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The map label for this gene is ftsW [H]

Identifier: 99080522

GI number: 99080522

Start: 729001

End: 730170

Strand: Direct

Name: ftsW [H]

Synonym: TM1040_0681

Alternate gene names: 99080522

Gene position: 729001-730170 (Clockwise)

Preceding gene: 99080520

Following gene: 99080523

Centisome position: 22.77

GC content: 60.51

Gene sequence:

>1170_bases
ATGACTGAGATGGTCTATGGCGCGCTTCCCGCGCAAGAGGGGGAGCCGATCCTCCCGAAATGGTGGCGGACACTGGACAA
GTGGACGATGACTTTCATCGTTACCCTGTTTGTGATCGGCTTGCTTTTGGGGCTTGCGGCTTCGGTCCCGCTGGCGGCGC
GCAACGGGTTTGACAACTTCCACTATGTGCAGCGACAGGCCTTCTTTGGGAGCACGGCGCTGGTGGCGATGGTGCTCACG
TCTATGATGTCACCCACCTTGGTGCGCAGGTTGGCGGTCATCGGGTTTATCTTTGCCTTTGTGGCGCTTGCCTTCCTGCC
GATCTTTGGCACGGACTTCGGCAAAGGCGCAGTGCGCTGGTACAGTCTGGGCTTTGCCTCGGTACAGCCGTCGGAATTCC
TGAAGCCCGGTTTTGTGGTGCTGGCCGCATGGATGATTGCCGCCAGCCAACAGATCTATGGGCCGCCGGGCACGCTGTTG
TCCTTTGGTCTCTGCATGGCGGTGGTGATGCTTTTGGTGATGCAGCCCGACTTTGGTCAGGCCTGCCTCATTCTCTTTGG
TTGGGGGGTCATGTATTTTGTCGCGGGCGCGCCGATGCTGTTGCTTGTGGGGATGGCCGGGGTTGTCATTATCGGCGGCG
TCATCGCCTATTCCAACTCAGAGCACTTCGCCCGCCGCATCGATGGCTTCCTGAGCCCTGATCTCGACCCCACCACGCAG
CTTGGCTATGCGACCAATGCGATCCGCGAGGGCGGATTGTTTGGTGTCGGCGTCGGCGAGGGGCAGGTGAAATGGTCGCT
GCCGGATGCGCATACCGATTTCATCATTGCTGTAGCTGCCGAGGAATACGGGCTGGTGCTCGTCTCCATCATCATCTTCC
TCTATGCGATGATCGTTGTGCGCTCGCTGTTCCGCCTGATGCGCGAGCGGGACACATTCATCCGCCTTGCCGGTGCGGGG
CTTGCCTGCACTTTTGGGGTTCAGGCGATGATCAACATGGGCGTTGCGGTGCGTCTTCTGCCTGCGAAAGGCATGACTTT
GCCGTTCGTGAGCTACGGTGGCTCCTCCCTCATTGCAGGCGGCATCGCGATGGGTATGCTCCTGGCCTTCACACGGACCC
GACCTCAGGGCGAAATCGCGGACGCATTGCGCGGACGCGGGCGCGGCTGA

Upstream 100 bases:

>100_bases
GTGTCAATCACGGTACACTTTGACTAATAAGTTCCAAAACCGGGACACATTGAGGCAAAACAGGCCCCTCATTTTGGGGT
CCAACAAAGGCAGTGAACCC

Downstream 100 bases:

>100_bases
GCATGGTGGTCCGGTCAACGGACAAGAAGACGAAGGCAGGCACGAGATGACACAGAAACTGCTCCTGATGGCGGCAGGCG
GCACCGGGGGGCATATGTTC

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTEMVYGALPAQEGEPILPKWWRTLDKWTMTFIVTLFVIGLLLGLAASVPLAARNGFDNFHYVQRQAFFGSTALVAMVLT
SMMSPTLVRRLAVIGFIFAFVALAFLPIFGTDFGKGAVRWYSLGFASVQPSEFLKPGFVVLAAWMIAASQQIYGPPGTLL
SFGLCMAVVMLLVMQPDFGQACLILFGWGVMYFVAGAPMLLLVGMAGVVIIGGVIAYSNSEHFARRIDGFLSPDLDPTTQ
LGYATNAIREGGLFGVGVGEGQVKWSLPDAHTDFIIAVAAEEYGLVLVSIIIFLYAMIVVRSLFRLMRERDTFIRLAGAG
LACTFGVQAMINMGVAVRLLPAKGMTLPFVSYGGSSLIAGGIAMGMLLAFTRTRPQGEIADALRGRGRG

Sequences:

>Translated_389_residues
MTEMVYGALPAQEGEPILPKWWRTLDKWTMTFIVTLFVIGLLLGLAASVPLAARNGFDNFHYVQRQAFFGSTALVAMVLT
SMMSPTLVRRLAVIGFIFAFVALAFLPIFGTDFGKGAVRWYSLGFASVQPSEFLKPGFVVLAAWMIAASQQIYGPPGTLL
SFGLCMAVVMLLVMQPDFGQACLILFGWGVMYFVAGAPMLLLVGMAGVVIIGGVIAYSNSEHFARRIDGFLSPDLDPTTQ
LGYATNAIREGGLFGVGVGEGQVKWSLPDAHTDFIIAVAAEEYGLVLVSIIIFLYAMIVVRSLFRLMRERDTFIRLAGAG
LACTFGVQAMINMGVAVRLLPAKGMTLPFVSYGGSSLIAGGIAMGMLLAFTRTRPQGEIADALRGRGRG
>Mature_388_residues
TEMVYGALPAQEGEPILPKWWRTLDKWTMTFIVTLFVIGLLLGLAASVPLAARNGFDNFHYVQRQAFFGSTALVAMVLTS
MMSPTLVRRLAVIGFIFAFVALAFLPIFGTDFGKGAVRWYSLGFASVQPSEFLKPGFVVLAAWMIAASQQIYGPPGTLLS
FGLCMAVVMLLVMQPDFGQACLILFGWGVMYFVAGAPMLLLVGMAGVVIIGGVIAYSNSEHFARRIDGFLSPDLDPTTQL
GYATNAIREGGLFGVGVGEGQVKWSLPDAHTDFIIAVAAEEYGLVLVSIIIFLYAMIVVRSLFRLMRERDTFIRLAGAGL
ACTFGVQAMINMGVAVRLLPAKGMTLPFVSYGGSSLIAGGIAMGMLLAFTRTRPQGEIADALRGRGRG

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=340, Percent_Identity=30.2941176470588, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786853, Length=315, Percent_Identity=31.7460317460317, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41859; Mature: 41728

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TEMVYGALPAQEGEPILPKWWRTLDKWTMTFIVTLFVIGLLLGLAASVPLAARNGFDNF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHH
HYVQRQAFFGSTALVAMVLTSMMSPTLVRRLAVIGFIFAFVALAFLPIFGTDFGKGAVRW
HHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
YSLGFASVQPSEFLKPGFVVLAAWMIAASQQIYGPPGTLLSFGLCMAVVMLLVMQPDFGQ
EECCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCH
ACLILFGWGVMYFVAGAPMLLLVGMAGVVIIGGVIAYSNSEHFARRIDGFLSPDLDPTTQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCCCCCCCHH
LGYATNAIREGGLFGVGVGEGQVKWSLPDAHTDFIIAVAAEEYGLVLVSIIIFLYAMIVV
HHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
RSLFRLMRERDTFIRLAGAGLACTFGVQAMINMGVAVRLLPAKGMTLPFVSYGGSSLIAG
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEECCCCCHHHHH
GIAMGMLLAFTRTRPQGEIADALRGRGRG
HHHHHHHHHHHCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]