGC
CGATATTGAGCTTAAGGACGGGAGGTTCTCGGTGGCAGGCACGGATAAATCCGTGGCCTGGGGCGATGTGACCTTGGCGG
CTTATGTGCCACATAACTACCCGCTCGAAGAGATCGAACCGGGGCTGGAGGAGACGGCGTTCTATGATCCGGCGAACTTT
ACCTACCCGGCTGGCGCTTATGCCTGTGAGGTCGAAGTGGATCCCGAGACTGGCAAAGTCACCATCGAGCGCTTTGCCGC
TGCCGATGACTTTGGCAATATCGTTAACCCGATGATTGTGGACGGTCAGGTCCACGGCGGAATTGGACAGGGCATTGGGC
AGGCGCTTCTGGAGGGCTGTGTTTATGACGAGGATGGTCAGCTCTTGTCCGCGAGCTTCATGGATTACGCCATGCCGCGC
GCGGATGATGTGCCGTTTTATCAGGTGGATCATTCCTGCCAGACCCCCTGCACGCATAACCCTCTTGGGGTGAAAGGCTG
CGGAGAGGCAGGGGCAATTGGATCTCCGCCAGCGGTGGTCAATGCGGTGGTGGATGCGCTGCGCTCTGCCGGGAAGGATG
TCACCCACATCGACATGCCGCTGACGCCGGCGCGGGTCTGGGCGGCGATGCAAGGTTGA

Upstream 100 bases:

>100_bases
ATCCAGCGGATCAGTTCTGGTCTGGCTGCGGCGGGAAGAGGAGCCCGACGCGCCGCATGACCAGAAAGCCCGGTTCGCAA
TTCTGGGAGGAGTGTGGATT

Downstream 100 bases:

>100_bases
GATGGCGGAGCGGGGGCCAGCCCCCGCACCCCCGGGATATTTATGAGAAGATGAAGGAGCCCAAGGGCGATCCTTCGGAA
AGGAAGAGCGATGTATGAGT

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 792; Mature: 791

Protein sequence:

>792_residues
MPKDIEAKESGIGAATKRREDVRFLTGTGNYADDINVNGQAYVHFLRSDVAHGRITSLETAAAAAMPGVLRVFTGADFEG
VGGLPCGWQVTDRFGEVMQEPAHPVLAQGKVRHVGDPIAAVVAESAELARDAAEAIELEIEELPAVIDMKAALAEEAPKV
HDDLTSNLCYDWGFVEENKDAVAKAFDEAAHVTTLELVNNRLVANPMEPRVAVGDFNRATGESTLYTTSQNPHVIRLLMG
AFVLGIPEHKLRVVAPDVGGGFGSKIFHYAEEAFCTFAAKALNRAVKWTSSRSEAFMSDAHGRDHVTKIELALDADNNFT
ALRTETYANMGAYLSTFAPSVPTWLHGTLMAGNYKTPLIYVNVKAVFTNTVPVDAYRGAGRPEATFQLERVIDKAARELD
VDPVALRRQNFVTEFPYATPVAVEYDTGDYVATMDKLEEIADIAGFAARRAESEKSGKLRGLGVNCYIEACGIAPSNLVG
QLGARAGLYESATVRVNATGGIVVMTGSHSHGQGHETSFPQVIAEMIGIPEDMVEIEHGDTNNAPMGMGTYGSRSLAVGG
SAMVRATEKIISKAKKIAAHLMEASDADIELKDGRFSVAGTDKSVAWGDVTLAAYVPHNYPLEEIEPGLEETAFYDPANF
TYPAGAYACEVEVDPETGKVTIERFAAADDFGNIVNPMIVDGQVHGGIGQGIGQALLEGCVYDEDGQLLSASFMDYAMPR
ADDVPFYQVDHSCQTPCTHNPLGVKGCGEAGAIGSPPAVVNAVVDALRSAGKDVTHIDMPLTPARVWAAMQG

Sequences:

>Translated_792_residues
MPKDIEAKESGIGAATKRREDVRFLTGTGNYADDINVNGQAYVHFLRSDVAHGRITSLETAAAAAMPGVLRVFTGADFEG
VGGLPCGWQVTDRFGEVMQEPAHPVLAQGKVRHVGDPIAAVVAESAELARDAAEAIELEIEELPAVIDMKAALAEEAPKV
HDDLTSNLCYDWGFVEENKDAVAKAFDEAAHVTTLELVNNRLVANPMEPRVAVGDFNRATGESTLYTTSQNPHVIRLLMG
AFVLGIPEHKLRVVAPDVGGGFGSKIFHYAEEAFCTFAAKALNRAVKWTSSRSEAFMSDAHGRDHVTKIELALDADNNFT
ALRTETYANMGAYLSTFAPSVPTWLHGTLMAGNYKTPLIYVNVKAVFTNTVPVDAYRGAGRPEATFQLERVIDKAARELD
VDPVALRRQNFVTEFPYATPVAVEYDTGDYVATMDKLEEIADIAGFAARRAESEKSGKLRGLGVNCYIEACGIAPSNLVG
QLGARAGLYESATVRVNATGGIVVMTGSHSHGQGHETSFPQVIAEMIGIPEDMVEIEHGDTNNAPMGMGTYGSRSLAVGG
SAMVRATEKIISKAKKIAAHLMEASDADIELKDGRFSVAGTDKSVAWGDVTLAAYVPHNYPLEEIEPGLEETAFYDPANF
TYPAGAYACEVEVDPETGKVTIERFAAADDFGNIVNPMIVDGQVHGGIGQGIGQALLEGCVYDEDGQLLSASFMDYAMPR
ADDVPFYQVDHSCQTPCTHNPLGVKGCGEAGAIGSPPAVVNAVVDALRSAGKDVTHIDMPLTPARVWAAMQG
>Mature_791_residues
PKDIEAKESGIGAATKRREDVRFLTGTGNYADDINVNGQAYVHFLRSDVAHGRITSLETAAAAAMPGVLRVFTGADFEGV
GGLPCGWQVTDRFGEVMQEPAHPVLAQGKVRHVGDPIAAVVAESAELARDAAEAIELEIEELPAVIDMKAALAEEAPKVH
DDLTSNLCYDWGFVEENKDAVAKAFDEAAHVTTLELVNNRLVANPMEPRVAVGDFNRATGESTLYTTSQNPHVIRLLMGA
FVLGIPEHKLRVVAPDVGGGFGSKIFHYAEEAFCTFAAKALNRAVKWTSSRSEAFMSDAHGRDHVTKIELALDADNNFTA
LRTETYANMGAYLSTFAPSVPTWLHGTLMAGNYKTPLIYVNVKAVFTNTVPVDAYRGAGRPEATFQLERVIDKAARELDV
DPVALRRQNFVTEFPYATPVAVEYDTGDYVATMDKLEEIADIAGFAARRAESEKSGKLRGLGVNCYIEACGIAPSNLVGQ
LGARAGLYESATVRVNATGGIVVMTGSHSHGQGHETSFPQVIAEMIGIPEDMVEIEHGDTNNAPMGMGTYGSRSLAVGGS
AMVRATEKIISKAKKIAAHLMEASDADIELKDGRFSVAGTDKSVAWGDVTLAAYVPHNYPLEEIEPGLEETAFYDPANFT
YPAGAYACEVEVDPETGKVTIERFAAADDFGNIVNPMIVDGQVHGGIGQGIGQALLEGCVYDEDGQLLSASFMDYAMPRA
DDVPFYQVDHSCQTPCTHNPLGVKGCGEAGAIGSPPAVVNAVVDALRSAGKDVTHIDMPLTPARVWAAMQG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=797, Percent_Identity=25.0941028858218, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI91823271, Length=804, Percent_Identity=24.0049751243781, Blast_Score=144, Evalue=4e-34,
Organism=Escherichia coli, GI1789230, Length=796, Percent_Identity=29.1457286432161, Blast_Score=249, Evalue=5e-67,
Organism=Escherichia coli, GI1789246, Length=811, Percent_Identity=25.6473489519112, Blast_Score=205, Evalue=1e-53,
Organism=Escherichia coli, GI1786478, Length=758, Percent_Identity=26.7810026385224, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17540638, Length=814, Percent_Identity=23.5872235872236, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17539860, Length=765, Percent_Identity=25.2287581699346, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32566215, Length=540, Percent_Identity=25.1851851851852, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17737937, Length=804, Percent_Identity=24.7512437810945, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24647193, Length=801, Percent_Identity=23.9700374531835, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24647201, Length=796, Percent_Identity=22.7386934673367, Blast_Score=104, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84634; Mature: 84503

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKDIEAKESGIGAATKRREDVRFLTGTGNYADDINVNGQAYVHFLRSDVAHGRITSLET
CCCCCCCHHCCCCCHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
AAAAAMPGVLRVFTGADFEGVGGLPCGWQVTDRFGEVMQEPAHPVLAQGKVRHVGDPIAA
HHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHCCCHHHCCCHHHH
VVAESAELARDAAEAIELEIEELPAVIDMKAALAEEAPKVHDDLTSNLCYDWGFVEENKD
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCEECCCCCCCCHH
AVAKAFDEAAHVTTLELVNNRLVANPMEPRVAVGDFNRATGESTLYTTSQNPHVIRLLMG
HHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEECCCCCCCCCCEEEECCCCCHHHHHHHH
AFVLGIPEHKLRVVAPDVGGGFGSKIFHYAEEAFCTFAAKALNRAVKWTSSRSEAFMSDA
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
HGRDHVTKIELALDADNNFTALRTETYANMGAYLSTFAPSVPTWLHGTLMAGNYKTPLIY
CCCCCEEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHCCEEEECCCCCCEEE
VNVKAVFTNTVPVDAYRGAGRPEATFQLERVIDKAARELDVDPVALRRQNFVTEFPYATP
EEEEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHCCCCCCC
VAVEYDTGDYVATMDKLEEIADIAGFAARRAESEKSGKLRGLGVNCYIEACGIAPSNLVG
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCHHHHHH
QLGARAGLYESATVRVNATGGIVVMTGSHSHGQGHETSFPQVIAEMIGIPEDMVEIEHGD
HHHCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHEEEECCC
TNNAPMGMGTYGSRSLAVGGSAMVRATEKIISKAKKIAAHLMEASDADIELKDGRFSVAG
CCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEC
TDKSVAWGDVTLAAYVPHNYPLEEIEPGLEETAFYDPANFTYPAGAYACEVEVDPETGKV
CCCCEEECCEEEEEECCCCCCHHHHCCCHHHHCEECCCCCCCCCCCEEEEEEECCCCCCE
TIERFAAADDFGNIVNPMIVDGQVHGGIGQGIGQALLEGCVYDEDGQLLSASFMDYAMPR
EEEHHHHHHHHHHCCCCEEECCEECCCHHHHHHHHHHHCCEECCCCCEEHHHHHHHHCCC
ADDVPFYQVDHSCQTPCTHNPLGVKGCGEAGAIGSPPAVVNAVVDALRSAGKDVTHIDMP
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCC
LTPARVWAAMQG
CCHHHHHHCCCC
>Mature Secondary Structure 
PKDIEAKESGIGAATKRREDVRFLTGTGNYADDINVNGQAYVHFLRSDVAHGRITSLET
CCCCCCHHCCCCCHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
AAAAAMPGVLRVFTGADFEGVGGLPCGWQVTDRFGEVMQEPAHPVLAQGKVRHVGDPIAA
HHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHCCCHHHCCCHHHH
VVAESAELARDAAEAIELEIEELPAVIDMKAALAEEAPKVHDDLTSNLCYDWGFVEENKD
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCEECCCCCCCCHH
AVAKAFDEAAHVTTLELVNNRLVANPMEPRVAVGDFNRATGESTLYTTSQNPHVIRLLMG
HHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEECCCCCCCCCCEEEECCCCCHHHHHHHH
AFVLGIPEHKLRVVAPDVGGGFGSKIFHYAEEAFCTFAAKALNRAVKWTSSRSEAFMSDA
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
HGRDHVTKIELALDADNNFTALRTETYANMGAYLSTFAPSVPTWLHGTLMAGNYKTPLIY
CCCCCEEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHCCEEEECCCCCCEEE
VNVKAVFTNTVPVDAYRGAGRPEATFQLERVIDKAARELDVDPVALRRQNFVTEFPYATP
EEEEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHCCCCCCC
VAVEYDTGDYVATMDKLEEIADIAGFAARRAESEKSGKLRGLGVNCYIEACGIAPSNLVG
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCHHHHHH
QLGARAGLYESATVRVNATGGIVVMTGSHSHGQGHETSFPQVIAEMIGIPEDMVEIEHGD
HHHCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHEEEECCC
TNNAPMGMGTYGSRSLAVGGSAMVRATEKIISKAKKIAAHLMEASDADIELKDGRFSVAG
CCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEC
TDKSVAWGDVTLAAYVPHNYPLEEIEPGLEETAFYDPANFTYPAGAYACEVEVDPETGKV
CCCCEEECCEEEEEECCCCCCHHHHCCCHHHHCEECCCCCCCCCCCEEEEEEECCCCCCE
TIERFAAADDFGNIVNPMIVDGQVHGGIGQGIGQALLEGCVYDEDGQLLSASFMDYAMPR
EEEHHHHHHHHHHCCCCEEECCEECCCHHHHHHHHHHHCCEECCCCCEEHHHHHHHHCCC
ADDVPFYQVDHSCQTPCTHNPLGVKGCGEAGAIGSPPAVVNAVVDALRSAGKDVTHIDMP
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCC
LTPARVWAAMQG
CCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]