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The map label for this gene is ftsZ [H]

Identifier: 99080530

GI number: 99080530

Start: 738085

End: 739758

Strand: Direct

Name: ftsZ [H]

Synonym: TM1040_0689

Alternate gene names: 99080530

Gene position: 738085-739758 (Clockwise)

Preceding gene: 99080529

Following gene: 99080531

Centisome position: 23.06

GC content: 62.96

Gene sequence:

>1674_bases
ATGACCCTGAACCTTTCGATGCCCGGACAAGAAGAGCTGAGCCCCAAGATCACCGTCTTTGGGGTTGGTGGTGCGGGCGG
GAACGCCGTCAACAACATGATCGCCAAGCAGCTCGAGGGTGTGGATTTTGTTGTTGCCAACACCGACGCACAGGCGTTGC
AGCAAAACGCAGCCAAAAACCGGGTGCAGCTCGGCGTCAAGGTGACCGAAGGCCTTGGCGCAGGTGCACGCCCCTCGGTC
GGCTCTGCTGCCGCTGAGGAAAGCATTGAGCAGATCGTTGACCATCTCGCGGGCGCGCACATGTGCTTTATCACCGCTGG
CATGGGCGGGGGCACCGGAACCGGCGCCGCCCCGATCATCGCGCAGGCCGCGCGTGAGCTTGGTGTGCTGACCGTCGGGG
TTGTCACTAAGCCGTTCCAGTTCGAAGGCGCCAAGCGGATGCGCCAGGCCGAAGAGGGCGTCGAGAGCCTTCAGAAGGTT
GTTGATACGCTTATCATCATTCCGAACCAGAACCTGTTCCGTCTGGCCAATGAGAAGACCACCTTCACCGAAGCCTTCTC
TATGGCGGACGATGTGCTTTATCAGGGTGTCAAAGGCGTGACCGACCTGATGGTGCGTCCGGGCCTCATCAACCTCGACT
TTGCGGATGTACGTGCCGTGATGGACGAGATGGGCAAAGCGATGATGGGCACTGGTGAGGCCGAGGGCGAAGATCGCGCC
ATCCAGGCCGCCGAAAAAGCCATCGCCAACCCGCTGCTGGACGAAATCAGTCTCAAGGGCGCCAAGGGCGTGCTCATCAA
CATCACCGGTGCGCATGATCTGACCCTGTTTGAACTGGACGAAGCGGCCAACCGCATTCGCGAAGAAGTTGATCCCAACG
CCAACATCATCGTGGGCTCCACGCTCGACACCGAGATGGAAGGCAAGATGCGCGTCTCCGTGGTTGCAACCGGGATTGAT
GCGTCTGAGGATGCCAATGAGGTGCCGGTCCCGCGTCGCCCGATGTCCGCGCCGCTGACCAAAACCGTGAGCGTCGAAGA
AAATCGTCAGGCGCCGCTTGAACTCACTGAGCAGGTAGACGCTCCGACGCCCGTCGCCGCGCAAGCCGGTGCAGGCCAGG
AACCTTCGTTGTTTTCCGAGTTTGACGCTGATGAAGGCGCTGCAAGCGACGATGTGATCGAGGACACCAACGAAGCTGCA
GATGCCAATGATGGCCTGCCGCCCCCGGCGTACCAGCCGCAGGCACAGCAGCCCGCACCTCAGCCGCAACCGCAGCCTGC
ACAACCGGCTGTGACCCAGGCCGAAGTCTTTGTGGCACCGCGCGCCCCGGCTCCGGGCACCCCGTCGCAGGATGCCATCG
TGCGCCTGCGTGAGGCGGCACAGCGCCACCAGGCCTCGCAGCAACCGCAGCGCCCGGCACAGCAACCCGCCGCAGCGGCG
CCGCAGCAAGAGCGTCGCAGCGCAGAAGCGCAGGAGCAGCGCCGTTTCGGCCTGAACTCGCTGATCAACCGGATGACTGG
CCACCCGCAAGAGACGTCGCAAAACCGTCCTCAAGCGGCGCAACGGGTCCAGCCCAGCATGCAGAGCGCACAGCCGCAGC
AGGCTGAGCAGCCCCATGACGAGGATCAAGAGCGCATCGAAATCCCGGCATTCCTGCGCCGTCAAGCCAACTGA

Upstream 100 bases:

>100_bases
CTTTTGGGGATGACGAGACTCACGCGTCGCGGTAGGATTAAGGCAGAAGAGTGACAATCGACGCCCTTGCGGGAGGGCTA
AAAACACAGGCGGAAAAAGC

Downstream 100 bases:

>100_bases
TCGGTCATAAATCACACCCAAAGAGACCGCCGAGAGGCGGTCTTTTTTTGTTTTGTTTCAAATGAGTAGAGTGGCTTCGG
CGGGGTTTTGCCAAGTTGTA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MTLNLSMPGQEELSPKITVFGVGGAGGNAVNNMIAKQLEGVDFVVANTDAQALQQNAAKNRVQLGVKVTEGLGAGARPSV
GSAAAEESIEQIVDHLAGAHMCFITAGMGGGTGTGAAPIIAQAARELGVLTVGVVTKPFQFEGAKRMRQAEEGVESLQKV
VDTLIIIPNQNLFRLANEKTTFTEAFSMADDVLYQGVKGVTDLMVRPGLINLDFADVRAVMDEMGKAMMGTGEAEGEDRA
IQAAEKAIANPLLDEISLKGAKGVLINITGAHDLTLFELDEAANRIREEVDPNANIIVGSTLDTEMEGKMRVSVVATGID
ASEDANEVPVPRRPMSAPLTKTVSVEENRQAPLELTEQVDAPTPVAAQAGAGQEPSLFSEFDADEGAASDDVIEDTNEAA
DANDGLPPPAYQPQAQQPAPQPQPQPAQPAVTQAEVFVAPRAPAPGTPSQDAIVRLREAAQRHQASQQPQRPAQQPAAAA
PQQERRSAEAQEQRRFGLNSLINRMTGHPQETSQNRPQAAQRVQPSMQSAQPQQAEQPHDEDQERIEIPAFLRRQAN

Sequences:

>Translated_557_residues
MTLNLSMPGQEELSPKITVFGVGGAGGNAVNNMIAKQLEGVDFVVANTDAQALQQNAAKNRVQLGVKVTEGLGAGARPSV
GSAAAEESIEQIVDHLAGAHMCFITAGMGGGTGTGAAPIIAQAARELGVLTVGVVTKPFQFEGAKRMRQAEEGVESLQKV
VDTLIIIPNQNLFRLANEKTTFTEAFSMADDVLYQGVKGVTDLMVRPGLINLDFADVRAVMDEMGKAMMGTGEAEGEDRA
IQAAEKAIANPLLDEISLKGAKGVLINITGAHDLTLFELDEAANRIREEVDPNANIIVGSTLDTEMEGKMRVSVVATGID
ASEDANEVPVPRRPMSAPLTKTVSVEENRQAPLELTEQVDAPTPVAAQAGAGQEPSLFSEFDADEGAASDDVIEDTNEAA
DANDGLPPPAYQPQAQQPAPQPQPQPAQPAVTQAEVFVAPRAPAPGTPSQDAIVRLREAAQRHQASQQPQRPAQQPAAAA
PQQERRSAEAQEQRRFGLNSLINRMTGHPQETSQNRPQAAQRVQPSMQSAQPQQAEQPHDEDQERIEIPAFLRRQAN
>Mature_556_residues
TLNLSMPGQEELSPKITVFGVGGAGGNAVNNMIAKQLEGVDFVVANTDAQALQQNAAKNRVQLGVKVTEGLGAGARPSVG
SAAAEESIEQIVDHLAGAHMCFITAGMGGGTGTGAAPIIAQAARELGVLTVGVVTKPFQFEGAKRMRQAEEGVESLQKVV
DTLIIIPNQNLFRLANEKTTFTEAFSMADDVLYQGVKGVTDLMVRPGLINLDFADVRAVMDEMGKAMMGTGEAEGEDRAI
QAAEKAIANPLLDEISLKGAKGVLINITGAHDLTLFELDEAANRIREEVDPNANIIVGSTLDTEMEGKMRVSVVATGIDA
SEDANEVPVPRRPMSAPLTKTVSVEENRQAPLELTEQVDAPTPVAAQAGAGQEPSLFSEFDADEGAASDDVIEDTNEAAD
ANDGLPPPAYQPQAQQPAPQPQPQPAQPAVTQAEVFVAPRAPAPGTPSQDAIVRLREAAQRHQASQQPQRPAQQPAAAAP
QQERRSAEAQEQRRFGLNSLINRMTGHPQETSQNRPQAAQRVQPSMQSAQPQQAEQPHDEDQERIEIPAFLRRQAN

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=292, Percent_Identity=53.7671232876712, Blast_Score=287, Evalue=1e-78,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 59148; Mature: 59017

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNLSMPGQEELSPKITVFGVGGAGGNAVNNMIAKQLEGVDFVVANTDAQALQQNAAKN
CEEECCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
RVQLGVKVTEGLGAGARPSVGSAAAEESIEQIVDHLAGAHMCFITAGMGGGTGTGAAPII
HEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHH
AQAARELGVLTVGVVTKPFQFEGAKRMRQAEEGVESLQKVVDTLIIIPNQNLFRLANEKT
HHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCCH
TFTEAFSMADDVLYQGVKGVTDLMVRPGLINLDFADVRAVMDEMGKAMMGTGEAEGEDRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHH
IQAAEKAIANPLLDEISLKGAKGVLINITGAHDLTLFELDEAANRIREEVDPNANIIVGS
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCEEEEC
TLDTEMEGKMRVSVVATGIDASEDANEVPVPRRPMSAPLTKTVSVEENRQAPLELTEQVD
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCC
APTPVAAQAGAGQEPSLFSEFDADEGAASDDVIEDTNEAADANDGLPPPAYQPQAQQPAP
CCCCCHHCCCCCCCCCHHHHCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCCCCC
QPQPQPAQPAVTQAEVFVAPRAPAPGTPSQDAIVRLREAAQRHQASQQPQRPAQQPAAAA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCC
PQQERRSAEAQEQRRFGLNSLINRMTGHPQETSQNRPQAAQRVQPSMQSAQPQQAEQPHD
CHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHCCCCHHHHHHHCHHHHHCCCHHHCCCCC
EDQERIEIPAFLRRQAN
CCHHHCCHHHHHHHCCC
>Mature Secondary Structure 
TLNLSMPGQEELSPKITVFGVGGAGGNAVNNMIAKQLEGVDFVVANTDAQALQQNAAKN
EEECCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHH
RVQLGVKVTEGLGAGARPSVGSAAAEESIEQIVDHLAGAHMCFITAGMGGGTGTGAAPII
HEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHH
AQAARELGVLTVGVVTKPFQFEGAKRMRQAEEGVESLQKVVDTLIIIPNQNLFRLANEKT
HHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCCH
TFTEAFSMADDVLYQGVKGVTDLMVRPGLINLDFADVRAVMDEMGKAMMGTGEAEGEDRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHH
IQAAEKAIANPLLDEISLKGAKGVLINITGAHDLTLFELDEAANRIREEVDPNANIIVGS
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCEEEEC
TLDTEMEGKMRVSVVATGIDASEDANEVPVPRRPMSAPLTKTVSVEENRQAPLELTEQVD
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCC
APTPVAAQAGAGQEPSLFSEFDADEGAASDDVIEDTNEAADANDGLPPPAYQPQAQQPAP
CCCCCHHCCCCCCCCCHHHHCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCCCCC
QPQPQPAQPAVTQAEVFVAPRAPAPGTPSQDAIVRLREAAQRHQASQQPQRPAQQPAAAA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCC
PQQERRSAEAQEQRRFGLNSLINRMTGHPQETSQNRPQAAQRVQPSMQSAQPQQAEQPHD
CHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHCCCCHHHHHHHCHHHHHCCCHHHCCCCC
EDQERIEIPAFLRRQAN
CCHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]