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The map label for this gene is murG

Identifier: 99080523

GI number: 99080523

Start: 730217

End: 731314

Strand: Direct

Name: murG

Synonym: TM1040_0682

Alternate gene names: 99080523

Gene position: 730217-731314 (Clockwise)

Preceding gene: 99080522

Following gene: 99080524

Centisome position: 22.81

GC content: 65.3

Gene sequence:

>1098_bases
ATGACACAGAAACTGCTCCTGATGGCGGCAGGCGGCACCGGGGGGCATATGTTCCCCGCGCAGGCCTTGGCCGAGGCGAT
GCTGCGCAAGGGCTGGCGGGTGAAGCTCTCGACGGACCCGCGCGGTGCACGCTACACGGGCGGCTTTCCTCATATGACCG
AGATCACGGAGGTCTCCTCGGCGACATTTGCGCGAGGCGGGCTGCTGGCAAAGGCCATGGTCGCGCCGCGGATCGCCGCC
GGCGTTGCGTCTATGGCGATGCAGATGCGCCGCGACCGGCCCGATGTGGTGATCGGCTTTGGCGGCTATCCGTCCATTCC
GGCACTCGGGGCAGCGACGCTTCTGGGACTGCCGCGCATGATCCACGAGCAAAACGGCGTGCTTGGCAAAGTGAACCAGA
AATTTGCAACCCGCGTGGCCGAAGTGGCCTGCGGCGTCTGGCCCACGGACTTACCCGCAGGTGCCGAGGGTATTCATGTC
GGCAATCCGGTGCGGGCCGCCGTTCTGGAGCGCCAGGGCGCGCCCTATATCCCGCCCGGCGATTATCCGATGTCGCTTCT
GGTGATGGGCGGCAGCCAGGGCGCGCGTATCCTGTCGGATGTGGTTCCCGGAGCCATCGCGGCGCTGCCCGAGACCTTGC
GCCGCCATCTGCGCGTCAGCCATCAGGCCCGCGAAGAGGATATGGCACGGGTTGCGCAGTTTTATGCCGACGCAGGAATT
GATGCCGAGGTCCAGACCTTCTTTGCCGATGTGCCGTCGCGGATCTCCGAGGCGCAGCTGGTGATCTCGCGCTCCGGGGC
GTCCTCGATTGCGGATATTTCGGTGATCGGCCGTCCGTCGATCCTGATCCCGCTGGCCACGGCCGCAGGCGACCATCAAA
CCGCGAATACCCGAGGGCTGGTTGAGGCCGGAGGCGCGATCCGTATTCCCGAGAGCGCCCTTGACACCACCTCGCTTGCA
GAGCAAATCGCCGCAGTCCTGACCAATGCCGAAGGGGCCACGCAGATGGCCCATGCCGCTTTGAGCACAGGCATTCCAGA
TGCCACGGAACGTCTTGTGGCGCGTGTTGAACATTTGTCCGAGGAAGCTGCCCCATGA

Upstream 100 bases:

>100_bases
ACCCGACCTCAGGGCGAAATCGCGGACGCATTGCGCGGACGCGGGCGCGGCTGAGCATGGTGGTCCGGTCAACGGACAAG
AAGACGAAGGCAGGCACGAG

Downstream 100 bases:

>100_bases
CCCCTGCCACCAAACTGCCCGGCGACGTCGGCCCGATCCATTTTGTCGGTATTGGCGGCATCGGGATGTCTGGCATCGCC
GAGGTGCTTTTGAACCTTGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTQKLLLMAAGGTGGHMFPAQALAEAMLRKGWRVKLSTDPRGARYTGGFPHMTEITEVSSATFARGGLLAKAMVAPRIAA
GVASMAMQMRRDRPDVVIGFGGYPSIPALGAATLLGLPRMIHEQNGVLGKVNQKFATRVAEVACGVWPTDLPAGAEGIHV
GNPVRAAVLERQGAPYIPPGDYPMSLLVMGGSQGARILSDVVPGAIAALPETLRRHLRVSHQAREEDMARVAQFYADAGI
DAEVQTFFADVPSRISEAQLVISRSGASSIADISVIGRPSILIPLATAAGDHQTANTRGLVEAGGAIRIPESALDTTSLA
EQIAAVLTNAEGATQMAHAALSTGIPDATERLVARVEHLSEEAAP

Sequences:

>Translated_365_residues
MTQKLLLMAAGGTGGHMFPAQALAEAMLRKGWRVKLSTDPRGARYTGGFPHMTEITEVSSATFARGGLLAKAMVAPRIAA
GVASMAMQMRRDRPDVVIGFGGYPSIPALGAATLLGLPRMIHEQNGVLGKVNQKFATRVAEVACGVWPTDLPAGAEGIHV
GNPVRAAVLERQGAPYIPPGDYPMSLLVMGGSQGARILSDVVPGAIAALPETLRRHLRVSHQAREEDMARVAQFYADAGI
DAEVQTFFADVPSRISEAQLVISRSGASSIADISVIGRPSILIPLATAAGDHQTANTRGLVEAGGAIRIPESALDTTSLA
EQIAAVLTNAEGATQMAHAALSTGIPDATERLVARVEHLSEEAAP
>Mature_364_residues
TQKLLLMAAGGTGGHMFPAQALAEAMLRKGWRVKLSTDPRGARYTGGFPHMTEITEVSSATFARGGLLAKAMVAPRIAAG
VASMAMQMRRDRPDVVIGFGGYPSIPALGAATLLGLPRMIHEQNGVLGKVNQKFATRVAEVACGVWPTDLPAGAEGIHVG
NPVRAAVLERQGAPYIPPGDYPMSLLVMGGSQGARILSDVVPGAIAALPETLRRHLRVSHQAREEDMARVAQFYADAGID
AEVQTFFADVPSRISEAQLVISRSGASSIADISVIGRPSILIPLATAAGDHQTANTRGLVEAGGAIRIPESALDTTSLAE
QIAAVLTNAEGATQMAHAALSTGIPDATERLVARVEHLSEEAAP

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=375, Percent_Identity=33.6, Blast_Score=148, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_SILST (Q1GIV1)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_612677.1
- ProteinModelPortal:   Q1GIV1
- SMR:   Q1GIV1
- STRING:   Q1GIV1
- GeneID:   4077290
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_0682
- NMPDR:   fig|292414.1.peg.2788
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q1GIV1
- ProtClustDB:   PRK00726
- BioCyc:   SSP292414:TM1040_0682-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38068; Mature: 37937

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKLLLMAAGGTGGHMFPAQALAEAMLRKGWRVKLSTDPRGARYTGGFPHMTEITEVSS
CCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
ATFARGGLLAKAMVAPRIAAGVASMAMQMRRDRPDVVIGFGGYPSIPALGAATLLGLPRM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
IHEQNGVLGKVNQKFATRVAEVACGVWPTDLPAGAEGIHVGNPVRAAVLERQGAPYIPPG
HHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
DYPMSLLVMGGSQGARILSDVVPGAIAALPETLRRHLRVSHQAREEDMARVAQFYADAGI
CCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAEVQTFFADVPSRISEAQLVISRSGASSIADISVIGRPSILIPLATAAGDHQTANTRGL
CHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCH
VEAGGAIRIPESALDTTSLAEQIAAVLTNAEGATQMAHAALSTGIPDATERLVARVEHLS
HCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EEAAP
HHCCC
>Mature Secondary Structure 
TQKLLLMAAGGTGGHMFPAQALAEAMLRKGWRVKLSTDPRGARYTGGFPHMTEITEVSS
CCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
ATFARGGLLAKAMVAPRIAAGVASMAMQMRRDRPDVVIGFGGYPSIPALGAATLLGLPRM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
IHEQNGVLGKVNQKFATRVAEVACGVWPTDLPAGAEGIHVGNPVRAAVLERQGAPYIPPG
HHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
DYPMSLLVMGGSQGARILSDVVPGAIAALPETLRRHLRVSHQAREEDMARVAQFYADAGI
CCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAEVQTFFADVPSRISEAQLVISRSGASSIADISVIGRPSILIPLATAAGDHQTANTRGL
CHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCH
VEAGGAIRIPESALDTTSLAEQIAAVLTNAEGATQMAHAALSTGIPDATERLVARVEHLS
HCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EEAAP
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA