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The map label for this gene is arcB [H]

Identifier: 99081006

GI number: 99081006

Start: 1254443

End: 1255372

Strand: Reverse

Name: arcB [H]

Synonym: TM1040_1165

Alternate gene names: 99081006

Gene position: 1255372-1254443 (Counterclockwise)

Preceding gene: 99081008

Following gene: 99081005

Centisome position: 39.22

GC content: 63.12

Gene sequence:

>930_bases
ATGTCGTCTCGTCACTGTATTCTCGTTGGCGCACCCGTTGACAGCGGCAAGCGCCGCACGGGCTGTCTGATGGGCCCTGA
TGCCTACCGTACTGCCGGTCTCGCGCAGGCGCTCGAGAGCCTCGGCCATACGGTTGAGGACATCGGCAACGTGACCCCTG
CCCCGCATGCCCCCGACGATGGCACCGGCAAACTCCACGAGCCAAATTTAACGCGAGCCTGGACCGAAAGCCTGTCTGAA
GCGGCCGAGGCGGCCATGGCGCGGGGCATGCCCATTTTCTTGGGCGGCGATCACGCCCTTGCCCTGGGCACCGTGCACGG
GGTCGCAAACCACGCCGCCACCGTGGGACGACCGCTGTTTGTCCTCTGGCTCGACGCGCATAGTGACTTTCACTCGCTCG
AAAGCACGGAAACAGGCAATCTTCATGGCTGCCCGGTGCGCTATTTCACCAATCAGGCCCGGTTCGACAATTTCCCGCCC
GTGCCCAACCCGGTGCCGCCGGAAAACGTCTGCATGATCGGCCTGCGGTCGGTGGATACTCCCGAACGCGAAGCGATGGA
GCAGGTCGGCATTCATCGCCACGACATGCGCGACATTGACGAAAATGGCATTGCCCGGCCGCTGTCGGCCTTCCTTGAAA
AGGTCGCCGCGCAGAACGGCATGCTGCATGTGTCTCTGGATGTGGATTTCCTCGACCCCTCCGTTGCGCCTGCCGTGGGC
ACCACGGTTCCCGGCGGCGCCACCGTGCGCGAAGGCCATCTGGTCTGCGAAATCTTGCACGATAGCGGCTTGATGACCTC
GATGGACTTGGTGGAACTCAACCCCTTCCTCGACGAGCGTGGCCGTACAGCACATCTGATGGTGGATCTCTGTGCCTCTG
CCATGGGGCGGCGCGTCTTTGACCGACCGACCCGGAGCTACAACACATGA

Upstream 100 bases:

>100_bases
CCGTTTTGTGGTATCCGCTCCCCTTATGAGCAATTTGCTCTCTGTATTCCACCTCAAATCGGAGAAATATCAGAGACACC
CTCAATCAAGGAGATCTCGG

Downstream 100 bases:

>100_bases
GCACGCTTCAAGCTCCGGCAGCTGTGGTTATGGTGCGCCCGCATCATTTTACCTCAAACCCGGAAACGCGAGGGGACAAC
GCCTTTCAGGCGCAGGCCGA

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSSRHCILVGAPVDSGKRRTGCLMGPDAYRTAGLAQALESLGHTVEDIGNVTPAPHAPDDGTGKLHEPNLTRAWTESLSE
AAEAAMARGMPIFLGGDHALALGTVHGVANHAATVGRPLFVLWLDAHSDFHSLESTETGNLHGCPVRYFTNQARFDNFPP
VPNPVPPENVCMIGLRSVDTPEREAMEQVGIHRHDMRDIDENGIARPLSAFLEKVAAQNGMLHVSLDVDFLDPSVAPAVG
TTVPGGATVREGHLVCEILHDSGLMTSMDLVELNPFLDERGRTAHLMVDLCASAMGRRVFDRPTRSYNT

Sequences:

>Translated_309_residues
MSSRHCILVGAPVDSGKRRTGCLMGPDAYRTAGLAQALESLGHTVEDIGNVTPAPHAPDDGTGKLHEPNLTRAWTESLSE
AAEAAMARGMPIFLGGDHALALGTVHGVANHAATVGRPLFVLWLDAHSDFHSLESTETGNLHGCPVRYFTNQARFDNFPP
VPNPVPPENVCMIGLRSVDTPEREAMEQVGIHRHDMRDIDENGIARPLSAFLEKVAAQNGMLHVSLDVDFLDPSVAPAVG
TTVPGGATVREGHLVCEILHDSGLMTSMDLVELNPFLDERGRTAHLMVDLCASAMGRRVFDRPTRSYNT
>Mature_308_residues
SSRHCILVGAPVDSGKRRTGCLMGPDAYRTAGLAQALESLGHTVEDIGNVTPAPHAPDDGTGKLHEPNLTRAWTESLSEA
AEAAMARGMPIFLGGDHALALGTVHGVANHAATVGRPLFVLWLDAHSDFHSLESTETGNLHGCPVRYFTNQARFDNFPPV
PNPVPPENVCMIGLRSVDTPEREAMEQVGIHRHDMRDIDENGIARPLSAFLEKVAAQNGMLHVSLDVDFLDPSVAPAVGT
TVPGGATVREGHLVCEILHDSGLMTSMDLVELNPFLDERGRTAHLMVDLCASAMGRRVFDRPTRSYNT

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=303, Percent_Identity=37.2937293729373, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI10947139, Length=308, Percent_Identity=32.7922077922078, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI71996843, Length=200, Percent_Identity=30.5, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325146, Length=300, Percent_Identity=32, Blast_Score=142, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24638886, Length=284, Percent_Identity=32.3943661971831, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 33245; Mature: 33114

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRHCILVGAPVDSGKRRTGCLMGPDAYRTAGLAQALESLGHTVEDIGNVTPAPHAPDD
CCCCCEEEEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCC
GTGKLHEPNLTRAWTESLSEAAEAAMARGMPIFLGGDHALALGTVHGVANHAATVGRPLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHHHHHCCCEE
VLWLDAHSDFHSLESTETGNLHGCPVRYFTNQARFDNFPPVPNPVPPENVCMIGLRSVDT
EEEEECCCCHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
PEREAMEQVGIHRHDMRDIDENGIARPLSAFLEKVAAQNGMLHVSLDVDFLDPSVAPAVG
HHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCC
TTVPGGATVREGHLVCEILHDSGLMTSMDLVELNPFLDERGRTAHLMVDLCASAMGRRVF
CCCCCCCEEECCCEEEEEECCCCCEEECHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHH
DRPTRSYNT
HCCCCCCCC
>Mature Secondary Structure 
SSRHCILVGAPVDSGKRRTGCLMGPDAYRTAGLAQALESLGHTVEDIGNVTPAPHAPDD
CCCCEEEEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCC
GTGKLHEPNLTRAWTESLSEAAEAAMARGMPIFLGGDHALALGTVHGVANHAATVGRPLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHHHHHCCCEE
VLWLDAHSDFHSLESTETGNLHGCPVRYFTNQARFDNFPPVPNPVPPENVCMIGLRSVDT
EEEEECCCCHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
PEREAMEQVGIHRHDMRDIDENGIARPLSAFLEKVAAQNGMLHVSLDVDFLDPSVAPAVG
HHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCC
TTVPGGATVREGHLVCEILHDSGLMTSMDLVELNPFLDERGRTAHLMVDLCASAMGRRVF
CCCCCCCEEECCCEEEEEECCCCCEEECHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHH
DRPTRSYNT
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9375792 [H]