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The map label for this gene is mcpA [H]

Identifier: 99080680

GI number: 99080680

Start: 884254

End: 887037

Strand: Direct

Name: mcpA [H]

Synonym: TM1040_0839

Alternate gene names: 99080680

Gene position: 884254-887037 (Clockwise)

Preceding gene: 99080674

Following gene: 99080682

Centisome position: 27.62

GC content: 60.09

Gene sequence:

>2784_bases
ATGTCTGATCCGTCTGAAGTCCAATCAAGACCTCGCCGCAAATTTGGTATTTTCCGCAGTGTGCGCTCTAAACTCAGTGC
TGTCTTGGTGCTTCTGGCCGCGGGCATTACCCTATTTGGTTATATCACTTATGGGCTGCTCATGCAGGTCTCCGGGCATA
TTACCGAACTGAATGACGAAAACCTTCCCGACCTCGAAGTCTCGCAAGACATCACCCTTGCGGCCGATATGGCCAAAGAC
AGCATGATTACCATGCTGGTGGTGGATAATGCCGCGGGCATCGATCAGGCCATGGGCGAGGTGGACGCCGCGCGCACGGC
GCTGGGCAGTGCGATTGCAGAGCTCAACGACGATATCGAACCCCAGTTTTCCGCAAGCCTTGATGAGGTGTCTCAGGCTC
TTGCGGATCTTGCCGAGGCCCGCAGGGTCACTTTCGCAAGTGATGACCAGATTGAGGCCAGAGTACGCGACATGCAAAGC
ATCATCAGCGAACTCAGCGTCGTCATGGCGGAACTGTCGCGCTCTGCCGCCATCGAATTGCGACAGGGCGCCGAGGCGAC
AGATCAGAAAATTGACAATACGGTCACGCGCCTGGTCGAGGTGGATTTTTACAATCAATCGCTCCTGCTGGAGGCCCAGG
CCGAACTCAATCTGCTGACCGGCGCCGCCGTGTCGGCCGGAGGGACCAAAGACCCCGAGACCCTGGCCCAGATAGAGGCC
ATGGCTGAAAAATCGCGCGACCGTCTCTTGGAAATCACCGACATTATCAGCGAACGCGCTCCCGAGATTTTTGACACCTC
ACTCCTGATTACGGCTGTGTTTACGCTCGAGACGGTGCTGGCGCAGAGCCTGTTTCCCTCCGAAACCCTGCGCAAGGCTG
CATTGAGCGCCCGCGCCGACACAGCAAAAGCCATTGATACGGCAATCAACGCCCAGATGCGCAGTTTGCTGGCATCGGTT
AACGCGGCGAAGGATGCGAACGGCGATGCGCTCGAGTTGCTGCTCACCAATGAGGTGGGCTTTCTGCGAGAGCTGGTTGA
GATCGGGATCGCGATCAACATGTTCCAGGTTGCCGCTCTTGATGCGGCTACTTCCGATGACGAAGCCAGCGTAAGTGACG
CCGAGAAGGGAATGGTTGAAGCAGGCGCCCTTTTTGCAAAGTATCAGGATTTTCGCGATGGGCGGGTTGTCGAGTTCCTC
TCGCGCCTGAGCGATCTGAATGATCCCGAAACGGGCCTCGCAGCTCTTCAGATCAAAGGCATCAAAGCTGCAGAAGCATC
AGACGCGGCCACCCTCAATGCACGCACTTCGGTCGAGGCGATCTCCCAGCGCGCTGCGGAGTTCACCGCCAGCACACTCA
GTGAAATCGATGTGATGACGGATGAAATCTTTGATGAAGTCGAGTTGATGGTGCGGGACCTAGTTGTCTCAGCCGCTGTT
GCAGGCGTGTGTTTCCTTGCGATATTTTCCGTTATTCAGCTTCTGATCCTGCGTCCGTTGAACCGGATCAGTGCGAGCAC
GGAACGGCTTGCGGAGGGGGATCGCAGCCCTGTCACCGGGTTTGAACGCACCAGTACAGAGATTTACCGGATCGCGCGCT
CGCTGTCGGTGTTCCGCGATGGGATCGTCGAAAAAGAAGAGCTCGAAGAGATGGCGGCCGCCGAACGGCAGGAGCGCGAA
CGGGTGCAGGCCAAGGCGGTCGAGGCGCTGGGCACGGGGCTGGAGCGGCTCTCCAGCGGGGATCTGACCGGCCACATCCA
CGAAGAACTCGGCGAGGGCTATGACCGGCTGCGGCTCGACTTCAACCGCACCCTCGACACCTTGAATGACACCGTCGGCC
AGGTGATCGACACCTCTGCCTCCATTCGCAACGGCGCCTCGGAAATCAGCCAGGCCTCGCAGGACCTGTCGCATCGCACC
GAAAGCCAGGCCGCGACGCTCGAAGAGACCGCCGCCGCATTGGATGAGATGACGGCCAGCGTGACCTCTGCCGCGGAAGG
CGCGCGCGATGTGGAACGCACCTCGAACGAGGCGCGCAGCGAGGCCGAAGCCAGTGGCGATATCGTGCGCAGCGCTGTTT
CGGCGATGACCGAGATCGAACAGAGTTCGGGCAAGATCGCGCAGATCATCTCGGTGATTGACGATATCGCCTTTCAGACT
AACCTCTTGGCACTCAATGCCGGTGTCGAGGCGGCCCGGGCCGGGGAGGCGGGGCGTGGCTTTGCGGTTGTGGCCTCCGA
GGTGCGGGGCCTTGCGCAGCGCTCTTCGGATGCGGCGCTGGAAATCAAGAATCTGATCAGCGACAGCTCGAAACAGGTGG
AGCGTGGTGTTGATCTTGTGGGCAAGGCCGGTGAGGCGCTGGACAACATCCTGAACCGCGTGAGTCATGTCTCCGAGCTG
ATTTCCGGGATCGCCACCGGTGCGCAGGAGCAATCCACGGGGCTCTTGGAAATCAACACGGGTATGAACCAGCTGGATCA
GGTGACCCAGCAAAACGCTGCCATGGTCGAGGAGGCCACTGCGGCGAGCCAGCTCCTGAACACGGATGCGGAGACGCTTG
CGGATCTGGTGGCCCGGTTCCAGACGGCAAATACGGCGCGGACCCCTGCCGCGGGCGCTGGGGATGTGGGCGAGGACGCC
GGATCAGAGGCGCTTGCTCCCACAAGCTGGGGCGATGCACAGGACATCGAGTGGGAGGCCACCGAGGTCGAAGAGCCCTT
TGTCCCGGAGCAGACAGACTGGTCCGACTTTGATGGCGACGACACTCAGGCAACCGGGACGTAA

Upstream 100 bases:

>100_bases
TCCGGGCCTTCGGCCTTCGTTGCGGGCACACAGTCAGTTTTCATGTTCAGTCACATCAAGGCGCGTCGCGCGCCGTTTGG
TCAAAAAGTGAAGTGTGAAA

Downstream 100 bases:

>100_bases
AAGACCCTTTGAGGGCCTGACTCGGGTTGCGCCGGGTGCTCGAATGCGTCGACCCTATTGGGCATTTTGAAACGCGCGTA
GCTGATCAAAGTTTGAGGAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 927; Mature: 926

Protein sequence:

>927_residues
MSDPSEVQSRPRRKFGIFRSVRSKLSAVLVLLAAGITLFGYITYGLLMQVSGHITELNDENLPDLEVSQDITLAADMAKD
SMITMLVVDNAAGIDQAMGEVDAARTALGSAIAELNDDIEPQFSASLDEVSQALADLAEARRVTFASDDQIEARVRDMQS
IISELSVVMAELSRSAAIELRQGAEATDQKIDNTVTRLVEVDFYNQSLLLEAQAELNLLTGAAVSAGGTKDPETLAQIEA
MAEKSRDRLLEITDIISERAPEIFDTSLLITAVFTLETVLAQSLFPSETLRKAALSARADTAKAIDTAINAQMRSLLASV
NAAKDANGDALELLLTNEVGFLRELVEIGIAINMFQVAALDAATSDDEASVSDAEKGMVEAGALFAKYQDFRDGRVVEFL
SRLSDLNDPETGLAALQIKGIKAAEASDAATLNARTSVEAISQRAAEFTASTLSEIDVMTDEIFDEVELMVRDLVVSAAV
AGVCFLAIFSVIQLLILRPLNRISASTERLAEGDRSPVTGFERTSTEIYRIARSLSVFRDGIVEKEELEEMAAAERQERE
RVQAKAVEALGTGLERLSSGDLTGHIHEELGEGYDRLRLDFNRTLDTLNDTVGQVIDTSASIRNGASEISQASQDLSHRT
ESQAATLEETAAALDEMTASVTSAAEGARDVERTSNEARSEAEASGDIVRSAVSAMTEIEQSSGKIAQIISVIDDIAFQT
NLLALNAGVEAARAGEAGRGFAVVASEVRGLAQRSSDAALEIKNLISDSSKQVERGVDLVGKAGEALDNILNRVSHVSEL
ISGIATGAQEQSTGLLEINTGMNQLDQVTQQNAAMVEEATAASQLLNTDAETLADLVARFQTANTARTPAAGAGDVGEDA
GSEALAPTSWGDAQDIEWEATEVEEPFVPEQTDWSDFDGDDTQATGT

Sequences:

>Translated_927_residues
MSDPSEVQSRPRRKFGIFRSVRSKLSAVLVLLAAGITLFGYITYGLLMQVSGHITELNDENLPDLEVSQDITLAADMAKD
SMITMLVVDNAAGIDQAMGEVDAARTALGSAIAELNDDIEPQFSASLDEVSQALADLAEARRVTFASDDQIEARVRDMQS
IISELSVVMAELSRSAAIELRQGAEATDQKIDNTVTRLVEVDFYNQSLLLEAQAELNLLTGAAVSAGGTKDPETLAQIEA
MAEKSRDRLLEITDIISERAPEIFDTSLLITAVFTLETVLAQSLFPSETLRKAALSARADTAKAIDTAINAQMRSLLASV
NAAKDANGDALELLLTNEVGFLRELVEIGIAINMFQVAALDAATSDDEASVSDAEKGMVEAGALFAKYQDFRDGRVVEFL
SRLSDLNDPETGLAALQIKGIKAAEASDAATLNARTSVEAISQRAAEFTASTLSEIDVMTDEIFDEVELMVRDLVVSAAV
AGVCFLAIFSVIQLLILRPLNRISASTERLAEGDRSPVTGFERTSTEIYRIARSLSVFRDGIVEKEELEEMAAAERQERE
RVQAKAVEALGTGLERLSSGDLTGHIHEELGEGYDRLRLDFNRTLDTLNDTVGQVIDTSASIRNGASEISQASQDLSHRT
ESQAATLEETAAALDEMTASVTSAAEGARDVERTSNEARSEAEASGDIVRSAVSAMTEIEQSSGKIAQIISVIDDIAFQT
NLLALNAGVEAARAGEAGRGFAVVASEVRGLAQRSSDAALEIKNLISDSSKQVERGVDLVGKAGEALDNILNRVSHVSEL
ISGIATGAQEQSTGLLEINTGMNQLDQVTQQNAAMVEEATAASQLLNTDAETLADLVARFQTANTARTPAAGAGDVGEDA
GSEALAPTSWGDAQDIEWEATEVEEPFVPEQTDWSDFDGDDTQATGT
>Mature_926_residues
SDPSEVQSRPRRKFGIFRSVRSKLSAVLVLLAAGITLFGYITYGLLMQVSGHITELNDENLPDLEVSQDITLAADMAKDS
MITMLVVDNAAGIDQAMGEVDAARTALGSAIAELNDDIEPQFSASLDEVSQALADLAEARRVTFASDDQIEARVRDMQSI
ISELSVVMAELSRSAAIELRQGAEATDQKIDNTVTRLVEVDFYNQSLLLEAQAELNLLTGAAVSAGGTKDPETLAQIEAM
AEKSRDRLLEITDIISERAPEIFDTSLLITAVFTLETVLAQSLFPSETLRKAALSARADTAKAIDTAINAQMRSLLASVN
AAKDANGDALELLLTNEVGFLRELVEIGIAINMFQVAALDAATSDDEASVSDAEKGMVEAGALFAKYQDFRDGRVVEFLS
RLSDLNDPETGLAALQIKGIKAAEASDAATLNARTSVEAISQRAAEFTASTLSEIDVMTDEIFDEVELMVRDLVVSAAVA
GVCFLAIFSVIQLLILRPLNRISASTERLAEGDRSPVTGFERTSTEIYRIARSLSVFRDGIVEKEELEEMAAAERQERER
VQAKAVEALGTGLERLSSGDLTGHIHEELGEGYDRLRLDFNRTLDTLNDTVGQVIDTSASIRNGASEISQASQDLSHRTE
SQAATLEETAAALDEMTASVTSAAEGARDVERTSNEARSEAEASGDIVRSAVSAMTEIEQSSGKIAQIISVIDDIAFQTN
LLALNAGVEAARAGEAGRGFAVVASEVRGLAQRSSDAALEIKNLISDSSKQVERGVDLVGKAGEALDNILNRVSHVSELI
SGIATGAQEQSTGLLEINTGMNQLDQVTQQNAAMVEEATAASQLLNTDAETLADLVARFQTANTARTPAAGAGDVGEDAG
SEALAPTSWGDAQDIEWEATEVEEPFVPEQTDWSDFDGDDTQATGT

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=274, Percent_Identity=47.8102189781022, Blast_Score=209, Evalue=7e-55,
Organism=Escherichia coli, GI1787690, Length=301, Percent_Identity=42.5249169435216, Blast_Score=209, Evalue=8e-55,
Organism=Escherichia coli, GI2367378, Length=263, Percent_Identity=47.5285171102662, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1788194, Length=253, Percent_Identity=47.4308300395257, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=38.4, Blast_Score=163, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 98848; Mature: 98717

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPSEVQSRPRRKFGIFRSVRSKLSAVLVLLAAGITLFGYITYGLLMQVSGHITELNDE
CCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
NLPDLEVSQDITLAADMAKDSMITMLVVDNAAGIDQAMGEVDAARTALGSAIAELNDDIE
CCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PQFSASLDEVSQALADLAEARRVTFASDDQIEARVRDMQSIISELSVVMAELSRSAAIEL
CHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGAEATDQKIDNTVTRLVEVDFYNQSLLLEAQAELNLLTGAAVSAGGTKDPETLAQIEA
HCCCCHHHHHHHHHHHHHHHHEECCCHHEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
MAEKSRDRLLEITDIISERAPEIFDTSLLITAVFTLETVLAQSLFPSETLRKAALSARAD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TAKAIDTAINAQMRSLLASVNAAKDANGDALELLLTNEVGFLRELVEIGIAINMFQVAAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
DAATSDDEASVSDAEKGMVEAGALFAKYQDFRDGRVVEFLSRLSDLNDPETGLAALQIKG
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECC
IKAAEASDAATLNARTSVEAISQRAAEFTASTLSEIDVMTDEIFDEVELMVRDLVVSAAV
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVCFLAIFSVIQLLILRPLNRISASTERLAEGDRSPVTGFERTSTEIYRIARSLSVFRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GIVEKEELEEMAAAERQERERVQAKAVEALGTGLERLSSGDLTGHIHEELGEGYDRLRLD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHH
FNRTLDTLNDTVGQVIDTSASIRNGASEISQASQDLSHRTESQAATLEETAAALDEMTAS
HHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTSAAEGARDVERTSNEARSEAEASGDIVRSAVSAMTEIEQSSGKIAQIISVIDDIAFQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NLLALNAGVEAARAGEAGRGFAVVASEVRGLAQRSSDAALEIKNLISDSSKQVERGVDLV
HHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHH
GKAGEALDNILNRVSHVSELISGIATGAQEQSTGLLEINTGMNQLDQVTQQNAAMVEEAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCHHHHHHHHHHHHHHHHHHH
AASQLLNTDAETLADLVARFQTANTARTPAAGAGDVGEDAGSEALAPTSWGDAQDIEWEA
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
TEVEEPFVPEQTDWSDFDGDDTQATGT
HCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDPSEVQSRPRRKFGIFRSVRSKLSAVLVLLAAGITLFGYITYGLLMQVSGHITELNDE
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
NLPDLEVSQDITLAADMAKDSMITMLVVDNAAGIDQAMGEVDAARTALGSAIAELNDDIE
CCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PQFSASLDEVSQALADLAEARRVTFASDDQIEARVRDMQSIISELSVVMAELSRSAAIEL
CHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGAEATDQKIDNTVTRLVEVDFYNQSLLLEAQAELNLLTGAAVSAGGTKDPETLAQIEA
HCCCCHHHHHHHHHHHHHHHHEECCCHHEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
MAEKSRDRLLEITDIISERAPEIFDTSLLITAVFTLETVLAQSLFPSETLRKAALSARAD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TAKAIDTAINAQMRSLLASVNAAKDANGDALELLLTNEVGFLRELVEIGIAINMFQVAAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
DAATSDDEASVSDAEKGMVEAGALFAKYQDFRDGRVVEFLSRLSDLNDPETGLAALQIKG
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECC
IKAAEASDAATLNARTSVEAISQRAAEFTASTLSEIDVMTDEIFDEVELMVRDLVVSAAV
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVCFLAIFSVIQLLILRPLNRISASTERLAEGDRSPVTGFERTSTEIYRIARSLSVFRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GIVEKEELEEMAAAERQERERVQAKAVEALGTGLERLSSGDLTGHIHEELGEGYDRLRLD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHH
FNRTLDTLNDTVGQVIDTSASIRNGASEISQASQDLSHRTESQAATLEETAAALDEMTAS
HHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTSAAEGARDVERTSNEARSEAEASGDIVRSAVSAMTEIEQSSGKIAQIISVIDDIAFQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NLLALNAGVEAARAGEAGRGFAVVASEVRGLAQRSSDAALEIKNLISDSSKQVERGVDLV
HHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHH
GKAGEALDNILNRVSHVSELISGIATGAQEQSTGLLEINTGMNQLDQVTQQNAAMVEEAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCHHHHHHHHHHHHHHHHHHH
AASQLLNTDAETLADLVARFQTANTARTPAAGAGDVGEDAGSEALAPTSWGDAQDIEWEA
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
TEVEEPFVPEQTDWSDFDGDDTQATGT
HCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]