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The map label for this gene is ftsA [H]

Identifier: 99080529

GI number: 99080529

Start: 736308

End: 737660

Strand: Direct

Name: ftsA [H]

Synonym: TM1040_0688

Alternate gene names: 99080529

Gene position: 736308-737660 (Clockwise)

Preceding gene: 99080528

Following gene: 99080530

Centisome position: 23.0

GC content: 62.01

Gene sequence:

>1353_bases
ATGAGAGCTCCTATTGATATGACAGACCTGTATCAATCCCAACGTGCGATGCGGCAAATGCGCCGCCAGGCGATGCAACG
CGGTGTGGTGGCCATTCTGGATGTGGGCAGTTCCAAGATATCCTGCTTGGTACTGAGGTTTGATGGCGTCACGCGCCTGA
GCGAAGACAATTCGATCGGGTCTCTTGCGGGGCAGTCGGGTTTTCGCGTGATTGGCGCGGCGACGACCCGTTCGCGCGGG
GTGCAGTTTGGCGAAGTCTGCGCCATGCAGGAAACCGAGCGCGCCATTCGCACCGCCGTGCAGGCGGCGCAAAAGATGGC
TGAAGTCCGGGTTGACCATGTGATCGCTTGTTTCGCCGGCGCACTGCCGCGGTCTTATGGGCTTGATGCCACGGTGGAAC
TCGAAGGGCAGGAAGTCACCGAGAATGAGATCGCACGTGTGCTGGCGGCCTGCGAAGTGCCGGAATACGGCGCCGGGCGC
GAGGTTTTGCACGCGCAACCTGTGAACTTCGCGCTCGACAACCGATCTGGTCTTGAAGACCCGCGCGGCCAGATGGGGCA
GGCGCTCTCTGTTGATATGCATATGCTCACGGTCGAAGCTGCCGCCATCCAGAACCTGGTGCGCTGTGTGCAGCGCTGCG
ATCTGGAACTGGCGGGGATTGCCTCTTCGGCCTATGTCTCGGGGATCTCAGCCCTTGTGGAAGATGAGCAAGAACTCGGC
GCGGCCTGCATCGACATGGGGGGCGGCACCACTTCGGTGTCGATCTTCATGAAGAAACACATGATCTATGCCGATGCGGT
GCGCATGGGGGGGGATCACGTTACCAGTGATATTTCCATGGGGCTCGGCGTGCCCACAGCAACTGCCGAGCGGATCAAGA
CCATGTCTGGCGGCGTACATGCGACTGGTGCGGATGATCGCGACATGATCGACATCGGCGGCGAGACAGGCGATTGGGAG
CGGGATCGCCGCACCGTTAGCCGGGCGGAGCTCATTGGGATCATGCGTCCCCGCGTCGAGGAAATCCTGGAAGAAGTGCG
CGTCCGTCTCGATGCCGCCGGATTCGACCATCTGCCGAGCCAGCAAATCGTGCTGACCGGCGGCTCCAGCCAGATCCTCG
GGCTTGATGGTCTTGCAAGCCGCATACTCGGCCAGCAAGTGCGCCTTGGGCGACCGATGCGTGTGCATGGTCTGCCGCAG
GCTGTGACCGGGCCGGGCTTTGCCTCTGCCGTCGGCATGTGTCTGTTTGCAGCGCATCCGCAGGACGAGTGGTGGGATTT
CGACGCGCCGGTGGACCGGATGGCTGGCGGCTCGATGCGCCGCGTCGTGCGTTGGTTTAAGGACAACTGGTGA

Upstream 100 bases:

>100_bases
GAACGGGATGTCGCAGTCGTGGATCTGCGCCTGCCCACGCGTCTAACCGTTAGAATGAACGCGCCAGCCGTAGAGGACTG
GTGGCGCATCCGTCAATTGA

Downstream 100 bases:

>100_bases
TCTGCGCGGCGCTCGGCAAACCTTTGCCGATTGCCGCGGGCCTCCACAAAGTTATGCACAGGTTTCCCACAGCTTCTCCA
CAATGGCCGTGACAGGCCTC

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRAPIDMTDLYQSQRAMRQMRRQAMQRGVVAILDVGSSKISCLVLRFDGVTRLSEDNSIGSLAGQSGFRVIGAATTRSRG
VQFGEVCAMQETERAIRTAVQAAQKMAEVRVDHVIACFAGALPRSYGLDATVELEGQEVTENEIARVLAACEVPEYGAGR
EVLHAQPVNFALDNRSGLEDPRGQMGQALSVDMHMLTVEAAAIQNLVRCVQRCDLELAGIASSAYVSGISALVEDEQELG
AACIDMGGGTTSVSIFMKKHMIYADAVRMGGDHVTSDISMGLGVPTATAERIKTMSGGVHATGADDRDMIDIGGETGDWE
RDRRTVSRAELIGIMRPRVEEILEEVRVRLDAAGFDHLPSQQIVLTGGSSQILGLDGLASRILGQQVRLGRPMRVHGLPQ
AVTGPGFASAVGMCLFAAHPQDEWWDFDAPVDRMAGGSMRRVVRWFKDNW

Sequences:

>Translated_450_residues
MRAPIDMTDLYQSQRAMRQMRRQAMQRGVVAILDVGSSKISCLVLRFDGVTRLSEDNSIGSLAGQSGFRVIGAATTRSRG
VQFGEVCAMQETERAIRTAVQAAQKMAEVRVDHVIACFAGALPRSYGLDATVELEGQEVTENEIARVLAACEVPEYGAGR
EVLHAQPVNFALDNRSGLEDPRGQMGQALSVDMHMLTVEAAAIQNLVRCVQRCDLELAGIASSAYVSGISALVEDEQELG
AACIDMGGGTTSVSIFMKKHMIYADAVRMGGDHVTSDISMGLGVPTATAERIKTMSGGVHATGADDRDMIDIGGETGDWE
RDRRTVSRAELIGIMRPRVEEILEEVRVRLDAAGFDHLPSQQIVLTGGSSQILGLDGLASRILGQQVRLGRPMRVHGLPQ
AVTGPGFASAVGMCLFAAHPQDEWWDFDAPVDRMAGGSMRRVVRWFKDNW
>Mature_450_residues
MRAPIDMTDLYQSQRAMRQMRRQAMQRGVVAILDVGSSKISCLVLRFDGVTRLSEDNSIGSLAGQSGFRVIGAATTRSRG
VQFGEVCAMQETERAIRTAVQAAQKMAEVRVDHVIACFAGALPRSYGLDATVELEGQEVTENEIARVLAACEVPEYGAGR
EVLHAQPVNFALDNRSGLEDPRGQMGQALSVDMHMLTVEAAAIQNLVRCVQRCDLELAGIASSAYVSGISALVEDEQELG
AACIDMGGGTTSVSIFMKKHMIYADAVRMGGDHVTSDISMGLGVPTATAERIKTMSGGVHATGADDRDMIDIGGETGDWE
RDRRTVSRAELIGIMRPRVEEILEEVRVRLDAAGFDHLPSQQIVLTGGSSQILGLDGLASRILGQQVRLGRPMRVHGLPQ
AVTGPGFASAVGMCLFAAHPQDEWWDFDAPVDRMAGGSMRRVVRWFKDNW

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=442, Percent_Identity=26.0180995475113, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 48647; Mature: 48647

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAPIDMTDLYQSQRAMRQMRRQAMQRGVVAILDVGSSKISCLVLRFDGVTRLSEDNSIG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEECCCEECCCCCCCH
SLAGQSGFRVIGAATTRSRGVQFGEVCAMQETERAIRTAVQAAQKMAEVRVDHVIACFAG
HHCCCCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPRSYGLDATVELEGQEVTENEIARVLAACEVPEYGAGREVLHAQPVNFALDNRSGLED
HCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEECCCCCCCC
PRGQMGQALSVDMHMLTVEAAAIQNLVRCVQRCDLELAGIASSAYVSGISALVEDEQELG
CHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHCHHHHC
AACIDMGGGTTSVSIFMKKHMIYADAVRMGGDHVTSDISMGLGVPTATAERIKTMSGGVH
HHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEE
ATGADDRDMIDIGGETGDWERDRRTVSRAELIGIMRPRVEEILEEVRVRLDAAGFDHLPS
ECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QQIVLTGGSSQILGLDGLASRILGQQVRLGRPMRVHGLPQAVTGPGFASAVGMCLFAAHP
CEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCC
QDEWWDFDAPVDRMAGGSMRRVVRWFKDNW
CCCCCCCCCCHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRAPIDMTDLYQSQRAMRQMRRQAMQRGVVAILDVGSSKISCLVLRFDGVTRLSEDNSIG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEECCCEECCCCCCCH
SLAGQSGFRVIGAATTRSRGVQFGEVCAMQETERAIRTAVQAAQKMAEVRVDHVIACFAG
HHCCCCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPRSYGLDATVELEGQEVTENEIARVLAACEVPEYGAGREVLHAQPVNFALDNRSGLED
HCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEECCCCCCCC
PRGQMGQALSVDMHMLTVEAAAIQNLVRCVQRCDLELAGIASSAYVSGISALVEDEQELG
CHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHCHHHHC
AACIDMGGGTTSVSIFMKKHMIYADAVRMGGDHVTSDISMGLGVPTATAERIKTMSGGVH
HHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEE
ATGADDRDMIDIGGETGDWERDRRTVSRAELIGIMRPRVEEILEEVRVRLDAAGFDHLPS
ECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QQIVLTGGSSQILGLDGLASRILGQQVRLGRPMRVHGLPQAVTGPGFASAVGMCLFAAHP
CEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCC
QDEWWDFDAPVDRMAGGSMRRVVRWFKDNW
CCCCCCCCCCHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]