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The map label for this gene is grp [H]

Identifier: 99081596

GI number: 99081596

Start: 1846962

End: 1847441

Strand: Reverse

Name: grp [H]

Synonym: TM1040_1755

Alternate gene names: 99081596

Gene position: 1847441-1846962 (Counterclockwise)

Preceding gene: 99081603

Following gene: 99081591

Centisome position: 57.72

GC content: 59.17

Gene sequence:

>480_bases
ATGACAGTGCGGATCGACGCGACGGACCGGAAAATTCTGGCGGAACTCCAGCGTGATGCGGGGCAGTCGCTGGATGAAAT
CGCCAAGCAAGTGGGCAGTTCCAAGACCCCGGTCTGGAATCGGATCCGCAAATTGCGCGAGGCTGGCGTGGTCGGTAATC
AGACGGTGATCCTTGATGCCGAGGCCCTGGGGTTTGAGGCCTGTTTCTTCGTGCTGATCCGCACCTCGGAGCATGAAGCC
AGCTGGCAGGCATCCTTCCTCAAGGCCCTGCAGGAGCGCCCCGAAGTTCAGGAAGCGCACCGCCTTGCGGGTGACATCGA
CTATATCCTGAAGGTTCGGGTGAAGAACGCGCGCGCCTATGACAAATTCTACCAGGCGCTGATCTCAGAGGTGCGGGTCC
ACAATGTGACGGCGCTCTTGTCGATGGAAGAGATCAAATCGACCACGCATCTCCCGCTCGAGCAAATTCGCGTCGACTGA

Upstream 100 bases:

>100_bases
TATTCCCCTCTCTGTGCTATATGGGCCGGGAAATAAGGACACATGTCTCACTGCCTTTCGCCGTGAGGTCCGCGCGTCCT
GACTTGAGGAGAATTTTGGA

Downstream 100 bases:

>100_bases
TCTTGCCTGCTTTGGACGATGACCGAGTGGCTCAGCTCGTCGAACTCGCGGTGGATTTTGCGGATGAATTTTCGCGCAGG
AATGTGGTTTTGACCCTTGC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTVRIDATDRKILAELQRDAGQSLDEIAKQVGSSKTPVWNRIRKLREAGVVGNQTVILDAEALGFEACFFVLIRTSEHEA
SWQASFLKALQERPEVQEAHRLAGDIDYILKVRVKNARAYDKFYQALISEVRVHNVTALLSMEEIKSTTHLPLEQIRVD

Sequences:

>Translated_159_residues
MTVRIDATDRKILAELQRDAGQSLDEIAKQVGSSKTPVWNRIRKLREAGVVGNQTVILDAEALGFEACFFVLIRTSEHEA
SWQASFLKALQERPEVQEAHRLAGDIDYILKVRVKNARAYDKFYQALISEVRVHNVTALLSMEEIKSTTHLPLEQIRVD
>Mature_158_residues
TVRIDATDRKILAELQRDAGQSLDEIAKQVGSSKTPVWNRIRKLREAGVVGNQTVILDAEALGFEACFFVLIRTSEHEAS
WQASFLKALQERPEVQEAHRLAGDIDYILKVRVKNARAYDKFYQALISEVRVHNVTALLSMEEIKSTTHLPLEQIRVD

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=39.0728476821192, Blast_Score=126, Evalue=6e-31,
Organism=Escherichia coli, GI1787116, Length=148, Percent_Identity=35.1351351351351, Blast_Score=88, Evalue=2e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 18045; Mature: 17914

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRIDATDRKILAELQRDAGQSLDEIAKQVGSSKTPVWNRIRKLREAGVVGNQTVILDA
CEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEH
EALGFEACFFVLIRTSEHEASWQASFLKALQERPEVQEAHRLAGDIDYILKVRVKNARAY
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCHHH
DKFYQALISEVRVHNVTALLSMEEIKSTTHLPLEQIRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
TVRIDATDRKILAELQRDAGQSLDEIAKQVGSSKTPVWNRIRKLREAGVVGNQTVILDA
EEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEH
EALGFEACFFVLIRTSEHEASWQASFLKALQERPEVQEAHRLAGDIDYILKVRVKNARAY
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCHHH
DKFYQALISEVRVHNVTALLSMEEIKSTTHLPLEQIRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]