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The map label for this gene is coxS [H]

Identifier: 99081607

GI number: 99081607

Start: 1857876

End: 1858361

Strand: Reverse

Name: coxS [H]

Synonym: TM1040_1766

Alternate gene names: 99081607

Gene position: 1858361-1857876 (Counterclockwise)

Preceding gene: 99081608

Following gene: 99081606

Centisome position: 58.06

GC content: 60.91

Gene sequence:

>486_bases
ATGACGAAGGTCTCGATGACCGTGAATGGCAACCCCGTGTCCGGGAATGTCGAAGGTCGCACACTTTTGGTGTCATTCCT
GCGGGATCAGCAGGGGCTGACCGGCACCCATGTGGGCTGCGATACCAGCCAATGTGGCGCCTGCGTTGTCCATGTGGATG
GCAAGGCGGTAAAATCCTGCACCATGCTCGCGCTGGAAGCCGAAGGGGCCGAGGTCGCCACCATCGAGGGTCAAGCCGCA
CCCGACGGCACGCTCAATGCGATTCAGGCGGCATTTCAGGAACATCACGGGCTTCAGTGCGGGTTTTGCACGCCGGGCAT
GGTGATGTCGGCGGCGGCGCTCTTGAAAGAGAACCCCAAGCCCTCGGAAGCCGAGATCCGCCACTACCTTGAGGGCAATC
TCTGTCGCTGCACCGGCTATCACAACATCGTCAAAGCGATCATGGCAGCCTCCGGTCAGGACGTCTCTGCCATCGCGGCG
GAATAA

Upstream 100 bases:

>100_bases
GCGGATCCGAACCGCGTCGCATAAAATCCTCGCGCGATCTGCTGACCCGTGATTAACTGGGTTTAGCCAGATAAAAAGAA
TTCAAGCTAGGGAGGAATTT

Downstream 100 bases:

>100_bases
GCCCCAAGAAAGAGCACAGCCTGTCATCAGATGGGCTGCAAGTAACCCGTGACAATCCAGCGGATCAGTTCTGGTCTGGC
TGCGGCGGGAAGAGGAGCCC

Product: (2Fe-2S)-binding

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTKVSMTVNGNPVSGNVEGRTLLVSFLRDQQGLTGTHVGCDTSQCGACVVHVDGKAVKSCTMLALEAEGAEVATIEGQAA
PDGTLNAIQAAFQEHHGLQCGFCTPGMVMSAAALLKENPKPSEAEIRHYLEGNLCRCTGYHNIVKAIMAASGQDVSAIAA
E

Sequences:

>Translated_161_residues
MTKVSMTVNGNPVSGNVEGRTLLVSFLRDQQGLTGTHVGCDTSQCGACVVHVDGKAVKSCTMLALEAEGAEVATIEGQAA
PDGTLNAIQAAFQEHHGLQCGFCTPGMVMSAAALLKENPKPSEAEIRHYLEGNLCRCTGYHNIVKAIMAASGQDVSAIAA
E
>Mature_160_residues
TKVSMTVNGNPVSGNVEGRTLLVSFLRDQQGLTGTHVGCDTSQCGACVVHVDGKAVKSCTMLALEAEGAEVATIEGQAAP
DGTLNAIQAAFQEHHGLQCGFCTPGMVMSAAALLKENPKPSEAEIRHYLEGNLCRCTGYHNIVKAIMAASGQDVSAIAAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=159, Percent_Identity=33.9622641509434, Blast_Score=90, Evalue=7e-19,
Organism=Homo sapiens, GI71773480, Length=156, Percent_Identity=35.2564102564103, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=41.8181818181818, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=45.578231292517, Blast_Score=120, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17540638, Length=158, Percent_Identity=39.873417721519, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=164, Percent_Identity=35.9756097560976, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=159, Percent_Identity=35.8490566037736, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17737937, Length=149, Percent_Identity=38.9261744966443, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647199, Length=164, Percent_Identity=36.5853658536585, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24647193, Length=136, Percent_Identity=38.2352941176471, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647201, Length=165, Percent_Identity=32.7272727272727, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647195, Length=172, Percent_Identity=31.3953488372093, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24647197, Length=172, Percent_Identity=31.3953488372093, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16703; Mature: 16572

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVSMTVNGNPVSGNVEGRTLLVSFLRDQQGLTGTHVGCDTSQCGACVVHVDGKAVKSC
CCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHE
TMLALEAEGAEVATIEGQAAPDGTLNAIQAAFQEHHGLQCGFCTPGMVMSAAALLKENPK
EEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCC
PSEAEIRHYLEGNLCRCTGYHNIVKAIMAASGQDVSAIAAE
CCHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
TKVSMTVNGNPVSGNVEGRTLLVSFLRDQQGLTGTHVGCDTSQCGACVVHVDGKAVKSC
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHE
TMLALEAEGAEVATIEGQAAPDGTLNAIQAAFQEHHGLQCGFCTPGMVMSAAALLKENPK
EEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCC
PSEAEIRHYLEGNLCRCTGYHNIVKAIMAASGQDVSAIAAE
CCHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]