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The map label for this gene is gap3 [H]

Identifier: 99080366

GI number: 99080366

Start: 551302

End: 552300

Strand: Reverse

Name: gap3 [H]

Synonym: TM1040_0525

Alternate gene names: 99080366

Gene position: 552300-551302 (Counterclockwise)

Preceding gene: 99080367

Following gene: 99080365

Centisome position: 17.25

GC content: 59.46

Gene sequence:

>999_bases
ATGACCGTCTACGCAGTAAATGGCCTCGGCCGGATGGGCAAACTGGCCCTCAACCCCCTGCTCGAGCGCGGCGCTCAGAT
CGCCTGGATCAATGACGCGGTGGGCGATGCTGAAATGCACGCGCATCTTCTGGAGTTTGACACGGTTCATGGCCGCTGGG
ACGCAGAATTCACATGCGATGCCGAAAGCATCACCATCGACGGCACCCGCCTGCCCGTTCTGAACAAGACCAATCTTGCG
GATCTGCCGCTGGACGGCGTTGATGTCGTGATCGACTGTACCGGCGTTTTTAAGACCGACGCAAAGCTTGCACCTTACTT
TGAGGCTGGCGTAAAAAAGGTCGTGGTCTCTGCCCCGGTCAAGGACGGAGATGCGGCGAATATCGTGATGGGTGTCAATC
ATGACATCTATGACCCGTCCCGCCATCGGATTGTGACCGCGGCAAGCTGCACCACTAACTGCCTCGCGCCCGTGGTCAAA
GTGCTGCACGAGGGGATCGGCATCAAACACGGATCAATGACAACGATCCATGACGTAACCAATACCCAGACCATCGTGGA
CCGCCCTGCCAAGGATCTGCGGCGCGCGCGCTCGGCGCTCAACTCGCTGATCCCGACCACCACCGGCAGCGCCACGGCGA
TCACGCTGATCTACCCGGAGCTAGAAGGGAAGCTGAACGGCCACGCCGTGCGGGTGCCGCTTCTCAATGCCTCACTCACG
GATTGCGTCTTTGAGGTCGCGCGCGACACCACCGTTGAAGAGGTGAATGCCTTTTTCAAGGAGGCTGCCAATGGCGCACT
CGACGGCATCCTTGGCTATGAGCTGCGCCCGCTGGTCTCGGCCGATTACACCAACGACACGCGGTCCTCTATTGTGGATG
CGCCTTCGACCATGGTCGTGAACGGAACGCAGGTGAAGATCTATGCGTGGTACGACAATGAGATGGGCTATGCGCATCGT
CTGGTGGACGTGGCGATGATGGTGGGTGAGAGCCTGTGA

Upstream 100 bases:

>100_bases
CGGAGCTGGACCGGATTTCGCTGCAACGGGCGGTTGACGACATCGCCCGCACACACTGAAGCCCCAAGGGGCGCGACCCA
ATCGATATAAAGGACAGCAG

Downstream 100 bases:

>100_bases
CCCAATCGCCCGCGCAAAATGGCCTCGCCGCCTATATGGCGGTGACCGCAGCCTATTGGGCCTTCATGCTCACGGATGGC
GCGCTGCGCATGTTGGTGCT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTVYAVNGLGRMGKLALNPLLERGAQIAWINDAVGDAEMHAHLLEFDTVHGRWDAEFTCDAESITIDGTRLPVLNKTNLA
DLPLDGVDVVIDCTGVFKTDAKLAPYFEAGVKKVVVSAPVKDGDAANIVMGVNHDIYDPSRHRIVTAASCTTNCLAPVVK
VLHEGIGIKHGSMTTIHDVTNTQTIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELEGKLNGHAVRVPLLNASLT
DCVFEVARDTTVEEVNAFFKEAANGALDGILGYELRPLVSADYTNDTRSSIVDAPSTMVVNGTQVKIYAWYDNEMGYAHR
LVDVAMMVGESL

Sequences:

>Translated_332_residues
MTVYAVNGLGRMGKLALNPLLERGAQIAWINDAVGDAEMHAHLLEFDTVHGRWDAEFTCDAESITIDGTRLPVLNKTNLA
DLPLDGVDVVIDCTGVFKTDAKLAPYFEAGVKKVVVSAPVKDGDAANIVMGVNHDIYDPSRHRIVTAASCTTNCLAPVVK
VLHEGIGIKHGSMTTIHDVTNTQTIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELEGKLNGHAVRVPLLNASLT
DCVFEVARDTTVEEVNAFFKEAANGALDGILGYELRPLVSADYTNDTRSSIVDAPSTMVVNGTQVKIYAWYDNEMGYAHR
LVDVAMMVGESL
>Mature_331_residues
TVYAVNGLGRMGKLALNPLLERGAQIAWINDAVGDAEMHAHLLEFDTVHGRWDAEFTCDAESITIDGTRLPVLNKTNLAD
LPLDGVDVVIDCTGVFKTDAKLAPYFEAGVKKVVVSAPVKDGDAANIVMGVNHDIYDPSRHRIVTAASCTTNCLAPVVKV
LHEGIGIKHGSMTTIHDVTNTQTIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELEGKLNGHAVRVPLLNASLTD
CVFEVARDTTVEEVNAFFKEAANGALDGILGYELRPLVSADYTNDTRSSIVDAPSTMVVNGTQVKIYAWYDNEMGYAHRL
VDVAMMVGESL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=322, Percent_Identity=39.4409937888199, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI7669492, Length=324, Percent_Identity=38.8888888888889, Blast_Score=241, Evalue=6e-64,
Organism=Escherichia coli, GI1788079, Length=324, Percent_Identity=39.5061728395062, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=39.3393393393393, Blast_Score=230, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI17534677, Length=329, Percent_Identity=38.9057750759878, Blast_Score=235, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17534679, Length=329, Percent_Identity=38.2978723404255, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI32566163, Length=329, Percent_Identity=37.9939209726444, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17568413, Length=329, Percent_Identity=37.9939209726444, Blast_Score=231, Evalue=4e-61,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=40, Blast_Score=253, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=40.2985074626866, Blast_Score=253, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=39.4029850746269, Blast_Score=252, Evalue=6e-68,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=38.8379204892966, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=38.8379204892966, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=38.8379204892966, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=38.8379204892966, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=36.0606060606061, Blast_Score=231, Evalue=5e-61,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35776; Mature: 35645

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYAVNGLGRMGKLALNPLLERGAQIAWINDAVGDAEMHAHLLEFDTVHGRWDAEFTCD
CEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHEECCCCCCCCEEEEC
AESITIDGTRLPVLNKTNLADLPLDGVDVVIDCTGVFKTDAKLAPYFEAGVKKVVVSAPV
CCEEEECCCCCCEECCCCCCCCCCCCCEEEEEECCEEECCCCCCHHHHHCHHEEEEECCC
KDGDAANIVMGVNHDIYDPSRHRIVTAASCTTNCLAPVVKVLHEGIGIKHGSMTTIHDVT
CCCCCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECC
NTQTIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELEGKLNGHAVRVPLLNASLT
CCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEECCHHH
DCVFEVARDTTVEEVNAFFKEAANGALDGILGYELRPLVSADYTNDTRSSIVDAPSTMVV
HHHHHHHHCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCEECCCCCCHHHHHHCCCCEEEE
NGTQVKIYAWYDNEMGYAHRLVDVAMMVGESL
ECCEEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVYAVNGLGRMGKLALNPLLERGAQIAWINDAVGDAEMHAHLLEFDTVHGRWDAEFTCD
EEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHEECCCCCCCCEEEEC
AESITIDGTRLPVLNKTNLADLPLDGVDVVIDCTGVFKTDAKLAPYFEAGVKKVVVSAPV
CCEEEECCCCCCEECCCCCCCCCCCCCEEEEEECCEEECCCCCCHHHHHCHHEEEEECCC
KDGDAANIVMGVNHDIYDPSRHRIVTAASCTTNCLAPVVKVLHEGIGIKHGSMTTIHDVT
CCCCCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECC
NTQTIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELEGKLNGHAVRVPLLNASLT
CCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEECCHHH
DCVFEVARDTTVEEVNAFFKEAANGALDGILGYELRPLVSADYTNDTRSSIVDAPSTMVV
HHHHHHHHCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCEECCCCCCHHHHHHCCCCEEEE
NGTQVKIYAWYDNEMGYAHRLVDVAMMVGESL
ECCEEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]